Keywords: cAMP; cyclic adenosine monophosphate; CNS; central nervous system; DPCPX; 8-Cyclopentyl-1,3-dipropylxanthine; EAA; excitatory amino acid; EAAT; excitatory amino acid transporter; NMDA; N-methyl-d-aspartate; TTBS; Tween 20 Tris-Buffered Saline; adenosine;
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Keywords: NOS; nitric oxide synthase; NO; nitric oxide; eNOS; endothelial NOS; p-eNOS; phospho-eNOS; nNOS; neuronal NOS; iNOS; inducible NOS; Akt; Protein Kinase B, phospho-Akt; HIF-1α; hypoxia inducible factor α; Hsp-90; heat shock protein 90; FW; freshwater; 6m
Keywords: AGE; advanced glycation end-product; ANOVA; analysis of variance; %BF; percent body fat; DXA; dual energy X-ray absorptiometry; ECM; extracellular matrix; ET; exercise training; F344BNF1; Fischer 344 Brown Norway F1 hybrid rat; GAPDH; glyceraldehyde 3-pho
Keywords: DAPI; 4â²,6-diamidino-2-phenylindole; DCC; dicyclohexylcarbodiimide; EDC; N-(3-dimethylaminopropyl)-Nâ²-ethyl-carbodiimide; FITC; fluorescein isothiocyanate; NBT/BCIP; nitro-blue tetrazolium chloride and 5-bromo-4-chloro-3â²-indolyphosphate p-toluidine
The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A
Keywords: AC; adenylyl cyclase; AD; Alzheimer's disease; Akt; protein kinase B; Aβ; beta-amyloid; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin, CRE, cyclic AMP response element; CREB; CRE-binding protein; GABA; γ-aminobutyric acid; GFAF; glial
Increased Neuroligin 2 Levels in the Postsynaptic Membrane in Spinal Dorsal Horn may Contribute to Postoperative Pain
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; CPS; cumulative pain score; PSD-95; postsynaptic density protein 95; PWT; paw withdrawal threshold; siRNA; small interfering ribonucleic acid; TTBS; Tween/Tris-buffered saline solution; postoperati
β-N-oxalyl-L-α,β-diaminopropionic acid induces wound healing by stabilizing HIF-1α and modulating associated protein expression
Keywords: L-ODAP; Lathyrus sativus; Wound healing; Hypoxia inducible factor-1α; DAB; 3,3â²-diaminobenzidine (DAB); DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulphoxide; ECM; extracellular matrix; HIF; hypoxia-inducible factor; HRE; hypoxia response
Radix Puerariae modulates glutamatergic synaptic architecture and potentiates functional synaptic plasticity in primary hippocampal neurons
Keywords: AP-5; (2R)-amino-5-phosphonovaleric acid; ARP2; actin-related protein 2; BDNF; brain-derived neurotrophic factor; DiO; 3,3-dioctadecyloxacarbocyanine perchlorate; DIV; day in vitro; DMSO; dimethyl sulfoxide; D-PBS; Dulbecco's phosphate buffered saline; FM
Mechanisms of myeloperoxidase catalyzed oxidation of H2S by H2O2 or O2 to produce potent protein Cys-polysulfide-inducing species
Keywords: 3MST; 3-Mercaptopyruvate sulfurtransferase; ABTS; 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); BSA; bovine serum albumin; CBS; cystathione β-synthase; CHO; chinese hamster ovary; CSE; cystathione γ-lyase; DTNB; 5-5'-dithiobis(2-nitrobenzoi
Effect of axotomy and 17β-estradiol on P2X7 receptor expression pattern in the hypoglossal nucleus of ovariectomized mice
Keywords: DAPI; 4â²6-diamino-2-phenylindole; ER; estrogen receptor; NGS; normal goat serum; NHS; normal horse serum; PB; phosphate buffer; PBS; phosphate-buffered saline; SDS; sodium dodecyl sulfate; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electropho
Single exposure to cocaine impairs aspartate uptake in the pre-frontal cortex via dopamine D1-receptor dependent mechanisms
Keywords: ANOVA; analysis of variance; D1R; D1-receptor signaling; DAT; dopamine transporter; DHK; dihydrokainic acid; dl-TBOA; dl-threo-β-benzyloxyaspartate; EAA; excitatory amino acid; EAATs; EAAT transporters; EDTA; ethylenediaminetetraacetic acid; EGTA; ethyle
Green tea compound epigallo-catechin-3-gallate (EGCG) increases neuronal survival in adult hippocampal neurogenesis in vivo and in vitro
Keywords: BrdU; bromodeoxyridine; DCX; doublecortin; EGCG; Epigallo-catechin-3-gallate; TTBS; Tween 20-TBS; adult neurogenesis; EGCG; hippocampus; survival; nutrition; PI3K-Akt;
Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein
Keywords: HCV; hepatitis C virus; HCC; hepatocellular carcinoma; ROS; reactive oxygen species; Fe-NTA; ferric nitrilacetic acid; JC-1; 5,5â²,6,6â²-tetrachrolo-1,1â²,3,3â²-tetraethylbenzimidazoly-carbocyanine iodide; CCCP; carbonyl cyanide-m-chlorophenyl hydrazi
5-HT2C serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice
Keywords: EDTA; ethylenediaminetetraacetic acid; fEPSPs; field excitatory postsynaptic potentials; GSK-3β; glycogen synthase kinase-3β; FJB; fluoro-jade B; GFAP; glial fibrillary acidic protein; HFS; high frequency stimulation; 5-HIAA; 5-hydroxyindoloacetic acid;
Monitoring changes in proteome during stepwise adaptation of a MDCK cell line from adherence to growth in suspension
Keywords: 2-D DIGE; two dimensional differential gel electrophoresis; aq; aqueous; BHK; baby hamster kidney; BR; biological replicate; CDM; chemically defined medium; CHO; Chinese hamster ovary; GMEM; glasgow minimal essential medium; ERK2; extracellular signal-reg
Food, drug, insect sting allergy, and anaphylaxisPeanut defensins: Novel allergens isolated from lipophilic peanut extract
Keywords: Antifungal activity; Ara h 12; Ara h 13; food allergy; lipophilic extraction; plant defensin; peanut allergy; EST; Expressed sequence tags; PVDF; Polyvinylidene fluoride; TTBS; Tris-buffered saline with Tween 20;
Hyperosmolarity induced by high glucose promotes senescence in human glomerular mesangial cells
Keywords: SA-β-gal; senescence associated-β-galactosidase; NAC; N-acetyl-cysteine; BSA; bovine serum albumin; C12FDG; 5-dodecanoylaminofluorescein di-β-d-galactopyranoside; H2DCFDA; di chloro-di-hydrofluorescein diacetate; STZ; streptozotocin; HMC; human mesangi
Environmental enrichment induces neuroplastic changes in middle age female BalbC mice and increases the hippocampal levels of BDNF, p-Akt and p-MAPK1/2
Keywords: BDNF; brain-derived neurotrophic factor; CR; calretinin; DCX; doublecortin; EDTA; ethylenediaminetetraacetic acid; ENR; environmental enrichment; GCL; granular cell layer; NH; normal housing; PI3K; phosphatidylinositol-3-kinase; TTBS; Tween 20-TBS; ZT; Ze
Coordinated role of voltage-gated sodium channels and the Na+/H+ exchanger in sustaining microglial activation during inflammation
Keywords: VGSC; voltage-gated sodium channels; NHE; Na+/H+ exchanger; TTX; tetrodotoxin; LPS; lipopolysaccharide; MEM; minimum essential medium; KRHB; Krebs-Ringer-HEPES buffer; TTBS; Tween 20 Tris buffered saline; PBS; phosphate-buffered saline; qPCR; quantita
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells
Keywords: DAG; diacylglycerol; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; ECL; enhanced chemiluminescence; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; GAP-43; growth associated
Partial recovery of the damaged rat blood-brain barrier is mediated by adherens junction complexes, extracellular matrix remodeling and macrophage infiltration following focal astrocyte loss
Keywords: BBB; blood-brain barrier; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; PBS; phosphate-buffered saline; PECAM-1; platelet endothelial cell adhesion molecule-1; TTBS; Tris-Tween-buffered saline; VE; vascular en
Odontoblast-targeted Bcl-2 overexpression promotes dentine damage repair
Keywords: α-MEM; alpha-minimum essential medium; BCA; bicinchoninic acid assay; Bcl-2; B-cell lymphoma-2; hBcl-2; human Bcl-2; mBcl-2; mouse Bcl-2; mBax; mouse Bcl-2-associated X protein; βGP; beta-glycerophosphate; BMP; bone morphogenetic protein; BSA; bovine se
Chronic restraint stress decreases glial fibrillary acidic protein and glutamate transporter in the periaqueductal gray matter
Keywords: BSA; bovine serum albumin; CNS; central nervous system; EAAT; excitatory amino acid transporter; GFAP; glial fibrillary acidic protein; IR; immunoreactivity; LPAG; lateral PAG; PAG; periaqueductal gray matter; PB; phosphate buffer; PLSD; protected least s
Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis
Keywords: Crystal structure; Isothermal titration calorimetry; Flavonoid; Wild type TTR; TTR V30M mutant; Amyloidosis; TTR amyloid inhibitor; TTR; transthyretin; wt; wild type; V30M; Val30Met mutant; TTBS; thyroxin binding sites; HBP; halogen binding pocket; API; a
Leptin-induced downregulation of the rat hippocampal somatostatinergic system may potentiate its anorexigenic effects
Keywords: AC; adenylyl cyclase; CREB; cyclic AMP response element binding protein; Gi; GTP-binding inhibitory protein; GRK; G-protein-coupled receptor kinase; IFNγ; interferon-γ; IL; interleukin; SDS; sodium dodecyl sulfate; SOCS3; suppressor of cytokine signalin
Brazilian propolis-derived components inhibit TNF-α-mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes
Keywords: aP2; adipocyte fatty acid-binding protein 4; EMM; molecular mechanics energy; FBS; fetal bovine serum; JNK; c-Jun-NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MKK; mitogen-activated protein kinase kinase; MM-PBSA; molecular mechanics Poiss
Alaternin attenuates delayed neuronal cell death induced by transient cerebral hypoperfusion in mice
Keywords: COE; the ethanolic extract of the seeds of Cassia obtusifolia; GFAP; glial fibrillary acidic protein; NO; nitric oxide; iNOS; inducible nitric oxide synthase; NOS; nitric oxide synthase; PBS; phosphate-buffered saline; BCCAO; bilateral common carotid arte
Effect of Eicosapentaenoic Acid on E-type Prostaglandin Synthesis and EP4 Receptor Signaling Human Colorectal Cancer Cells
Keywords: AA; arachidonic acid; COX; cyclooxygenase; CRC; colorectal cancer DHA, docosahexaenoic acid; EPA; eicosapentaenoic acid; FAP; familial adenomatous polyposis; FFA; free fatty add; PG; prostaglandin; RCT; randomized controlled trial; TTBS; Tween-Tris-buffer
Antidepressant properties of the 5-HT4 receptor partial agonist, SL65.0155: Behavioral and neurochemical studies in rats
Keywords: Bcl-2; B-cell lymphoma-2; BDNF; Brain Derived Neurotrophic Factor; CNS; Central Nervous System; FST; Forced Swim Test; HRP; Horseradish Peroxidase; i.p.; intraperitoneal; NA; Noradrenaline; p-CREB; phosphorilated cAMP-Response Element Binding Protein; SDS
Saphenous Vein Conduits Harvested by Endoscopic Technique Exhibit Structural and Functional Damage
Keywords: eNOS; endothelial nitric oxide synthase; ESVH; endoscopic saphenous vein harvest; MPM; multiphoton microscopy; NO; nitric oxide; OSVH; open saphenous vein harvest; TBS; Tris-buffered saline; TTBS; Tris-Tween buffered saline; vWF; von Willebrand factor; SV
Amitriptyline induces nuclear transcription factor-κB-dependent glutamate transporter upregulation in chronic morphine-infused rats
Keywords: amitriptyline; nuclear transcription factor-kB; glutamate transporters; excitatory amino acids; microdialysis; morphine tolerance; CSF; cerebrospinal fluid; EAAC1; excitatory amino acid carrier 1; GLAST; glutamate-aspartate transporter; GLT-1; glutamate t
Tumor necrosis factor α: Activity dependent expression and promotion of cortical column sleep in rats
Keywords: barrel field; evoked response potentials; surface evoked potentials; local sleep; cortical columns; cytokine; EEG; electroencephalographic; Fos; cellular oncogene; IR; immunoreactivity; LC; locus coeruleus; NREMS; non-rapid eye movement sleep; PBS; phosph
Kinin B1 and B2 receptor expression in osteoblasts and fibroblasts is enhanced by interleukin-1 and tumour necrosis factor-α. Effects dependent on activation of NF-κB and MAP kinases
Keywords: AP-1; activator protein-1; BCA; bicinchoninic acid; BK; bradykinin; BSA; essentially fatty acid free fetal bovine serum albumin; CASE; Cellular Activation of Signalling ELISA; COX-2; cyclooxygenase-2; CRE; cyclic AMP responsive element; DALBK; des-Arg10-L
Functional analysis of cis-regulatory regions within the dioxin-inducible CYP1A promoter/enhancer region from zebrafish (Danio rerio)
Keywords: AHR; aryl hydrocarbon receptor; hAHR; human AHR; bHLH; basic helix-loop-helix; ARNT; aryl hydrocarbon receptor nuclear translocator; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; PAS; PER-ARNT-SIM; HIF; hypoxia-inducible factor; SDS-PAGE; sodium dodecyl sulf
Dexamethasone modulates the development of morphine tolerance and expression of glutamate transporters in rats
Keywords: excitatory amino acids; microdialysis; morphine tolerance; NMDA receptor; glutamate transporters; AD50; analgesic dose for 50%; CSF; cerebrospinal fluid; DEX; dexamethasone; EAA(s); excitatory amino acid(s); EAAC1; excitatory amino acid carrier; GLAST; Gl
Peroxisome Proliferator-Activated Receptors (PPARs) and related transcription factors in differentiating astrocyte cultures
Keywords: transcription factors; glycogen; lipid; brain; stem cells; differentiation; BSA; bovine serum albumin; C/EBP; CCAAT/enhancer binding protein; DIV; days in vitro; EDTA; ethylenediaminetetraacetic acid; FCS; fetal calf serum; FITC; fluorescein isothiocyanat
Modified cell ELISA to determine the solubilization of cell surface proteins: Applications in GPI-anchored protein purification
Keywords: CMC; critical micelle concentration; CS; calf serum; DRM; detergent-resistant membrane; GPI; Glycosylphosphatidyl inositol; mAb; monoclonal antibody; OG; octyl β-glucoside; PMSF; phenylmethylsulfonyl fluoride; TTBS; Tween-Tris Buffered Saline; TX-100;
The cellular distribution of the Wlds chimeric protein and its constituent proteins in the CNS
Keywords: WldS protein; Ube4b; Nmnat-1; mouse; axotomy; NF-kappaB inhibitor alpha; Wallerian degeneration; MPT; mitochondrial permeability transition pore; NAD; nicotinamide adenine dinucleotide; Nmnat-1; nicotinamide mononucleotide adenylyltransferase-1; PARP; pol
Long-term activation of c-Fos and c-Jun in optic nerve head astrocytes in experimental ocular hypertension in monkeys and after exposure to elevated pressure in vitro
Keywords: Disorders of the nervous system; Degenerative disease: other; ALTS; argon laser scarification of the trabecular meshwork; DAPI; 4â²,6-diamidino-2-phenylindole; ERK; extracellular signal-regulated kinase; ExpG; experimental glaucoma; FBS; fetal bovine ser