Keywords: مهار رشد تومور; W256; Walker-256; HPLC-UV; high pressure liquid chromatography-ultraviolet; PK/PD; pharmacokinetic/pharmacodynamic; popPK; population pharmacokinetic; TGI; Tumor Growth Inhibition; NAD; Naïve Average Data; SAEM; stochastic approximation expectation maxim
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Keywords: مهار رشد تومور; MRCLS; myxoid/round cell liposarcoma; UPS; undifferentiated pleomorphic sarcoma; CSC; cancer stem cell; hBMSC; human bone marrow-derived mesenchymal stromal/stem cell; CPT; campthotecin; STS; soft tissue sarcomas; NER; nucleotide excision repair; DSB; dou
Keywords: مهار رشد تومور; Carbon nanotubes; Docetaxel; Pharmacokinetic; Kaplan–Meier survival; Tumor growth inhibition; Anticancer activity
Keywords: مهار رشد تومور; HCC; hepatocellular carcinoma; MDR; multidrug resistance; DOX; doxorubicin; Cur; curcumin; DOX/Cur-NPs; doxorubicin and curcumin co-delivery lipid nanoparticles; DEN; diethylnitrosamine; ALT; alanine aminotransferase; AST; aspartate transaminase; P-gp; P-
Keywords: مهار رشد تومور; Curcumin formulations; Tumor vasculature targeting; Tumor growth inhibition; Liposomal drug delivery; RGDK-lipopeptides;
Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma
Keywords: مهار رشد تومور; Esophageal squamous cell carcinoma; Targeting c-Myc; JQ1; c-Myc amplification; Patient derived xenograft; ESCC; esophageal squamous cell carcinoma; BET; bromodomain and extra-terminal; IC 50; the half maximal inhibitory concentration; NGS; Next-Generation
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Keywords: مهار رشد تومور; PDGFR kinase; Type II inhibitor; Kinase inhibitor; CEL; PDGFR; platelet-derived growth factor receptor; RTK; Receptor Tyrosine Kinases; ABL kinase; Abelson kinase; KIT kinase; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; RTK; receptor ty
Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors
Keywords: مهار رشد تومور; FGFR; VEGFR; Synergistic effect; Tumor growth inhibition; Lucitanib;
Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors
Keywords: مهار رشد تومور; Selective survivin inhibitors; Structure-activity relationships; Antiproliferative activities; P-glycoprotein overexpression; ABC; ATP-binding cassette; IAP; inhibitor of apoptosis proteins; P-gp; P-glycoprotein; RI; resistance index; SAR; structure-activ
Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition
Keywords: مهار رشد تومور; Rhodospirillum rubrum l-asparaginase; hTERT; Telomerase; Telomere length; Antitumor activity; IU/ml; International Units per 1Â ml; MTT; 3-(4,5-di-methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; RrA; Rhodospirillum rubrum asparaginase mutant E149R, V
Novel phosphonate analogs of sulforaphane: Synthesis, in vitro and in vivo anticancer activity
Keywords: مهار رشد تومور; AITC; allyl isothiocyanate; ALT; alanine transaminase; An V; annexin V; ANOVA; analysis of variances; APC; allophycocyanin; AST; aspartate transaminase; b.w.; body weight; BITC; benzyl isothiocyanate; BTMS; bromotrimethylsilane; BuITC; butyl isothiocyanat
FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Ex
Keywords: مهار رشد تومور; NSCLC; Non-small-cell lung cancer; TGI; Tumor growth inhibition; MEM; Minimal essential media; DMEM; Dulbecco's modified Eagle medium; FBS; Fetal bovine serum; CS-FBS; Charcoal-filtered FBS-fetal bovine serum; IMDM; Iscove's modified Eagle medium; LC-MS
In vitro and in vivo evaluation of drug-eluting microspheres designed for transarterial chemoembolization therapy
Keywords: مهار رشد تومور; Poly(lactic acid) microspheres; Controlled local drug release; Tumor growth inhibition; Chemoembolization; Biodegradation
Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model
Keywords: مهار رشد تومور; Neuropilin; Protein–protein interaction; Fully organic inhibitors; Tumor growth inhibition
Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma
Keywords: مهار رشد تومور; Berberine; miR-23a; p53; Tumor growth inhibition; Hepatocellular carcinoma;
Simultaneous delivery of doxorubicin and curcumin encapsulated in liposomes of pegylated RGDK-lipopeptide to tumor vasculature
Keywords: مهار رشد تومور; Pegylated RGDK-lipopeptide; Curcumin-doxorubicin synergy; Tumor growth inhibition; Targeting tumor vasculature; Anti-angiogenic chemotherapy;
The cancer targeting potential of d-α-tocopheryl polyethylene glycol 1000 succinate tethered multi walled carbon nanotubes
Keywords: مهار رشد تومور; Carbon nanotubes; Doxorubicin hydrochloride; Vitamin E; Kaplan–Meier survival; Tumor growth inhibition; Anticancer activity
Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases
Keywords: مهار رشد تومور; Furopyridines; Tyrosine kinase inhibitor; Tumor growth inhibition; cMET; RON;
Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays
Keywords: مهار رشد تومور; ALAS1; Aminolevulinate, delta- synthase-1; Cq; quantification cycle; FFPET; formalin-fixed paraffin-embedded tissue; HER2; human epidermal growth factor receptor 2; HPRT1; hypoxanthine phosphoribosyltransferase-1; PHC; personalized health care; qPCR; quan
FNC, a novel nucleoside analogue inhibits cell proliferation and tumor growth in a variety of human cancer cells
Keywords: مهار رشد تومور; Nucleoside analogues; Apoptosis; DNA synthesis; FNC; Tumor growth inhibition
Synthesis and biological evaluation of new 4β-anilino-4â²-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents
Keywords: مهار رشد تومور; 4β-Anilino-4â²-O-demethyl-4-desoxypodophyllotoxin derivative; Cytotoxicity; Drug resistance; Tumor growth inhibition;
High antiangiogenic and low anticoagulant efficacy of orally active low molecular weight heparin derivatives
Keywords: مهار رشد تومور; Low molecular weight heparin; Deoxycholic acid; Oral delivery; Antiangiogenesis; Tumor growth inhibition
Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa
Keywords: مهار رشد تومور; Inula racemosa; Compositae; Cytotoxicity; Tumor growth inhibition; Apoptosis
Synthesis and evaluation of indole, pyrazole, chromone and pyrimidine based conjugates for tumor growth inhibitory activities – Development of highly efficacious cytotoxic agents
Keywords: مهار رشد تومور; Cancer; Hybrid molecules; Tumor growth inhibition
Anticancer activity of an essential oil from Cymbopogon flexuosus
Keywords: مهار رشد تومور; Cymbopogon flexuosus; Essential oil; Cytotoxicity; Tumor growth inhibition; Apoptosis
Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors
Keywords: مهار رشد تومور; Imidazopyrazines; Insulin-like growth factor-I receptor; IGF-IR; IGF-1R; Tyrosine kinase inhibitor; Tumor growth inhibition; Cancer
Improved systemic pharmacokinetics, biodistribution, and antitumor activity of CpG oligodeoxynucleotides complexed to endogenous antibodies in vivo
Keywords: مهار رشد تومور; CpG oligodeoxynucleotides; Intravenous pharmacokinetics; Monomeric immune complexes; Tissue distribution; Tumor growth inhibition
Different anticancer effects of fluvastatin on primary hepatocellular tumors and metastases in rats
Keywords: مهار رشد تومور; Fluvastatin; Hepatocarcinoma; Metastasis; Pyruvate kinase; Rat; Tumor growth inhibition;