Keywords: VSMCs، سلول های عضلانی صاف عروقی; HHcy, high homocysteine; VSMCs, vascular smooth muscle cells; H2S, hydrogen sulfide; CaSR, calcium-sensing receptor; CSE, cystathionine-gamma-lyase; [Ca2+]i, intracellular calcium ion; PIP2, phosphatidylinositol biphosphate; DAG, diacylglycerol; IP3, inos
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Keywords: VSMCs، سلول های عضلانی صاف عروقی; GACI, Generalized arterial calcification of infancy; ENPP1, ectonucleotide pyrophosphatase/phosphodiesterase 1; NPPH, nucleotide pyrophosphohydrolase; PPi, inorganic pyrophosphate; VSMCs, vascular smooth muscle cells; ARHR2, autosomal recessive hypophosph
miR-125b targets DNMT3b and mediates p53 DNA methylation involving in the vascular smooth muscle cells proliferation induced by homocysteine
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, Vascular Smooth Muscle Cells; AS, atherosclerosis; Hcy, homocysteine; HHcy, Hyperhomocysteinemia; DNMT3b, DNA (cytosine-5)-methyltransferase 3b; nMS-PCR, nested methylation-specific-PCR; UTR, untranslated region; miRNAs, microRNAs; mfe, minimum fre
Shh mediates PDGF-induced contractile-to-synthetic phenotypic modulation in vascular smooth muscle cells through regulation of KLF4
Keywords: VSMCs، سلول های عضلانی صاف عروقی; PDGF, platelet-derived growth factor; VSMCs, vascular smooth muscle cells; Shh, sonic hedgehog; Gli2, Gli family zinc finger 2; Tpm 4, tropomyosin 4; KLF4, Kru¨ppel-like factor 4; SRF, serum response factor; PDGF-BB, platelet-derived growth factor BB; PDG
The role of vascular peroxidase 1 in ox-LDL-induced vascular smooth muscle cell calcification
Keywords: VSMCs، سلول های عضلانی صاف عروقی; Vascular peroxidase 1; Osteogenic differentiation; Vascular calcification; Oxidized low-density lipoprotein; Vascular smooth muscle cellsROS, reactive oxygen species; VSMCs, vascular smooth muscle cells; HOCl, hypochlorous acid; H2O2, hydrogen peroxide; o
The human ATF1 rs11169571 polymorphism increases essential hypertension risk through modifying miRNA binding
Keywords: VSMCs، سلول های عضلانی صاف عروقی; ATF1, activating transcription factor-1; EH, essential hypertension; SNP, single nucleotide polymorphism; NOX1, NADPH oxidase 1; ROSs, radical oxygen species; miRNA, microRNA; VSMCs, vascular smooth muscle cells; SBP, systolic blood pressure; DBP, diastol
Farrerol can attenuate the aortic lesion in spontaneously hypertensive rats via the upregulation of eNOS and reduction of NAD(P)H oxidase activity
Keywords: VSMCs، سلول های عضلانی صاف عروقی; SHR, spontaneously hypertensive rats; WKY, Wistar-Kyoto rats; SBP, systolic blood pressure; MT, media thickness; NO, nitric oxide; NOS, nitric oxide synthase; eNOS, endothelial nitric oxide synthase; VSMCs, vascular smooth muscle cells; NADPH, nicotinamid
Dipeptidyl peptidase-4 inhibition by gemigliptin prevents abnormal vascular remodeling via NF-E2-related factor 2 activation
Keywords: VSMCs، سلول های عضلانی صاف عروقی; DPP-4, dipeptidyl peptidase 4; GLP-1, glucagon like peptide 1; VSMCs, vascular smooth muscle cells; Gemi, gemigliptin; HO-1, heme oxygenase-1; NQO1, NAD(P)H quinone oxidoreductase 1; Nrf2, NF-E2-related factor 2Gemigliptin (PubChem CID: 11953153)Anti-oxid
Angiotensin-(1–7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway
Keywords: VSMCs، سلول های عضلانی صاف عروقی; Ang-(1–7), angiotensin-(1–7); Ang II, angiotensin II; RAS, renin angiotensin system; ACE2, angiotensin converting enzyme 2; BP, blood pressure; VSMCs, vascular smooth muscle cells; HBVSMCs, human brain vascular smooth muscle cells; ICH, intracerebral hemo
Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the JNK and p38 signaling pathways
Keywords: VSMCs، سلول های عضلانی صاف عروقی; Ginsenoside Rb1 (PubChem CID: 9898279); Ginsenoside Rg1 (PubChem CID: 441923)AAA, abdominal aortic aneurysm; ECM, extracellular matrix; MMP, matrix metalloproteinase; VSMCs, vascular smooth muscle cells; PDS, 20(S)-protopanaxadiol saponins; PTS, 20(S)-pro
Induction of Nur77 by hyperoside inhibits vascular smooth muscle cell proliferation and neointimal formation
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, vascular smooth muscle cells; NR4A, nuclear receptor 4A family; ChiP, Chromatin immunoprecipitation; CREB, cAMP response element-binding; HUVECs, human umbilical vein endothelial cells; MEK, MAP Kinase Kinase; qRT-PCR, quantitative reverse transcri
Urotensin II-induced collagen synthesis in cultured smooth muscle cells from rat aortic media and a possible involvement of transforming growth factor-β1/Smad2/3 signaling pathway
Keywords: VSMCs، سلول های عضلانی صاف عروقی; UII, urotensin II; UT, UII receptor (GPR14); MAPK, mitogen-activated protein kinase; (ERK), extracellular signal regulated kinase; TGF-β1, transforming growth factor-β1; VSMCs, vascular smooth muscle cells; DMEM, Dulbecco's modified Eagle's medium; PBS, p
Endothelial permeability in vitro and in vivo: Protective actions of ANP and omapatrilat in experimental atherosclerosis
Keywords: VSMCs، سلول های عضلانی صاف عروقی; ANP, atrial natriuretic peptide; GC-A, guanylyl cyclase-A receptor; cGMP, cyclic guanosine monophosphate; ECP, endothelial cell permeability; EC, endothelial cell; VSMCs, vascular smooth muscle cells; NEP, neprilysin; ACE, angiotensin converting enzyme; N
Role of AMPK activation in oxidative cell damage: Implications for alcohol-induced liver disease
Keywords: VSMCs، سلول های عضلانی صاف عروقی; AMPKK, AMP-activated protein kinase kinase; PKA/PKB, Protein Kinase A/B; VSMCs, Vascular Smooth Muscle Cells; BrdU, 5-bromo-2′-deoxyuridine; PI3K, Phosphatidylinositide 3-kinase; VDAC, Voltage-dependent anion channels; ANT, Adenine Nucleotide Translocase;
The anti-atherosclerotic di-peptide, Trp-His, inhibits the phosphorylation of voltage-dependent L-type Ca2+ channels in rat vascular smooth muscle cells
Keywords: VSMCs، سلول های عضلانی صاف عروقی; Di-peptide; Intracellular Ca2+; L-type Ca2+ channel; Calmodulin-dependent kinase II; Phos-tagPLC, phospholipase C; VSMCs, vascular smooth muscle cells; CaMK II, calmodulin-dependent kinase II; VDCC, voltage-dependent L-type Ca2+ channels; Ang II, angioten
SOX9 and myocardin counteract each other in regulating vascular smooth muscle cell differentiation
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, vascular smooth muscle cells; SRF, serum response factor; Myocd, myocardin; SOX9, SRY-type high mobility group box 9; qRT-PCR, quantitative reverse-transcription PCRSmooth muscle cell differentiation; SRF; Myocardin; CArG box; SOX9; Chondrogenesis;
Relaxation of rat thoracic aorta by fibrate drugs correlates with their potency to disturb intracellular calcium of VSMCs
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, vascular smooth muscle cells; Gem, gemfibrozil; [Ca2 +]i, intracellular calcium; Fa, fenofibric acid; Beza, bezafibrate; ECs, endothelium cells; DMEM, Dulbecco's modified Eagle's medium; FBS, Fetal bovine serum; Phe, phenylephrine; Ach, acetylcholi
Pioglitazone prevents hyperglycemia induced decrease of AdipoR1 and AdipoR2 in coronary arteries and coronary VSMCs
Keywords: VSMCs، سلول های عضلانی صاف عروقی; PIO, pioglitazone; VSMCs, vascular smooth muscle cells; SD, Sprague–Dawley; STZ, Streptozotocin; DM, diabetic mellitus; APN, adiponectin; FSI, fasting serum insulin; AdipoR, adiponectin receptor; PPAR-γ, peroxisome proliferator-activated receptor; AMPK, 5
Mechanism of alkalosis-induced constriction of rat cerebral penetrating arterioles
Keywords: VSMCs، سلول های عضلانی صاف عروقی; NHE, Na+/H+ exchanger; NKA, Na+/K+-adenosine triphosphatase; NCX, Na+/Ca2+ exchanger; VSMCs, vascular smooth muscle cells; MCA, middle cerebral artery; KCa channel, calcium-activated potassium channel; KATP channel, ATP-sensitive potassium channel; [Ca2+]
Tissue factor pathway inhibitor-2 is downregulated by ox-LDL and inhibits ox-LDL induced vascular smooth muscle cells proliferation and migration
Keywords: VSMCs، سلول های عضلانی صاف عروقی; TFPI-2, tissue factor pathway inhibitor-2; VSMCs, vascular smooth muscle cells; ox-LDL, oxidized low density lipoprotein; MMP, matrix metalloproteinase; FAK, focal adhesion kinasetissue factor pathway inhibitor-2 (TFPI-2); vascular smooth muscle cells (VS
Involvement of profilin-1 in angiotensin II-induced vascular smooth muscle cell proliferation
Keywords: VSMCs، سلول های عضلانی صاف عروقی; SHRs, spontaneously hypertensive rats; WKY, Wistar Kyoto rats; SBP, Systolic blood pressure; RASMCs, Rat aortic smooth muscle cells; VSMCs, vascular smooth muscle cells; Ang II, angiotensin II; ECs, endothelial cells; MTT, 3-(4,5-dim-ethylthiazol-2-yl)-2,
Trp-His, a vasorelaxant di-peptide, can inhibit extracellular Ca2+ entry to rat vascular smooth muscle cells through blockade of dihydropyridine-like l-type Ca2+ channels
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, vascular smooth muscle cells; [Ca2+]i, intracellular Ca2+ concentration; VDCC, voltage-dependent l-type Ca2+ channel; Ang II, angiotensin II; 2-APB, 2-aminoethoxydiphenylborate; DMEM, Dulbecco's Modified Eagle's Medium; FBS, fetal bovine serum; PAA
Endothelin-1 induces connective tissue growth factor expression in cardiomyocytes
Keywords: VSMCs، سلول های عضلانی صاف عروقی; ET-1, Endothelin-1; CTGF, Connective tissue growth factor/CCN2; ECM, extracellular matrix; VSMCs, vascular smooth muscle cells; AP-1, activator protein 1; EGFR, epidermal growth factor receptor; DCN, decorinEndothelin-1; Connective tissue growth factor; C
Roscovitine inhibits ERK1/2 activation induced by angiotensin II in vascular smooth muscle cells
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, vascular smooth muscle cells; Ang II, angiotensin II; FBS, fetal bovine serum; DMSO, dimethyl sulfoxide; ERK1/2, extracellular signal-regulated kinase1/2; STAT5, signal transducer and activator of transcription 5Roscovitine; Vascular smooth muscle
LPS induces inflammatory responses in human aortic vascular smooth muscle cells via Toll-like receptor 4 expression and nitric oxide production
Keywords: VSMCs، سلول های عضلانی صاف عروقی; LPS, lipopolysaccharide; TLR4, Toll-like receptor 4; VSMCs, vascular smooth muscle cells; HASMCs, human aortic smooth muscle cells; PBS, phosphate-buffered saline; ELISA, enzyme-linked immunosorbent assay; iNSO, inducible nitric oxide synthase; NOS, NO sy
Nox regulation of smooth muscle contraction
Keywords: VSMCs، سلول های عضلانی صاف عروقی; ROS, reactive oxygen species; DPI, diphenylene iodinuim; IR, inverted repeat; PTPs, protein tyrosine phosphatases; VSMCs, vascular smooth muscle cells; Ang II, Angiotensin IINox; Duox; dNox; dDuox; NADPH Oxidase; Reactive Oxygen; Drosophila; Nox1; Nox2; N
Expression and function of vascular endothelial growth factor receptors (Flt-1 and Flk-1) in vascular adventitial fibroblasts
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VEGF, vascular endothelial growth factor; PIGF, placental growth factor; HUVEC, human umbilical vein endothelial cell; DMEM, Dulbecco's modified Eagle's medium; DMSO, dimethyl sulfoxide; VSMCs, vascular smooth muscle cells; Ang II, angiotensin II; sFlt-1,
Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species
Keywords: VSMCs، سلول های عضلانی صاف عروقی; VSMCs, vascular smooth muscle cells; IGF-I, insulin-like growth factor-I; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; EGFR, epidermal growth factor receptor; GPCR, G protein-coupled receptor; ROS, reactive oxygen species;
Vascular smooth muscle migration and proliferation in response to lysophosphatidic acid (LPA) is mediated by LPA receptors coupling to Gq
Keywords: VSMCs، سلول های عضلانی صاف عروقی; ERK, extracellular signal-regulated kinase; MAPKs, mitogen-activated protein kinases; LPA, lysophosphatidic acid; ISO, isoproterenol; EGFR, epidermal growth factor receptor; GPCR, G protein-coupled receptors; VSMCs, vascular smooth muscle cells; RTK, rece