Keywords: CVDs; cardiovascular diseases; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; HPTMs; histones post-translational modifications; nt; nucleotides; 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; CpG; sequence of cytosine followed by a
مقالات ISI (ترجمه نشده)
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Keywords: 2K1C; two-kidney one-clip; ACE; angiotensin converting enzyme; ADP; adenosine diphosphate; AIH; acute intermittent hypoxia; AngII; angiotensin II; ATP; adenosine triphosphate; CIH; chronic intermittent hypoxia; CNS; central nervous system; CX3CR1; fractal
Keywords: ACE; angiotensin-converting enzyme; AET; aortic ejection time; ALT; alanine amino-transferase; AP; alkaline phosphatase; BALF; bronchoalveolar lavage fluid; BSA; bovine serum albumin; CBC; complete blood count; CK; creatine kinase; CO; cardiac output; CRP
Keywords: a7-nAChR; alpha7-nicotinic acetylcholine receptor; Ang II; angiotensin II; AP; area postrema; AR; adrenergic receptor; AT1R; angiotensin type 1 receptor; AT2R; angiotensin type 2 receptor; AV3V; anteroventral third ventricle; BBB; blood-brain barrier; CNS
Keywords: NO; nitric oxide; SNP; sodium nitroprusside; TNG; nitroglycerine; SHR; spontaneously hypertensive rats; TERPY; [Ru(terpy)(bdq)NO]3+; Eâ; endothelium-denuded; E+; endothelium-intact; 2K; sham-operated rats; 2K-1C; two-kidney one-clip, renal hypertensive
Keywords: A5; A5 catecholamine cell group; Amb; nucleus ambiguous; AP; area postrema; CNS; central nervous system; CVLM; caudal ventrolateral medulla; DAB; diaminobenzidine; DMH; dorsomedial hypothalamic nucleus; Fos-IR; Fos immunoreactivity; GAD; glutamic acid dec
Keywords: SHR; spontaneously hypertensive rats; WKY; Wistar-Kyoto rats; TES; testosterone; 5α-DHT; 5α-dihydrotestosterone; 5β-DHT; 5β-dihydrotestosterone; BP; blood pressure; L-VOCC; L-type voltage-operated Ca2+ channels; Tfm; testicular-feminized male; AR; and
Keywords: Adolescence; Anxiety; WKY; Social interaction; Anhedonia;
Keywords: ACE; angiotensin-converting enzyme; ACTH; adrenocorticotropic hormone; Ang(1-7); angiotensin (1-7); AngII; angiotensin II; AngIII; angiotensin III; AngIV; angiotensin IV; ANP; atrial natriuretic peptide; AOGEN; angiotensinogen; APA; aminopeptidase A;
Keywords: Brain; Calmodulin-related protein; Heart; Hypertension; Kidney; CaM; calmodulin; CaMK; Ca2+/CaM-dependent protein kinase; SHR; spontaneously hypertensive rats; WKY; Wistar Kyoto rats; eEF2; eukaryotic elongation factor 2; eEF2K; eEF2 kinase; DAPK; death-a
Keywords: 3[H]NE; radioactively labelled norepinephrine; LC-NE; locus-coeruleus norepinephrine; P; post-natal day; SHR; spontaneously hypertensive rat; WKY; Wistar-Kyoto rat.; SHR; WKY; ADHD; Maternal separation; GABA; NMDA;
Keywords: WKY; Wistar Kyoto; SD; Sprague-Dawley; qRT-PCR; quantitative real time polymerase chain reaction; AEA; anandamide; 2-AG; 2-arachidonoylglycerol; MAGL; monoacylglycerol lipase; FAAH; fatty acid amide hydrolase; CB1; cannabinoid receptor 1; SIH; stress-in
Keywords: Ca2 +-retention capacity; WKY; SHR; mPTP; ÎΨm; Ca2 + response;
Keywords: WAS; water avoidance stress; VMR; visceromotor responses; IC/PBS; interstitial cystitis/painful bladder syndrome; LUTS; lower urinary tract symptoms; OAB; overactive bladder; IBS; irritable bowel syndrome; WKY; Wistar-Kyoto; EMG; electromyographic; anxiet
Keywords: AAR; l-Arginine-to-ADMA ratio; ADMA; asymmetric dimethylarginine; ASR; ADMA-to-SDMA ratio; CAT; cationic amino acid transporter; DDAH; dimethylarginine dimethylaminohydrolase; NOS; nitric oxide synthase; PRMT; protein arginine methyltransferase; SDMA; sym
Keywords: 2-AG; 2-arachidonylglycerol; 5-HT; 5-hydroxytryptamine; ACC; anterior cingulate cortex; AEA; anandamide; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CB1; cannabinoid receptor 1; CB2; cannabinoid type 2; CCK; cholecystokinin; CCK2; chol
Keywords: FT; farnesyltransferase; SHR; spontaneously hypertensive rat; WKY; Wistar-Kyoto rat; FTI; farnesyltransferase inhibitor; ERK1/2; extracellular-signal regulated kinases 1/2; FPP; farnesyl pyrophosphate; MVA; mevalonate; TGF-β1; transforming growth factor-
Keywords: AIA; adjuvant-induced arthritis; Bhsp65; mycobacterial heat-shock protein 65; DEG; differentially expressed gene; QTL; quantitative trait locus; IFN; interferon; Inc; incubation; IL; interleukin; LEW; Lewis; WKY; Wistar Kyoto; LNC; lymph node cells; Med;
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; Ang-II; angiotensin II; AP-1; activator protein 1; ARIC; Atherosclerosis Risk in Communities; ATF-6; activating transcription factor-6; CAC; coronary artery calcification; CARDIA; Coronary Artery Risk Development
Intravitreal administration of endothelin type A receptor or endothelin type B receptor antagonists attenuates hypertensive and diabetic retinopathy in rats
Keywords: Endothelin; Diabetes; Diabetic retinopathy; Retinal pigment epithelium; Hypertension; Vascular leakage; VEGF; BRB; blood-retinal barrier; BQ123; endothelin type A receptor antagonist; BQ788; endothelin type B receptor antagonist; Diab; diabetic; ET-1; end
Functional regulation of large conductance Ca2+-activated K+ channels in vascular diseases
Keywords: AT1R; Angiotensin II type 1 receptors; AA; arachidonic acid; CaN; calcineurin; DHA; docosahexaenoic acid; FBXO-9; F-box only protein 9; HR; heart rate; H2O2; hydrogen peroxide; HS; hydrophobic segment; IBTX; iberiotoxin; I/R; ischemia/reperfusion; BK chan
Changes in the expression of α1B-adrenoceptor in peripheral mononuclear cells correlates with blood pressure and plasmatic homocysteine
Keywords: AR; adrenoceptor; RT; reverse transcription; PCR; polymerase chain reaction; Gapdh; glyceraldehyde-3-phosphate dehydrogenase; Ct; threshold cycle; SHR; spontaneously hypertensive rats; WKY; Wistar Kyoto; Hypertension; Alpha1 adrenoceptors; Peripheral mono
Abnormal CD161+ immune cells and retinoic acid receptor-related orphan receptor γt-mediate enhanced IL-17F expression in the setting of genetic hypertension
Keywords: Hypertension; innate immune system; Toll-like receptor; retinoic acid receptor-related orphan receptor γt; digoxin; T cells; TH17; CD161; IL-17; spontaneously hypertensive rat; gene expression; nAChR; Nicotinic acetylcholinergic receptor; PE; Phycoeryt
Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance
Keywords: BP; blood pressure; CNS; central nervous system; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinases; HR; heart rate; IRS; insulin receptor substrate; MAPK; mitogen-activated protein kinase; MEK; MAP kinase-ERK kinase; NO;
Tongxinluo improves cognition by decreasing β-amyloid in spontaneous hypertensive rats
Keywords: TXL; tongxinluo; AD; Alzheimer's disease; HTN; hypertension; SHRs; spontaneously hypertensive rats; WKY; (normotensive) Wistar Kyoto rats; RAGE; receptor for advanced glycation end products; Aβ; β-amyloid; APP; amyloid precursor protein; BBB; blood-br
Changes in plasma aldosterone and electrolytes levels, kidney epithelial sodium channel (ENaC) and blood pressure in normotensive WKY and hypertensive SHR rats following gonadectomy and chronic testosterone treatment
Keywords: CD; collecting duct; cDNA; complementary deoxyribonucleic acid; DBP; diastolic blood pressure; DCT; distal convoluted tubule; ENaC; epithelial sodium channel; G; glomerulus; MAP; mean arterial pressure; PCR; Polymerase chain reaction; PCT; proximal convol
Dipeptidyl peptidase 4 inhibitor attenuates obesity-induced myocardial fibrosis by inhibiting transforming growth factor-βl and Smad2/3 pathways in high-fat diet-induced obesity rat model
Keywords: CVD; cardiovascular disease; DIO; diet-induced obesity; DPP4i; dipeptidyl peptidase 4 inhibitor; GLP-1; glucagon-like peptide-1; HFD; high-fat diet; LV; left ventricular; RCF; rat cardiac fibroblasts; SHRs; spontaneously hypertensive rat; T2DM; type 2 dia
Atrial fibrillation is associated with hypermethylation in human left atrium, and treatment with decitabine reduces atrial tachyarrhythmias in spontaneously hypertensive rats
Keywords: AF; atrial fibrillation; AT; atrial tachyarrhythmia; BMI; body mass index; Cu, Zn-SOD; copper, zinc superoxide dismutase; GEO; Gene Expression Omnibus; GO; Gene Ontology; Hprt; hypoxanthine-guanine phosphoribosyltransferase; LA; left atrium; MnSOD; mangan
Tetrandrine, an alkaloid from S. tetrandra exhibits anti-hypertensive and sleep-enhancing effects in SHR via different mechanisms
Keywords: Tetrandrine; Hypertension; Hypnotic; Norepinephrine; SHR; spontaneously hypertensive rats; WKY; Wistar-Kyoto rat; TET; tetrandrine; W; wakefulness; TS; total sleep; LS; light sleep; SWS; slow wave sleep; REMS; rapid eye movement sleep; NREMS; non-rapid
Candesartan cilexetil attenuated cardiac remodeling by improving expression and function of mitofusin 2 in SHR
Keywords: LVH; left ventricular hypertrophy; VSMC; vascular smooth muscle cell; EH; essential hypertension; Mfn2; mitofusin 2; SHR; spontaneously hypertensive rat; WKY; Wistar-Kyoto rat; ÎÏm; mitochondrial membrane potential; ROS; reactive oxygen species; BW; bod
Alterations in the cardiac proteome of the spontaneously hypertensive rat induced by transgenic expression of CD36
Keywords: ABC; ammonium bicarbonate; ACN; acetonitrile; BLAST; Basic Local Alignment Search Tool; CBB; coomassie brilliant blue; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; 2DE; two-dimensional gel electrophoresis; DTT; dithiothreitol; EDTA; e
Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress
Keywords: ACE; angiotensin converting enzyme; AT1R; angiotensin II type 1 receptor; AT2R; angiotensin II type 2 receptor; cGMP; cyclic guanosine monophosphate; DAA-I; Des- aspartate angiotensin I; DAG; diacylgylcerol; EDCF; endothelium-derived contracting factor; E
Regular ArticleFullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats
Keywords: OH-F; fullerenol; GlcN; glucosamine; GlcN-F; glucosamine fullerene; WKY; Wistar-Kyoto-rats; SHR; spontaneously hypertensive rats; tMCAO; transient middle cerebral artery occlusion; TLR-4; toll-like receptor 4; IL-1 β; interleukin 1 β; TNF-α; tumor necr
Spatial learning in the genetically heterogeneous NIH-HS rat stock and RLA-I/RHA-I rats: Revisiting the relationship with unconditioned and conditioned anxiety
Keywords: NIH-HS; National Institutes of Health-Heterogeneous rat stock; MWM; Morris water maze; ZM; Elevated zero-maze; RHA-I; Roman High-Avoidance inbred rat; RLA-I; Roman Low-Avoidance inbred rat; WKY; Wistar-Kyoto rat; Time; Time spent in the open sections of t
Overexpression of ANO1/TMEM16A, an arterial Ca2Â +-activated Clâ channel, contributes to spontaneous hypertension
Keywords: Ang II; angiotensin II; BP; blood pressure; CA; carotid artery; CaCC; Ca2Â +-activated Clâ channel or currents; DBP; diastolic blood pressure; EH; essential hypertension; GWAS; genome-wide association studies; HLA; hind limb artery; MA; mesenteric arter
The effects of celiprolol on serum concentrations of proinflammatory cytokines in hypertensive (SHR) and normotensive (WKY) rats
Keywords: IL, interleukin; LPS, lipopolysaccharide; SHR, spontaneously hypertensive rats; TNF-α, tumor necrosis factor alpha; WKY, Wistar-Kyoto ratsCeliprolol; Proinflammatory cytokines; Lipids; SHR; WKY
Research ReportSer/thr phosphatases tonically attenuate the ERK-dependent pressor effect of ethanol in the rostral ventrolateral medulla in normotensive rats
Keywords: BP; blood pressure; HR; heart rate; OKA; okadaic acid; ACSF; artificial cerebrospinal fluid; MAPKs; mitogen-activated protein kinases; ERK; extracellular signal-regulated kinase; RVLM; rostral ventrolateral medulla; SHRs; spontaneously hypertensive; WKY;
Protective effects of N-(2-mercaptopropionyl)-glycine against ischemia-reperfusion injury in hypertrophied hearts
Keywords: MPG; Myocardial infarction; SHR; WKY; Oxidative stress; GSH; SOD; mPTP;
Neuromedin U causes biphasic cardiovascular effects and impairs baroreflex function in rostral ventrolateral medulla of spontaneously hypertensive rat
Keywords: AUC; area under the curve; BP; blood pressure; HR; heart rate; i.t.; intrathecal; MAP; mean arterial pressure; NMU; neuromedin U; NMU1; neuromedin U receptor 1; NMU2; neuromedin U receptor 2; NTS; nucleus tractus solitarius; PBS; phosphate buffered saline
N-Palmitoylethanolamide protects the kidney from hypertensive injury in spontaneously hypertensive rats via inhibition of oxidative stress
Keywords: PEA; palmitoylethanolamide; PPAR; peroxisome proliferator-activated receptor; PPRE; peroxisome proliferator response elements; Ang II; Angiotensin II; RAAS; renin-angiotensin aldosterone system; SHR; spontaneously hypertensive rats; WKY; Wistar Kyoto; SBP
Genetically determined inflammatory-response related cytokine and chemokine transcript profiles between mammary carcinoma resistant and susceptible rat strains
Keywords: DMBA; 7,12-dimethylbenz(a)anthracene; Mcs; mammary carcinoma susceptibility; RQ; relative quantification; WKY; Wistar Kyoto; WF; Wistar Furth; QPCR; quantitative polymerase chain reaction; Breast cancer susceptibility; Rat mammary carcinogenesis; Inflamma
Angiotensin-(1-7) upregulates central nitric oxide synthase in spontaneously hypertensive rats
Keywords: Ang; angiotensin; NOS; nitric oxide synthase; NO; nitric oxide; NE; norepinephrine; SNS; sympathetic nervous system; SHR; spontaneously hypertensive rats; WKY; Wistar-Kyoto; ACE; angiotensin-converting enzyme; Angiotensin-(1-7); Nitric oxide synthase; H
Effects of d-amphetamine on short- and long-term memory in spontaneously hypertensive, Wistar–Kyoto and Sprague–Dawley rats
Keywords: Memory; Attention; Hyperactivity; Autoshaping; d-Amphetamine; ADHD; SHR; STM; LTM; WKY; Sprague–Dawley; Rats
Synuclein modulation of monoamine transporters
Keywords: α-Syn; α-synuclein; β-Syn; β-synuclein; γ-Syn; γ-synuclein; AD; Alzheimer's disease; CNS; central nervous system; DA; dopamine; DAT; dopamine transporter; DMI; desipramine; MAT; presynaptic plasma membrane monoamine transporters; NAC; non-Aβ comp
Fear conditioning fragments REM sleep in stress-sensitive Wistar-Kyoto, but not Wistar, rats
Keywords: 5-HT; serotonin; ACTH; adrenocorticotropic hormone; CFC; cued fear conditioning; CORT; corticosterone; CS; conditioned stimulus; EEG; electroencephalogram; EMG; electromyogram; FST; forced swim test; HPA; hypothalamo-pituitary-adrenal axis; LC; locus coer
A potential calcium antagonist and its antihypertensive effects
Keywords: 2-APB; 2-aminoethoxydiphenyl borate; [Ca2+]i; the concentration of the intracellular free calcium; [Imp]; the concentration of Imp; BP; blood pressure; CMC; cell membrane chromatography; DBP; diastolic blood pressure; DMEM; Dulbecco's modified Eagle's med
Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression
Keywords: SD; WKY; Restraint stress; HPLC; BDNF; Open field; Forced swim test
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR
Keywords: ACE; angiotensin I converting enzyme; DOCA-salt rats; deoxycorticosterone acetate-salt hypertensive rats; AVP; arginine-vasopressin; DPI; diphenyleneiodonium; ERK1/2; extracellular regulated kinase 1 and 2; Ang II; angiotensin II; AT1; angiotensin
Vulnerability factors in anxiety: Strain and sex differences in the use of signals associated with non-threat during the acquisition and extinction of active-avoidance behavior
Keywords: AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care; ANOVA; analysis of variance; IACUC; Institutional Animal Care and Use Committee; ISI; inter-stimulus interval; ITI; inter-trial interval; LSD; least squared difference; PTSD;
Research reportResponse acquisition with signaled delayed reinforcement in a rodent model of ADHD
Keywords: Response acquisition; SHR; WKY; Spontaneously hypertensive rat; Strain differences; ADHD; Operant behavior; Delayed reinforcement;