Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity
Keywords: ساختار کریستالوگرافی اشعه ایکس; VDR; vitamin D receptor; LBD; ligand-binding domain; 1α,25-(OH)2D3; 1α,25-dihydroxyvitamin D3; SERM; selective estrogen receptor modulator; ERα; estrogen receptor α; PPARγ; peroxisome proliferator-activated receptor γ; Vitamin D; Nuclear receptor; X