دانلود مقالات ISI درباره Xbp-1 + ترجمه فارسی

ساب میگوید اختلال در عملکرد میتوکندری درگیر در اثر سمیت قلبی ناشی از متیلاسیون متیل است

Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity

Keywords: CHF; congestive heart failure; KIM; kinase interacting motif; JNK; c-Jun N-terminal Kinase; ATP; adenosine triphosphate; FRET; fluorescence resonance energy transfer; OCR; oxygen consumption rate; TMRM; tetramethylrhodamine methyl ester; eIF2α; elongatio

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

اثر کلسترول بالا و استرس تناسلی اندوپلاسمی بر بیماری های متابولیکی: یک مینی تجدید نظر شده

Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review

Keywords: ATF6; activating transcription factor 6; CHOP; C/EBP-homologous protein; CVD; cardiovascular disease; eIF2α; eukaryotic translation initiator factor 2α; ER; endoplasmic reticulum; GRP78; glucose regulated protein 78; IDL; intermediate-density lipoprotei

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

پیشرفت راهبرد های عصبی زیستی در برابر شکست پروتئازازیس: چالش های ناشی از تولید نانو

Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration

Keywords: AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se

دانلود رایگان متن کامل مقاله ISI 104 صفحه سال انتشار : 2017 سفارش ترجمه

کاهش امگا 6 در رژیم غذایی: امگا 3 باعث ایجاد پیشرفت بیماری های غیر کلاسیک چربی-کبدی در یک مدل قارچی می شود

Lowering the dietary omega-6: omega-3 does not hinder nonalcoholic fatty-liver disease development in a murine model

Keywords: Omega-6:omega-3; Nonalcoholic fatty-liver disease; High-fat diet; α-Linolenic acid; Colitis; Murine model; 4-HNE; 4-hydroxy-2-nonenal; AA; arachidonic acid; ALA; alpha-linolenic acid; ATF6; activating transcription factor 6; BiP; binding immunoglobulin p

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

اسید کلرو ساکتیک باعث ایجاد آپوپتوز در سلول های عصبی از طریق یک مسیر سیگنالینگ تنش رتیکولوم اندوپلاسمی ناشی از گونه های اکسیژن واکنشی

Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway

Keywords: CA; chloroacetic acid; LDH; lactate dehydrogenase; ER; endoplasmic reticulum; GRP; glucose-regulated protein; CHOP; C/EBP homologous protein; XBP-1; X-box binding protein 1; ATF; activation transcription factor; PERK; protein kinase R-like ER kinase; IRE-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

فروکتوز مایع از طریق اصلاح عوامل حساس کننده مواد مغذی در موش صحرایی، سوند 2 گیرنده انسولین کبد 2 و آنزیم های گلوکونئوژنیک را تنظیم می کند.

Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats

Keywords: Insulin resistance; FoxO1; XBP-1; SIRT1; p38-MAPK; mTOR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

افزایش اتوفایگی باعث کاهش استرس تناسلی اندوپلاسمی بعد از ایسکمی هیپوکسی نوزاد می شود: نقش سنتز پروتئین و مسیرهای اتوفاییک

Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: Role of protein synthesis and autophagic pathways

Keywords: ANOVA; analysis of variance; ATF-4; activating transcription factor-4; ATF-6; activating transcription factor-6; C/EBP; CCAAT/enhancer-binding protein; CHOP; C/EBP homologous protein; eIf2α; eukaryotic translation initiation factor 2 subunit α; ER; endo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

فعال شدن پاسخ استرس اندومتری رتیکولوم توسط پپتید آمیلوئید بتا 1-40 در سلولهای آندوتلیال مغز

Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells

Keywords: AD; Alzheimer's disease; AIF; apoptosis-inducing factor; AM; acetoxymethyl ester; APP; amyloid precursor protein; ATF; activating transcription factor; Aβ; amyloid-beta; BBB; blood-brain barrier; bFGF; basic fibroblast growth factor; CHOP; CAAT/enhance

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Increased mTOR cancels out the effect of reduced Xbp-1 on antibody secretion in IL-1α-deficient B cells

Keywords: IL-1α; B cells; Antibody; Xbp-1; mTOR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation

Keywords: Glucagon-like peptide-1; Exendin-4; Nuclear factor erythroid-derived 2-related factor 2; Endoplasmic reticulum stress; Nonalcoholic fatty liver disease; ATF6; Activation transcription factor-6; Bip; Binding immunoglobulin protein; CHOP; C/EBP homologous p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Decreased cytoplasmic X-box binding protein-1 expression is associated with poor prognosis and overall survival in patients with oral squamous cell carcinoma

Keywords: XBP-1; X-box binding protein-1; UPR; unfolded protein response; OSCC; oral squamous cell carcinoma; HPV; human papillomavirus; ER; endoplasmic reticulum; IRE1-α; endoribonuclease inositol-requiring enzyme 1-α; X-box binding protein-1; XBP-1; Oral squamo

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

ER stress and cancer: The FOXO forkhead transcription factor link

Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

IL-15 stimulates NKG2D while promoting IgM expression of B-1a cells

Keywords: B-1a cells; IgM; Innate signaling; Interleukin-15; IL; interleukin; i-EC; intestinal epithelial cells; i-IEL; intestinal intraepithelial lymphocytes; NK; natural killer; γc; common gamma; MΦ; macrophage; DC; dendritic cell; NKG2D; natural-killer group 2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress

Keywords: CCL5; chemokine (C-C motif) ligand 5; RANTES; regulated upon activation normal T-cell expressed and secreted; CCR5; C-C chemokine receptor type 5; NAFLD; nonalcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HFD; high-fat-diet; α-SMA; al

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Sub-cellular localization specific SUMOylation in the heart

Keywords: AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2017 سفارش ترجمه

Tyrosol, an olive oil polyphenol, inhibits ER stress-induced apoptosis in pancreatic β-cell through JNK signaling

Keywords: Tyrosol; ER stress; β-Cell failure; Apoptosis; NIT-1; ER; endoplasmic reticulum; UPR; unfolded protein response; PERK; protein kinase-like endoplasmic reticulum kinase; ATF6; activating transcription factor 6; IRE1α; inositol-requiring kinase 1α; HFD;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant

Keywords: Proteostasis; Unfolded protein response; Proteasome; Hormesis; Caenorhabditis elegans; ABU; activated in blocked unfolded protein response; ANOVA; analysis of variance; ATF-6; activating transcription factor 6; BiP; immunoglobulin binding protein; C. ele

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation

Keywords: AP; acute pancreatitis; ATF6; activating transcription factor 6; BSA; bovine serum albumin; CCK-8; cholecystokinin-8; C/EBP; CCAAT-enhancer-binding protein; CHOP; CCAAT/enhancer binding protein (C/EBP) homologous protein; eIF2; αeukaryotic translation in

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Gu-Ben-Fang-Xiao decoction attenuates sustained airway inflammation by suppressing ER stress response in a murine asthma remission model of respiratory syncytial virus infection

Keywords: GBFXD; GuBenFangXiao decoction; RSV; respiratory syncytial virus; OVA; ovalbumin; ER; endoplasmic reticulum; UPR; unfolded protein response; TCM; traditional Chinese medicine; Mont; montelukast sodium; DEX; dexamethasone; HPLC; high performance liquid chr

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells

Keywords: B cell development; DT40; Epigenetics; Gene targeting; Histone acetyltransferase; Bach2; BTB and CNC homology 2; Bcl-6; B cell lymphoma-6; Blimp-1; B lymphocyte-induced maturation protein-1; ChIP; chromatin immunoprecipitation; EBF1; early B cell factor 1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression

Keywords: Apoptosis; Bcl-2; ER stress; GCN5; Gene targeting; AFT4; activating transcription factor 4; AFT6; activating transcription factor 6; Bax; B-cell lymphoma-associated X; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra-large; CHOP; C/EBP-homologous p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals

Keywords: Armet; arginine-rich, mutated in early stage tumors; ATF4; activating transcription factor 4, a PERK downstream target; ATF6α; activating transcription factor 6α; CHOP; C/EBP homologous protein; DAPI; diamidino-2-phenylindole; EDEM1; ER degradation-enha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

IL-10-overexpressing B cells regulate innate and adaptive immune responses

Keywords: IL-10 overexpression; regulatory B cells; immune regulation; anti-inflammatory effects; immunoregulatory capacity; APC; Antigen-presenting cell; BLIMP-1; B lymphocyte-induced maturation protein 1; Br1; B regulatory 1; DC; Dendritic cell; FITC; Fluorescein

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Polyglutamine expansion disturbs the endoplasmic reticulum formation, leading to caspase-7 activation through Bax

Keywords: Apaf-1; Apoptotic protease activating factor 1; cb5; cytochrome b5; polyQ79, polyQ82; polyglutamine repeats containing proteins with 79 or 82 glutamine residues; xbp-1; x-box binding protein 1; FRET; fluorescence resonance energy transfer; Polyglutamine e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy, a new determinant of plasma cell differentiation and antibody responses

Keywords: Antibody; Atg5; Autophagy; B cell; Blimp-1; Endoplasmic reticulum; ER-phagy; Immunological memory; Multiple myeloma; Plasma cell; Proteostasis; Reticulophagy; Ubiquitin; Unfolded protein response; XBP-1; Ab; antibody; Ig; immunoglobulin; DC; dendritic cel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A sensitive assay for the biosynthesis and secretion of MANF using NanoLuc activity

Keywords: Armet; arginine-rich mutated in early stage of tumors; ER; endoplasmic reticulum; GRP78; 78-kDa glucose regulated protein; IRE1; inositol-requiring enzyme 1; MANF; mesencephalic astrocyte-derived neurotrophic factor; NanoLuc; a small nanoluciferase; RT-PC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Sumoylation regulates ER stress response by modulating calreticulin gene expression in XBP-1-dependent mode in Caenorhabditis elegans

Keywords: Sumoylation; XBP-1; UBC-9; Calreticulin; ER stress;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Unfolded protein response pathways regulate Hepatitis C virus replication via modulation of autophagy

Keywords: Hepatitis C virus; Unfolding protein response; Autophagy; eIF2-alpha; XBP-1; JNK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

ER stress-induced cell death mechanisms

Keywords: AGE; advanced glycated end-products; ALS; amyotropic lateral sclerosis; AMD; age-related macular degeneration; ARE; antioxidant response elements; ASK1; apoptotic-signaling kinase-1; ATF4; activating transcription factor 4; ATF6; activating transcription

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein

Keywords: High mobility group box-1 protein; Dendritic cell; Endoplasmic reticulum stress; XBP-1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum stress enhances γ-secretase activity

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; PS; presenilin; ATF4; activating transcription factor 4; GCN2; general control non-derepressible 2; PKR; protein kinase RNA; PERK; PKR-like ER kinase; HRI; heme-regulated inhibitor; eIF2α; eukary

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Carbon monoxide, a reaction product of heme oxygenase-1, suppresses the expression of C-reactive protein by endoplasmic reticulum stress through modulation of the unfolded protein response

Keywords: ATF6; activating transcription factor 6; CRP; C-reactive protein; CO; carbon monoxide; CORM-2; CO-releasing molecule-2 (tricarbonyl dichlororuthenium dimer); CORM-3; CO-releasing molecule-3 (tricarbonylchliro(glycinate)ruthenium); CREBH; cyclic AMP respon

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity

Keywords: BiP; binding protein (GRP78); ER; endoplasmic reticulum; ERAD; ER associated degradation; GRP94; glucose regulated protein 94; HFE; hereditary hemochromatosis protein; HLA-I; human leukocyte antigen-I; IFN-γ; interferon-γ; IL-2; interleukin-2; MHC-I; ma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Dengue infection of monocytic cells activates ER stress pathways, but apoptosis is induced through both extrinsic and intrinsic pathways

Keywords: ADE; Apoptosis; Caspase; Dengue; ER stress; XBP-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1α; inositol-requiring transmembrane kinase/endonuclease; PERK; PKR-like ER kinase; ATF6; activating transcription factor 6; XBP-1; X-Box-binding protein 1; JNK; jun N-terminal kinase; ERK; ex

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

The HPV-16 E5 protein represses expression of stress pathway genes XBP-1 and COX-2 in genital keratinocytes

Keywords: Human papillomavirus type 16; E5 oncoprotein; COX-2; IRE1α; XBP-1; ER stress response; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Evaluation of a combinatorial cell engineering approach to overcome apoptotic effects in XBP-1(s) expressing cells

Keywords: Cell engineering; CHO; Biopharmaceutical; Mammalian; Fed-batch; Cell culture; XBP-1; XIAP; Apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Stress Signaling in the Methionine-Choline-Deficient Model of Murine Fatty Liver Disease

Keywords: Steatosis; Steatohepatitis; Endoplasmic Reticulum Stress; Integrated Stress; apoB100; apolipoprotein B100; ATF6; activating transcription factor-6; Bcl-xL; B-cell lymphoma extra-large; BiP; immunoglobulin-binding protein; CHOP; C/EBP homologous protein; e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; ADPKD; autosomal dominant polycystic kidney disease; APP; amyloid precursor protein; Bax; Bcl-2-associated Xprotein; BI-1; Bax Inhibitor-1; [Ca2+]cyt; cytosolic Ca2+ concentration; [Ca2+]ER; endoplasmic-reticulum

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2010 سفارش ترجمه

Bax inhibitor-1 overexpression reduces the suppressive effect of calcium mobilizing agent on adipogenesis

Keywords: BI-1; Bax inhibitor-1; ER; endoplasmic reticulum; SERCA; sarco-endoplasmic reticulum Ca2+-ATPase; HA; hemagglutinin; THAP; thapsigargin; TUN; tunicamycin; DTT; dithiothreitol; GRP78; 78 kDa glucose-regulated protein; XBP-1; X-box binding protein-1; eIF2Î

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Protective effect against Parkinson's disease-related insults through the activation of XBP1

Keywords: Parkinson's disease; ER stress; XBP-1; MPP+/MPTP; Proteasome inhibitor; Adenoviral gene transfer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Compartmentalized expression of three novel sarco/endoplasmic reticulum Ca2+ATPase 3 isoforms including the switch to ER stress, SERCA3f, in non-failing and failing human heart

Keywords: SERCA3; Isoforms; Non-failing and failing human heart; GRP78; XBP-1; ER stress

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

C/EBP homologous protein is crucial for the acceleration of experimental pancreatitis

Keywords: Acute pancreatitis; ER stress; BiP; XBP-1; CHOP; IL-1β; LPS; Apoptosis; Caspase

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

A busy cell—Endoplasmic reticulum stress in the pancreatic β-cell

Keywords: Diabetes; Islet; Pancreatic β-cell; Insulin; ER stress; PERK; CHOP; eIF2α; Salubrinal; BiP/GRP78; Wolcott–Rallison syndrome; Akita mouse; IRE1α; XBP-1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line

Keywords: XBP-1; Unfolded protein response; ER stress; IGF1; Akt; Anti-apoptosis; Zebrafish;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Coordination of upregulated XBP-1 and downregulated c-myc during myeloma cell differentiation induced by 2-methoxyestradiol

Keywords: 2-Methoxyestradiol (2ME2); Differentiation; Myeloma; XBP-1; c-myc; Blimp-1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic β-cell dysfunction and insulin resistance

Keywords: Ad; adenovirus; Bip; immunoglobulin binding protein; DN; dominant-negative; eIF2α; α subunit of translation initiation factor 2; ER; endoplasmic reticulum; IRS-1; insulin receptor substrate 1; IP-1; JNK-interacting protein-1; JNK; c-Jun N-terminal kinas

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Gene expression profiling and multiple myeloma

Keywords: myeloma; MGUS; gene expression; immunoglobulin; chromosome 13; DKK-1; RAN; CHCL1; ZHX-2; unfolded protein response; XBP-1;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه