Keywords: β-adrenergic receptor; phospholamban; pathological gene program; α-MyHC; α-Myosin heavy chain; β-AR; β-Adrenergic receptor; β1-AR; β1-Adrenergic receptor; β2-AR; β2-Adrenergic receptor; Bmax; Total β-adrenergic receptor expression; GRK2; G prote
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Capillary electrophoresis in the context of drug discovery
Keywords: ACE; affinity capillary electrophoresis; AGP; α-acid glycoprotein; AH; adrenaline hydrochloride; AIμEA; automatic micro-enzyme assay; AL; amlodipine; AT; antithrombin III; Bag3; Bcl2-associated anthanogene 3; BGE; background electrolyte; CM; chylomicron
Keywords: asthma; COPD; pulmonary fibrosis; pulmonary hypertension; ADDS; antibody-dependent degranulatory synapse; ASM; airway smooth muscle; β2-AR; β2-adrenergic receptor; Ca2+; calcium ion; CADM1; cell adhesion molecule 1; CD; cluster of differentiation; CPA3;
Keywords: β2-AR; β2-adrenoreceptor; ASM; airway smooth muscle; BI; Bliss independence; COPD; chronic obstructive pulmonary disease; CRC; concentration-response curve; E; effect; EFS; electrical field stimulation; ECn; effective concentration for n% of maximal eff
Muscularis macrophages: Key players in intestinal homeostasis and disease
Keywords: MÏ; Macrophage; LpMÏ; Lamina propria macrophage; MMÏ; Muscularis macrophage; ENS; Enteric nervous system; DCs; Dendritic cells; β2-AR; Ã2-adrenergic receptors; POI; Postoperative ileus; α7nAChR; α7 nicotinic receptor; CNS; Central nervous system; I
E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes
Keywords: α-mhc; α-myosin heavy chain; β2-AR; beta-2-adrenergic receptor; Bax; Bcl2 associated protein X; Bcl2; B-cell lymphoma 2; Blm2; bloom syndrome 2 homolog; Bnip3; Bcl2 interacting protein 3; Chk1; checkpoint kinase 1; c-src; proto-oncogene tyrosine protei
Mahuannin B an adenylate cyclase inhibitor attenuates hyperhidrosis via suppressing β2-adrenoceptor/cAMP signaling pathway
Keywords: Ephedra Radix; Hyperhidrosis; Adenylate cyclase inhibitor; Mahuannin B; TCMs; traditional Chinese Medicines; EH; Ephedra Herba; ER; Ephedra Radix; APIs; active pharmacological ingredients; β2-AR; β2-adrenoceptor; AC; adenylate cyclase; cAMP; cyclic aden
Oxysterol, 5α-cholestan-3-one, modulates a contractile response to β2-adrenoceptor stimulation in the mouse atria: Involvement of NO signaling
Keywords: 5αCh3; 5α-cholestan-3-one; β2-AR; β2-adrenergic receptor; NO; nitric oxide; l-NAME; NÏ-Nitro-l-arginine methyl ester hydrochloride; PTX; pertussis toxin; Oxysterol; β2-Adrenoceptor; Contraction; Nitric oxide; Calcium; Atria;
Research paperSpecific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent β3-adrenergic signaling
Keywords: VR; visible radiation; Opn1; cone opsin; Opn2; type II opsin; β2-AR; beta-2 adrenergic receptor; β3-AR; beta-3 adrenergic receptor type 3; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; cGMP; cyclic guanosine monophosphate; PKG; protein ki
Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1
Keywords: β2-AR; β2-adrenergic receptor; CB1; type 1 cannabinoid receptor; CCM; cholesterol consensus motif; CRAC; cholesterol interaction/recognition amino acid sequence consensus; CT-B; cholera toxin subunit B; GPCR; G-protein-coupled receptor; H8; helix 8; MD;
β2-adrenergic receptor signaling promotes pancreatic ductal adenocarcinoma (PDAC) progression through facilitating PCBP2-dependent c-myc expression
Keywords: β2-AR; PCBP2; c-myc; Pancreatic cancer; Proliferation;
ReviewRegulation, Signaling, and Physiological Functions of G-Proteins
Keywords: GPCR; G-protein-coupled receptor; G-protein; guanine-nucleotide-binding regulatory proteins; β2-AR; β2-adrenergic receptor; GPR; G-protein regulator; GBA; Gα-binding and activating; RGS; regulators of G-protein signaling; RTK; receptor tyrosine kinase;
ReviewOpioid-induced hyperalgesia: Cellular and molecular mechanisms
Keywords: 5-HT; serotonin; β2-AR; β2-adrenergic receptor; β-FNA; β-funaltrexamine; BDNF; brain derived neurotrophic factor; CCK; cholecystokinin; CNS; central nervous system; CxCR; chemokine receptor; CxCL; chemokine; DAMGO; Tyr-D-Ala-Gly-NMe-Phe-Gly-ol; DOR; d
Pharmacological characterization of the interaction between the dual phosphodiesterase (PDE) 3/4 inhibitor RPL554 and glycopyrronium on human isolated bronchi and small airways
Keywords: RPL554; Glycopyrronium; Synergistic interaction; Relaxant response; Human isolated bronchi; Small airways; Airway smooth muscle; Asthma; COPD; β2-AR; β2-adrenoreceptor; ASM; airway smooth muscle; BI; Bliss independence; COPD; chronic obstructive pulmona
Insights into the conformational perturbations of novel agonists with β3-adrenergic receptor using molecular dynamics simulations
Keywords: Molecular dynamics simulation; Beta 3-adrenergic receptor; Molecular docking; DPPC; 2-dipalmitoyl-sn-phosphocholine; 3D; 3 dimensional; β1-AR; beta 1-adrenergic receptors; β2-AR; beta 2-adrenergic receptors; β3-AR; beta 3-adrenergic receptors; MD; mole
β2-AR-induced Her2 transactivation mediated by Erbin confers protection from apoptosis in cardiomyocytes
Keywords: Erbin; β2-AR; Her2; Cardiomyocyte; Apoptosis;
The three α1-adrenoceptor subtypes show different spatio-temporal mechanisms of internalization and ERK1/2 phosphorylation
Keywords: α1-AR; α1 adrenoceptor; β2-AR; β2 adrenoceptor; AT1AR; angiotensin receptor type 1A; Bmax; maximum number of binding sites; BSA; bovine serum albumin; ConA; concanavalin A; DMSO; dimethyl sulfoxide; EGFR; epidermal growth factor receptor; GAPDH; glyce
The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner
Keywords: AC; adenylyl cyclase; Bmax; maximal binding capacity; BSA; bovine serum albumin; β2-AR; β2-adrenergic receptor; CA; [3H]-cAMP formed; CT; cytoplasmic tail; DA; dopamine; DMSO; dimethyl sulfoxide; EL3; third extracellular loop; EC50; effective concentrat
Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β2-adrenergic receptor
Keywords: β2-AR; β2-adrenergic receptor; Bmax; Binding maximum of the ligand for the receptor; COS-1; Monkey kidney cells; GPCRs; G protein-coupled receptors; HEK293; human embryonic kidney cells; [3H] DHA; tritium labeled dihydroalprenolol; Kd; equilibrium disso
Airway remodeling contributes to the progressive loss of lung function in asthma: An overview
Keywords: Asthma; airway; remodeling; inflammation; AHR; Airways hyperresponsiveness; ASM; Airway smooth muscle; β2-AR; β2-Adrenergic receptor; MUC; Mucin glycoprotein; RBM; Reticular basement membrane; STAT; Signal transducer and activator of transcription; VEGF
The cardiac β2-adrenergic signalling a new role for the cPLA2
Keywords: β-AR; β-adrenergic receptor; G protein; guanine nucleotide binding protein; PTX; pertussis toxin; AC; adenylyl cyclase; tAC; transmembraneous adenylyl cyclase; sAC; soluble adenylyl cyclase; cPLA2; cytosolic phospholipase A2; sPLA2; secreted phospholipa