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Daneshyari Ageing Journas Latest Articles

Ageing Research Articles

Selenium and GPX4, a vital symbiosis
Fulltext Access 28 Pages 2018
NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells
Fulltext Access 28 Pages 2018
Mild ozonisation activates antioxidant cell response by the Keap1/Nrf2 dependent pathway
Fulltext Access 28 Pages 2018
Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells
Fulltext Access 28 Pages 2018
Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface
Fulltext Access 28 Pages 2018
Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation
Fulltext Access 28 Pages 2018
Keto-enol-based modification on piperlongumine to generate a potent Cu(II) ionophore that triggers redox imbalance and death of HepG2 cells
Fulltext Access 28 Pages 2018
An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice
Fulltext Access 28 Pages 2018
Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome
Fulltext Access 28 Pages 2018
Flow cytometric HyPer-based assay for hydrogen peroxide
Fulltext Access 28 Pages 2018
FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity
Fulltext Access 28 Pages 2018
Detection of the formyl radical by EPR spin-trapping and mass spectrometry
Fulltext Access 28 Pages 2018
On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease
Fulltext Access 29 Pages 2018
Redox and the circadian clock in plant immunity: A balancing act
Fulltext Access 29 Pages 2018
Expression of the gene coading for PGC-1α in peripheral blood leukocytes and related gene variants in patients with Parkinson's disease
Fulltext Access 29 Pages 2018
PIWI-piRNA pathway: Setting the pace of aging by reducing DNA damage
Fulltext Access 29 Pages 2018
Back to the future: Epigenetic clock plasticity towards healthy aging
Fulltext Access 29 Pages 2018
HIV antiretroviral therapy drugs induce premature senescence and altered physiology in HUVECs
Fulltext Access 29 Pages 2018
The effect of ARC ablation on skeletal muscle morphology, function, and apoptotic signaling during aging
Fulltext Access 29 Pages 2018
Crosstalk between Nrf2 and YAP contributes to maintaining the antioxidant potential and chemoresistance in bladder cancer
Fulltext Access 29 Pages 2018
Resting state fMRI studies in SPG4-linked hereditary spastic paraplegia
Fulltext Access 29 Pages 2018
Neuropathic pain and SCI: Identification and treatment strategies in the 21st century
Fulltext Access 29 Pages 2018
S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia
Fulltext Access 29 Pages 2018
Erythrocyte SOD1 activity, but not SOD1 polymorphisms, is associated with ICU mortality in patients with septic shock
Fulltext Access 29 Pages 2018
Identification of a prospective early motor progression cluster of Parkinson's disease: Data from the PPMI study
Fulltext Access 29 Pages 2018
DCTN1 F52L mutation case of Perry syndrome with progressive supranuclear palsy-like tauopathy
Fulltext Access 29 Pages 2018
Walking disability measures in multiple sclerosis patients: Correlations with MRI-derived global and microstructural damage
Fulltext Access 29 Pages 2018
Telomere length alterations in microsatellite stable colorectal cancer and association with the immune response
Fulltext Access 29 Pages 2018
A bell-shaped dependence between amyloidosis and GABA accumulation in astrocytes in a mouse model of Alzheimer's disease
Fulltext Access 29 Pages 2018
TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells
Fulltext Access 29 Pages 2018
ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice
Fulltext Access 29 Pages 2018
Redox-sensitive signaling in inflammatory T cells and in autoimmune disease
Fulltext Access 29 Pages 2018
Differential diagnosis of parkinsonian syndromes using dopamine transporter and perfusion SPECT
Fulltext Access 29 Pages 2018
Multimodal neuroimaging and behavioral assessment of α-synuclein polymorphism rs356219 in older adults
Fulltext Access 29 Pages 2018
Prolactin regulatory element-binding (PREB) protein regulates hepatic glucose homeostasis
Fulltext Access 29 Pages 2018
Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis
Fulltext Access 30 Pages 2018
Inhibition of cathepsin L alleviates the microglia-mediated neuroinflammatory responses through caspase-8 and NF-κB pathways
Fulltext Access 30 Pages 2018
Expression of reactive species related genes is associated with patient survival in luminal B breast cancer
Fulltext Access 30 Pages 2018
Postmortem MRI and histology demonstrate differential iron accumulation and cortical myelin organization in early- and late-onset Alzheimer's disease
Fulltext Access 30 Pages 2018
Kinetic and stoichiometric constraints determine the pathway of H2O2 consumption by red blood cells
Fulltext Access 30 Pages 2018
Selenoprotein T is a key player in ER proteostasis, endocrine homeostasis and neuroprotection
Fulltext Access 30 Pages 2018
Long-lived and short-lived reactive species produced by a cold atmospheric pressure plasma jet for the inactivation of Pseudomonas aeruginosa and Staphylococcus aureus
Fulltext Access 30 Pages 2018
mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia
Fulltext Access 30 Pages 2018
MR findings in the substantia nigra on phase difference enhanced imaging in neurodegenerative parkinsonism
Fulltext Access 30 Pages 2018
A new bioluminescent imaging technology for studying oxidative stress in the testis and its impacts on fertility
Fulltext Access 30 Pages 2018
Epigenome dysregulation in cholangiocarcinoma
Fulltext Access 30 Pages 2018
Aging and nutrition induce tissue-specific changes on global DNA methylation status in rats
Fulltext Access 30 Pages 2018
Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease
Fulltext Access 30 Pages 2018
GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation
Fulltext Access 30 Pages 2018
Depletion of Ubiquilin induces an augmentation in soluble ubiquitinated Drosophila TDP-43 to drive neurotoxicity in the fly
Fulltext Access 30 Pages 2018
Nox4 in renal diseases: An update
Fulltext Access 30 Pages 2018
Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk
Fulltext Access 30 Pages 2018
Insulin resistance and cognitive test performance in elderly adults: National health and nutrition examination survey (NHANES)
Fulltext Access 31 Pages 2018
Correlation between serum uric acid and diabetic peripheral neuropathy in T2DM patients
Fulltext Access 31 Pages 2018
An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma
Fulltext Access 31 Pages 2018
Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging
Fulltext Access 31 Pages 2018
Artesunate-induced mitophagy alters cellular redox status
Fulltext Access 31 Pages 2018
Evolution, regulation, and function of porcine selenogenome
Fulltext Access 31 Pages 2018
The ATF6α arm of the Unfolded Protein Response mediates replicative senescence in human fibroblasts through a COX2/prostaglandin E2 intracrine pathway
Fulltext Access 31 Pages 2018
Genetic and functional characters of GRN p.T487I mutation in Taiwanese patients with atypical parkinsonian disorders
Fulltext Access 31 Pages 2018
Vitamin D receptor (VDR) gene polymorphism and vascular dementia due to cerebral small vessel disease in an Asian Indian cohort
Fulltext Access 31 Pages 2018
Distinction between anti-VGKC-complex seropositive patients with and without anti-LGI1/CASPR2 antibodies
Fulltext Access 31 Pages 2018
Association analyses of variants of SIPA1L2, MIR4697, GCH1, VPS13C, and DDRGK1 with Parkinson's disease in East Asians
Fulltext Access 31 Pages 2018
Age-related defects in short-term plasticity are reversed by acetyl-L-carnitine at the mouse calyx of Held
Fulltext Access 31 Pages 2018
GLP-1 receptor agonists and reduction of cardiometabolic risk: Potential underlying mechanisms
Fulltext Access 31 Pages 2018
A new evaluation of masticatory ability in patients with dysphagia: The Saku-Saku Test
Fulltext Access 31 Pages 2018
Structure and energetic basis of overrepresented λ light chain in systemic light chain amyloidosis patients
Fulltext Access 31 Pages 2018
Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up
Fulltext Access 31 Pages 2018
VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function
Fulltext Access 31 Pages 2018
Orai1 is critical for Notch-driven aggressiveness under hypoxic conditions in triple-negative breast cancers
Fulltext Access 31 Pages 2018
HSF1, in association with MORC2, downregulates ArgBP2 via the PRC2 family in gastric cancer cells
Fulltext Access 31 Pages 2018
Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts
Fulltext Access 31 Pages 2018
TGF-β synergizes with ML264 to block IL-1β-induced matrix degradation mediated by Krüppel-like factor 5 in the nucleus pulposus
Fulltext Access 31 Pages 2018
Rotavirus-encoded virus-like small RNA triggers autophagy by targeting IGF1R via the PI3K/Akt/mTOR pathway
Fulltext Access 31 Pages 2018
The physical capabilities underlying timed “Up and Go” test are time-dependent in community-dwelling older women
Fulltext Access 31 Pages 2018
Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria
Fulltext Access 31 Pages 2018
Use of LC-MS for the quantitative analysis of (poly)phenol metabolites does not necessarily yield accurate results: Implications for assessing existing data and conducting future research
Fulltext Access 31 Pages 2018
Electron transfer kinetics of the mitochondrial outer membrane protein mitoNEET
Fulltext Access 31 Pages 2018
Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes
Fulltext Access 31 Pages 2018
Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway
Fulltext Access 31 Pages 2018
The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease
Fulltext Access 31 Pages 2018
Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic
Fulltext Access 32 Pages 2018
Isoprenoids and tau pathology in sporadic Alzheimer's disease
Fulltext Access 32 Pages 2018
Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity
Fulltext Access 32 Pages 2018
Longitudinal serum S100β and brain aging in the Lothian Birth Cohort 1936
Fulltext Access 32 Pages 2018
Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis
Fulltext Access 32 Pages 2018
High frequency of C9orf72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis patients from two founder populations sharing the same risk haplotype
Fulltext Access 32 Pages 2018
Family ties and functional limitation in the elderly: Results from the Survey of Health Ageing and Retirement in Europe (SHARE)
Fulltext Access 32 Pages 2018
Blockade of TREM-1 prevents vitreoretinal neovascularization in mice with oxygen-induced retinopathy
Fulltext Access 32 Pages 2018
Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease
Fulltext Access 32 Pages 2018
The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats
Fulltext Access 32 Pages 2018
Hyperhomocysteinemia potentiates diabetes-impaired EDHF-induced vascular relaxation: Role of insufficient hydrogen sulfide
Fulltext Access 32 Pages 2018
HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production
Fulltext Access 32 Pages 2018
Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver
Fulltext Access 32 Pages 2018
TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4
Fulltext Access 32 Pages 2018
Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma
Fulltext Access 32 Pages 2018
The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma
Fulltext Access 32 Pages 2018
The scavenger activity of the human P2X7 receptor differs from P2X7 pore function by insensitivity to antagonists, genetic variation and sodium concentration: Relevance to inflammatory brain diseases
Fulltext Access 32 Pages 2018
Hypothermia augments stress response in mammalian cells
Fulltext Access 32 Pages 2018
From Snow to Hill to ALS: An epidemiological odyssey in search of ALS causation
Fulltext Access 32 Pages 2018
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