ANKRD9 is associated with tumor suppression as a substrate receptor subunit of ubiquitin ligase Fulltext Access 32 Pages 2018
Oral pioglitazone ameliorates fructose-induced peripheral insulin resistance and hippocampal gliosis but not restores inhibited hippocampal adult neurogenesis Fulltext Access 32 Pages 2018
Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression Fulltext Access 32 Pages 2018
SIRT1 regulates inflammation response of macrophages in sepsis mediated by long noncoding RNA Fulltext Access 32 Pages 2018
Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells Fulltext Access 33 Pages 2018
Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy Fulltext Access 33 Pages 2018
Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation Fulltext Access 33 Pages 2018
Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy Fulltext Access 33 Pages 2018
Epigenetic and non-epigenetic functions of the RYBP protein in development and disease Fulltext Access 33 Pages 2018
Deep brain stimulation is effective in pediatric patients with GNAO1 associated severe hyperkinesia Fulltext Access 33 Pages 2018
PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p Fulltext Access 33 Pages 2018
N-acetyl cysteine reverts the proinflammatory state induced by cigarette smoke extract in lung Calu-3 cells Fulltext Access 33 Pages 2018
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways Fulltext Access 33 Pages 2018
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats Fulltext Access 33 Pages 2018
Hepatic oxidative stress in pigmented P23H rhodopsin transgenic rats with progressive retinal degeneration Fulltext Access 33 Pages 2018
Glycine Transporter-1 and glycine receptor mediate the antioxidant effect of glycine in diabetic rat islets and INS-1 cells Fulltext Access 33 Pages 2018
Metformin overcomes high glucose-induced insulin resistance of podocytes by pleiotropic effects on SIRT1 and AMPK Fulltext Access 33 Pages 2018
The SGK1 inhibitor EMD638683, prevents Angiotensin II-induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation Fulltext Access 33 Pages 2018
Aβ dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease Fulltext Access 33 Pages 2018
The temporal sequence of improved mitochondrial function on the dynamics of respiration, mobility, and cognition in aged Drosophila Fulltext Access 33 Pages 2018
Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration Fulltext Access 33 Pages 2018
MicroRNA alterations in iPSC-derived dopaminergic neurons from Parkinson disease patients Fulltext Access 33 Pages 2018
Cognition or genetics? Predicting Alzheimer's disease with practice effects, APOE genotype, and brain metabolism Fulltext Access 33 Pages 2018
The retina as a window to early dysfunctions of Alzheimer's disease following studies with a 5xFAD mouse model Fulltext Access 33 Pages 2018
Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol Fulltext Access 33 Pages 2018
Adipose tissue derived-factors impaired pancreatic β-cell function in diabetes Fulltext Access 33 Pages 2018
More to NAD+ than meets the eye: A regulator of metabolic pools and gene expression in Arabidopsis Fulltext Access 33 Pages 2018
Quantitative EEG power and synchronization correlate with Alzheimer's disease CSF biomarkers Fulltext Access 33 Pages 2018
A certain role of SOD/CAT imbalance in pathogenesis of autism spectrum disorders Fulltext Access 34 Pages 2018
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease Fulltext Access 34 Pages 2018
Phosphorylation of SET mediates apoptosis via P53 hyperactivation and NM23-H1 nuclear import Fulltext Access 34 Pages 2018
Induction of REDD1 via AP-1 prevents oxidative stress-mediated injury in hepatocytes Fulltext Access 34 Pages 2018
Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway Fulltext Access 34 Pages 2018
Feasibility, safety, acceptability, and functional outcomes of playing Nintendo Wii Fit PlusTM for frail older adults: A randomized feasibility clinical trial Fulltext Access 34 Pages 2018
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent Fulltext Access 34 Pages 2018
TRF1 as a major contributor for telomeres' shortening in the context of obesity Fulltext Access 34 Pages 2018
Dopamine-dependent cognitive processes after menopause: the relationship between COMT genotype, estradiol, and working memory Fulltext Access 34 Pages 2018
Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice Fulltext Access 34 Pages 2018
IL-23 production of liver inflammatory macrophages to damaged hepatocytes promotes hepatocellular carcinoma development after chronic hepatitis B virus infection Fulltext Access 34 Pages 2018
Overexpression of CXCR4 synergizes with LL-37 in the metastasis of breast cancer cells Fulltext Access 34 Pages 2018
Amyloid-β-related and unrelated cortical thinning in dementia with Lewy bodies Fulltext Access 34 Pages 2018
Cross-pathway control gene CPC1/GCN4 coordinates with histone acetyltransferase GCN5 to regulate catalase-3 expression under oxidative stress in Neurospora crassa Fulltext Access 34 Pages 2018
AMP-activated protein kinase sparks the fire of cardioprotection against myocardial ischemia and cardiac ageing Fulltext Access 34 Pages 2018
Endothelial cells cope with hypoxia-induced depletion of ATP via activation of cellular purine turnover and phosphotransfer networks Fulltext Access 34 Pages 2018
HER4 promotes cell survival and chemoresistance in osteosarcoma via interaction with NDRG1 Fulltext Access 34 Pages 2018
Cortical β-amyloid burden, gray matter, and memory in adults at varying APOE ε4 risk for Alzheimer's disease Fulltext Access 34 Pages 2018
The U2AF homology motif kinase 1 (UHMK1) is upregulated upon hematopoietic cell differentiation Fulltext Access 34 Pages 2018
Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake Fulltext Access 34 Pages 2018
APOE ε4 status in healthy older African Americans is associated with deficits in pattern separation and hippocampal hyperactivation Fulltext Access 34 Pages 2018
Motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of NADPH oxidase, CAMKII, and PKC at preplaque stage in the TgCRND8 mouse model of Alzheimer's disease Fulltext Access 34 Pages 2018
Connecting chaperone-mediated autophagy dysfunction to cellular senescence Fulltext Access 35 Pages 2018
TRAIL protects against endothelial dysfunction in vivo and inhibits angiotensin-II-induced oxidative stress in vascular endothelial cells in vitro Fulltext Access 35 Pages 2018
FGF binding proteins (FGFBPs): Modulators of FGF signaling in the developing, adult, and stressed nervous system Fulltext Access 35 Pages 2018
Identification of homocysteine-suppressive mitochondrial ETC complex genes and tissue expression profile - Novel hypothesis establishment Fulltext Access 35 Pages 2018
Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells Fulltext Access 35 Pages 2018
Multimodal MRI quantification of the common neurostructural bases within the FTD-ALS continuum Fulltext Access 35 Pages 2018
Pigment epithelium derived factor regulates human Sost/Sclerostin and other osteocyte gene expression via the receptor and induction of Erk/GSK-3beta/beta-catenin signaling Fulltext Access 35 Pages 2018
The phosphorylated redox proteome of Chlamydomonas reinhardtii: Revealing novel means for regulation of protein structure and function Fulltext Access 35 Pages 2018
Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain Fulltext Access 35 Pages 2018
n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD Fulltext Access 35 Pages 2018
Repression of adenosine triphosphate-binding cassette transporter ABCG2 by estrogen increases intracellular glutathione in brain endothelial cells following ischemic reperfusion injury Fulltext Access 35 Pages 2018
Beta-sheet assembly of Tau and neurodegeneration in Drosophila melanogaster Fulltext Access 35 Pages 2018
A novel S-nitrosocaptopril monohydrate for pulmonary arterial hypertension: H2O and -SNO intermolecular stabilization chemistry Fulltext Access 35 Pages 2018
Long-term effects of prolonged-release fampridine in cognitive function, fatigue, mood and quality of life of MS patients: The IGNITE study Fulltext Access 35 Pages 2018
EEG-based neurophysiological indicators of hallucinations in Alzheimer's disease: Comparison with dementia with Lewy bodies Fulltext Access 35 Pages 2018
Baroreflex sensitivity and heart rate variability are predictors of mortality in patients with aneurysmal subarachnoid haemorrhage Fulltext Access 35 Pages 2018
Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport Fulltext Access 35 Pages 2018
New perspectives for pharmacological chaperoning treatment in methylmalonic aciduria cblB type Fulltext Access 35 Pages 2018
C-terminal oligomerization of podocin mediates interallelic interactions Fulltext Access 35 Pages 2018
Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes Fulltext Access 35 Pages 2018
Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditis Fulltext Access 35 Pages 2018
Inhibition of EGFR attenuates fibrosis and stellate cell activation in diet-induced model of nonalcoholic fatty liver disease Fulltext Access 35 Pages 2018
IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p Fulltext Access 35 Pages 2018
Simvastatin blocks soluble SSAO/VAP-1 release in experimental models of cerebral ischemia: Possible benefits for stroke-induced inflammation control Fulltext Access 35 Pages 2018
Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of hOGG1 through small molecule intervention Fulltext Access 35 Pages 2018
miR-146a regulates inflammatory cytokine production in Porphyromonas gingivalis lipopolysaccharide-stimulated B cells by targeting IRAK1 but not TRAF6 Fulltext Access 35 Pages 2018
Shades of white: diffusion properties of T1- and FLAIR-defined white matter signal abnormalities differ in stages from cognitively normal to dementia Fulltext Access 36 Pages 2018
Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans Fulltext Access 36 Pages 2018
High glucose forces a positive feedback loop connecting ErbB4 expression and mTOR/S6K pathway to aggravate the formation of tau hyperphosphorylation in differentiated SH-SY5Y cells Fulltext Access 36 Pages 2018
Regulatory crosstalk between KLF5, miR-29a and Fbw7/CDC4 cooperatively promotes atherosclerotic development Fulltext Access 36 Pages 2018
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking Fulltext Access 36 Pages 2018
Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice Fulltext Access 36 Pages 2018
Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis Fulltext Access 36 Pages 2018
A distinct class of antioxidant response elements is consistently activated in tumors with NRF2 mutations Fulltext Access 36 Pages 2018
Genetic determinants of cholangiopathies: Molecular and systems genetics Fulltext Access 36 Pages 2018
Nuclear receptor FXR, bile acids and liver damage: Introducing the progressive familial intrahepatic cholestasis with FXR mutations Fulltext Access 36 Pages 2018
BMP signaling-driven osteogenesis is critically dependent on Prdx-1 expression-mediated maintenance of chondrocyte prehypetrophy Fulltext Access 36 Pages 2018
RNF185 modulates JWA ubiquitination and promotes gastric cancer metastasis Fulltext Access 36 Pages 2018
LAZ3 protects cardiac remodeling in diabetic cardiomyopathy via regulating miR-21/PPARa signaling Fulltext Access 36 Pages 2018
The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis Fulltext Access 36 Pages 2018
Calmodulin and IQGAP1 activation of PI3Kα and Akt in KRAS, HRAS and NRAS-driven cancers Fulltext Access 36 Pages 2018
Ticagrelor for stroke prevention in patients with vascular risk factors: A systematic review and meta-analysis Fulltext Access 36 Pages 2018
Hyperglycemia predicts unfavorable outcomes in acute ischemic stroke patients treated with intravenous thrombolysis among a Chinese population: A prospective cohort study Fulltext Access 36 Pages 2018