Metabolites from invasive pests inhibit mitochondrial complex II: A potential strategy for the treatment of human ovarian carcinoma? Fulltext Access 6 Pages 2016
Crystal structure of methylesterase family member 16 (MES16) from Arabidopsis thaliana Fulltext Access 6 Pages 2016
A negative-feedback loop regulating ERK1/2 activation and mediated by RasGPR2 phosphorylation Fulltext Access 6 Pages 2016
Geraniol improves endothelial function by inhibiting NOX-2 derived oxidative stress in high fat diet fed mice Fulltext Access 6 Pages 2016
Orai1 mediates osteogenic differentiation via BMP signaling pathway in bone marrow mesenchymal stem cells Fulltext Access 6 Pages 2016
Transient exposure to proteins SOX2, Oct-4, and NANOG immortalizes exhausted tumor-infiltrating CTLs Fulltext Access 6 Pages 2016
Mycobacterium tuberculosis EIS gene inhibits macrophage autophagy through up-regulation of IL-10 by increasing the acetylation of histone H3 Fulltext Access 6 Pages 2016
Stk1-mediated phosphorylation stimulates the DNA-binding properties of the Staphylococcus aureus SpoVG transcriptional factor Fulltext Access 6 Pages 2016
TLR4 induces CREB-mediated IL-6 production via upregulation of F-spondin to promote vascular smooth muscle cell migration Fulltext Access 6 Pages 2016
A novel CRE recombinase assay for quantification of GAL10-non coding RNA suppression on transcriptional leakage Fulltext Access 6 Pages 2016
Exploring the membrane fusion mechanism through force-induced disassembly of HIV-1 six-helix bundle Fulltext Access 6 Pages 2016
Non-native ligands define the active site of Pennisetum glaucum (L.) R. Br dehydroascorbate reductase Fulltext Access 6 Pages 2016
Functional impairment of endothelial cells by the antimycotic amphotericin B Fulltext Access 6 Pages 2016
Pramipexole pretreatment attenuates myocardial ischemia/reperfusion injury through upregulation of autophagy Fulltext Access 6 Pages 2016
Isolation of endosulfan sulfate-degrading Rhodococcus koreensis strain S1-1 from endosulfan contaminated soil and identification of a novel metabolite, endosulfan diol monosulfate Fulltext Access 6 Pages 2016
Aberrant localization of lamin B receptor (LBR) in cellular senescence in human cells Fulltext Access 6 Pages 2016
HSP-1/2, a major horse seminal plasma protein, acts as a chaperone against oxidative stress Fulltext Access 6 Pages 2016
PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant Fulltext Access 6 Pages 2016
Methionine sulfoxide reductase B3 deficiency stimulates heme oxygenase-1 expression via ROS-dependent and Nrf2 activation pathways Fulltext Access 6 Pages 2016
Light induces translocation of NF-κB p65 to the mitochondria and suppresses expression of cytochrome c oxidase subunit III (COX III) in the rat retina Fulltext Access 6 Pages 2016
Overexpression of Dyrk1A regulates cardiac troponin T splicing in cells and mice Fulltext Access 6 Pages 2016
PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells Fulltext Access 6 Pages 2016
Exercise-induced increase in IL-6 level enhances GLUT4 expression and insulin sensitivity in mouse skeletal muscle Fulltext Access 6 Pages 2016
Superior angiogenesis facilitates digit regrowth in MRL/MpJ mice compared to C57BL/6 mice Fulltext Access 6 Pages 2016
Collagencin, an antibacterial peptide from fish collagen: Activity, structure and interaction dynamics with membrane Fulltext Access 6 Pages 2016
GSE1 negative regulation by miR-489-5p promotes breast cancer cell proliferation and invasion Fulltext Access 6 Pages 2016
Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer Fulltext Access 6 Pages 2016
The solution structure of the kallikrein-related peptidases inhibitor SPINK6 Fulltext Access 6 Pages 2016
Group IVA phospholipase A2 deficiency prevents CCl4-induced hepatic cell death through the enhancement of autophagy Fulltext Access 6 Pages 2016
The small molecule survivin inhibitor YM155 may be an effective treatment modality for colon cancer through increasing apoptosis Fulltext Access 6 Pages 2016
Homocysteine upregulates hepcidin expression through BMP6/SMAD signaling pathway in hepatocytes Fulltext Access 6 Pages 2016
Fenofibrate inhibited pancreatic cancer cells proliferation via activation of p53 mediated by upregulation of LncRNA MEG3 Fulltext Access 6 Pages 2016
Identification and characterization of the RNA-binding protein Rbfox3 in zebrafish embryo Fulltext Access 6 Pages 2016
Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation Fulltext Access 6 Pages 2016
Pyrithione Zn selectively inhibits hypoxia-inducible factor prolyl hydroxylase PHD3 Fulltext Access 6 Pages 2016
The prion protein selectively binds to and modulates the content of purinergic receptor P2X4R Fulltext Access 6 Pages 2016
DDX21 translocates from nucleus to cytoplasm and stimulates the innate immune response due to dengue virus infection Fulltext Access 6 Pages 2016
Sequential hydroxylation of vitamin D2 by a genetically engineered CYP105A1 Fulltext Access 6 Pages 2016
Conformation switching of AIM2 PYD domain revealed by NMR relaxation and MD simulation Fulltext Access 6 Pages 2016
Sphingosine inhibits the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) activity Fulltext Access 6 Pages 2016
Proteomic profile of hemolymph and detection of induced antimicrobial peptides in response to microbial challenge in Diatraea saccharalis (Lepidoptera: Crambidae) Fulltext Access 6 Pages 2016
Crystal structure of the Bacillus-conserved MazG protein, a nucleotide pyrophosphohydrolase Fulltext Access 6 Pages 2016
Human dehydrogenase/reductase (SDR family) member 11 is a novel type of 17β-hydroxysteroid dehydrogenase Fulltext Access 6 Pages 2016
Gene expression profiling reveals Nef induced deregulation of lipid metabolism in HIV-1 infected T cells Fulltext Access 6 Pages 2016
Astragalus polysaccharide upregulates hepcidin and reduces iron overload in mice via activation of p38 mitogen-activated protein kinase Fulltext Access 6 Pages 2016
TGF-β regulates TGFBIp expression in corneal fibroblasts via miR-21, miR-181a, and Smad signaling Fulltext Access 6 Pages 2016
c-Jun N-terminal kinase regulates the nucleoplasmic translocation and stability of nucleolar GLTSCR2 protein Fulltext Access 6 Pages 2016
The properties of the actin-myosin interaction in the heart muscle depend on the isoforms of myosin but not of α-actin Fulltext Access 6 Pages 2016
Smurf1 represses TNF-α production through ubiquitination and destabilization of USP5 Fulltext Access 6 Pages 2016
The interaction domains of transient receptor potential canonical (TRPC)1/4 and TRPC1/5 heteromultimeric channels Fulltext Access 6 Pages 2016
Complementary role of CNNM2 in sperm motility and Ca2+ influx during capacitation Fulltext Access 6 Pages 2016
ERRF is essential for Estrogen-Estrogen Receptor alpha signaling pathway in ER positive breast cancer cells Fulltext Access 6 Pages 2016
FXR blocks the growth of liver cancer cells through inhibiting mTOR-s6K pathway Fulltext Access 6 Pages 2016
Anti-inflammatory activity of chloroquine and amodiaquine through p21-mediated suppression of T cell proliferation and Th1 cell differentiation Fulltext Access 6 Pages 2016
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma Fulltext Access 6 Pages 2016
High glucose-induced Matrilin-2 expression in mouse mesangial cells was mediated by transforming growth factor beta 1 (TGF-β1) Fulltext Access 6 Pages 2016
The transcription factor SlDof22 involved in ascorbate accumulation and salinity stress in tomato Fulltext Access 6 Pages 2016
A comparative structural analysis reveals distinctive features of co-factor binding and substrate specificity in plant aldo-keto reductases Fulltext Access 6 Pages 2016
Nek11 regulates asymmetric cell division during mouse oocyte meiotic maturation Fulltext Access 6 Pages 2016
Role of ATF5 in the invasive potential of diverse human cancer cell lines Fulltext Access 6 Pages 2016
Drp1 guarding of the mitochondrial network is important for glucose-stimulated insulin secretion in pancreatic beta cells Fulltext Access 6 Pages 2016
High mobility group protein DSP1 negatively regulates HSP70 transcription in Crassostrea hongkongensis Fulltext Access 6 Pages 2016
Acetylshikonin from Zicao exerts antifertility effects at high dose in rats by suppressing the secretion of GTH Fulltext Access 6 Pages 2016
Increased copper toxicity in Saccharomyces cerevisiae lacking VPS35, a component of the retromer and monogenic Parkinson disease gene in humans Fulltext Access 6 Pages 2016
Characterization of rabbit limbal epithelial side population cells using RNA sequencing and single-cell qRT-PCR Fulltext Access 6 Pages 2016
Adipocyte insulin receptor activity maintains adipose tissue mass and lifespan Fulltext Access 6 Pages 2016
TGF-β1 accelerates the DNA damage response in epithelial cells via Smad signaling Fulltext Access 6 Pages 2016
Tyrosine binding and promiscuity in the arginine repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis Fulltext Access 6 Pages 2016
A nonsense mutation of Stim1 identified in stroke-prone spontaneously hypertensive rats decreased the store-operated calcium entry in astrocytes Fulltext Access 6 Pages 2016
Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces cardiac fibroblast proliferation by suppressing GATA Binding Protein 4 Fulltext Access 6 Pages 2016
Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells Fulltext Access 6 Pages 2016
Combined pressure and temperature denaturation of ribonuclease A produces alternate denatured states Fulltext Access 6 Pages 2016
Emamectin is a non-selective allosteric activator of nicotinic acetylcholine receptors and GABAA/C receptors Fulltext Access 6 Pages 2016
Imiquimod induces ER stress and Ca2+ influx independently of TLR7 and TLR8 Fulltext Access 6 Pages 2016
Phyhd1, an XPhyH-like homologue, is induced in mouse T cells upon T cell stimulation Fulltext Access 6 Pages 2016
The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux Fulltext Access 6 Pages 2016
Transforming growth factor-β1 induces cell cycle arrest by activating atypical cyclin-dependent kinase 5 through up-regulation of Smad3-dependent p35 expression in human MCF10A mammary epithelial cells Fulltext Access 6 Pages 2016
The systemic effects of sclerostin overexpression using ΦC31 integrase in mice Fulltext Access 6 Pages 2016
Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells Fulltext Access 6 Pages 2016
Structural characterizations of phage antitoxin Dmd and its interactions with bacterial toxin RnlA Fulltext Access 6 Pages 2016
Genetic deletion of Rab27B in pancreatic acinar cells affects granules size and has inhibitory effects on amylase secretion Fulltext Access 6 Pages 2016
TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro Fulltext Access 6 Pages 2016
Forced expression of Hnf4a induces hepatic gene activation through directed differentiation Fulltext Access 6 Pages 2016
Amphipathic polyproline peptides stimulate cholesterol efflux by the ABCA1 transporter Fulltext Access 6 Pages 2016
Qualitative and quantitative estimation of comprehensive synaptic connectivity in short- and long-term cultured rat hippocampal neurons with new analytical methods inspired by Scatchard and Hill plots Fulltext Access 6 Pages 2016
Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice Fulltext Access 6 Pages 2016
AKT-p53 axis protect cancer cells from autophagic cell death during nutrition deprivation Fulltext Access 6 Pages 2016
Autophagy induction in tobacco leaves infected by potato virus YO and its putative roles Fulltext Access 6 Pages 2016
PPARγ suppresses the proliferation of cardiac myxoma cells through downregulation of MEF2D in a miR-122-dependent manner Fulltext Access 6 Pages 2016
High-fat diet-dependent modulation of the delayed rectifier K+ current in adult guinea pig atrial myocytes Fulltext Access 6 Pages 2016
Structural basis for recognition of a kink-turn motif by an archaeal homologue of human RNase P protein Rpp38 Fulltext Access 6 Pages 2016
Structural and biochemical characterization of the Bacillus cereus 3-hydroxyisobutyrate dehydrogenase Fulltext Access 6 Pages 2016