A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors Fulltext Access 7 Pages 2015
2-Deoxyglucose induces the expression of thioredoxin interacting protein (TXNIP) by increasing O-GlcNAcylation - Implications for targeting the Warburg effect in cancer cells Fulltext Access 7 Pages 2015
Dietary obacunone supplementation stimulates muscle hypertrophy, and suppresses hyperglycemia and obesity through the TGR5 and PPARγ pathway Fulltext Access 7 Pages 2015
PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma Fulltext Access 7 Pages 2015
Characterization of novel mechanisms for steatosis from global protein hyperacetylation in ethanol-induced mouse hepatocytes Fulltext Access 7 Pages 2015
CCR7 is involved in BCR-ABL/STAP-2-mediated cell growth in hematopoietic Ba/F3 cells Fulltext Access 7 Pages 2015
In vivo cardiac glucose metabolism in the high-fat fed mouse: Comparison of euglycemic-hyperinsulinemic clamp derived measures of glucose uptake with a dynamic metabolomic flux profiling approach Fulltext Access 7 Pages 2015
9-cis-retinoic acid improves sensitivity to platelet-derived growth factor-BB via RXRα and SHP-1 in diabetic retinopathy Fulltext Access 7 Pages 2015
Arabidopsis RING E3 ubiquitin ligase AtATL80 is negatively involved in phosphate mobilization and cold stress response in sufficient phosphate growth conditions Fulltext Access 7 Pages 2015
Comparative analysis of DNA methylation changes in two rice genotypes under salt stress and subsequent recovery Fulltext Access 7 Pages 2015
Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins Fulltext Access 7 Pages 2015
RLIP76-dependent suppression of PI3K/AKT/Bcl-2 pathway by miR-101 induces apoptosis in prostate cancer Fulltext Access 7 Pages 2015
Structural characterization of dioicin 1 from Phytolacca dioica L. gains novel insights into phylogenetic relationships of Phytolaccaceae type 1 RIPs Fulltext Access 7 Pages 2015
Innate immune evasion by hepatitis B virus-mediated downregulation of TRIF Fulltext Access 7 Pages 2015
Selection and characterization of human PCSK9 antibody from phage displayed antibody library Fulltext Access 7 Pages 2015
The autophagy molecule Beclin 1 maintains persistent activity of NF-κB and Stat3 in HTLV-1-transformed T lymphocytes Fulltext Access 7 Pages 2015
The Sirt1 activator SRT1720 attenuates angiotensin II-induced atherosclerosis in apoEâ/â mice through inhibiting vascular inflammatory response Fulltext Access 7 Pages 2015
Analysis of the subcellular localization of the human histone methyltransferase SETDB1 Fulltext Access 7 Pages 2015
Lenalidomide, an anti-tumor drug, regulates retinal endothelial cell function: Implication for treating ocular neovascular disorder Fulltext Access 7 Pages 2015
Mitogen activated protein kinase pathway-dependent effects of platelet-derived growth factor on migration of trophectoderm cells Fulltext Access 7 Pages 2015
Sub-chronic administration of LY294002 sensitizes cervical cancer cells to chemotherapy by enhancing mitochondrial JNK signaling Fulltext Access 7 Pages 2015
Drosophila p24 and Sec22 regulate Wingless trafficking in the early secretory pathway Fulltext Access 7 Pages 2015
miR-503 suppresses tumor cell proliferation and metastasis by directly targeting RNF31 in prostate cancer Fulltext Access 7 Pages 2015
Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming Fulltext Access 7 Pages 2015
Microchidia protein 2, MORC2, downregulates the cytoskeleton adapter protein, ArgBP2, via histone methylation in gastric cancer cells Fulltext Access 7 Pages 2015
MicroRNA-128b suppresses tumor growth and promotes apoptosis by targeting A2bR in gastric cancer Fulltext Access 7 Pages 2015
RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes Fulltext Access 7 Pages 2015
Identification of protein arginine N-methyltransferase 5 (PRMT5) as a novel interacting protein with the tumor suppressor protein RASSF1A Fulltext Access 7 Pages 2015
Tri-iodothyronine preconditioning protects against liver ischemia reperfusion injury through the regulation of autophagy by the MEK/ERK/mTORC1 axis Fulltext Access 7 Pages 2015
Dunnione ameliorates cisplatin-induced small intestinal damage by modulating NAD+ metabolism Fulltext Access 7 Pages 2015
MiR-564 functions as a tumor suppressor in human lung cancer by targeting ZIC3 Fulltext Access 7 Pages 2015
β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway Fulltext Access 7 Pages 2015
UDP-glucose pyrophosphorylase Ugp1 is involved in oxidative stress response and long-term survival during stationary phase in Saccharomyces cerevisiae Fulltext Access 7 Pages 2015
Fisetin induces Sirt1 expression while inhibiting early adipogenesis in 3T3-L1 cells Fulltext Access 7 Pages 2015
Characterization of WRKY transcription factors in Solanum lycopersicum reveals collinearity and their expression patterns under cold treatment Fulltext Access 7 Pages 2015
Acidic environment augments FcεRI-mediated production of IL-6 and IL-13 in mast cells Fulltext Access 7 Pages 2015
Expression and potential role of the peptide orexin-A in prostate cancer Fulltext Access 7 Pages 2015
Interactions of cullin3/KCTD5 complexes with both cytoplasmic and nuclear proteins: Evidence for a role in protein stabilization Fulltext Access 7 Pages 2015
Sonic hedgehog stimulates glycolysis and proliferation of breast cancer cells: Modulation of PFKFB3 activation Fulltext Access 7 Pages 2015
rhTNFR:Fc increases Nrf2 expression via miR-27a mediation to protect myocardium against sepsis injury Fulltext Access 7 Pages 2015
FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1-induced transcription Fulltext Access 7 Pages 2015
Anti-infective peptide IDR-1002 augments monocyte chemotaxis towards CCR5 chemokines Fulltext Access 7 Pages 2015
Mitochondrial ATP synthasome: Expression and structural interaction of its components Fulltext Access 7 Pages 2015
LMAN1 (ERGIC-53) is a potential carrier protein for matrix metalloproteinase-9 glycoprotein secretion Fulltext Access 7 Pages 2015
Collagen esterification enhances the function and survival of pancreatic β cells in 2D and 3D culture systems Fulltext Access 7 Pages 2015
MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha Fulltext Access 7 Pages 2015
A somatic T15091C mutation in the Cytb gene of mouse mitochondrial DNA dominantly induces respiration defects Fulltext Access 7 Pages 2015
Hypermethylation of MST1 in IgG4-related autoimmune pancreatitis and rheumatoid arthritis Fulltext Access 7 Pages 2015
C-mannosylation of thrombopoietin receptor (c-Mpl) regulates thrombopoietin-dependent JAK-STAT signaling Fulltext Access 7 Pages 2015
Blockade of Drp1 rescues oxidative stress-induced osteoblast dysfunction Fulltext Access 7 Pages 2015
Genome-wide identification and expression profiling analysis of trihelix gene family in tomato Fulltext Access 7 Pages 2015
Islet-specific monoamine oxidase A and B expression depends on MafA transcriptional activity and is compromised in type 2 diabetes Fulltext Access 7 Pages 2015
A salmon DNA scaffold promotes osteogenesis through activation of sodium-dependent phosphate cotransporters Fulltext Access 7 Pages 2015
Involvement of periostin-sclerostin-Wnt/β-catenin signaling pathway in the prevention of neurectomy-induced bone loss by naringin Fulltext Access 7 Pages 2015
Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) - dependent intracellular trafficking through recycling endosomes Fulltext Access 7 Pages 2015
Escin activates AKT-Nrf2 signaling to protect retinal pigment epithelium cells from oxidative stress Fulltext Access 7 Pages 2015
Nuclear orphan receptor TLX affects gene expression, proliferation and cell apoptosis in beta cells Fulltext Access 7 Pages 2015
Activation of the NLRP3 inflammasome induces vascular dysfunction in obese OLETF rats Fulltext Access 7 Pages 2015
CCAAT/enhancer-binding protein CEBP-2 controls fat consumption and fatty acid desaturation in Caenorhabditis elegans Fulltext Access 7 Pages 2015
GIV/girdin binds exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles Fulltext Access 7 Pages 2015
Long non-coding MIAT mediates high glucose-induced renal tubular epithelial injury Fulltext Access 7 Pages 2015
Dual mTORC1/2 inhibition by INK-128 results in antitumor activity in preclinical models of osteosarcoma Fulltext Access 7 Pages 2015
Critical role of ARID3B in the expression of pro-apoptotic p53-target genes and apoptosis Fulltext Access 7 Pages 2015
Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas Fulltext Access 7 Pages 2015
Del-1 overexpression potentiates lung cancer cell proliferation and invasion Fulltext Access 7 Pages 2015
NOX1 mediates chemoresistance via HIF1α/MDR1 pathway in gallbladder cancer Fulltext Access 7 Pages 2015
The calcium sensor CBL7 modulates plant responses to low nitrate in Arabidopsis Fulltext Access 7 Pages 2015
Administration of sulfosuccinimidyl-4-[N-maleimidomethyl] cyclohexane-1-carboxylate conjugated GP10025-33 peptide-coupled spleen cells effectively mounts antigen-specific immune response against mouse melanoma Fulltext Access 7 Pages 2015
The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation Fulltext Access 7 Pages 2015
Yeast Cyc8p and Tup1p proteins function as coactivators for transcription of Stp1/2p-dependent amino acid transporter genes Fulltext Access 7 Pages 2015
Repression of HNF1α-mediated transcription by amino-terminal enhancer of split (AES) Fulltext Access 7 Pages 2015
Elevated host lipid metabolism revealed by iTRAQ-based quantitative proteomic analysis of cerebrospinal fluid of tuberculous meningitis patients Fulltext Access 7 Pages 2015
Overexpression of Arl6ip5 in osteoblast regulates RANKL subcellualr localization Fulltext Access 7 Pages 2015
Astragaloside IV suppresses transforming growth factor-β1 induced fibrosis of cultured mouse renal fibroblasts via inhibition of the MAPK and NF-κB signaling pathways Fulltext Access 7 Pages 2015
Kruppel-like factor 2 inhibit the angiogenesis of cultured human liver sinusoidal endothelial cells through the ERK1/2 signaling pathway Fulltext Access 7 Pages 2015
Proinflammatory cytokines downregulate connexin 43-gap junctions via the ubiquitin-proteasome system in rat spinal astrocytes Fulltext Access 7 Pages 2015
Characterization of two MODY2 mutations with different susceptibility to activation Fulltext Access 7 Pages 2015
Upregulation of B23 promotes tumor cell proliferation and predicts poor prognosis in glioma Fulltext Access 7 Pages 2015
Fluid shear stress inhibits TNF-α-induced osteoblast apoptosis via ERK5 signaling pathway Fulltext Access 7 Pages 2015
Osteogenic growth peptide promotes osteogenic differentiation of mesenchymal stem cells mediated by LncRNA AK141205-induced upregulation of CXCL13 Fulltext Access 7 Pages 2015
GLP-1 contributes to increases in PGC-1α expression by downregulating miR-23a to reduce apoptosis Fulltext Access 7 Pages 2015
Phosphorylation at the N-terminal finger subdomain of a viral RNA-dependent RNA polymerase Fulltext Access 7 Pages 2015
Extracellular polysaccharide from Bordetella species reduces high glucose-induced macrophage apoptosis via regulating interaction between caveolin-1 and TLR4 Fulltext Access 7 Pages 2015
A high-sensitive HMab-2 specifically detects IDH1-R132H, the most common IDH mutation in gliomas Fulltext Access 7 Pages 2015
Intracellular pH imaging in cancer cells in vitro and tumors in vivo using the new genetically encoded sensor SypHer2 Fulltext Access 7 Pages 2015
Apelin-13 impedes foam cell formation by activating Class III PI3K/Beclin-1-mediated autophagic pathway Fulltext Access 7 Pages 2015
Site specific oxidation of amino acid residues in rat lens γ-crystallin induced by low-dose γ-irradiation Fulltext Access 7 Pages 2015
Tenuigenin inhibits RANKL-induced osteoclastogenesis by down-regulating NF-κB activation and suppresses bone loss in vivo Fulltext Access 7 Pages 2015
TRAF1 knockdown alleviates palmitate-induced insulin resistance in HepG2 cells through NF-κB pathway Fulltext Access 7 Pages 2015
Identification of putative odorant binding protein genes in Asecodes hispinarum, a parasitoid of coconut leaf beetle (Brontispa longissima) by antennal RNA-Seq analysis Fulltext Access 7 Pages 2015
Characterization and sub-cellular localization of GalNAc-binding proteins isolated from human hepatic stellate cells Fulltext Access 7 Pages 2015
MiR-661 inhibits glioma cell proliferation, migration and invasion by targeting hTERT Fulltext Access 7 Pages 2015
miR-4792 inhibits epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma by targeting FOXC1 Fulltext Access 7 Pages 2015
Overexpression of the autophagy-related gene SiATG8a from foxtail millet (Setaria italica L.) confers tolerance to both nitrogen starvation and drought stress in Arabidopsis Fulltext Access 7 Pages 2015
Protective effect of carbenoxolone on ER stress-induced cell death in hypothalamic neurons Fulltext Access 7 Pages 2015
miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2 Fulltext Access 7 Pages 2015