Effects of high glucose and advanced glycation end products on the expressions of sclerostin and RANKL as well as apoptosis in osteocyte-like MLO-Y4-A2 cells Fulltext Access 7 Pages 2015
A tryptophan derivative TD-26 attenuates thrombus formation by inhibiting both PI3K/Akt signaling and binding of fibrinogen to integrin αIIbβ3 Fulltext Access 7 Pages 2015
Autophagy inhibition sensitizes KU-0063794-mediated anti-HepG2 hepatocellular carcinoma cell activity in vitro and in vivo Fulltext Access 7 Pages 2015
Isoform-specific dynamic translocation of PKC by α1-adrenoceptor stimulation in live cells Fulltext Access 7 Pages 2015
Human FAD synthase is a bi-functional enzyme with a FAD hydrolase activity in the molybdopterin binding domain Fulltext Access 7 Pages 2015
MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study Fulltext Access 7 Pages 2015
MiR-30a-5p is induced by Wnt/β-catenin pathway and promotes glioma cell invasion by repressing NCAM Fulltext Access 7 Pages 2015
Targeted activation of endothelin-1 exacerbates hypoxia-induced pulmonary hypertension Fulltext Access 7 Pages 2015
Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7 Fulltext Access 7 Pages 2015
Two specific membrane-bound aminopeptidase N isoforms from Aedes aegypti larvae serve as functional receptors for the Bacillus thuringiensis Cry4Ba toxin implicating counterpart specificity Fulltext Access 7 Pages 2015
Nutlin-3 down-regulates retinoblastoma protein expression and inhibits muscle cell differentiation Fulltext Access 7 Pages 2015
Intensified autophagy compromises the efficacy of radiotherapy against prostate cancer Fulltext Access 7 Pages 2015
In vivo characterization of human myofibrillar myopathy genes in zebrafish Fulltext Access 7 Pages 2015
Improving the activity of the subtilisin nattokinase by site-directed mutagenesis and molecular dynamics simulation Fulltext Access 7 Pages 2015
Cell proliferation is a key determinant of the outcome of FOXO3a activation Fulltext Access 7 Pages 2015
The poplar basic helix-loop-helix transcription factor BEE3 - Like gene affects biomass production by enhancing proliferation of xylem cells in poplar Fulltext Access 7 Pages 2015
Pre-stimulation with FGF-2 increases in vitro functional coupling of mesenchymal stem cells with cardiac cells Fulltext Access 7 Pages 2015
MAR binding protein SMAR1 favors IL-10 mediated regulatory T cell function in acute colitis Fulltext Access 7 Pages 2015
XCR1 promotes cell growth and migration and is correlated with bone metastasis in non-small cell lung cancer Fulltext Access 7 Pages 2015
Insulin-like growth factor-1 suppresses the Myostatin signaling pathway during myogenic differentiation Fulltext Access 7 Pages 2015
The actin family protein ARP6 contributes to the structure and the function of the nucleolus Fulltext Access 7 Pages 2015
Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer Fulltext Access 7 Pages 2015
Application of GC-MS coupled with chemometrics for scanning serum metabolic biomarkers from renal fibrosis rat Fulltext Access 7 Pages 2015
miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma Fulltext Access 7 Pages 2015
Ubiquitin E3 ligase UHRF1 regulates p53 ubiquitination and p53-dependent cell apoptosis in clear cell Renal Cell Carcinoma Fulltext Access 7 Pages 2015
Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe Fulltext Access 7 Pages 2015
Interaction between mitsugumin 29 and TRPC3 participates in regulating Ca2+ transients in skeletal muscle Fulltext Access 7 Pages 2015
SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia Fulltext Access 7 Pages 2015
Sgk1 regulates desmoglein 1 expression levels in oligodendrocytes in the mouse corpus callosum after chronic stress exposure Fulltext Access 7 Pages 2015
Single high-dose irradiation aggravates eosinophil-mediated fibrosis through IL-33 secreted from impaired vessels in the skin compared to fractionated irradiation Fulltext Access 7 Pages 2015
Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes Fulltext Access 7 Pages 2015
CCN3 overexpression inhibits growth of callosal projections via upregulation of RAB25 Fulltext Access 7 Pages 2015
LRIG1, a 3p tumor suppressor, represses EGFR signaling and is a novel epigenetic silenced gene in colorectal cancer Fulltext Access 7 Pages 2015
Metformin inhibits the proliferation of human prostate cancer PC-3 cells via the downregulation of insulin-like growth factor 1 receptor Fulltext Access 7 Pages 2015
Identification and characterization of three novel hemocyte-specific promoters in silkworm Bombyx mori Fulltext Access 7 Pages 2015
Cloning and characterization of HbMT2a, a metallothionein gene from Hevea brasiliensis Muell. Arg differently responds to abiotic stress and heavy metals Fulltext Access 7 Pages 2015
Annexin-A1 controls an ERK-RhoA-NFκB activation loop in breast cancer cells Fulltext Access 7 Pages 2015
EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells Fulltext Access 7 Pages 2015
β-Catenin expression is regulated by an IRES-dependent mechanism and stimulated by paclitaxel in human ovarian cancer cells Fulltext Access 7 Pages 2015
Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states Fulltext Access 7 Pages 2015
Adenylyl cyclase localization to the uropod of aggregating Dictyostelium cells requires RacC Fulltext Access 7 Pages 2015
Fentanyl inhibits the invasion and migration of colorectal cancer cells via inhibiting the negative regulation of Ets-1 on BANCR Fulltext Access 7 Pages 2015
ANGUSTIFOLIA mediates one of the multiple SCRAMBLED signaling pathways regulating cell growth pattern in Arabidopsis thaliana Fulltext Access 7 Pages 2015
Stanniocalcin 2 promotes cell proliferation and cisplatin resistance in cervical cancer Fulltext Access 7 Pages 2015
Expression patterns of long noncoding RNAs from Dlk1-Dio3 imprinted region and the potential mechanisms of Gtl2 activation during blastocyst development Fulltext Access 7 Pages 2015
HCV core protein promotes hepatocyte proliferation and chemoresistance by inhibiting NR4A1 Fulltext Access 7 Pages 2015
Fibulin-5 deficiency causes developmental defect of premaxillary bone in mice Fulltext Access 7 Pages 2015
Loss of PTEN causes SHP2 activation, making lung cancer cells unresponsive to IFN-γ Fulltext Access 7 Pages 2015
DNA-PKcs interference sensitizes colorectal cancer cells to a mTOR kinase inhibitor WAY-600 Fulltext Access 7 Pages 2015
Foxp3-dependent transformation of human primary CD4+ T lymphocytes by the retroviral protein tax Fulltext Access 7 Pages 2015
Evans Blue is not a suitable inhibitor of the epithelial sodium channel δ-subunit Fulltext Access 7 Pages 2015
Orai1 forms a signal complex with SK3 channel in gallbladder smooth muscle Fulltext Access 7 Pages 2015
Crystal structure and characterization of a novel l-serine ammonia-lyase from Rhizomucor miehei Fulltext Access 7 Pages 2015
Functional requirement of tyrosine residue 429 within CD5 cytoplasmic domain for regulation of T cell activation and survival Fulltext Access 7 Pages 2015
Endoplasmic reticulum stress activation mediates Ginseng Rg3-induced anti-gallbladder cancer cell activity Fulltext Access 7 Pages 2015
Enhancement of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems. Relevance for neuroplasticity and depression Fulltext Access 7 Pages 2015
Hyaluronan-induced VEGF-C promotes fibrosis-induced lymphangiogenesis via Toll-like receptor 4-dependent signal pathway Fulltext Access 7 Pages 2015
Transduction of Oct6 or Oct9 gene concomitant with Myc family gene induced osteoblast-like phenotypic conversion in normal human fibroblasts Fulltext Access 7 Pages 2015
Identification of the neural crest-specific enhancer of Seraf gene in avian peripheral nervous system development Fulltext Access 7 Pages 2015
Different effects of resveratrol on early and late passage mesenchymal stem cells through β-catenin regulation Fulltext Access 7 Pages 2015
Self-assembly formed by a short DNA probe pair: Application for highly sensitive mRNA species detection without reverse transcription Fulltext Access 7 Pages 2015
Short-term selective alleviation of glucotoxicity and lipotoxicity ameliorates the suppressed expression of key β-cell factors under diabetic conditions Fulltext Access 7 Pages 2015
Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo Fulltext Access 7 Pages 2015
MiR-506 suppresses cell proliferation and tumor growth by targeting Rho-associated protein kinase 1 in hepatocellular carcinoma Fulltext Access 7 Pages 2015
Olanzapine promotes the accumulation of lipid droplets and the expression of multiple perilipins in human adipocytes Fulltext Access 7 Pages 2015
Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis Fulltext Access 7 Pages 2015
HSP27 phosphorylation protects against endothelial barrier dysfunction under burn serum challenge Fulltext Access 7 Pages 2015
Girdin/GIV is upregulated by cyclic tension, propagates mechanical signal transduction, and is required for the cellular proliferation and migration of MG-63 cells Fulltext Access 7 Pages 2015
mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior Fulltext Access 7 Pages 2015
Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death Fulltext Access 7 Pages 2015
Amino-terminal residues of ÎNp63, mutated in ectodermal dysplasia, are required for its transcriptional activity Fulltext Access 7 Pages 2015
Pexophagy is induced by increasing peroxisomal reactive oxygen species in 1â²10-phenanthroline-treated cells Fulltext Access 7 Pages 2015
O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities Fulltext Access 7 Pages 2015
Implication of a galactomannan-binding GH2 β-mannosidase in mannan utilization by Caldicellulosiruptor bescii Fulltext Access 7 Pages 2015
Curcumin inhibits development and cell adhesion in Dictyostelium discoideum: Implications for YakA signaling and GST enzyme function Fulltext Access 7 Pages 2015
Crystal structure analysis of a bacterial aryl acylamidase belonging to the amidase signature enzyme family Fulltext Access 7 Pages 2015
MicroRNA-139-5p acts as a tumor suppressor by targeting ELTD1 and regulating cell cycle in glioblastoma multiforme Fulltext Access 7 Pages 2015
PERK pathway is involved in oxygen-glucose-serum deprivation-induced NF-kB activation via ROS generation in spinal cord astrocytes Fulltext Access 7 Pages 2015
Five pectinase gene expressions highly responding to heat stress in rice floral organs revealed by RNA-seq analysis Fulltext Access 7 Pages 2015
Erbin loss promotes cancer cell proliferation through feedback activation of Akt-Skp2-p27 signaling Fulltext Access 7 Pages 2015
Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasion and migration in nasopharyngeal cancer cells Fulltext Access 7 Pages 2015
ER stress-associated CTRC mutants decrease stimulated pancreatic zymogen secretion through SIRT2-mediated microtubule dysregulation Fulltext Access 7 Pages 2015
miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2 Fulltext Access 7 Pages 2015
MicroRNA-204 suppresses trophoblast-like cell invasion by targeting matrix metalloproteinase-9 Fulltext Access 7 Pages 2015
DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line Fulltext Access 7 Pages 2015
Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection Fulltext Access 7 Pages 2015
Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor Fulltext Access 7 Pages 2015
Changes in white and brown adipose tissue microRNA expression in cold-induced mice Fulltext Access 7 Pages 2015