Cholesterol reduces the sensitivity to platinum-based chemotherapy via upregulating ABCG2 in lung adenocarcinoma Fulltext Access 7 Pages 2015
Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells Fulltext Access 7 Pages 2015
Targeting of the deubiquitinase USP9X attenuates B-cell acute lymphoblastic leukemia cell survival and overcomes glucocorticoid resistance Fulltext Access 7 Pages 2015
Cancer cell-associated cytoplasmic B7-H4 is induced by hypoxia through hypoxia-inducible factor-1α and promotes cancer cell proliferation Fulltext Access 7 Pages 2015
VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability Fulltext Access 7 Pages 2015
CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells Fulltext Access 7 Pages 2015
b-series gangliosides crucially regulate leptin secretion in adipose tissues Fulltext Access 7 Pages 2015
Tivantinib (ARQ-197) exhibits anti-tumor activity with down-regulation of FAK in oral squamous cell carcinoma Fulltext Access 7 Pages 2015
Type I collagen gel protects murine fibrosarcoma L929 cells from TNFα-induced cell death Fulltext Access 7 Pages 2015
Inhibition of STAT3/cyclinD1 pathway promotes chemotherapeutic sensitivity of colorectal caner Fulltext Access 7 Pages 2015
Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species Fulltext Access 7 Pages 2015
In vitro selection and characterization of deoxyribonucleic acid aptamers against connective tissue growth factor Fulltext Access 7 Pages 2015
Biophysical characterization of interactions between the C-termini of peripheral nerve claudins and the PDZ1 domain of zonula occludens Fulltext Access 7 Pages 2015
Endothelial-monocyte-activating polypeptide II induces rat C6 glioma cell apoptosis via the mitochondrial pathway Fulltext Access 7 Pages 2015
TRAM1 protect HepG2 cells from palmitate induced insulin resistance through ER stress-JNK pathway Fulltext Access 7 Pages 2015
Biochemical and molecular characterization of novel mutations in GLB1 and NEU1 in patient cells with lysosomal storage disorders Fulltext Access 7 Pages 2015
Construction of nerve guide conduits from cellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect Fulltext Access 7 Pages 2015
17β-Estradiol regulates cell proliferation, colony formation, migration, invasion and promotes apoptosis by upregulating miR-9 and thus degrades MALAT-1 in osteosarcoma cell MG-63 in an estrogen receptor-independent manner Fulltext Access 7 Pages 2015
Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish Fulltext Access 7 Pages 2015
LRD-22, a novel dual dithiocarbamatic acid ester, inhibits Aurora-A kinase and induces apoptosis and cell cycle arrest in HepG2 cells Fulltext Access 7 Pages 2015
Identification of a novel stress regulated FERM domain containing cytosolic protein having PTP activity in Setaria cervi, a bovine filarial parasite Fulltext Access 7 Pages 2015
Integrin α6β4 and TRPV1 channel coordinately regulate directional keratinocyte migration Fulltext Access 7 Pages 2015
YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead-dependent manner Fulltext Access 7 Pages 2015
DNA damage and ER stress contribute to oblongifolin C-induced cell killing in Bax/Bak-deficient cells Fulltext Access 7 Pages 2015
Muscle-selective knockout of AMPKα2 does not exacerbate diet-induced obesity probably related to altered myokines expression Fulltext Access 7 Pages 2015
Eicosapentaenoic acid (EPA) induced apoptosis in HepG2 cells through ROS-Ca2+-JNK mitochondrial pathways Fulltext Access 7 Pages 2015
Deficiency of the 15-kDa selenoprotein led to cytoskeleton remodeling and non-apoptotic membrane blebbing through a RhoA/ROCK pathway Fulltext Access 7 Pages 2015
The histone demethylase KDM4B interacts with MyoD to regulate myogenic differentiation in C2C12 myoblast cells Fulltext Access 7 Pages 2015
Sinapic acid protects heart against ischemia/reperfusion injury and H9c2 cardiomyoblast cells against oxidative stress Fulltext Access 7 Pages 2015
AtTGA4, a bZIP transcription factor, confers drought resistance by enhancing nitrate transport and assimilation in Arabidopsis thaliana Fulltext Access 7 Pages 2015
AMP-activated protein kinase-dependent autophagy mediated the protective effect of sonic hedgehog pathway on oxygen glucose deprivation-induced injury of cardiomyocytes Fulltext Access 7 Pages 2015
EGFR mediates astragaloside IV-induced Nrf2 activation to protect cortical neurons against in vitro ischemia/reperfusion damages Fulltext Access 7 Pages 2015
3D-fibroblast tissues constructed by a cell-coat technology enhance tight-junction formation of human colon epithelial cells Fulltext Access 7 Pages 2015
Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease Fulltext Access 7 Pages 2015
Functional properties of Claramine: A novel PTP1B inhibitor and insulin-mimetic compound Fulltext Access 7 Pages 2015
Inhibition of HIV-1 entry by the tricyclic coumarin GUT-70 through the modification of membrane fluidity Fulltext Access 7 Pages 2015
Imp2, the PSTPIP homolog in fission yeast, affects sensitivity to the immunosuppressant FK506 and membrane trafficking in fission yeast Fulltext Access 7 Pages 2015
Redox sensor proteins for highly sensitive direct imaging of intracellular redox state Fulltext Access 7 Pages 2015
miR-25 modulates NSCLC cell radio-sensitivity through directly inhibiting BTG2 expression Fulltext Access 7 Pages 2015
Proteoglycan from salmon nasal cartridge promotes in vitro wound healing of fibroblast monolayers via the CD44 receptor Fulltext Access 7 Pages 2015
Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10 Fulltext Access 7 Pages 2015
The N-terminal leucine-zipper motif in PTRF/cavin-1 is essential and sufficient for its caveolae-association Fulltext Access 7 Pages 2015
Tbx3 and Nr5α2 improve the viability of porcine induced pluripotent stem cells after dissociation into single cells by inhibiting RHO-ROCK-MLC signaling Fulltext Access 7 Pages 2015
A cell-free system toward deciphering the post-translational modification barcodes of Oct4 in different cellular contexts Fulltext Access 7 Pages 2015
De novo design based pharmacophore query generation and virtual screening for the discovery of Hsp-47 inhibitors Fulltext Access 7 Pages 2015
Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans Fulltext Access 7 Pages 2015
G protein coupled receptor 50 promotes self-renewal and neuronal differentiation of embryonic neural progenitor cells through regulation of notch and wnt/β-catenin signalings Fulltext Access 7 Pages 2015
A novel major facilitator transporter TrSTR1 is essential for pentose utilization and involved in xylanase induction in Trichoderma reesei Fulltext Access 7 Pages 2015
REV1 is important for the ATR-Chk1 DNA damage response pathway in Xenopus egg extracts Fulltext Access 7 Pages 2015
Fluid shear stress promotes proprotein convertase-dependent activation of MT1-MMP Fulltext Access 7 Pages 2015
Microvesicles released constitutively from prostate cancer cells differ biochemically and functionally to stimulated microvesicles released through sublytic C5b-9 Fulltext Access 7 Pages 2015
IRE1α-TRAF2-ASK1 complex-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to CXC195-induced apoptosis in human bladder carcinoma T24 cells Fulltext Access 7 Pages 2015
Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion Fulltext Access 7 Pages 2015
Prostate cancer cells stimulated by calcium-mediated activation of protein kinase C undergo a refractory period before re-releasing calcium-bearing microvesicles Fulltext Access 7 Pages 2015
Endothelin-1 exacerbates development of hypertension and atherosclerosis in modest insulin resistant syndrome Fulltext Access 7 Pages 2015
Rhamnazin, a novel inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy Fulltext Access 7 Pages 2015
SUMO-fusion, purification, and characterization of a (+)-zizaene synthase from Chrysopogon zizanioides Fulltext Access 7 Pages 2015
Protective effects of aerobic swimming training on high-fat diet induced nonalcoholic fatty liver disease: Regulation of lipid metabolism via PANDER-AKT pathway Fulltext Access 7 Pages 2015
HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma Fulltext Access 7 Pages 2015
Adenosine induces apoptosis through TNFR1/RIPK1/P38 axis in colon cancer cells Fulltext Access 7 Pages 2015
Myocardial regeneration in adriamycin cardiomyopathy by nuclear expression of GLP1 using ultrasound targeted microbubble destruction Fulltext Access 7 Pages 2015
Expression of autophagy-related proteins ATG5 and FIP200 predicts favorable disease-free survival in patients with breast cancer Fulltext Access 7 Pages 2015
The anti-hypertensive drug reserpine induces neuronal cell death through inhibition of autophagic flux Fulltext Access 7 Pages 2015
Down-regulation of 14-3-3β exerts anti-cancer effects through inducing ER stress in human glioma U87 cells: Involvement of CHOP-Wnt pathway Fulltext Access 7 Pages 2015
IL-15 induces strong but short-lived tumor-infiltrating CD8 T cell responses through the regulation of Tim-3 in breast cancer Fulltext Access 7 Pages 2015
A novel splice variant of human L-selectin encodes a soluble molecule that is elevated in serum of patients with rheumatic diseases Fulltext Access 7 Pages 2015
The A- and B-type muscarinic acetylcholine receptors from Drosophila melanogaster couple to different second messenger pathways Fulltext Access 7 Pages 2015
The STAT3 inhibitor WP1066 synergizes with vorinostat to induce apoptosis of mantle cell lymphoma cells Fulltext Access 7 Pages 2015
A new kinetochore component CENP-W interacts with the polycomb-group protein EZH2 to promote gene silencing Fulltext Access 7 Pages 2015
Thymosin α1 promotes the activation of myeloid-derived suppressor cells in a Lewis lung cancer model by upregulating Arginase 1 Fulltext Access 7 Pages 2015
MTERF4 regulates the mitochondrial dysfunction induced by MPP+ in SH-SY5Y cells Fulltext Access 7 Pages 2015
Novel odorant-binding proteins and their expression patterns in grasshopper, Oedaleus asiaticus Fulltext Access 7 Pages 2015
Osteopontin-induced brown adipogenesis from white preadipocytes through a PI3K-AKT dependent signaling Fulltext Access 7 Pages 2015
Molecular mechanisms of resistance to human pathogenic bacteria in Caenorhabditis elegans by MEV-1 mediated oxidative stress Fulltext Access 7 Pages 2015
Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells Fulltext Access 7 Pages 2015
EML4-ALK induces epithelial-mesenchymal transition consistent with cancer stem cell properties in H1299 non-small cell lung cancer cells Fulltext Access 7 Pages 2015
MicroRNA-301a modulates doxorubicin resistance in osteosarcoma cells by targeting AMP-activated protein kinase alpha 1 Fulltext Access 7 Pages 2015
MicroRNA-194 promotes osteoblast differentiation via downregulating STAT1 Fulltext Access 7 Pages 2015
MicroRNA-27b plays a role in pulmonary arterial hypertension by modulating peroxisome proliferator-activated receptor γ dependent Hsp90-eNOS signaling and nitric oxide production Fulltext Access 7 Pages 2015
SENP1 inhibition induces apoptosis and growth arrest of multiple myeloma cells through modulation of NF-κB signaling Fulltext Access 7 Pages 2015
Roles of PTEN-induced putative kinase 1 and dynamin-related protein 1 in transient global ischemia-induced hippocampal neuronal injury Fulltext Access 7 Pages 2015
IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression Fulltext Access 7 Pages 2015
Ablation of C/EBP homologous protein increases the acute phase mortality and doesn't attenuate cardiac remodeling in mice with myocardial infarction Fulltext Access 7 Pages 2015
Activating PTEN by COX-2 inhibitors antagonizes radiation-induced AKT activation contributing to radiosensitization Fulltext Access 7 Pages 2015
Extracellular acidification synergizes with PDGF to stimulate migration of mouse embryo fibroblasts through activation of p38MAPK with a PTX-sensitive manner Fulltext Access 7 Pages 2015
Single chain antibody fragment with serine protease inhibitory property capable of neutralizing toxicity of Trimeresurus mucrosquamatus venom Fulltext Access 7 Pages 2015
Dexamethasone-induced apoptosis of osteocytic and osteoblastic cells is mediated by TAK1 activation Fulltext Access 7 Pages 2015
A chemically defined culture medium containing Rho kinase inhibitor Y-27632 for the fabrication of stratified squamous epithelial cell grafts Fulltext Access 7 Pages 2015
P2Y purinergic receptor-regulated insulin secretion is mediated by a cAMP/Epac/Kv channel pathway Fulltext Access 7 Pages 2015
Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerves Fulltext Access 7 Pages 2015
miR-107 and miR-25 simultaneously target LATS2 and regulate proliferation and invasion of gastric adenocarcinoma (GAC) cells Fulltext Access 7 Pages 2015
Resolvin D2 recovers neural injury by suppressing inflammatory mediators expression in lipopolysaccharide-induced Parkinson's disease rat model Fulltext Access 7 Pages 2015