A xenograft model reveals that PU.1 functions as a tumor suppressor for multiple myeloma in vivo Fulltext Access 7 Pages 2017
ALG2 regulates glioblastoma cell proliferation, migration and tumorigenicity Fulltext Access 7 Pages 2017
Amelioration of serum 8-OHdG level by enzyme replacement therapy in patients with Fabry cardiomyopathy Fulltext Access 7 Pages 2017
Differential expression of ST6GAL1 in the tumor progression of colorectal cancer Fulltext Access 7 Pages 2017
Piperlongumine downregulates the expression of HER family in breast cancer cells Fulltext Access 7 Pages 2017
EGFR tyrosine kinase inhibitors differentially affect autophagy in head and neck squamous cell carcinoma Fulltext Access 7 Pages 2017
Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1 Fulltext Access 7 Pages 2017
Neoagarooligosaccharides prevent septic shock by modulating A20-and cyclooxygenase-2-mediated interleukin-10 secretion in a septic-shock mouse model Fulltext Access 7 Pages 2017
Impact of antibody subclass and disulfide isoform differences on the biological activity of CD200R and βklotho agonist antibodies Fulltext Access 7 Pages 2017
Inhibition of N-glycan processing modulates the network of EDEM3 interactors Fulltext Access 7 Pages 2017
A vesicle trafficking protein αSNAP regulates Paneth cell differentiation in vivo Fulltext Access 7 Pages 2017
Functional characterization of the Arabidopsis universal stress protein AtUSP with an antifungal activity Fulltext Access 7 Pages 2017
Protective effects of Zn2+ against cobalt nanoparticles and cobalt chloride-induced cytotoxicity of RAW 264.7cells via ROS pathway Fulltext Access 7 Pages 2017
Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression Fulltext Access 7 Pages 2017
Quantitative visualization of synchronized insulin secretion from 3D-cultured cells Fulltext Access 7 Pages 2017
A CO-releasing molecule prevents annexin A2 down-regulation and associated disorders in LPS-administered rat lung Fulltext Access 7 Pages 2017
TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells Fulltext Access 7 Pages 2017
miR-221 regulates CD44 in hepatocellular carcinoma through the PI3K-AKT-mTOR pathway Fulltext Access 7 Pages 2017
Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae Fulltext Access 7 Pages 2017
Age-related increase in Wnt inhibitor causes a senescence-like phenotype in human cardiac stem cells Fulltext Access 7 Pages 2017
Influence of ER leak on resting cytoplasmic Ca2+ and receptor-mediated Ca2+ signalling in human macrophage Fulltext Access 7 Pages 2017
Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic β-cells Fulltext Access 7 Pages 2017
Loss of MURC/Cavin-4 induces JNK and MMP-9 activity enhancement in vascular smooth muscle cells and exacerbates abdominal aortic aneurysm Fulltext Access 7 Pages 2017
Crystal structure of the flagellar chaperone FliS from Bacillus cereus and an invariant proline critical for FliS dimerization and flagellin recognition Fulltext Access 7 Pages 2017
Loss of FKBP5 impedes adipocyte differentiation under both normoxia and hypoxic stress Fulltext Access 7 Pages 2017
Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage Fulltext Access 7 Pages 2017
Over-expression of CHAF1A in Epithelial Ovarian Cancer can promote cell proliferation and inhibit cell apoptosis Fulltext Access 7 Pages 2017
Regulation of REST levels overcomes dysregulation of neural stem cell differentiation caused by disruption of polyubiquitin gene Ubb Fulltext Access 7 Pages 2017
Loss of Gspt1l disturbs the patterning of the brain central arteries in zebrafish Fulltext Access 7 Pages 2017
Biochemical characterization of rhamnosyltransferase involved in biosynthesis of pectic rhamnogalacturonan I in plant cell wall Fulltext Access 7 Pages 2017
Bimodal expression of yeast GAL genes is controlled by a long non-coding RNA and a bifunctional galactokinase Fulltext Access 7 Pages 2017
Effects of naturally occurring charged mutations on the structure, stability, and binding of the Pin1 WW domain Fulltext Access 7 Pages 2017
The LncRNA ZBED3-AS1 induces chondrogenesis of human synovial fluid mesenchymal stem cells Fulltext Access 7 Pages 2017
Characterization of the rax1 gene encoding a putative regulator of G protein signaling in Aspergillus fumigatus Fulltext Access 7 Pages 2017
Peptidoglycan accelerates granulopoiesis through a TLR2- and MyD88-dependent pathway Fulltext Access 7 Pages 2017
Differential regulation of the lipoxygenase pathway in shrimp hepatopancreases and ovaries during ovarian development in the black tiger shrimp Penaeus monodon Fulltext Access 7 Pages 2017
Characterization of the novel protein KIAA0564 (Von Willebrand Domain-containing Protein 8) Fulltext Access 7 Pages 2017
Impaired degradation of medullary WNK4 in the kidneys of KLHL2 knockout mice Fulltext Access 7 Pages 2017
Impact of G-quadruplex loop conformation in the PITX1 mRNA on protein and small molecule interaction Fulltext Access 7 Pages 2017
Potentiation of docetaxel sensitivity by miR-638 via regulation of STARD10 pathway in human breast cancer cells Fulltext Access 7 Pages 2017
Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases Fulltext Access 7 Pages 2017
EpCAM controls morphogenetic programs during zebrafish pronephros development Fulltext Access 7 Pages 2017
A cell-autonomous positive-signaling circuit associated with the PDGF-NO-ID4-regulatory axis in glioblastoma cells Fulltext Access 7 Pages 2017
Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR Fulltext Access 7 Pages 2017
AURKA promotes cancer metastasis by regulating epithelial-mesenchymal transition and cancer stem cell properties in hepatocellular carcinoma Fulltext Access 7 Pages 2017
Short-chain fatty acids, GPR41 and GPR43 ligands, inhibit TNF-α-induced MCP-1 expression by modulating p38 and JNK signaling pathways in human renal cortical epithelial cells Fulltext Access 7 Pages 2017
BCL6 mediates the effects of Gastrodin on promoting M2-like macrophage polarization and protecting against oxidative stress-induced apoptosis and cell death in macrophages Fulltext Access 7 Pages 2017
Klotho ameliorates cyclosporine A-induced nephropathy via PDLIM2/NF-kB p65 signaling pathway Fulltext Access 7 Pages 2017
Down-regulation of MsrB3 induces cancer cell apoptosis through reactive oxygen species production and intrinsic mitochondrial pathway activation Fulltext Access 7 Pages 2017
miR-17-92 promotes leukemogenesis in chronic myeloid leukemia via targeting A20 and activation of NF-κB signaling Fulltext Access 7 Pages 2017
Effects of matsutake mushroom scent compounds on tyrosinase and murine B16-F10 melanoma cells Fulltext Access 7 Pages 2017
Brusatol inhibits growth and induces apoptosis in pancreatic cancer cells via JNK/p38 MAPK/NF-κb/Stat3/Bcl-2 signaling pathway Fulltext Access 7 Pages 2017
Lamin A overexpression promotes osteoblast differentiation and calcification in the MC3T3-E1 preosteoblastic cell line Fulltext Access 7 Pages 2017
Prolyl-tRNA synthetase inhibition promotes cell death in SK-MEL-2Â cells through GCN2-ATF4 pathway activation Fulltext Access 7 Pages 2017
Assessing activity of Hepatitis A virus 3C protease using a cyclized luciferase-based biosensor Fulltext Access 7 Pages 2017
Identification of miR-601 as a novel regulator in the development of pancreatic cancer Fulltext Access 7 Pages 2017
Deficiency in ubiquitin-like protein Ubl4A impairs migration of fibroblasts and macrophages Fulltext Access 7 Pages 2017
MicroRNA-340 inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting JAK1 Fulltext Access 7 Pages 2017
Pou1f1, the key transcription factor related to somatic growth in tilapia (Orechromis niloticus), is regulated by two independent post-transcriptional regulation mechanisms Fulltext Access 7 Pages 2017
Identification of AcAP5 as a novel factor Xa inhibitor with both direct and allosteric inhibition Fulltext Access 7 Pages 2017
The Notch ligand delta-like 3 promotes tumor growth and inhibits Notch signaling in lung cancer cells in mice Fulltext Access 7 Pages 2017
Apomorphine suppresses TNF-α-induced MMP-9 expression and cell invasion through inhibition of ERK/AP-1 signaling pathway in MCF-7 cells Fulltext Access 7 Pages 2017
Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells Fulltext Access 7 Pages 2017
Structural mechanism underlying regulation of human EFhd2/Swiprosin-1 actin-bundling activity by Ser183 phosphorylation Fulltext Access 7 Pages 2017
Direct transcriptional activation of BT genes by NLP transcription factors is a key component of the nitrate response in Arabidopsis Fulltext Access 7 Pages 2017
Nongenomic effects of 1α,25-dihydroxyvitamin D3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice Fulltext Access 7 Pages 2017
Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2) Fulltext Access 7 Pages 2017
Biophysical characterization of Ca2+-binding of S100A5 and Ca2+-induced interaction with RAGE Fulltext Access 7 Pages 2017
Repression of miR-217 protects against high glucose-induced podocyte injury and insulin resistance by restoring PTEN-mediated autophagy pathway Fulltext Access 7 Pages 2017
Circadian clock and steroidogenic-related gene expression profiles in mouse Leydig cells following dexamethasone stimulation Fulltext Access 7 Pages 2017
Structural and functional analysis of BF2549, a PadR-like transcription factor from Bacteroides fragilis Fulltext Access 7 Pages 2017
Role of extracellular vesicles in the interaction between epithelial and mesenchymal cells during oviductal ciliogenesis Fulltext Access 7 Pages 2017
Increased urine acylcarnitines in diabetic ApoE-/- mice: Hydroxytetradecadienoylcarnitine (C14:2-OH) reflects diabetic nephropathy in a context of hyperlipidemia Fulltext Access 7 Pages 2017
Probing the acidic residue within the integrin binding site of laminin-511 that interacts with the metal ion-dependent adhesion site of α6β1 integrin Fulltext Access 7 Pages 2017
MafB enhances the phagocytic activity of RAW264.7 macrophages by promoting Fcgr3 expression Fulltext Access 7 Pages 2017
Ectopical expression of FABP4 gene can induce bovine muscle-derived stem cells adipogenesis Fulltext Access 7 Pages 2017
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca2+-calcineurin-NFATc1 signaling pathway Fulltext Access 7 Pages 2017
A secretome analysis reveals that PPARα is upregulated by fractionated-dose γ-irradiation in three-dimensional keratinocyte cultures Fulltext Access 7 Pages 2017
A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells Fulltext Access 7 Pages 2017
Hypoxia pretreatment and EPO-modification enhance the protective effects of MSC on neuron-like PC12Â cells in a similar way Fulltext Access 7 Pages 2017
miR-142-5p regulates tumor cell PD-L1 expression and enhances anti-tumor immunity Fulltext Access 7 Pages 2017
Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity Fulltext Access 7 Pages 2017
Identification and characterization of novel lncRNAs in Arabidopsis thaliana Fulltext Access 7 Pages 2017
Transcriptional activation of NANOG by YBX1 promotes lung cancer stem-like properties and metastasis Fulltext Access 7 Pages 2017
SNHG1 lncRNA negatively regulates miR-199a-3p to enhance CDK7 expression and promote cell proliferation in prostate cancer Fulltext Access 7 Pages 2017
LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway Fulltext Access 7 Pages 2017
Function of Nup98 subtypes and their fusion proteins, Nup98-TopIIβ and Nup98-SETBP1 in nuclear-cytoplasmic transport Fulltext Access 7 Pages 2017
Resveratrol attenuates skeletal muscle atrophy induced by chronic kidney disease via MuRF1 signaling pathway Fulltext Access 7 Pages 2017
MicroRNA-29 regulates myocardial microvascular endothelial cells proliferation and migration in association with IGF1 in type 2 diabetes Fulltext Access 7 Pages 2017
Transcriptional repression of HER2 by ANO1 Clâ channel inhibition in human breast cancer cells with resistance to trastuzumab Fulltext Access 7 Pages 2017
Glaucocalyxin A improves survival in bleomycin-induced pulmonary fibrosis in mice Fulltext Access 7 Pages 2017
Angiogenic factor with G patch and FHA domains 1 (Aggf1) promotes hepatic steatosis in mice Fulltext Access 7 Pages 2017
Functional characterization of archaeal homologs of human nuclear RNase P proteins Rpp21 and Rpp29 provides insights into the molecular basis of their cooperativity in catalysis Fulltext Access 7 Pages 2017
Genetic disruption of tubulin acetyltransferase, αTAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/β-catenin signaling Fulltext Access 7 Pages 2017
Resistance-breaking population of Meloidogyne incognita utilizes plant peroxidase to scavenge reactive oxygen species, thereby promoting parasitism on tomato carrying Mi-1 gene Fulltext Access 7 Pages 2017
LncRNA Gm4419 contributes to OGD/R injury of cerebral microglial cells via IκB phosphorylation and NF-κB activation Fulltext Access 7 Pages 2017
High sugar diet disrupts gut homeostasis though JNK and STAT pathways in Drosophila Fulltext Access 7 Pages 2017