Space and habitat use of the African elephant in the Tarangire–Manyara ecosystem, Tanzania: Implications for conservation Fulltext Access 16 Pages 2006
GroEL Walks the Fine Line: The Subtle Balance of Substrate and Co-chaperonin Binding by GroEL. A Combinatorial Investigation by Design, Selection and Screening Fulltext Access 16 Pages 2006
Computational Study of the Fibril Organization of Polyglutamine Repeats Reveals a Common Motif Identified in β-Helices Fulltext Access 16 Pages 2006
A Critical Coiled Coil Motif in the Small Terminase, gp16, from Bacteriophage T4: Insights into DNA Packaging Initiation and Assembly of Packaging Motor Fulltext Access 16 Pages 2006
Molecular Structure of fd (f1, M13) Filamentous Bacteriophage Refined with Respect to X-ray Fibre Diffraction and Solid-state NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane Fulltext Access 16 Pages 2006
Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T. vivax: Enzyme Conformational Changes and Implications for Catalysis Fulltext Access 16 Pages 2006
Effects of oxidative stress on the cardiac myocyte proteome: modifications to peroxiredoxins and small heat shock proteins Fulltext Access 16 Pages 2006
Variations in the diet and population density of the red fox Vulpes vulpes in the mixed woodlands of northern Belarus Fulltext Access 16 Pages 2006
Solution Conformation and Heparin-induced Dimerization of the Full-length Extracellular Domain of the Human Amyloid Precursor Protein Fulltext Access 16 Pages 2006
Characterization of Intra-molecular Distances and Site-specific Dynamics in Chemically Unfolded Barstar: Evidence for Denaturant-dependent Non-random Structure Fulltext Access 16 Pages 2006
The Asymmetric IscA Homodimer with an Exposed [2Fe-2S] Cluster Suggests the Structural Basis of the Fe-S Cluster Biosynthetic Scaffold Fulltext Access 16 Pages 2006
DM2 CCTG•CAGG Repeats are Crossover Hotspots that are More Prone to Expansions than the DM1 CTG•CAG Repeats in Escherichia coli Fulltext Access 16 Pages 2006
Tetramerization of the LexA Repressor in Solution: Implications for Gene Regulation of the E. coli SOS System at Acidic pH Fulltext Access 16 Pages 2006
Drosophila CK2 regulates lateral-inhibition during eye and bristle development Fulltext Access 16 Pages 2006
An essential role for zebrafish Fgfrl1 during gill cartilage development Fulltext Access 16 Pages 2006
Transcriptional upregulation of the C. elegans Hox gene lin-39 during vulval cell fate specification Fulltext Access 16 Pages 2006
Crystal Structure of the Archaeal A1AO ATP Synthase Subunit B from Methanosarcina mazei Gö1: Implications of Nucleotide-binding Differences in the Major A1AO Subunits A and B Fulltext Access 16 Pages 2006
Rigidity and Flexibility of Dipeptidyl Peptidase IV: Crystal Structures of and Docking Experiments with DPIV Fulltext Access 16 Pages 2006
A Single Mutation Induces Amyloid Aggregation in the α-Spectrin SH3 Domain: Analysis of the Early Stages of Fibril Formation Fulltext Access 16 Pages 2006
Extended Flexible Linker Structures in the Complement Chimaeric Conjugate CR2-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy Fulltext Access 16 Pages 2006
Phage Display Reveals Multiple Contact Sites between FhuA, an Outer Membrane Receptor of Escherichia coli, and TonB † Fulltext Access 16 Pages 2006
Exploring Transcription Factor Binding Properties of Several Non-coding DNA Sequence Elements in the Human NF-IL6 Gene Fulltext Access 16 Pages 2006
Multi-step Assembly Pathway of the cbb3-type Cytochrome c Oxidase Complex Fulltext Access 16 Pages 2006
DNA Binding Domains and Nuclear Localization Signal of LEDGF: Contribution of two Helix-Turn-Helix (HTH)-like Domains and a Stretch of 58 Amino Acids of the N-terminal to the Trans-activation Potential of LEDGF Fulltext Access 16 Pages 2006
The ADAM metalloprotease Kuzbanian is crucial for proper heart formation in Drosophila melanogaster Fulltext Access 16 Pages 2006
A Molecular Dynamics Approach to the Structural Characterization of Amyloid Aggregation Fulltext Access 16 Pages 2006
Effects of Calcium Binding on the Side-chain Methyl Dynamics of Calbindin D9k: A 2H NMR Relaxation Study Fulltext Access 16 Pages 2006
Engineering of Large Numbers of Highly Specific Homing Endonucleases that Induce Recombination on Novel DNA Targets Fulltext Access 16 Pages 2006
Molecular Mechanisms of PKCα localization and Activation by Arachidonic Acid. The C2 Domain also Plays a Role Fulltext Access 16 Pages 2006
Three Key Residues Underlie the Differential Affinity of the TGFβ Isoforms for the TGFβ Type II Receptor Fulltext Access 16 Pages 2006
Uncoupling of RNA Binding and PKR Kinase Activation by Viral Inhibitor RNAs Fulltext Access 16 Pages 2006
Location of High and Low Affinity Fatty Acid Binding Sites on Human Serum Albumin Revealed by NMR Drug-competition Analysis Fulltext Access 16 Pages 2006
Methyl Substituents at the 11 or 12 Position of Retinal Profoundly and Differentially Affect Photochemistry and Signalling Activity of Rhodopsin Fulltext Access 16 Pages 2006
Downregulation of the LAR protein tyrosine phosphatase receptor is associated with increased dentate gyrus neurogenesis and an increased number of granule cell layer neurons Fulltext Access 16 Pages 2006
Upregulation of α-synuclein in neurons and glia in inflammatory demyelinating disease Fulltext Access 16 Pages 2006
An obligatory caravanserai stop on the silk road to neural induction: Inhibition of BMP/GDF signaling Fulltext Access 16 Pages 2006
The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease Fulltext Access 16 Pages 2006
The Human IgE-encoding Transcriptome to Assess Antibody Repertoires and Repertoire Evolution Fulltext Access 16 Pages 2006
Flexibility and Adaptability in Binding of E. coli Cytidine Repressor to Different Operators Suggests a Role in Differential Gene Regulation Fulltext Access 16 Pages 2006
Visualizing the Assembly of Human Rad51 Filaments on Double-stranded DNA Fulltext Access 16 Pages 2006
The Myosin Filament Superlattice in the Flight Muscles of Flies: A-band Lattice Optimisation for Stretch-activation? Fulltext Access 16 Pages 2006
Structural Basis of the Nickel Response in Helicobacter pylori: Crystal Structures of HpNikR in Apo and Nickel-bound States Fulltext Access 16 Pages 2006
Small Proteins Fold Through Transition States With Native-like Topologies Fulltext Access 16 Pages 2006
Unbound and Acylated Structures of the MecR1 Extracellular Antibiotic-sensor Domain Provide Insights into the Signal-transduction System that Triggers Methicillin Resistance Fulltext Access 16 Pages 2006
Sperm morphology in five species of cicadettine cicadas (Hemiptera: Cicadomorpha: Cicadidae) Fulltext Access 16 Pages 2006
Transmission Electron Microscopy Reveals an Optimal HIV-1 Nucleocapsid Aggregation with Single-stranded Nucleic Acids and the Mature HIV-1 Nucleocapsid Protein Fulltext Access 16 Pages 2006
Bi-directional control of motor neuron dendrite remodeling by the calcium permeability of AMPA receptors Fulltext Access 16 Pages 2006
Histidine Triad-like Motif of the Rotavirus NSP2 Octamer Mediates both RTPase and NTPase Activities Fulltext Access 16 Pages 2006
The effects of a dominant connexin32 mutant in myelinating Schwann cells Fulltext Access 16 Pages 2006
Structural Recognition between a Four-way DNA Junction and a Resolving Enzyme Fulltext Access 16 Pages 2006
Identification of the PXW Sequence as a Structural Gatekeeper of the Headpiece C-terminal Subdomain Fold Fulltext Access 16 Pages 2006
Activation profile of the F3/Contactin gene in the developing mouse cerebellum Fulltext Access 16 Pages 2006
The localization, trafficking and retrograde transport of BDNF bound to p75NTR in sympathetic neurons Fulltext Access 16 Pages 2006
Testicular zinc finger protein recruits histone deacetylase 2 and suppresses the transactivation function and intranuclear foci formation of agonist-bound androgen receptor competitively with TIF2 Fulltext Access 16 Pages 2006
RS5444, a novel PPARγ agonist, regulates aspects of the differentiated phenotype in nontransformed intestinal epithelial cells Fulltext Access 16 Pages 2006
Towards a Comprehensive Analysis of the Protein Phosphatase 1 Interactome in Drosophila Fulltext Access 17 Pages 2006
Evolution of myelin proteolipid proteins: Gene duplication in teleosts and expression pattern divergence Fulltext Access 17 Pages 2006
Characterization of novel splice variants of the PAC1 receptor in human neuroblastoma cells: Consequences for signaling by VIP and PACAP Fulltext Access 17 Pages 2006
Mitochondrial localization of CNP2 is regulated by phosphorylation of the N-terminal targeting signal by PKC: Implications of a mitochondrial function for CNP2 in glial and non-glial cells Fulltext Access 17 Pages 2006
Integrin-linked kinase regulates Bergmann glial differentiation during cerebellar development Fulltext Access 17 Pages 2006
Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome Fulltext Access 17 Pages 2006
Probing Nature’s Knots: The Folding Pathway of a Knotted Homodimeric Protein Fulltext Access 17 Pages 2006
Solution NMR Structure of the Junction between Tropomyosin Molecules: Implications for Actin Binding and Regulation Fulltext Access 17 Pages 2006
Structure of Aart, a Designed Six-finger Zinc Finger Peptide, Bound to DNA Fulltext Access 17 Pages 2006
Molecular Details of cAMP Generation in Mammalian Cells: A Tale of Two Systems Fulltext Access 17 Pages 2006
Binding Site Structure of One LRP–RAP Complex:Implications for a Common Ligand–Receptor Binding Motif Fulltext Access 17 Pages 2006
Electron Tomography of Swollen Rigor Fibers of Insect Flight Muscle Reveals a Short and Variably Angled S2 Domain Fulltext Access 17 Pages 2006
The Folding Energy Landscape of the Dimerization Domain of Escherichia coli Trp Repressor: A Joint Experimental and Theoretical Investigation Fulltext Access 17 Pages 2006
In Silico Approaches Reveal the Potential for DNA Sequence-dependent Histone Octamer Affinity to Influence Chromatin Structure in Vivo Fulltext Access 17 Pages 2006
Crystal Structures of Mouse 17α-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17α-reductive Activity of this Enzyme Fulltext Access 17 Pages 2006
Structural Determinants of Natriuretic Peptide Receptor Specificity and Degeneracy Fulltext Access 17 Pages 2006
Sequence Dependence of BNIP3 Transmembrane Domain Dimerization Implicates Side-chain Hydrogen Bonding and a Tandem GxxxG Motif in Specific Helix–Helix Interactions Fulltext Access 17 Pages 2006
New Peptide Inhibitors of Type IB Topoisomerases: Similarities and Differences Vis-a-vis Inhibitors of Tyrosine Recombinases Fulltext Access 17 Pages 2006
A Framework for Describing Topological Frustration in Models of Protein Folding Fulltext Access 17 Pages 2006
High-resolution Structures of Escherichia coli cDsbD in Different Redox States: A Combined Crystallographic, Biochemical and Computational Study Fulltext Access 17 Pages 2006
Φ-Analysis at the Experimental Limits: Mechanism of β-Hairpin Formation Fulltext Access 17 Pages 2006
Origins of Sequence Selectivity in Homologous Genetic Recombination: Insights from Rapid Kinetic Probing of RecA-mediated DNA Strand Exchange Fulltext Access 17 Pages 2006
Molecular Dissection of the Inhibitor Binding Pocket of Mitotic Kinesin Eg5 Reveals Mutants that Confer Resistance to Antimitotic Agents Fulltext Access 17 Pages 2006
Structures of in Vitro Evolved Binding Sites on Neocarzinostatin Scaffold Reveal Unanticipated Evolutionary Pathways Fulltext Access 17 Pages 2006
Polymorphism and Ultrastructural Organization of Prion Protein Amyloid Fibrils: An Insight from High Resolution Atomic Force Microscopy Fulltext Access 17 Pages 2006
Correlations between Scaffold/Matrix Attachment Region (S/MAR) Binding Activity and DNA Duplex Destabilization Energy Fulltext Access 17 Pages 2006
Crystallographic Structure of Human β-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of GM2 Ganglioside Hydrolysis Fulltext Access 17 Pages 2006
1.6 Å Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed Fulltext Access 17 Pages 2006
β-Propeller Crystal Structure of Psathyrella velutina Lectin: An Integrin-like Fungal Protein Interacting with Monosaccharides and Calcium Fulltext Access 17 Pages 2006
Indirect Readout of DNA Sequence by Papillomavirus E2 Proteins Depends Upon Net Cation Uptake Fulltext Access 17 Pages 2006
Solution Structure of a Zap1 Zinc-responsive Domain Provides Insights into Metalloregulatory Transcriptional Repression in Saccharomyces cerevisiae Fulltext Access 17 Pages 2006