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Molecular Biology Research Articles

Peptide growth factors signal differentially through protein kinase C to extracellular signal-regulated kinases in neonatal cardiomyocytes
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Sequence comparison and protein structure prediction
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DNA architecture: from G to Z
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Development and optimization of a Q-RT PCR method to quantify CYP19 mRNA expression in testis of male adult Xenopus laevis: Comparisons with aromatase enzyme activity
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Cloning and characterization of vitellogenin cDNA from the common Japanese conger (Conger myriaster) and vitellogenin gene expression during ovarian development
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N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways
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Regulation of FasL expression: A SH3 domain containing protein family involved in the lysosomal association of FasL
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Induction of cytosolic phospholipase A2 by lipopolysaccharide in canine tracheal smooth muscle cells: Involvement of MAPKs and NF-κB pathways
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G protein βγ11 complex translocation is induced by Gi, Gq and Gs coupling receptors and is regulated by the α subunit type
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The Src Homology 2-Containing Inositol 5-Phosphatase 1 (SHIP1) is involved in CD32a signaling in human neutrophils
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Clozapine, a neuroleptic agent, inhibits Akt by counteracting Ca2+/calmodulin in PTEN-negative U-87MG human glioblastoma cells
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The N-terminus of PKR is responsible for the activation of the NF-κB signaling pathway by interacting with the IKK complex
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c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells
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Comparative genomics and structural biology of the molecular innovations of eukaryotes
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Insulin rapidly upregulates protein kinase Cδ gene expression in skeletal muscle
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Opioid elevation of intracellular free calcium: Possible mechanisms and physiological relevance
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Novel function of POSH, a JNK scaffold, as an E3 ubiquitin ligase for the Hrs stability on early endosomes
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PI 3 kinase-dependent Akt kinase and PKCε independently regulate interferon-γ-induced STAT1α serine phosphorylation to induce monocyte chemotactic protein-1 expression
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Physiological levels of PTEN control the size of the cellular Ins(1,3,4,5,6)P5 pool
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The anti-proliferative effect of neurokinin-A on hematopoietic progenitor cells is partly mediated by p53 activating the 5′ flanking region of neurokinin-2 receptor
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Prostacyclin receptor induces STAT1 and STAT3 phosphorylations in human erythroleukemia cells: A mechanism requiring PTX-insensitive G proteins, ERK and JNK
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Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide
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α2-Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR
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Serine phosphorylation differentially affects RhoA binding to effectors: Implications to NGF-induced neurite outgrowth
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LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain
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Trapping of DNA topoisomerase I on nick-containing DNA in cell free extracts of Saccharomyces cerevisiae
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Attenuated secretion of very low density lipoproteins from McA-RH7777 cells treated with eicosapentaenoic acid is associated with impaired utilization of triacylglycerol synthesized via phospholipid remodeling
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Screening for soluble expression constructs using cell-free protein synthesis
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Evaluation of two novel tag-based labelling technologies for site-specific modification of proteins
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Changes in cell wall composition associated with maturation in the gymnosperm Araucaria angustifolia
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Formation of hMSH4–hMSH5 heterocomplex is a prerequisite for subsequent GPS2 recruitment
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Esc4/Rtt107 and the control of recombination during replication
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Cellular responses to DNA damage: Current state of the field and review of the 52nd Benzon Symposium
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RecB-dependent mutator phenotype in Neisseria meningitidis strains naturally defective in mismatch repair
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Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis–trans epimerization
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DNA repair: From molecular mechanism to human disease
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Identification of MMS19 domains with distinct functions in NER and transcription
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Ntg1p, the base excision repair protein, generates mutagenic intermediates in yeast mitochondrial DNA
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TRB3 is a PI 3-kinase dependent indicator for nutrient starvation
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Identification of a novel motif in DNA ligases exemplified by DNA ligase IV
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Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function
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Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae
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Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation
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Studies on chromosome aberration induction: What can they tell us about DNA repair?
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Telomeres and chromosome instability
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Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae
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Multiple solutions to inefficient lesion bypass by T7 DNA polymerase
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High-resolution protein–protein docking
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Model systems for β-hairpins and β-sheets
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Viral enzymes
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Gangliosides of the stroma layer participate in the interferon-gamma receptor-dependent controls of myelopoiesis
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Pex14p, more than just a docking protein
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Proteomics of the peroxisome
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The biochemistry of oleate induction: Transcriptional upregulation and peroxisome proliferation
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Phosphorylation regulates mitochondrial glycerol-3-phosphate-1 acyltransferase activity in T-lymphocytes
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Triacylglycerol accumulation is not primarily affected in myotubes established from type 2 diabetic subjects
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Plant fatty acid (ethanol) amide hydrolases
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Phospholipid homeostasis in phosphatidylserine synthase-2-deficient mice
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Alkaline sphingomyelinase: An old enzyme with novel implications
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Sphingolipids of the nucleus and their role in nuclear signaling
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Completing the cycles; the dynamics of endonuclear lipidomics
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Arabidopsis thaliana expresses two functional isoforms of Arvp, a protein involved in the regulation of cellular lipid homeostasis
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Overexpression of SND p102, a rat homologue of p100 coactivator, promotes the secretion of lipoprotein phospholipids in primary hepatocytes
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Cytoplasmic Ca2+ signals and cellular death by apoptosis in myocardiac H9c2 cells
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Live cell imaging of phosphoinositide dynamics with fluorescent protein domains
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C1 domains exposed: From diacylglycerol binding to protein–protein interactions
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Enzymatic oxidation of dipyridamole in homogeneous and micellar solutions in the horseradish peroxidase–hydrogen peroxide system
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N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring
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Evaluation of the dietary effects of coenzyme Q in vivo by the oxidative stress marker, hydroxyoctadecadienoic acid and its stereoisomer ratio
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Carbohydrates as future anti-adhesion drugs for infectious diseases
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An ascorbate-reducible cytochrome b561 is localized in macrophage lysosomes
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Glutamine synthetase degradation is controlled by oxidative proteolysis in the marine cyanobacterium Prochlorococcus marinus strain PCC 9511
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Involvement of the AtoS-AtoC signal transduction system in poly-(R)-3-hydroxybutyrate biosynthesis in Escherichia coli
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Location and characterization of the O-GlcNAcase active site
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Biochemical limitations to high-level expression of humanized monoclonal antibodies in transgenic maize seed endosperm
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Transcriptional activation of c-Fos by constitutively active Gα16QL through a STAT1-dependent pathway
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Csk homologous kinase (CHK), unlike Csk, enhances MAPK activation via Ras-mediated signaling in a Src-independent manner
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Inducible phosphorylation of cortactin is not necessary for cortactin-mediated actin polymerisation
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Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E
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Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells
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The effect of RGS12 on PDGFβ receptor signalling to p42/p44 mitogen activated protein kinase in mammalian cells
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Signaling through ERBB receptors: Multiple layers of diversity and control
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G protein βγ complex translocation from plasma membrane to Golgi complex is influenced by receptor γ subunit interaction
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TRIP6 transcriptional co-activator is a novel substrate of AMP-activated protein kinase
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TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD
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Biosynthesis and trafficking of seven transmembrane receptor signalling complexes
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RET oncoproteins induce tyrosine phosphorylation changes of proteins involved in RNA metabolism
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RGS2 promotes formation of neurites by stimulating microtubule polymerization
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Characterization of prmt7α and β isozymes from Chinese hamster cells sensitive and resistant to topoisomerase II inhibitors
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Hsp78 chaperone functions in restoration of mitochondrial network following heat stress
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Shared components of mitochondrial and peroxisomal division
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Hereditary hemochromatosis
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Characterization of a mutation and an alternative splicing of UDP-galactose transporter in MDCK-RCAr cell line
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Gene expression analysis of ELF-MF exposed human monocytes indicating the involvement of the alternative activation pathway
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Systematic search for the rate constants that control the exocytotic process from chromaffin cells by a Genetic Algorithm
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PI 4,5-P2 stimulates glucose transport activity of GLUT4 in the plasma membrane of 3T3-L1 adipocytes
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The 3′-untranslated region directs ribosomal protein-encoding mRNAs to specific cytoplasmic regions
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Toxicity of enzymatic oxidation products of spermine to human melanoma cells (M14): Sensitization by heat and MDL 72527
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Evaluation of IFN-γ effects on apoptosis and gene expression in neuroblastoma—Preclinical studies
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Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis
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