VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue probiotics and gluten intolerance Fulltext Access 14 Pages 2006
Linear and nonlinear QSAR study of N-hydroxy-2-[(phenylsulfonyl)amino]acetamide derivatives as matrix metalloproteinase inhibitors Fulltext Access 14 Pages 2006
Recent developments in the identification of novel oxazolidinone antibacterial agents Fulltext Access 14 Pages 2006
Conformationally restrained carbazolone-containing α,γ-diketo acids as inhibitors of HIV integrase Fulltext Access 14 Pages 2006
New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies Fulltext Access 14 Pages 2006
Design, synthesis, and biological testing of potential heme-coordinating nitric oxide synthase inhibitors Fulltext Access 14 Pages 2006
Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents Fulltext Access 14 Pages 2006
Structure–activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors Fulltext Access 14 Pages 2006
Characterizing pathogenic processes in Batten disease: Use of small eukaryotic model systems Fulltext Access 14 Pages 2006
Functional biology of the neuronal ceroid lipofuscinoses (NCL) proteins Fulltext Access 14 Pages 2006
Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) oligonucleotide incorporating 7-deazaguanine bases Fulltext Access 14 Pages 2006
Tropomyosin and caldesmon regulate cytokinesis speed and membrane stability during cell division Fulltext Access 14 Pages 2006
A conserved molecular action of native and recombinant Epap-1 in inhibition of HIV-1 gp120 mediated viral entry Fulltext Access 14 Pages 2006
The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases Fulltext Access 14 Pages 2006
Expression and characterization of a functional canine variant of cytochrome b5 reductase ★ Fulltext Access 14 Pages 2006
Studies on genomic DNA topology and stability in brain regions of Parkinson’s disease Fulltext Access 14 Pages 2006
Stereochemistry and deuterium isotope effects associated with the cyclization-rearrangements catalyzed by tobacco epiaristolochene and hyoscyamus premnaspirodiene synthases, and the chimeric CH4 hybrid cyclase Fulltext Access 14 Pages 2006
Structure–activity relationship of an α-toxin Bs-Tx28 from scorpion (Buthus sindicus) venom suggests a new α-toxin subfamily Fulltext Access 14 Pages 2006
A novel siRNA validation system for functional screening and identification of effective RNAi probes in mammalian cells Fulltext Access 14 Pages 2006
Expression profiling of muscles from Fukuyama-type congenital muscular dystrophy and laminin-α2 deficient congenital muscular dystrophy; is congenital muscular dystrophy a primary fibrotic disease? Fulltext Access 14 Pages 2006
Using solid-state 31P{19F} REDOR NMR to measure distances between a trifluoromethyl group and a phosphodiester in nucleic acids Fulltext Access 14 Pages 2006
EasySpin, a comprehensive software package for spectral simulation and analysis in EPR Fulltext Access 14 Pages 2006
Evaluation of glycolamide esters of indomethacin as potential cyclooxygenase-2 (COX-2) inhibitors Fulltext Access 14 Pages 2006
The discovery of glycine and related amino acid-based factor Xa inhibitors Fulltext Access 14 Pages 2006
On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases Fulltext Access 14 Pages 2006
Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: Potential agents for photodynamic therapy of cancers Fulltext Access 14 Pages 2006
3D-QSAR studies on tripeptide aldehyde inhibitors of proteasome using CoMFA and CoMSIA methods Fulltext Access 14 Pages 2006
3D QSAR study of hypolipidemic asarones by comparative molecular surface analysis Fulltext Access 14 Pages 2006
1-Benzyl-1,2,3,4-tetrahydroisoquinoline-6,7-diols as novel affinity and photoaffinity probes for β-adrenoceptor subtypes Fulltext Access 14 Pages 2006
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives Fulltext Access 14 Pages 2006
Synthesis and structure–activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity Fulltext Access 14 Pages 2006
Quantitative structure–activity relationships for small non-peptide antagonists of CXCR2: Indirect 3D approach using the frontal polygon method Fulltext Access 14 Pages 2006
Serotype-selective, small-molecule inhibitors of the zinc endopeptidase of botulinum neurotoxin serotype A Fulltext Access 14 Pages 2006
Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents Fulltext Access 14 Pages 2006
A credit-card library approach for disrupting protein–protein interactions Fulltext Access 14 Pages 2006
Effect of alkyl groups on the cellular hydrolysis of stavudine phosphoramidates Fulltext Access 14 Pages 2006
Synthesis of three classes of rhodacyanine dyes and evaluation of their in vitro and in vivo antimalarial activity Fulltext Access 14 Pages 2006
Design, synthesis, and preliminary SAR study of 3- and 6-side-chain-extended tetrahydro-pyran analogues of cis- and trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine Fulltext Access 14 Pages 2006
Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity Fulltext Access 14 Pages 2006
Synthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles Fulltext Access 14 Pages 2006
Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCβ-selective inhibitors Fulltext Access 14 Pages 2006
Diversity-oriented chemical modification of heparin: Identification of charge-reduced N-acyl heparin derivatives having increased selectivity for heparin-binding proteins Fulltext Access 14 Pages 2006
Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors Fulltext Access 14 Pages 2006
Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation Fulltext Access 14 Pages 2006
Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity Fulltext Access 14 Pages 2006
Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer Fulltext Access 14 Pages 2006
Antagonists of the myelin-associated glycoprotein: A new class of tetrasaccharide mimics Fulltext Access 14 Pages 2006
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs Fulltext Access 14 Pages 2006
Approaches to the isolation and characterization of molecular chaperones Fulltext Access 15 Pages 2006
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function Fulltext Access 15 Pages 2006
Nitric oxide synthase regulation and diversity: Implications in Parkinson’s disease Fulltext Access 15 Pages 2006
Characterization of the AMP-activated protein kinase pathway in chickens Fulltext Access 15 Pages 2006
Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation Fulltext Access 15 Pages 2006
Double-strand break repair in bacteriophage T4: Coordination of DNA ends and effects of mutations in recombinational genes Fulltext Access 15 Pages 2006
Truncation of the C-terminus of human MLH1 blocks intracellular stabilization of PMS2 and disrupts DNA mismatch repair Fulltext Access 15 Pages 2006
Palindromes and genomic stress fractures: Bracing and repairing the damage Fulltext Access 15 Pages 2006
Inflammation-associated immune suppression in cancer: The roles played by cytokines, chemokines and additional mediators Fulltext Access 15 Pages 2006
Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain Fulltext Access 15 Pages 2006
Recent Expansion of the Telomeric Complex in Rodents: Two Distinct POT1 Proteins Protect Mouse Telomeres Fulltext Access 15 Pages 2006
Parafibromin/Hyrax Activates Wnt/Wg Target Gene Transcription by Direct Association with β-catenin/Armadillo Fulltext Access 15 Pages 2006
Cyclosporin A binding to Mycobacterium tuberculosis peptidyl-prolyl cis-trans isomerase A - Investigation by CD, FTIR and fluorescence spectroscopy Fulltext Access 15 Pages 2006
Dynamics of paramagnetic agents by off-resonance rotating frame technique Fulltext Access 15 Pages 2006
Using a cross-coil to reduce RF heating by an order of magnitude in triple-resonance multinuclear MAS at high fields Fulltext Access 15 Pages 2006
Efficient orientational averaging by the extension of Lebedev grids via regularized octahedral symmetry expansion Fulltext Access 15 Pages 2006
Magnetization-recovery experiments for static and MAS-NMR of IÂ =Â 3/2 nuclei Fulltext Access 15 Pages 2006
Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation Fulltext Access 15 Pages 2006
A DOQSY approach for the elucidation of torsion angle distributions in biopolymers: Application to silk Fulltext Access 15 Pages 2006
Mammalian expression of full-length bovine aggrecan and link protein: Formation of recombinant proteoglycan aggregates and analysis of proteolytic cleavage by ADAMTS-4 and MMP-13 Fulltext Access 15 Pages 2006
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis Fulltext Access 15 Pages 2006
Visualizing common deletion of mitochondrial DNA-augmented mitochondrial reactive oxygen species generation and apoptosis upon oxidative stress Fulltext Access 15 Pages 2006
Restoration of native folding of single-stranded DNA sequences through reverse mutations: An indication of a new epigenetic mechanism Fulltext Access 15 Pages 2006
Heteroactivator effects on the coupling and spin state equilibrium of CYP2C9 Fulltext Access 15 Pages 2006
Integrative analysis of transcript and metabolite profiling data sets to evaluate the regulation of biochemical pathways during photomorphogenesis Fulltext Access 15 Pages 2006
Measurement of protein turnover rates by heavy water labeling of nonessential amino acids Fulltext Access 15 Pages 2006
Branching mode in complex-type triantennary N-glycans as regulatory element of their ligand properties Fulltext Access 15 Pages 2006
Cloning and expression of insulin-like growth factors I and II in the shi drum (Umbrina cirrosa) Fulltext Access 15 Pages 2006
Susceptibility to cholesterol gallstone formation: Evidence that LITH genes also encode immune-related factors Fulltext Access 15 Pages 2006
Cardiac cell death in early diabetes and its modulation by dietary fatty acids Fulltext Access 15 Pages 2006
Promoter analysis of the murine squalene epoxidase gene. Identification of a 205 bp homing region regulated by both SREBP'S and NF-Y Fulltext Access 15 Pages 2006
Plant peroxisomes respire in the light: Some gaps of the photorespiratory C2 cycle have become filled—Others remain Fulltext Access 15 Pages 2006
Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3 Fulltext Access 15 Pages 2006
Evolutionary genetics of juvenile hormone and ecdysteroid regulation in Gryllus: A case study in the microevolution of endocrine regulation Fulltext Access 15 Pages 2006
In vitro effects of insulin-like growth factors and insulin on oocyte maturation and maturation-inducing steroid production in ovarian follicles of common carp, Cyprinus carpio Fulltext Access 15 Pages 2006