Dimerisation and an Increase in Active Site Aromatic Groups as Adaptations to High Temperatures: X-ray Solution Scattering and Substrate-bound Crystal Structures of Rhodothermus marinus Endoglucanase Cel12A Fulltext Access 15 Pages 2006
Effects of Solubilization on the Structure and Function of the Sensory Rhodopsin II/Transducer Complex Fulltext Access 15 Pages 2006
The Solution Structure of the Native K50 Bicoid Homeodomain Bound to the Consensus TAATCC DNA-binding Site Fulltext Access 15 Pages 2006
Structural Basis of the Differential Stability and Receptor Specificity of H-2Db in Complex with Murine versus Human β2-Microglobulin Fulltext Access 15 Pages 2006
Crystal Structure of a Glycyl Radical Enzyme from Archaeoglobus fulgidus Fulltext Access 15 Pages 2006
X-ray Structures of Free and Leupeptin-complexed Human αI-Tryptase Mutants: Indication for an α→β-Tryptase Transition Fulltext Access 15 Pages 2006
Tyrosine Plays a Dominant Functional Role in the Paratope of a Synthetic Antibody Derived from a Four Amino Acid Code Fulltext Access 15 Pages 2006
The Disaggregation Activity of the Mitochondrial ClpB Homolog Hsp78 Maintains Hsp70 Function during Heat Stress Fulltext Access 15 Pages 2006
Translation of Sindbis Virus 26 S mRNA Does Not Require Intact Eukariotic Initiation Factor 4G Fulltext Access 15 Pages 2006
Cytoplasmic Shuttling of Protons in Anabaena Sensory Rhodopsin: Implications for Signaling Mechanism Fulltext Access 15 Pages 2006
Structural Basis for the Substrate Specificity of a Bacillus 1,3-1,4-β-Glucanase Fulltext Access 15 Pages 2006
Structural Basis for the Requirement of Two Phosphotyrosine Residues in Signaling Mediated by Syk Tyrosine Kinase Fulltext Access 15 Pages 2006
Molecular Dynamics Simulations and Free Energy Analyses on the Dimer Formation of an Amyloidogenic Heptapeptide from Human β2-Microglobulin: Implication for the Protofibril Structure Fulltext Access 15 Pages 2006
Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 Fulltext Access 15 Pages 2006
Selective Pressures at a Codon-level Predict Deleterious Mutations in Human Disease Genes Fulltext Access 15 Pages 2006
A Novel Processive Mechanism for DNA Synthesis Revealed by Structure, Modeling and Mutagenesis of the Accessory Subunit of Human Mitochondrial DNA Polymerase Fulltext Access 15 Pages 2006
Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine Fulltext Access 15 Pages 2006
TCP34, a Nuclear-encoded Response Regulator-like TPR Protein of Higher Plant Chloroplasts Fulltext Access 15 Pages 2006
Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution Fulltext Access 15 Pages 2006
On the Mechanism of Sequence-specific DNA-dependent Acetylation of p53: The Acetylation Motif is Exposed upon DNA Binding Fulltext Access 15 Pages 2006
Direct Selection of Antibodies from Complex Libraries with the Protein Fragment Complementation Assay Fulltext Access 15 Pages 2006
Detecting Molecular Interactions that Stabilize Native Bovine Rhodopsin Fulltext Access 15 Pages 2006
Up-regulation and increased phosphorylation of protein kinase C (PKC) δ, μ and θ in the degenerating rd1 mouse retina Fulltext Access 15 Pages 2006
Determinants of Exon 7 Splicing in the Spinal Muscular Atrophy Genes, SMN1 and SMN2 Fulltext Access 15 Pages 2006
Powerful Multilocus Tests of Genetic Association in the Presence of Gene-Gene and Gene-Environment Interactions Fulltext Access 15 Pages 2006
Meiotic Recombination and Spatial Proximity in the Etiology of the Recurrent t(11;22) Fulltext Access 15 Pages 2006
Trait Components Provide Tools to Dissect the Genetic Susceptibility of Migraine Fulltext Access 15 Pages 2006
Reconstruction of a Functional Human Gene Network, with an Application for Prioritizing Positional Candidate Genes Fulltext Access 15 Pages 2006
Diplotype Trend Regression Analysis of the ADH Gene Cluster and the ALDH2 Gene: Multiple Significant Associations with Alcohol Dependence Fulltext Access 15 Pages 2006
Generalized Genomic Distance–Based Regression Methodology for Multilocus Association Analysis Fulltext Access 15 Pages 2006
Inflammatory leukocytes and iron turnover in experimental hemorrhagic lung trauma Fulltext Access 15 Pages 2006
Labeled lines in the retinotectal system: Markers for retinorecipient sublaminae and the retinal ganglion cell subsets that innervate them Fulltext Access 15 Pages 2006
Brain-derived neurotrophic factor-induced potentiation of glutamate and GABA release: Different dependency on signaling pathways and neuronal activity Fulltext Access 15 Pages 2006
Synaptic activity and F-actin coordinately regulate CaMKIIα localization to dendritic postsynaptic sites in developing hippocampal slices Fulltext Access 15 Pages 2006
Channel Opening Motion of α7 Nicotinic Acetylcholine Receptor as Suggested by Normal Mode Analysis Fulltext Access 15 Pages 2006
Brain-specific factors in combination with mutant huntingtin induce gene-specific transcriptional dysregulation Fulltext Access 15 Pages 2006
Unraveling the differential expression of the two isoforms of myelin-associated glycoprotein in a mouse expressing GFP-tagged S-MAG specifically regulated and targeted into the different myelin compartments Fulltext Access 15 Pages 2006
A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex Fulltext Access 15 Pages 2006
GSK3β and PKCζ function in centrosome localization and process stabilization during Slit-mediated neuronal repolarization Fulltext Access 15 Pages 2006
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cord Fulltext Access 15 Pages 2006
Mechanism of the Frank–Starling law—A simulation study with a novel cardiac muscle contraction model that includes titin and troponin I Fulltext Access 15 Pages 2006
Heart estrogen receptor alpha: Distinct membrane and nuclear distribution patterns and regulation by estrogen Fulltext Access 15 Pages 2006
Differential gene expression profiling in genetic and multifactorial cardiovascular diseases Fulltext Access 15 Pages 2006
Actin Interacts with CCT via Discrete Binding Sites: A Binding transition-release Model for CCT-Mediated Actin Folding Fulltext Access 15 Pages 2006
Epitope Diversity of Hepatitis B Virus Capsids: Quasi-equivalent Variations in Spike Epitopes and Binding of Different Antibodies to the same Epitope Fulltext Access 15 Pages 2006
The Syk tyrosine kinase: A new negative regulator in tumor growth and progression Fulltext Access 15 Pages 2006
SAGE reveals expression of Wnt signalling pathway members during mouse prostate development Fulltext Access 15 Pages 2006
Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii Fulltext Access 15 Pages 2006
A complex gene cluster for indole-diterpene biosynthesis in the grass endophyte Neotyphodium lolii Fulltext Access 15 Pages 2006
Cloning and characterization of the erg1 gene of Trichoderma harzianum: Effect of the erg1 silencing on ergosterol biosynthesis and resistance to terbinafine Fulltext Access 15 Pages 2006
Biogenesis and replication of small plasmid-like derivatives of the mitochondrial DNA in Neurospora crassa Fulltext Access 15 Pages 2006
Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3′-indolyl)methane (DIM) and 5,5′-dibromoDIM Fulltext Access 15 Pages 2006
L1 on ovarian carcinoma cells is a binding partner for Neuropilin-1 on mesothelial cells Fulltext Access 15 Pages 2006
Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells Fulltext Access 15 Pages 2006
Mass spectrometric identification of serine hydrolase OVCA2 in the medulloblastoma cell line DAOY Fulltext Access 15 Pages 2006
Gene expression in the LNCaP human prostate cancer progression model: Progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo Fulltext Access 15 Pages 2006
National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report Fulltext Access 15 Pages 2006
Role of Naturally Arising Regulatory T Cells in Hematopoietic Cell Transplantation Fulltext Access 15 Pages 2006
Measuring Therapeutic Response in Chronic Graft-versus-Host Disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. Response Criteria Working Group Report Fulltext Access 15 Pages 2006
Severe Infections after Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation in Adults: Comparison of Cord Blood Transplantation with Peripheral Blood and Bone Marrow Transplantation Fulltext Access 15 Pages 2006
Characterization of Cord Blood Natural Killer and Lymphokine Activated Killer Lymphocytes Following Ex Vivo Cellular Engineering Fulltext Access 15 Pages 2006
Differences between left and right ventricular anatomy determine the types of reentrant circuits induced by an external electric shock. A rabbit heart simulation study Fulltext Access 15 Pages 2006
Φ-Analysis of the Folding of the B Domain of Protein A Using Multiple Optical Probes Fulltext Access 15 Pages 2006
Archaeal RNA Polymerase is Sensitive to Intrinsic Termination Directed by Transcribed and Remote Sequences Fulltext Access 15 Pages 2006
I-BasI and I-HmuI: Two Phage Intron-encoded Endonucleases with Homologous DNA Recognition Sequences but Distinct DNA Specificities Fulltext Access 15 Pages 2006
The Chemotaxis Response Regulator CheY Can Catalyze its Own Acetylation Fulltext Access 15 Pages 2006
Thermodynamic and Kinetic Characterization of Ligand Binding to the Purine Riboswitch Aptamer Domain Fulltext Access 15 Pages 2006
Structural Snapshots of β-1,4-Galactosyltransferase-I Along the Kinetic Pathway Fulltext Access 15 Pages 2006
Communication Between Accessory Factors and the Cre Recombinase at Hybrid psi-loxP sites Fulltext Access 15 Pages 2006
The Folding Pathway of Spectrin R17 from Experiment and Simulation: Using Experimentally Validated MD Simulations to Characterize States Hinted at by Experiment Fulltext Access 15 Pages 2006
Crystal Structures of the Lytic Transglycosylase MltA from N. gonorrhoeae and E. coli: Insights into Interdomain Movements and Substrate Binding Fulltext Access 15 Pages 2006
Comprehensive Analysis of Combinatorial Regulation using the Transcriptional Regulatory Network of Yeast Fulltext Access 15 Pages 2006
Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis Fulltext Access 15 Pages 2006
Assembly of Infectious HIV-1 in Human Epithelial and T-Lymphoblastic Cell Lines Fulltext Access 15 Pages 2006
Mitochondrial disease activates transcripts of the unfolded protein response and cell cycle and inhibits vesicular secretion and oligodendrocyte-specific transcripts Fulltext Access 15 Pages 2006
Dynamics of Mutation and Recombination in a Replicating Population of Complementing, Defective Viral Genomes Fulltext Access 15 Pages 2006
Transcriptional Repressor CcpN from Bacillus subtilis Compensates Asymmetric Contact Distribution by Cooperative Binding Fulltext Access 15 Pages 2006
Evaluation of Energetic and Dynamic Coupling Networks in a PDZ Domain Protein Fulltext Access 15 Pages 2006
Functional and Structural Characterization of HIV-1 gp41 Ectodomain Regions in Phospholipid Membranes Suggests that the Fusion-active Conformation Is Extended Fulltext Access 15 Pages 2006
Characterization of MobR, the 3-Hydroxybenzoate-responsive Transcriptional Regulator for the 3-Hydroxybenzoate Hydroxylase Gene of Comamonas testosteroni KH122-3s Fulltext Access 15 Pages 2006
Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists Fulltext Access 15 Pages 2006
A Dimeric Kinase Assembly Underlying Autophosphorylation in the p21 Activated Kinases Fulltext Access 15 Pages 2006
In Vitro and in Vivo Nucleosome Positioning on the Ovine β-Lactoglobulin Gene Are Related Fulltext Access 15 Pages 2006
Three-dimensional Structure of a Type III Glutamine Synthetase by Single-particle Reconstruction Fulltext Access 15 Pages 2006
Characterization of big bang, a novel gene encoding for PDZ domain-containing proteins that are dynamically expressed throughout Drosophila development Fulltext Access 15 Pages 2006