Four-base codon/anticodon strategy and non-enzymatic aminoacylation for protein engineering with non-natural amino acids Fulltext Access 9 Pages 2005
Expression and characterization of N-terminal domain of Epstein-Barr virus latent membrane protein 2A in Escherichia coli Fulltext Access 9 Pages 2005
Expression, purification, and characterization of recombinant human flotillin-1 in Escherichia coli Fulltext Access 9 Pages 2005
Improvement of the thermostability and catalytic activity of a mesophilic family 11 xylanase by N-terminus replacement Fulltext Access 9 Pages 2005
Cloning of thrombolytic enzyme (lumbrokinase) from earthworm and its expression in the yeast Pichia pastoris Fulltext Access 9 Pages 2005
Production of constitutively acetylated recombinant p53 from yeast and Escherichia coli by tethered catalysis Fulltext Access 9 Pages 2005
Purification and characterization of the creatine transporter expressed at high levels in HEK293 cells Fulltext Access 9 Pages 2005
Characterisation of tyrosine-phosphorylation-defective calmodulin mutants Fulltext Access 9 Pages 2005
Preparation of recombinant thioredoxin fused N-terminal proCNP: Analysis of enterokinase cleavage products reveals new enterokinase cleavage sites Fulltext Access 9 Pages 2005
Purification and characterization of recombinant human antithrombin containing the prelatent form in Chinese hamster ovary cells Fulltext Access 9 Pages 2005
Construction and characterization of Pichia pastoris strains for labeling aromatic amino acids in recombinant proteins Fulltext Access 9 Pages 2005
The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress Fulltext Access 9 Pages 2005
Overexpression of human alanine:glyoxylate aminotransferase in Escherichia coli: renaturation from guanidine-HCl and affinity for pyridoxal phosphate co-factor Fulltext Access 9 Pages 2005
Reconstitution of eukaryotic translation elongation in vitro following initiation by internal ribosomal entry Fulltext Access 9 Pages 2005
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation Fulltext Access 9 Pages 2005
Pore formation in and enlargement of phospholipid liposomes by synthetic models of ceramides and sphingomyelin Fulltext Access 9 Pages 2005
QSAR studies on some thiophene analogs as anti-inflammatory agents: enhancement of activity by electronic parameters and its utilization for chemical lead optimization Fulltext Access 9 Pages 2005
Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers Fulltext Access 9 Pages 2005
Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues Fulltext Access 9 Pages 2005
Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin Fulltext Access 9 Pages 2005
Design and development of a fluorescent probe for monitoring hydrogen peroxide using photoinduced electron transfer Fulltext Access 9 Pages 2005
Molecular docking and 3D-QSAR studies of Yersinia protein tyrosine phosphatase YopH inhibitors Fulltext Access 9 Pages 2005
In vitro and in vivo imaging of cell migration: Two interdepending methods to unravel metastasis formation Fulltext Access 9 Pages 2005
Use of 11α-deuterium labeled cortisol as a tracer for assessing reduced 11β-HSD2 activity in vivo following glycyrrhetinic acid ingestion in a human subject Fulltext Access 9 Pages 2005
Cholinesterase inhibitory pregnane-type steroidal alkaloids from Sarcococca hookeriana Fulltext Access 9 Pages 2005
New glycosides of the campesterol derivative from the rhizomes of Tacca chantrieri Fulltext Access 9 Pages 2005
Gas chromatography-mass spectrometric analysis of oxidative reactions of [19,19-2H2]19-hydroxy-3-deoxy androgens by placental aromatase Fulltext Access 9 Pages 2005
C-25 epimeric 26-haloponasterone A: Synthesis, absolute configuration and moulting activity Fulltext Access 9 Pages 2005
Synthesis and in vitro cholesterol dissolution by 23- and 24-phosphonobile acids Fulltext Access 9 Pages 2005
Changes in RANKL/OPG/RANK gene expression in peripheral mononuclear cells following treatment with estrogen or raloxifene Fulltext Access 9 Pages 2005
Formation of the depurinating N3adenine and N7guanine adducts by reaction of DNA with hexestrol-3â²,4â²-quinone or enzyme-activated 3â²-hydroxyhexestrol Fulltext Access 9 Pages 2005
Side-chain-modified analogs of calcitriol cause resistance of human HL-60 promyelocytic leukemia cells to drug-induced apoptosis Fulltext Access 9 Pages 2005
Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment Fulltext Access 9 Pages 2005
Tissue homeostasis and the control of the neoplastic phenotype in epithelial cancers Fulltext Access 9 Pages 2005
Mechanistic study of proton transfer and hysteresis in catalytic antibody 16E7 by site-directed mutagenesis and homology modeling Fulltext Access 9 Pages 2005
3D-extravasation model - selection of highly motile and metastatic cancer cells Fulltext Access 9 Pages 2005
ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages Fulltext Access 9 Pages 2005
Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model Fulltext Access 9 Pages 2005
Emergence and prevention of resistance against small molecule inhibitors Fulltext Access 9 Pages 2005
Selective evolutionary pressure from the tissue microenvironment drives tumor progression Fulltext Access 9 Pages 2005
Purification and characterization of the recombinant arylsulfatase cloned from Pseudoalteromonas carrageenovora Fulltext Access 9 Pages 2005
Purification and characterization of a single-chain chimeric anti-p185 antibody expressed by CHO-GS system Fulltext Access 9 Pages 2005
Clp upregulates transcription of engA gene encoding a virulence factor in Xanthomonas campestris by direct binding to the upstream tandem Clp sites Fulltext Access 9 Pages 2005
Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1 Fulltext Access 9 Pages 2005
The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding Fulltext Access 9 Pages 2005
SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1 Fulltext Access 9 Pages 2005
Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV Fulltext Access 9 Pages 2005
The interplay between structure and function in intrinsically unstructured proteins Fulltext Access 9 Pages 2005
A novel neurotrophic role of secretory phospholipases A2 for cerebellar granule neurons Fulltext Access 9 Pages 2005
Evidence of differential pH regulation of the Arabidopsis vacuolar Ca2+/H+ antiporters CAX1 and CAX2 Fulltext Access 9 Pages 2005
Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation Fulltext Access 9 Pages 2005
Expression and functional characterization of LRRC4, a novel brain-specific member of the LRR superfamily Fulltext Access 9 Pages 2005
TNF-α enhances phenotypic and functional maturation of human epidermal Langerhans cells and induces IL-12 p40 and IP-10/CXCL-10 production Fulltext Access 9 Pages 2005
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays Fulltext Access 9 Pages 2005
Molecular characterization of the first satellite DNA with CENP-B and CDEIII motifs in the bat Pipistrellus kuhli Fulltext Access 9 Pages 2005
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells Fulltext Access 9 Pages 2005
The yeast osmosensitive mutant fps1Δ transformed by the cauliflower BobTIP1;1 aquaporin withstand a hypo-osmotic shock Fulltext Access 9 Pages 2005
ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells Fulltext Access 9 Pages 2005
Sensitivity of the Drosophila para sodium channel to DDT is not lowered by the super-kdr mutation M918T on the IIS4–S5 linker that profoundly reduces sensitivity to permethrin and deltamethrin Fulltext Access 9 Pages 2005
Immune cell-induced synthesis of NO and reactive oxygen species in lymphoma cells causes their death by apoptosis Fulltext Access 9 Pages 2005
High resolution crystal structures of human Rab4a in its active and inactive conformations Fulltext Access 9 Pages 2005
Modulating furin activity with designed mini-PDX peptides: Synthesis and in vitro kinetic evaluation Fulltext Access 9 Pages 2005
GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa Fulltext Access 9 Pages 2005
Chalcones as potent tyrosinase inhibitors: the importance of a 2,4-substituted resorcinol moiety Fulltext Access 9 Pages 2005
Efficient fluorescent sensors of oligopeptides by dithiobis(2-benzoylamide)-bridged bis(β-cyclodextrin)s: structure in solution, binding behavior, and thermodynamic origin Fulltext Access 9 Pages 2005
Effect of Chinese medicine alpinetin on the structure of human serum albumin Fulltext Access 9 Pages 2005
Substituted propanolamines and alkylamines derived from fluoxetine as potent appetite suppressants Fulltext Access 9 Pages 2005
Design, synthesis, and biological evaluation of (E)- and (Z)-styryl-2-acetoxyphenyl sulfides and sulfones as cyclooxygenase-2 inhibitors Fulltext Access 9 Pages 2005
Comparative molecular field analysis and comparative molecular similarity indices analysis of human thymidine kinase 1 substrates Fulltext Access 9 Pages 2005
Novel thiocoumarins as inhibitors of TNF-α induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation Fulltext Access 9 Pages 2005
α-Glucopyranoimidazolines as intermediate analogue inhibitors of family 20 β-N-acetylglucosaminidases Fulltext Access 9 Pages 2005
Annelated pyrrolo-pyrimidines from amino-cyanopyrroles and BMMAs as leads for new DNA-interactive ring systems Fulltext Access 9 Pages 2005
Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents Fulltext Access 9 Pages 2005
Biotin-phenyldiazomethane conjugates as labeling reagents at phosphate in mono and polynucleotides Fulltext Access 9 Pages 2005
Spirohydantoin derivatives of thiopyrano[2,3-b]pyridin-4(4H)-one as potent in vitro and in vivo aldose reductase inhibitors Fulltext Access 9 Pages 2005
Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates Fulltext Access 9 Pages 2005
Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats Fulltext Access 9 Pages 2005
Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: Role of mitogen-activated protein kinases and cell cycle regulators Fulltext Access 9 Pages 2005
Integration of steroid hormone initiated membrane action to genomic function in the brain Fulltext Access 9 Pages 2005
Tributyltin disturbs bovine adrenal steroidogenesis by two modes of action Fulltext Access 9 Pages 2005
Simulating redox coupled proton transfer in cytochrome c oxidase: Looking for the proton bottleneck Fulltext Access 9 Pages 2005
Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids Fulltext Access 9 Pages 2005
A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus-response experimental data Fulltext Access 9 Pages 2005
STAT4 is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells Fulltext Access 9 Pages 2005
Involvement of HP1α protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells Fulltext Access 9 Pages 2005
RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles Fulltext Access 9 Pages 2005