Mechanistic differences in inhibition of ubiquinol cytochrome c reductase by the proximal Qo-site inhibitors famoxadone and methoxyacrylate stilbene Fulltext Access 11 Pages 2005
Transglucosidic reactions of the Aspergillus niger Family 3 β-glucosidase: Qualitative and quantitative analyses and evidence that the transglucosidic rate is independent of pH Fulltext Access 11 Pages 2005
Cyclopropylamine inactivation of cytochromes P450: Role of metabolic intermediate complexes Fulltext Access 11 Pages 2005
S-Thiolation mimicry: Quantitative and kinetic analysis of redox status of protein cysteines by glutathione-affinity chromatography Fulltext Access 11 Pages 2005
Mechanistic studies of S-nitrosothiol formation by NO/O2 and by NO/methemoglobin Fulltext Access 11 Pages 2005
A retinoic acid binding cytochrome P450: CYP120A1 from Synechocystis sp. PCC 6803 Fulltext Access 11 Pages 2005
Small glutamine-rich tetratricopeptide repeat-containing protein is composed of three structural units with distinct functions Fulltext Access 11 Pages 2005
Heterologous expression and site-directed mutagenesis of an ascorbate-reducible cytochrome b561 Fulltext Access 11 Pages 2005
Stability of RNA isolated from human trabecular bone at post-mortem and surgery Fulltext Access 11 Pages 2005
Development of a new EPR spin trap, DOD-8C (N-[4-dodecyloxy-2-(7â²-carboxyhept-1â²-yloxy)benzylidene]-N-tert-butylamine N-oxide), for the trapping of lipid radicals at a predetermined depth within biological membranes Fulltext Access 11 Pages 2005
Prednisolone suppresses cyclosporin A-induced apoptosis but not cell cycle arrest in MDCK cells Fulltext Access 11 Pages 2005
Identification of Li+ binding sites and the effect of Li+ treatment on phospholipid composition in human neuroblastoma cells: a 7Li and 31P NMR study Fulltext Access 11 Pages 2005
Peroxynitrite-mediated oxidation of the C85S/C152E mutant of dihydrofolate reductase from Escherichia coli: functional and structural effects Fulltext Access 11 Pages 2005
Solid state 31P and 207Pb MAS NMR studies on polycrystalline O,Oâ²-dialkyldithiophosphate lead(II) complexes Fulltext Access 11 Pages 2005
Characterization of a putative fusogenic sequence in the E2 hepatitis G virus protein Fulltext Access 11 Pages 2005
Structural and mutational studies of organophosphorus hydrolase reveal a cryptic and functional allosteric-binding site Fulltext Access 11 Pages 2005
Energetics of carbohydrate binding to Momordica charantia (bitter gourd) lectin: An isothermal titration calorimetric study Fulltext Access 11 Pages 2005
The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria Fulltext Access 11 Pages 2005
Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-κB1 p105 Fulltext Access 11 Pages 2005
Divergent folding pathways of two homologous proteins, BPTI and tick anticoagulant peptide: Compartmentalization of folding intermediates and identification of kinetic traps Fulltext Access 11 Pages 2005
Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L. Fulltext Access 11 Pages 2005
Mechanism of action of ferrocene derivatives on the catalytic activity of topoisomerase IIα and β-Distinct mode of action of two derivatives Fulltext Access 11 Pages 2005
Human tartrate-resistant acid phosphatase becomes an effective ATPase upon proteolytic activation Fulltext Access 11 Pages 2005
Involvement of phospholipid, biomembrane integrity, and NO peroxidase activity in the NO catabolism by cytochrome c oxidase Fulltext Access 11 Pages 2005
Liposome composition effects on lipid mixing between cells expressing influenza virus hemagglutinin and bound liposomes Fulltext Access 11 Pages 2005
Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors Fulltext Access 11 Pages 2005
Effect of insulin and glucagon on accumulation of uroporphyrin and coproporphyrin from 5-aminolevulinate in hepatocyte cultures Fulltext Access 11 Pages 2005
Contribution of the copper ions in the dinuclear active site to the stability of Carcinus aestuarii hemocyanin Fulltext Access 11 Pages 2005
Differential roles of 3H-1,2-dithiole-3-thione-induced glutathione, glutathione S-transferase and aldose reductase in protecting against 4-hydroxy-2-nonenal toxicity in cultured cardiomyocytes Fulltext Access 11 Pages 2005
The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol Fulltext Access 11 Pages 2005
Photo-CIDNP experiments with an optimized presaturation pulse train, gated continuous illumination, and a background-nulling pulse grid Fulltext Access 11 Pages 2005
A study of the spin-echo spin-locking effect in multi-pulse sequences in 14N nuclear quadrupole resonance Fulltext Access 11 Pages 2005
Expression of manganese lipoxygenase in Pichia pastoris and site-directed mutagenesis of putative metal ligands Fulltext Access 11 Pages 2005
Temperature dependence of protein backbone motion from carbonyl 13C and amide 15N NMR relaxation Fulltext Access 11 Pages 2005
Structure determination of aligned systems by solid-state NMR magic angle spinning methods Fulltext Access 11 Pages 2005
3D NMR spectroscopy for resonance assignment and structure elucidation of proteins under MAS: novel pulse schemes and sensitivity considerations Fulltext Access 11 Pages 2005
Four complementary theoretical approaches for the analysis of NMR paramagnetic relaxation Fulltext Access 11 Pages 2005
Structure, function and interfacial allosterism in phospholipase A2: insight from the anion-assisted dimer Fulltext Access 11 Pages 2005
Increasing the sensitivity of 2D high-resolution NMR methods applied to quadrupolar nuclei Fulltext Access 11 Pages 2005
Mechanism of post-translational quinone formation in copper amine oxidases and its relationship to the catalytic turnover Fulltext Access 11 Pages 2005
Solution structure of BmP08, a novel short-chain scorpion toxin from Buthus martensi Karsch Fulltext Access 11 Pages 2005
Increasing 14N NQR signal by 1H-14N level crossing with small magnetic fields Fulltext Access 11 Pages 2005
Correction of concomitant gradient artifacts in experimental microtesla MRI Fulltext Access 11 Pages 2005
Heteronuclear decoupling interference during symmetry-based homonuclear recoupling in solid-state NMR Fulltext Access 11 Pages 2005
Distinct metal dependence for catalytic and structural functions in the l-arabinose isomerases from the mesophilic Bacillus halodurans and the thermophilic Geobacillus stearothermophilus Fulltext Access 11 Pages 2005
The use of multivariate MR imaging intensities versus metabolic data from MR spectroscopic imaging for brain tumour classification Fulltext Access 11 Pages 2005
Protein backbone dynamics from N-HN dipolar couplings in partially aligned systems: a comparison of motional models in the presence of structural noise Fulltext Access 11 Pages 2005
Abolition of oxygenase function, retention of NADPH oxidase activity, and emergence of peroxidase activity upon replacement of the axial cysteine-436 ligand by histidine in cytochrome P450 2B4 Fulltext Access 11 Pages 2005
Theoretical and experimental investigation of 13C relayed 2H-2H-COSY 2D experiments: Application to the analysis of weakly aligned solutes Fulltext Access 11 Pages 2005
Quantitative study of the effects of chemical shift tolerances and rates of SA cooling on structure calculation from automatically assigned NOE data Fulltext Access 11 Pages 2005
Species-specific mechanisms for cholesterol 7α-hydroxylase (CYP7A1) regulation by drugs and bile acids Fulltext Access 11 Pages 2005
Energetic differences between the specific binding of a 40Â bp DNA duplex and the lac promoter to lac repressor protein Fulltext Access 12 Pages 2005
Molecular insight into the effects of hypothyroidism on the developing cerebellum Fulltext Access 12 Pages 2005
Rotor-synchronized acquisition of quadrupolar satellite-transition NMR spectra: practical aspects and double-quantum filtration Fulltext Access 12 Pages 2005
Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues Fulltext Access 12 Pages 2005
The unexpected structural role of glutamate synthase [4Fe-4S]+1, +2 clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme β subunit Fulltext Access 12 Pages 2005
Expression, purification, and characterization of recombinant amorpha-4,11-diene synthase from Artemisia annua L. Fulltext Access 12 Pages 2005
Repression of 5-aminolevulinate synthase gene by the potent tumor promoter, TPA, involves multiple signal transduction pathways Fulltext Access 12 Pages 2005
Spatially encoded NMR and the acquisition of 2D magnetic resonance images within a single scan Fulltext Access 12 Pages 2005
A simulation algorithm based on Bloch equations and product operator matrix: application to dipolar and scalar couplings Fulltext Access 12 Pages 2005
An advanced EPR stopped-flow apparatus based on a dielectric ring resonator Fulltext Access 12 Pages 2005
Spin-edited 2D HSQC-TOCSY experiments for the measurement of homonuclear and heteronuclear coupling constants: Application to carbohydrates and peptides Fulltext Access 12 Pages 2005
Temperature dependence of the 1H chemical shift of tetramethylsilane in chloroform, methanol, and dimethylsulfoxide Fulltext Access 12 Pages 2005
A 13C field-cycling NMR relaxometry investigation of proton tunnelling in the hydrogen bond: Dynamic isotope effects, the influence of heteronuclear interactions and coupled relaxation Fulltext Access 12 Pages 2005
Determination of orientation distribution function of anisotropic paramagnetic species by analysis of ESR spectra angular dependence Fulltext Access 12 Pages 2005
Measuring 1H-1H and 1H-13C RDCs in methyl groups: example of pulse sequences with numerically optimized coherence transfer schemes Fulltext Access 12 Pages 2005
Multispin moments edited by multiple-quantum NMR: application to elastomers Fulltext Access 12 Pages 2005
Magnetic characterisation of rat muscle tissues after subcutaneous iron dextran injection Fulltext Access 12 Pages 2005
The kinase activity of human brain 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is regulated via inhibition by phosphoenolpyruvate Fulltext Access 12 Pages 2005
Erythropoietin hypersensitivity in primary familial and congenital polycythemia: Role of tyrosines Y285 and Y344 in erythropoietin receptor cytoplasmic domain Fulltext Access 12 Pages 2005
Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death Fulltext Access 12 Pages 2005
Probing the CYP3A4 active site by cysteine scanning mutagenesis and photoaffinity labeling Fulltext Access 12 Pages 2005
The PufX protein of Rhodobacter capsulatus affects the properties of bacteriochlorophyll a and carotenoid pigments of light-harvesting complex 1 Fulltext Access 12 Pages 2005
Protein phosphatase-1 inhibitor-3 is co-localized to the nucleoli and centrosomes with PP1γ1 and PP1α, respectively Fulltext Access 12 Pages 2005
Mitochondrial transporters involved in oleic acid utilization and glutamate metabolism in yeast Fulltext Access 12 Pages 2005
A novel Arnt-interacting protein Ainp2 enhances the aryl hydrocarbon receptor signaling Fulltext Access 12 Pages 2005
Cold stress-induced pea DNA helicase 47 is homologous to eIF4A and inhibited by DNA-interacting ligands Fulltext Access 12 Pages 2005
Mutational analysis of a monoterpene synthase reaction: Altered catalysis through directed mutagenesis of (â)-pinene synthase from Abies grandis Fulltext Access 12 Pages 2005