The pro-tumorigenic effects of metabolic alterations in glioblastoma including brain tumor initiating cells Fulltext Access 52 Pages 2018
Structure-activity relationship study of hypoxia-activated prodrugs for proteoglycan-targeted chemotherapy in chondrosarcoma Fulltext Access 53 Pages 2018
Improved measurements of scant hydrogen peroxide enable experiments that define its threshold of toxicity for Escherichia coli Fulltext Access 53 Pages 2018
Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting Fulltext Access 53 Pages 2018
In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction Fulltext Access 53 Pages 2018
Machine learning prioritizes synthesis of primaquine ureidoamides with high antimalarial activity and attenuated cytotoxicity Fulltext Access 53 Pages 2018
Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents Fulltext Access 54 Pages 2018
Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease Fulltext Access 54 Pages 2018
Anti-leishmanial click modifiable thiosemicarbazones: Design, synthesis, biological evaluation and in silico studies Fulltext Access 54 Pages 2018
Synthesis and antibacterial bioactivities of cationic deacetyl linezolid amphiphiles Fulltext Access 54 Pages 2018
Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness Fulltext Access 54 Pages 2018
Organic arsenicals target thioredoxin reductase followed by oxidative stress and mitochondrial dysfunction resulting in apoptosis Fulltext Access 55 Pages 2018
Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics Fulltext Access 56 Pages 2018
Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment Fulltext Access 57 Pages 2018
The role of nitrite in muscle function, susceptibility to contraction injury, and fatigability in sickle cell mice Fulltext Access 58 Pages 2018
Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis Fulltext Access 58 Pages 2018
Oligonucleotide aptamers against tyrosine kinase receptors: Prospect for anticancer applications Fulltext Access 59 Pages 2018
Synthesis and anticancer activity of novel water soluble benzimidazole carbamates Fulltext Access 59 Pages 2018
Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile Fulltext Access 59 Pages 2018
Drug discovery in tuberculosis. New drug targets and antimycobacterial agents Fulltext Access 59 Pages 2018
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system Fulltext Access 60 Pages 2018
Targeting mitochondrial dysfunction and oxidative stress in heart failure: Challenges and opportunities Fulltext Access 60 Pages 2018
Post-transcriptional regulation of the oxidative stress response in plants Fulltext Access 60 Pages 2018
Oxidant-specific biomarkers of oxidative stress. Association with atherosclerosis and implication for antioxidant effects Fulltext Access 61 Pages 2018
X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells Fulltext Access 61 Pages 2018
Significance of the mitochondrial thioredoxin reductase in cancer cells: An update on role, targets and inhibitors Fulltext Access 61 Pages 2018
Exploration of variations in proteome and metabolome for predictive diagnostics and personalized treatment algorithms: Innovative approach and examples for potential clinical application Fulltext Access 62 Pages 2018
Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes Fulltext Access 63 Pages 2018
Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment Fulltext Access 63 Pages 2018
Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors Fulltext Access 64 Pages 2018
Design, synthesis and biological evaluation of novel ring-opened cromakalim analogues with relaxant effects on vascular and respiratory smooth muscles and as stimulators of elastin synthesis Fulltext Access 65 Pages 2018
Pre-pregnancy maternal obesity associates with endoplasmic reticulum stress in human umbilical vein endothelium Fulltext Access 66 Pages 2018
Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition Fulltext Access 66 Pages 2018
Indole in the target-based design of anticancer agents: A versatile scaffold with diverse mechanisms Fulltext Access 66 Pages 2018
Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion Fulltext Access 67 Pages 2018
Dietary fibre for glycaemia control: Towards a mechanistic understanding Fulltext Access 68 Pages 2018
Recent developments of quinolone-based derivatives and their activities against Escherichia coli Fulltext Access 68 Pages 2018
Fluorine walk: The impact of fluorine in quinolone amides on their activity against African sleeping sickness Fulltext Access 68 Pages 2018
Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities Fulltext Access 68 Pages 2018
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors Fulltext Access 69 Pages 2018
Detailed account on activation mechanisms of ruthenium coordination complexes and their role as antineoplastic agents Fulltext Access 69 Pages 2018
Epidermal growth factor receptor: Structure-function informing the design of anticancer therapeutics Fulltext Access 71 Pages 2018
Success stories of natural product-based hybrid molecules for multi-factorial diseases Fulltext Access 74 Pages 2018
Type 2 diabetes - An autoinflammatory disease driven by metabolic stress Fulltext Access 75 Pages 2018
Structure-based design of bacterial transglycosylase inhibitors incorporating biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties Fulltext Access 77 Pages 2018
Synthesis and biological evaluation of dihydroquinoline carboxamide derivatives as anti-tubercular agents Fulltext Access 78 Pages 2018
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease Fulltext Access 81 Pages 2018
Discovery of a potent glucokinase activator with a favorable liver and pancreas distribution pattern for the treatment of type 2 diabetes mellitus Fulltext Access 82 Pages 2018
Therapeutic journery of nitrogen mustard as alkylating anticancer agents: Historic to future perspectives Fulltext Access 94 Pages 2018
Syntheses and anti-pancreatic cancer activities of rakicidin A analogues Fulltext Access 101 Pages 2018
An overview of quinazolines: Pharmacological significance and recent developments Fulltext Access 103 Pages 2018
Pyrrole: An insight into recent pharmacological advances with structure activity relationship Fulltext Access 110 Pages 2018
Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition Fulltext Access 112 Pages 2018
Bioinformatics analysis of gene expression profiles to diagnose crucial and novel genes in glioblastoma multiform Fulltext Access 123 Pages 2018
Recent advancement of piperidine moiety in treatment of cancer- A review Fulltext Access 133 Pages 2018
Case reportDedifferentiated chondrosarcoma with “adamantinoma-like” features: A case report and review of literature Fulltext Access 4 Pages 2017
Original articlePlacental findings in feto-maternal hemorrhage in livebirth and stillbirth Fulltext Access 4 Pages 2017
Original articleMalignant tumors associated with ovarian mature teratoma: A single institution experience Fulltext Access 4 Pages 2017
Prevalence of adeno-associated virus and human papillomavirus DNA in Iranian women with and without cervical cancer Fulltext Access 4 Pages 2017
Case reportAdenosquamous gallbladder carcinoma: Multigene hotspot mutational profiling reveals a monoclonal origin of the two components Fulltext Access 4 Pages 2017
Case reportSirenomelia associated with discoid adrenal and lumbar meningocoele: An autopsy report Fulltext Access 4 Pages 2017
Case reportGranulomas within renal epithelial neoplasms in patients with sarcoidosis: A causal association? Fulltext Access 4 Pages 2017
Original ArticleUpregulation of uc.189 in patients with esophageal squamous cell carcinoma and its clinicopathologic value Fulltext Access 4 Pages 2017
Review articleSkin regeneration in three dimensions, current status, challenges and opportunities Fulltext Access 4 Pages 2017
Can cannibalizing cancer cells challenge classic cell death classification? Fulltext Access 4 Pages 2017
A exceptional collision tumor of primary adrenal angiosarcoma and non-functioning adrenocortical adenoma Fulltext Access 4 Pages 2017
Case reportMetastatic intestinal adenocarcinoma to a lymph node involved by follicular lymphoma: The importance of looking beyond the apparent Fulltext Access 4 Pages 2017
Human DiseasesQuality assurance of anatomic pathology diagnoses: Comparison of alternate approaches Fulltext Access 4 Pages 2017
Case reportPrimary pulmonary/pleural melanoma in a 13 year-old presenting as pleural effusion Fulltext Access 4 Pages 2017
Quantitation of bleeding symptoms in a national registry of patients with inherited platelet disorders Fulltext Access 4 Pages 2017
Imaging the human placental microcirculation with micro-focus computed tomography: Optimisation of tissue preparation and image acquisition Fulltext Access 4 Pages 2017
Morphology based scoring of chromosomal instability and its correlation with cell viability Fulltext Access 4 Pages 2017
Nuclear maspin expression: A biomarker for budding assessment in colorectal cancer specimens Fulltext Access 4 Pages 2017
Concomitant Epstein-Barr Virus-associated smooth muscle tumor and granulomatous inflammation of the liver Fulltext Access 4 Pages 2017
Short communicationAnomalies in the dominant sarcoidosis paradigm justify its displacement Fulltext Access 4 Pages 2017
Relative amount of telomeric sequences in terminal villi does not differ between normal term placentas and placentas from patients with well-controlled type 1 diabetes mellitus Fulltext Access 4 Pages 2017
Placental pathology and clinical trials: Histopathology data from prior and study pregnancies may improve analysis Fulltext Access 4 Pages 2017