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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Design, synthesis, and biological evaluation of optimized phthalazine derivatives as hedgehog signaling pathway inhibitors
Fulltext Access 42 Pages 2017
Endoplasmic reticulum-mitochondria calcium signaling in hepatic metabolic diseases
Fulltext Access 42 Pages 2017
An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors
Fulltext Access 42 Pages 2017
Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma
Fulltext Access 42 Pages 2017
Synthesis and biological evaluation of salinomycin triazole analogues as anticancer agents
Fulltext Access 42 Pages 2017
Recent developments in small molecule therapies for renal cell carcinoma
Fulltext Access 42 Pages 2017
Identifying potential markers in Breast Cancer subtypes using plasma label-free proteomics
Fulltext Access 42 Pages 2017
Arachidonic acid sex-dependently affects obesity through linking gut microbiota-driven inflammation to hypothalamus-adipose-liver axis
Fulltext Access 42 Pages 2017
Microbial recognition and danger signals in sepsis and trauma
Fulltext Access 42 Pages 2017
An integrated proteomic and transcriptomic analysis of perivitelline fluid proteins in a freshwater gastropod laying aerial eggs
Fulltext Access 42 Pages 2017
A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma
Fulltext Access 42 Pages 2017
Multiplexed mass spectrometry monitoring of biomarker candidates for osteoarthritis
Fulltext Access 42 Pages 2017
Pseudomonas aeruginosa develops Ciprofloxacin resistance from low to high level with distinctive proteome changes
Fulltext Access 42 Pages 2017
Modes of antibacterial action of curcumin under dark and light conditions: A toxicoproteomics approach
Fulltext Access 42 Pages 2017
Molecular mechanisms of trauma-induced acute kidney injury: Inflammatory and metabolic insights from animal models
Fulltext Access 43 Pages 2017
Formoterol and fluticasone propionate combination improves histone deacetylation and anti-inflammatory activities in bronchial epithelial cells exposed to cigarette smoke
Fulltext Access 43 Pages 2017
A comparison of cangrelor, prasugrel, ticagrelor, and clopidogrel in patients undergoing percutaneous coronary intervention: A network meta-analysis
Fulltext Access 43 Pages 2017
Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys
Fulltext Access 43 Pages 2017
The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production
Fulltext Access 44 Pages 2017
Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors
Fulltext Access 44 Pages 2017
Chemical basis for the disparate neuroprotective effects of the anthocyanins, callistephin and kuromanin, against nitrosative stress
Fulltext Access 44 Pages 2017
Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease
Fulltext Access 44 Pages 2017
Interactions of long-chain homologues of colchicine with tubulin
Fulltext Access 44 Pages 2017
Prodrugs of triterpenoids and their derivatives
Fulltext Access 45 Pages 2017
Exploration of flexible phenylpropylurea scaffold as novel cardiac myosin activators for the treatment of systolic heart failure
Fulltext Access 45 Pages 2017
Do You Believe It? Verbal Suggestions Influence the Clinical and Neural Effects of Escitalopram in Social Anxiety Disorder: A Randomized Trial
Fulltext Access 45 Pages 2017
Reprogramming of central carbon metabolism in cancer stem cells
Fulltext Access 45 Pages 2017
Chronic Exposure to Subtherapeutic Antibiotics Aggravates Ischemic Stroke Outcome in Mice
Fulltext Access 45 Pages 2017
Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats
Fulltext Access 45 Pages 2017
Isoniazid derivatives and their anti-tubercular activity
Fulltext Access 45 Pages 2017
A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome
Fulltext Access 45 Pages 2017
Integrating cell biology and proteomic approaches in plants
Fulltext Access 45 Pages 2017
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase
Fulltext Access 45 Pages 2017
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease
Fulltext Access 45 Pages 2017
Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold
Fulltext Access 45 Pages 2017
Graphene- gold based nanocomposites applications in cancer diseases; Efficient detection and therapeutic tools
Fulltext Access 45 Pages 2017
Myeloid leukemia factor-1 is a novel modulator of neonatal rat cardiomyocyte proliferation
Fulltext Access 46 Pages 2017
Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death
Fulltext Access 46 Pages 2017
Diabetes-induced hepatic oxidative stress: a new pathogenic role for glycated albumin
Fulltext Access 46 Pages 2017
Free radical production and antioxidant status in brain cortex non-synaptic mitochondria and synaptosomes at alcohol hangover onset
Fulltext Access 46 Pages 2017
Proteasome inhibitors in cancer therapy: Treatment regimen and peripheral neuropathy as a side effect
Fulltext Access 46 Pages 2017
Violet Light Exposure Can Be a Preventive Strategy Against Myopia Progression
Fulltext Access 46 Pages 2017
Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases
Fulltext Access 46 Pages 2017
Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management
Fulltext Access 46 Pages 2017
Natural and synthetic bioactive inhibitors of glycogen synthase kinase
Fulltext Access 46 Pages 2017
Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators
Fulltext Access 46 Pages 2017
Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania
Fulltext Access 46 Pages 2017
Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives
Fulltext Access 46 Pages 2017
Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics
Fulltext Access 46 Pages 2017
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects
Fulltext Access 46 Pages 2017
A mass spectrometry-based proteomic analysis of Homer2-interacting proteins in the mouse brain
Fulltext Access 47 Pages 2017
New intracellular activities of matrix metalloproteinases shine in the moonlight
Fulltext Access 47 Pages 2017
Novel flavonolignan hybrid antioxidants: From enzymatic preparation to molecular rationalization
Fulltext Access 47 Pages 2017
Extracellular superoxide dismutase and its role in cancer
Fulltext Access 47 Pages 2017
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells
Fulltext Access 47 Pages 2017
Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways
Fulltext Access 47 Pages 2017
Melanocortin neurons: Multiple routes to regulation of metabolism
Fulltext Access 47 Pages 2017
Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy
Fulltext Access 47 Pages 2017
Inhibition of mitochondrial fission prevents hypoxia-induced metabolic shift and cellular proliferation of pulmonary arterial smooth muscle cells
Fulltext Access 47 Pages 2017
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea
Fulltext Access 47 Pages 2017
Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures
Fulltext Access 47 Pages 2017
In-depth comparative analysis of the chicken eggshell membrane proteome
Fulltext Access 47 Pages 2017
Design, selective alkylation and X-ray crystal structure determination of dihydro-indolyl-1,2,4-triazole-3-thione and its 3-benzylsulfanyl analogue as potent anticancer agents
Fulltext Access 47 Pages 2017
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model
Fulltext Access 48 Pages 2017
Synthesis and biological evaluation of new substituted thioglycolurils, their analogues and derivatives
Fulltext Access 48 Pages 2017
Comparison of the redox chemistry of sulfur- and selenium-containing analogs of uracil
Fulltext Access 48 Pages 2017
Prodrug strategy for cancer cell-specific targeting: A recent overview
Fulltext Access 48 Pages 2017
Neutrophil derived microparticles increase mortality and the counter-inflammatory response in a murine model of sepsis
Fulltext Access 49 Pages 2017
New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation
Fulltext Access 49 Pages 2017
Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity
Fulltext Access 49 Pages 2017
Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy
Fulltext Access 49 Pages 2017
Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells
Fulltext Access 49 Pages 2017
The nitroxyl donor Angeli's salt ameliorates Staphylococcus aureus-induced septic arthritis in mice
Fulltext Access 49 Pages 2017
Discovery of novel polycyclic spiro-fused carbocyclicoxindole-based anticancer agents
Fulltext Access 49 Pages 2017
Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Fulltext Access 50 Pages 2017
Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids
Fulltext Access 50 Pages 2017
Maternal alterations in the proteome of the medial prefrontal cortex in rat
Fulltext Access 50 Pages 2017
Tribenzyltin carboxylates as anticancer drug candidates: Effect on the cytotoxicity, motility and invasiveness of breast cancer cell lines
Fulltext Access 50 Pages 2017
Novel insights into the antioxidant role of tauroursodeoxycholic acid in experimental models of Parkinson's disease
Fulltext Access 50 Pages 2017
Synaptic proteome changes in the hypothalamus of mother rats
Fulltext Access 50 Pages 2017
Synthesis of novel benzylidene analogues of betulinic acid as potent cytotoxic agents
Fulltext Access 50 Pages 2017
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease
Fulltext Access 50 Pages 2017
Recent advances in polysaccharides for osteoarthritis therapy
Fulltext Access 50 Pages 2017
Structures and biochemical evaluation of silver(I) 5,5-diethylbarbiturate complexes with bis(diphenylphosphino)alkanes as potential antimicrobial and anticancer agents
Fulltext Access 51 Pages 2017
Transdifferentiation and reprogramming: Overview of the processes, their similarities and differences
Fulltext Access 51 Pages 2017
Discovery of novel 3-(hydroxyalkoxy)-2-alkylchromen-4-one analogs as interleukin-5 inhibitors
Fulltext Access 51 Pages 2017
Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands
Fulltext Access 52 Pages 2017
A glimpse into the modulation of post-translational modifications of human-colonizing bacteria
Fulltext Access 52 Pages 2017
Cytoskeleton and nuclear lamina affection in recessive osteogenesis imperfecta: A functional proteomics perspective
Fulltext Access 52 Pages 2017
Design and synthesis of indoline thiohydantoin derivatives based on enzalutamide as antiproliferative agents against prostate cancer
Fulltext Access 52 Pages 2017
Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus
Fulltext Access 52 Pages 2017
Induction of hypothyroidism during early postnatal stages triggers a decrease in cognitive performance by decreasing hippocampal synaptic plasticity
Fulltext Access 52 Pages 2017
Epigenetic dysfunctional diseases and therapy for infection and inflammation
Fulltext Access 52 Pages 2017
Proteomic and physiological approach reveals drought-induced changes in rapeseeds: Water-saver and water-spender strategy
Fulltext Access 53 Pages 2017
Design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs
Fulltext Access 53 Pages 2017
Proteolytic control of Interleukin-11 and Interleukin-6 biology
Fulltext Access 53 Pages 2017
Synthesis of 1,2,3-triazole hydrazide derivatives exhibiting anti-phytopathogenic activity
Fulltext Access 54 Pages 2017
Lysine acetylation and cancer: A proteomics perspective
Fulltext Access 54 Pages 2017
Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms
Fulltext Access 54 Pages 2017
Rational design, synthesis and biological screening of triazine-triazolopyrimidine hybrids as multitarget anti-Alzheimer agents
Fulltext Access 54 Pages 2017
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