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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Aberrant methylation of DAPK in long-standing ulcerative colitis and ulcerative colitis-associated carcinoma
Fulltext Access 9 Pages 2010
In vitro immunomodulatory activity of Lactobacillus fermentum CECT5716 and Lactobacillus salivarius CECT5713: two probiotic strains isolated from human breast milk
Fulltext Access 9 Pages 2010
C1q induces a rapid up-regulation of P-selectin and modulates collagen- and collagen-related peptide-triggered activation in human platelets
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Thymic microenvironmental alterations in experimentally induced diabetes
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Uncoupling between CD1d upregulation induced by retinoic acid and conduritol-B-epoxide and iNKT cell responsiveness
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Transcriptional effects of Colony-stimulating factor-1 in mouse macrophages
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Protective effects of interleukin-6 in lipopolysaccharide (LPS)-induced experimental endotoxemia are linked to alteration in hepatic anti-oxidant enzymes and endogenous cytokines
Fulltext Access 9 Pages 2010
Distribution of macrophages and T cells in syngrafts and allografts after experimental rat lung transplantation
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Macrophage activation by gastric fluid suggests MMP involvement in aspiration-induced lung disease
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Lack of galectin-3 alleviates trypanosomiasis-associated anemia of inflammation
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The novel RUNX3/p33 isoform is induced upon monocyte-derived dendritic cell maturation and downregulates IL-8 expression
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Native polymeric forms of properdin selectively bind to targets and promote activation of the alternative pathway of complement
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A case of epithelial–myoepithelial carcinoma of the bronchus – A review of reported cases and a comparison with other salivary gland-type carcinomas of the bronchus
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Detection of protein on BTLAlow cells and in vivo antibody-mediated down-modulation of BTLA on lymphoid and myeloid cells of C57BL/6 and BALB/c BTLA allelic variants
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N-Acetyl-L-Methionyl-L-Dopa-Methyl Ester as a dual acting drug that relieves L-Dopa-induced oxidative toxicity
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NOX activity in brain aging: Exacerbation by high fat diet
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Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative stress and suppression of the antioxidant protective system
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Uncoupling protein-2 knockdown mediates the cytotoxic effects of cisplatin
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Histidine, cystine, glutamine, and threonine collectively protect astrocytes from the toxicity of zinc
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Epigallocatechin-3-gallate inhibits mast cell degranulation, leukotriene C4 secretion, and calcium influx via mitochondrial calcium dysfunction
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Reactive oxygen species as mediators of membrane-dependent signaling induced by ultrafine particles
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Mechanism of hemoglobin-induced cellular injury in desiccated red blood cells
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Sustained release nitric oxide from long-lived circulating nanoparticles
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Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes
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Involvement of thioredoxin domain-containing 5 in resistance to nitrosative stress
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Antitumour and immune-adjuvant activities of protein-tyrosine kinase inhibitors
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L-type calcium channels and cytochrome b5 reductase are components of protein complexes tightly associated with lipid rafts microdomains of the neuronal plasma membrane
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Proteasome and oxidative phoshorylation changes may explain why aging is a risk factor for neurodegenerative disorders
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Caenorhabditis elegans, a pluricellular model organism to screen new genes involved in mitochondrial genome maintenance
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Developing c-MET pathway inhibitors for cancer therapy: progress and challenges
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APOE and cholesterol homeostasis in Alzheimer's disease
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p53 post-translational modification: deregulated in tumorigenesis
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Lessons for cardiac regeneration and repair through development
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The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease
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Circulating tumour cells in cancer patients: challenges and perspectives
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Small-molecule delivery by nanoparticles for anticancer therapy
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Therapeutic prospects for mitochondrial disease
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Anticancer genes: inducers of tumour-specific cell death signalling
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Oxidative stress defense in human-skin-derived mesenchymal stem cells versus human keratinocytes: Different mechanisms of protection and cell selection
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Inflammatory networks during cellular senescence: causes and consequences
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Vascular responses to the multiple overlapped paclitaxel-eluting stents for the treatment of bare-metal in-stent restenotic lesions: angiographic and intravascular ultrasound analysis from the TAXUS-V ISR Trial
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RETRACTED: An innovative noninvasive respiratory stress test indicates significant coronary artery disease
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Hematologically important mutations: The autosomal recessive forms of chronic granulomatous disease (second update)
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Anion conductance of the human red cell is carried by a maxi-anion channel
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Notch protection against apoptosis in T-ALL cells mediated by GIMAP5
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cJun modulates Gγ-globin gene expression via an upstream cAMP response element
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Hematopoietic cells from Ube1L-deficient mice exhibit an impaired proliferation defect under the stress of bone marrow transplantation
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Cellular mechanisms of estradiol-mediated sexual differentiation of the brain
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Different mechanisms regulate CD4+ T cell independent induction of oral and nasal tolerance of CD8+ T cells
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UV irradiation after immunization induces type 1 regulatory T cells that suppress Th2-type immune responses via secretion of IL-10
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Investigating the structural basis of arylamides to improve potency against M. tuberculosis strain through molecular dynamics simulations
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Some insights into mechanism for binding and drug resistance of wild type and I50V V82A and I84V mutations in HIV-1 protease with GRL-98065 inhibitor from molecular dynamic simulations
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Synthesis, single-crystal characterization and preliminary biological evaluation of novel ferrocenyl pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives
Fulltext Access 9 Pages 2010
Substituted 2-Aminothiopen-derivatives: A potential new class of GluR6-Antagonists
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Synthesis and antioxidant properties of some novel 5H-dibenz[b,f]azepine derivatives in different in vitro model systems
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Synthesis and structure–activity relationship of 3-O-acylated (–)-epigallocatechins as 5α-reductase inhibitors
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Structure–cytotoxicity relationship in a series of N-phosphorus substituted E,E-3,5-bis(3-pyridinylmethylene)- and E,E-3,5-bis(4-pyridinylmethylene)piperid-4-ones
Fulltext Access 9 Pages 2010
Design, synthesis and inhibitory activity against Mycobacterium tuberculosis thymidine monophosphate kinase of acyclic nucleoside analogues with a distal imidazoquinolinone
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Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands
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On the isomerisation of cefozopran in solution
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Mitogen-activated protein kinase 4 of Leishmania parasite as a therapeutic target
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A regio- and stereoselective 1,3-dipolar cycloaddition for the synthesis of novel spiro-pyrrolothiazolyloxindoles and their antitubercular evaluation
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Molecular docking and QSAR study on steroidal compounds as aromatase inhibitors
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Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking
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New class of potent antitumor acylhydrazone derivatives containing furan
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Synthesis of (S)-(+)-decursin and its analogues as potent inhibitors of melanin formation in B16 murine melanoma cells
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Different expression of Fibrinopeptide A and related fragments in serum of type 1 diabetic patients with nephropathy
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A computational platform for MALDI-TOF mass spectrometry data: Application to serum and plasma samples
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Proteomics meets blood banking: Identification of protein targets for the improvement of platelet quality
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Proteomic analysis reveals late exercise effects on cardiac remodeling following myocardial infarction
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Proteomics and ovarian cancer: Integrating proteomics information into clinical care
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The influence of the acyl chain composition of cardiolipin on the stability of mitochondrial complexes; An unexpected effect of cardiolipin in α-ketoglutarate dehydrogenase and prohibitin complexes
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Combining low- and high-energy tandem mass spectra for optimized peptide quantification with isobaric tags
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Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry
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A rapid screening method for cell lines producing singly-tagged recombinant proteins using the “TARGET tag” system
Fulltext Access 9 Pages 2010
Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents
Fulltext Access 9 Pages 2010
Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2
Fulltext Access 9 Pages 2010
Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction
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Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ
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Attenuated cardiovascular hypertrophy and oxidant generation in response to angiotensin II infusion in glutaredoxin-1 knockout mice
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Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet
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Oxidation enhances myofibrillar protein degradation via calpain and caspase-3
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QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations
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Novel cyclic-imide peptidomimetics as aminopeptidase N inhibitors. Structure-based design, chemistry and activity evaluation. II
Fulltext Access 9 Pages 2010
Synthesis and cytotoxic evaluation of N2-benzylated quaternary β-carboline amino acid ester conjugates
Fulltext Access 9 Pages 2010
Synthesis, biological and medicinal significance of S-glycosido-thieno[2,3-d]-pyrimidines as new anti-inflammatory and analgesic agents
Fulltext Access 9 Pages 2010
A novel copper complex of salicylaldehyde pyrazole hydrazone induces apoptosis through up-regulating integrin β4 in H322 lung carcinoma cells
Fulltext Access 9 Pages 2010
Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors
Fulltext Access 9 Pages 2010
Heard it through the grapevine: Proteomic perspective on grape and wine
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New dimeric cyclodiphosph(V)azane complexes of Cr(III), Co(II), Ni(II), Cu(II), and Zn(II): Preparation, characterization and biological activity studies
Fulltext Access 9 Pages 2010
Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity
Fulltext Access 9 Pages 2010
Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective
Fulltext Access 9 Pages 2010
Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities – Part-1
Fulltext Access 9 Pages 2010
Synthesis of 2-substituted-N-[4-(1-methyl-4,5-diphenyl-1H-imidazole-2-yl)phenyl]acetamide derivatives and evaluation of their anticancer activity
Fulltext Access 9 Pages 2010
Novel 6,8-dibromo-4(3H)quinazolinone derivatives of anti-bacterial and anti-fungal activities
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Synthesis and biological evaluation of novel spiro 6-methoxytetralin-1,3′-pyrrolidine based organoselenocyanates against cadmium-induced oxidative and hepatic damage in mice
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Graphical contents list
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Synthesis and antitumor evaluation of analogues of the marine pyrroloiminoquinone tsitsikammamines
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Designing dendrimers for ocular drug delivery
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Design, synthesis and docking studies of new furobenzopyranones and pyranobenzopyranones as photoreagent towards DNA and as antimicrobial agents
Fulltext Access 9 Pages 2010
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