Analgesic, anti-pyretic and DNA cleavage studies of novel pyrimidine derivatives of coumarin moiety Fulltext Access 9 Pages 2010
Drosophila Syntrophins are involved in locomotion and regulation of synaptic morphology Fulltext Access 9 Pages 2010
Interleukin-4 up-regulates 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in human lung cancer cells Fulltext Access 9 Pages 2010
6-Substituted 2-(N-trifluoroacetylamino)imidazopyridines induce cell cycle arrest and apoptosis in SK-LU-1 human cancer cell line Fulltext Access 9 Pages 2010
Design, synthesis, and biological evaluation of novel pyrimidine derivatives as CDK2 inhibitors Fulltext Access 9 Pages 2010
Predictive comparative QSAR modelling of (phenylpiperazinyl-alkyl) oxindoles as selective 5-HT1A antagonists by stepwise regression, PCRA, FA-MLR and PLS techniques Fulltext Access 9 Pages 2010
Pharmacophoric model building for antitubercular activity of the individual Schiff bases of small combinatorial library Fulltext Access 9 Pages 2010
Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid Fulltext Access 9 Pages 2010
New pyrazoles incorporating pyrazolylpyrazole moiety: Synthesis, anti-HCV and antitumor activity Fulltext Access 9 Pages 2010
Synthesis, characterization and structure–activity relationship of novel N-phosphorylated E,E-3,5-bis(thienylidene)piperid-4-ones Fulltext Access 9 Pages 2010
Molecular modeling study of binding site selectivity of TQMP to G-quadruplex DNA Fulltext Access 9 Pages 2010
Synthesis, X-ray structures and cytotoxic activity of platinum(II), palladium(II) and copper(II) complexes with chelating ligands Fulltext Access 9 Pages 2010
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis Fulltext Access 9 Pages 2010
Cytotoxic N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides: Structure–activity relationships and synergistic studies Fulltext Access 9 Pages 2010
Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter Fulltext Access 9 Pages 2010
‘On water’ assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents Fulltext Access 9 Pages 2010
Carbonic anhydrase inhibitors: Synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides Fulltext Access 9 Pages 2010
A new insulin-enhancing agent: [N,N′-bis(4-hydroxysalicylidene)-o-phenylene-diamine]oxovanadium(IV) and its permeability and cytotoxicity Fulltext Access 9 Pages 2010
Design, synthesis and determination of antifungal activity of 5(6)-substituted benzotriazoles Fulltext Access 9 Pages 2010
Prediction of air to liver partition coefficient for volatile organic compounds using QSAR approaches Fulltext Access 9 Pages 2010
Synthesis and potential cytotoxic activity of new phenanthrylphenol-pyrrolobenzodiazepines Fulltext Access 9 Pages 2010
3D QSAR pharmacophore based virtual screening and molecular docking for identification of potential HSP90 inhibitors Fulltext Access 9 Pages 2010
Synthesis of novel sulfanilamide-derived 1,2,3-triazoles and their evaluation for antibacterial and antifungal activities Fulltext Access 9 Pages 2010
RIP2: A novel player in the regulation of keratinocyte proliferation and cutaneous wound repair? Fulltext Access 9 Pages 2010
The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy Fulltext Access 9 Pages 2010
Omega-3 fatty acids in cancer, the protectors of good and the killers of evil? Fulltext Access 9 Pages 2010
Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase Fulltext Access 9 Pages 2010
TGFβ2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion Fulltext Access 9 Pages 2010
NFAT5 regulates transcription of the mouse telomerase reverse transcriptase gene Fulltext Access 9 Pages 2010
AP-2α suppresses skeletal myoblast proliferation and represses fibroblast growth factor receptor 1 promoter activity Fulltext Access 9 Pages 2010
DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells Fulltext Access 9 Pages 2010
RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells Fulltext Access 9 Pages 2010
Accumulation of piRNAs in the chromatoid bodies purified by a novel isolation protocol Fulltext Access 9 Pages 2010
S-phase and DNA damage activated establishment of Sister chromatid cohesion—importance for DNA repair Fulltext Access 9 Pages 2010
Osteoclast migration on phosphorylated osteopontin is regulated by endogenous tartrate-resistant acid phosphatase Fulltext Access 9 Pages 2010
Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding Fulltext Access 9 Pages 2010
Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: Comparison with other compounds of the same kind and relationship with logP values Fulltext Access 9 Pages 2010
Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells Fulltext Access 9 Pages 2010
Halofuginone inhibits Smad3 phosphorylation via the PI3K/Akt and MAPK/ERK pathways in muscle cells: Effect on myotube fusion Fulltext Access 9 Pages 2010
Roles of lysophosphatidic acid and the Rho-associated kinase pathway in the migration of dental pulp cells Fulltext Access 9 Pages 2010
Bortezomib induces autophagic death in proliferating human endothelial cells Fulltext Access 9 Pages 2010
Ornithine decarboxylase and extracellular polyamines regulate microvascular sprouting and actin cytoskeleton dynamics in endothelial cells Fulltext Access 9 Pages 2010
Novel markers of mesenchymal stem cells defined by genome-wide gene expression analysis of stromal cells from different sources Fulltext Access 9 Pages 2010
Bmi-1 extends the life span of normal human oral keratinocytes by inhibiting the TGF-β signaling Fulltext Access 9 Pages 2010
Genetic recombination pathways and their application for genome modification of human embryonic stem cells Fulltext Access 9 Pages 2010
Expression of paired-like homeodomain transcription factor 2c (PITX2c) in epidermal keratinocytes Fulltext Access 9 Pages 2010
Double stranded RNA-dependent protein kinase is involved in osteoclast differentiation of RAW264.7 cells in vitro Fulltext Access 9 Pages 2010
Exploring benzcyclo derivatives as potent aromatase inhibitors using ligand-based modeling studies Fulltext Access 9 Pages 2010
Poly propyl ether imine (PETIM) dendrimer: A novel non-toxic dendrimer for sustained drug delivery Fulltext Access 9 Pages 2010
Synthesis and evaluation of novel stearoyl-CoA desaturase 1 inhibitors: 1′-{6-[5-(pyridin-3-ylmethyl)-1,3,4-oxadiazol-2-yl]pyridazin-3-yl}-3,4-dihydrospiro[chromene-2,4′-piperidine] analogs Fulltext Access 9 Pages 2010
3D-QSAR pharmacophore modeling and in silico screening of new Bcl-xl inhibitors Fulltext Access 9 Pages 2010
Synthesis and in vitro cytostatic activity of new β-d-arabino furan[1′,2′:4,5]oxazolo- and arabino-pyrimidinone derivatives Fulltext Access 9 Pages 2010
Synthesis and cytotoxic evaluation of β-alkyl or β-aryl-δ-methyl-α-methylene-δ-lactones. Comparison with the corresponding γ-lactones Fulltext Access 9 Pages 2010
Synthesis and antitumor evaluation of novel diarylsulfonylurea derivatives: Molecular modeling applications Fulltext Access 9 Pages 2010
Synthesis, antitumor activity and molecular docking study of novel Sulfonamide-Schiff's bases, thiazolidinones, benzothiazinones and their C-nucleoside derivatives Fulltext Access 9 Pages 2010
Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives Fulltext Access 9 Pages 2010
Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents Fulltext Access 9 Pages 2010
Synthesis and biological evaluation of N-aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents Fulltext Access 9 Pages 2010
Synthesis, anti-HCV, antioxidant, and peroxynitrite inhibitory activity of fused benzosuberone derivatives Fulltext Access 9 Pages 2010
Synthesis and antimalarial evaluation of 1, 3, 5-trisubstituted pyrazolines Fulltext Access 9 Pages 2010
Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines Fulltext Access 9 Pages 2010
Synthesis and biological evaluation of cyclic nitrogen mustards based on carnitine framework Fulltext Access 9 Pages 2010
Synthesis and biological evaluation of novel 2,4′-bis substituted diphenylamines as anticancer agents and potential epidermal growth factor receptor tyrosine kinase inhibitors Fulltext Access 9 Pages 2010
Design, synthesis and anti-ulcerogenic effect of some of furo-salicylic acid derivatives on acetic acid-induced ulcerative colitis Fulltext Access 9 Pages 2010
Influence of bulky 3,3′-diphenylalanine enantiomers replacing position 2 of AVP analogues on their conformations: NMR and molecular modeling studies Fulltext Access 9 Pages 2010
Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents Fulltext Access 9 Pages 2010
Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: Pharmacophore modeling and molecular docking studies Fulltext Access 9 Pages 2010
Synthesis and evaluation of graveoline and graveolinine derivatives with potent anti-angiogenesis activities Fulltext Access 9 Pages 2010
Design, synthesis, and antitubercular evaluation of novel series of 3-benzofuran-5-aryl-1-pyrazolyl-pyridylmethanone and 3-benzofuran-5-aryl-1-pyrazolylcarbonyl-4-oxo-naphthyridin analogs Fulltext Access 9 Pages 2010
Cytotoxicity against cholangiocarcinoma cell lines of zerumbone derivatives Fulltext Access 9 Pages 2010
Synthesis and antibacterial activity of 3-O-carbamoyl derivatives of 6,11-di-O-methylerythromycin A: A novel class of acylides Fulltext Access 9 Pages 2010
Synthesis and antibacterial activities of 6-O-methylerythromycin A 9-O-(3-aryl-2-propenyl) oxime ketolide, 2,3-enol ether, and alkylide analogues Fulltext Access 9 Pages 2010
Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building Fulltext Access 9 Pages 2010
Anti-tubercular agents. Part 5: Synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners Fulltext Access 9 Pages 2010
Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase Fulltext Access 9 Pages 2010
Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives Fulltext Access 9 Pages 2010
Ligand and structure based pharmacophore modeling to facilitate novel histone deacetylase 8 inhibitor design Fulltext Access 9 Pages 2010
Mn(II), Co(II) and Zn(II) complexes with heterocyclic substituted thiosemicarbazones: Synthesis, characterization, X-ray crystal structures and antitumor comparison Fulltext Access 9 Pages 2010
5D-QSAR for spirocyclic σ1 receptor ligands by Quasar receptor surface modeling Fulltext Access 9 Pages 2010
Synthesis of ruthenium(II) complexes and characterization of their cytotoxicity in vitro, apoptosis, DNA-binding and antioxidant activity Fulltext Access 9 Pages 2010
Synthesis and dual PPARα/δ agonist effects of 1,4-disubstituted 1,2,3-triazole analogues of GW 501516 Fulltext Access 9 Pages 2010
Structural determinants of resveratrol for cell proliferation inhibition potency: Experimental and docking studies of new analogs Fulltext Access 9 Pages 2010
Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold Fulltext Access 9 Pages 2010
Chiral preference of l-tryptophan derived metal-based antitumor agent of late 3d-metal ions (Co(II), Cu(II) and Zn(II)) in comparison to d- and dl-tryptophan analogues: Their in vitro reactivity towards CT DNA, 5′-GMP and 5′-TMP Fulltext Access 9 Pages 2010
Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists Fulltext Access 9 Pages 2010
Molecular modeling studies of Rho kinase inhibitors using molecular docking and 3D-QSAR analysis Fulltext Access 9 Pages 2010
Metal based biologically active compounds: Design, synthesis, and antibacterial/antifungal/cytotoxic properties of triazole-derived Schiff bases and their oxovanadium(IV) complexes Fulltext Access 9 Pages 2010
Synthesis and in vitro antibacterial activity of fluoroquinolone derivatives containing 3-(N′-alkoxycarbamimidoyl)-4-(alkoxyimino) pyrrolidines Fulltext Access 9 Pages 2010
Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis Fulltext Access 9 Pages 2010
Crystal structures, DNA-binding and cytotoxic activities studies of Cu(II) complexes with 2-oxo-quinoline-3-carbaldehyde Schiff-bases Fulltext Access 9 Pages 2010
Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors Fulltext Access 9 Pages 2010
Studies on quinones. Part 46. Synthesis and in vitro antitumor evaluation of aminopyrimidoisoquinolinequinones Fulltext Access 9 Pages 2010
Synthesis and biological evaluation of some 1,3,4-oxadiazole derivatives Fulltext Access 9 Pages 2010
Structure activity relationship studies of imidazo[1,2-a]pyrazine derivatives against cancer cell lines Fulltext Access 9 Pages 2010
Chemometric modeling of free radical scavenging activity of flavone derivatives Fulltext Access 9 Pages 2010