α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis Fulltext Access 7 Pages 2006
Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells Fulltext Access 7 Pages 2006
Fen1 does not control somatic hypermutability of the (CTG)n · (CAG)n repeat in a knock-in mouse model for DM1 Fulltext Access 7 Pages 2006
Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng Fulltext Access 7 Pages 2006
Normal mode analysis as a prerequisite for drug design: Application to matrix metalloproteinases inhibitors Fulltext Access 7 Pages 2006
Compositional properties of human cDNA libraries: Practical implications Fulltext Access 7 Pages 2006
Endothelin-1 inhibits adipogenesis: Role of phosphorylation of Akt and ERK1/2 Fulltext Access 7 Pages 2006
Occurrence of A-kinase anchor protein and associated cAMP-dependent protein kinase in the inner compartment of mammalian mitochondria Fulltext Access 7 Pages 2006
Differential protein distributions define two sub-compartments of the mitochondrial inner membrane in yeast Fulltext Access 7 Pages 2006
A single lysyl residue defines the binding specificity of a human odorant-binding protein for aldehydes Fulltext Access 7 Pages 2006
Suppression of inducible nitric oxide synthase by 10–23 DNAzymes in murine macrophage Fulltext Access 7 Pages 2006
Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism Fulltext Access 7 Pages 2006
Involvement of I2PP2A in the abnormal hyperphosphorylation of tau and its reversal by Memantine Fulltext Access 7 Pages 2006
The role of the N-terminal domain of chloroplast targeting peptides in organellar protein import and miss-sorting Fulltext Access 7 Pages 2006
A novel function for a ubiquitous plant enzyme pectin methylesterase: The enhancer of RNA silencing Fulltext Access 7 Pages 2006
Isolation and characterisation of conomap-Vt, a d-amino acid containing excitatory peptide from the venom of a vermivorous cone snail Fulltext Access 7 Pages 2006
Branchio-oto-renal syndrome associated mutations in Eyes Absent 1 result in loss of phosphatase activity Fulltext Access 7 Pages 2006
A novel nuclear-localized protein with special adenylate kinase properties from Caenorhabditis elegans Fulltext Access 7 Pages 2006
Mapping the essential structures of human ribosomal protein L7 for nuclear entry, ribosome assembly and function Fulltext Access 7 Pages 2006
Leucine zipper-like domain is required for tumor suppressor ING2-mediated nucleotide excision repair and apoptosis Fulltext Access 7 Pages 2006
Mechanism of action of the endo-(1 → 3)-α-glucanase MutAp from the mycoparasitic fungus Trichoderma harzianum Fulltext Access 7 Pages 2006
Traffic of prion protein between different compartments on the neuronal surface, and the propagation of prion disease Fulltext Access 7 Pages 2006
Adaptations in the lipid metabolism of the protozoan parasite Trypanosoma brucei Fulltext Access 7 Pages 2006
CHOP is involved in neuronal apoptosis induced by neurotrophic factor deprivation Fulltext Access 7 Pages 2006
J1 acylase, a glutaryl-7-aminocephalosporanic acid acylase from Bacillus laterosporus J1, is a member of the α/β-hydrolase fold superfamily Fulltext Access 7 Pages 2006
GD3-replica peptides selected from a phage peptide library induce a GD3 ganglioside antibody response Fulltext Access 7 Pages 2006
Anthocyanins from soybean seed coat inhibit the expression of TNF-α-induced genes associated with ischemia/reperfusion in endothelial cell by NF-κB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo Fulltext Access 7 Pages 2006
CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin α5β1 Fulltext Access 7 Pages 2006
The regulation of Bax by c-Jun N-terminal protein kinase (JNK) is a prerequisite to the mitochondrial-induced apoptotic pathway Fulltext Access 7 Pages 2006
Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner–Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase s Fulltext Access 7 Pages 2006
Inhibition of Na,K-ATPase-suppressive activity of translationally controlled tumor protein by sorting nexin 6 Fulltext Access 7 Pages 2006
Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid Fulltext Access 7 Pages 2006
Monocyte chemoattractant protein (MCP-1) is expressed in human cardiac cells and is differentially regulated by inflammatory mediators and hypoxia Fulltext Access 7 Pages 2006
Stretch-grown axons retain the ability to transmit active electrical signals Fulltext Access 7 Pages 2006
An essential role for salicylic acid in AtMYB30-mediated control of the hypersensitive cell death program in Arabidopsis Fulltext Access 7 Pages 2006
Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A2 Fulltext Access 7 Pages 2006
The relevance of the phosphatidylinositolphosphat-binding motif FRRGT of Atg18 and Atg21 for the Cvt pathway and autophagy Fulltext Access 7 Pages 2006
Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-α on hypothalamic insulin-dependent inhibition of food intake Fulltext Access 7 Pages 2006
CRY-DASH gene expression is under the control of the circadian clock machinery in tomato Fulltext Access 7 Pages 2006
Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich’s ataxia Fulltext Access 7 Pages 2006
The effects of charge-neutralizing mutation D6.30N on the functions of CB1 and CB2 cannabinoid receptors Fulltext Access 7 Pages 2006
JNK mediates TGF-β1-induced epithelial mesenchymal transdifferentiation of mouse transformed keratinocytes Fulltext Access 7 Pages 2006
Paneth cell antimicrobial peptides: Topographical distribution and quantification in human gastrointestinal tissues Fulltext Access 7 Pages 2006
Protein-based phylogenetic analysis by using hydropathy profile of amino acids Fulltext Access 7 Pages 2006
Two cysteine protease inhibitors, EhICP1 and 2, localized in distinct compartments, negatively regulate secretion in Entamoeba histolytica Fulltext Access 7 Pages 2006
Ump1 extends yeast lifespan and enhances viability during oxidative stress: Central role for the proteasome? Fulltext Access 7 Pages 2006
Effect of nitrosative stress on Schizosaccharomyces pombe: Inactivation of glutathione reductase by peroxynitrite Fulltext Access 7 Pages 2006
Depletion of cardiolipin and cytochrome c during ischemia increases hydrogen peroxide production from the electron transport chain Fulltext Access 7 Pages 2006
In vivo detection of free radicals induced by diethylnitrosamine in rat liver tissue Fulltext Access 7 Pages 2006
Redox-sensitive target detection in gibberellic acid-induced barley aleurone layer Fulltext Access 7 Pages 2006
Human cytochrome P450 reductase can act as a source of endogenous oxidative DNA damage and genetic instability Fulltext Access 7 Pages 2006
Plasma nitrite reserve and endothelial function in the human forearm circulation Fulltext Access 7 Pages 2006
Increased oxidative stress is correlated with mitochondrial dysfunction in chagasic patients Fulltext Access 7 Pages 2006
Up-regulation of γ-glutamyl transpeptidase activity following glutathione depletion has a compensatory rather than an inhibitory effect on mitochondrial complex I activity: implications for Parkinson's disease Fulltext Access 7 Pages 2006
Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy Fulltext Access 7 Pages 2006
Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells Fulltext Access 7 Pages 2006
Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: Implications for Parkinson's disease Fulltext Access 7 Pages 2006
Impact of high energy resolution detectors on the performance of a PET system dedicated to breast cancer imaging Fulltext Access 7 Pages 2006
Design and evaluation of new antipsoriatic antedrug candidates having 16-en-22-oxa-vitamin D3 structures Fulltext Access 7 Pages 2006
1-[3-Aminobenzisoxazol-5′-yl]-3-trifluoromethyl-6-[2′-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1′]-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of bloo Fulltext Access 7 Pages 2006
The influence of pH on the G-quadruplex binding selectivity of perylene derivatives Fulltext Access 7 Pages 2006
Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: Synthesis and biological evaluation Fulltext Access 7 Pages 2006
Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849 Fulltext Access 7 Pages 2006
SAR of biphenyl carboxamide ligands of the human melanin-concentrating hormone receptor 1 (MCH R1): Discovery of antagonist SB-568849 Fulltext Access 7 Pages 2006
Inhibitors of VEGF receptors-1 and -2 based on the 2-((pyridin-4-yl)ethyl)pyridine template Fulltext Access 7 Pages 2006
Adapter protein NRBP associates with Jab1 and negatively regulates AP-1 activity Fulltext Access 7 Pages 2006
Biochemical and electron microscopic characterization of the F1F0 ATP Synthase from the hyperthermophilic eubacterium Aquifex aeolicus Fulltext Access 7 Pages 2006
Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor Fulltext Access 7 Pages 2006
CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis Fulltext Access 7 Pages 2006
SECRET AGENT, an Arabidopsis thaliana O-GlcNAc transferase, modifies the Plum pox virus capsid protein Fulltext Access 7 Pages 2006
Mapping of two O-GlcNAc modification sites in the capsid protein of the potyvirus Plum pox virus Fulltext Access 7 Pages 2006
Respective importance of protein folding and glycosylation in the thermal stability of recombinant feruloyl esterase A Fulltext Access 7 Pages 2006
The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy Fulltext Access 7 Pages 2006
New ligand-based approach for the discovery of antitrypanosomal compounds Fulltext Access 7 Pages 2006
Oxidant stress and skeletal muscle glucose transport: Roles of insulin signaling and p38 MAPK Fulltext Access 7 Pages 2006
Mechanism by which avenanthramide-c, a polyphenol of oats, blocks cell cycle progression in vascular smooth muscle cells Fulltext Access 7 Pages 2006
Protein modification caused by a high dose of gamma irradiation in cryo-sterilized plasma: Protective effects of ascorbate Fulltext Access 7 Pages 2006
Reactivity of carbon nanotubes: Free radical generation or scavenging activity? Fulltext Access 7 Pages 2006
Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes Fulltext Access 7 Pages 2006
Increased urinary excretion of 8-iso-prostaglandin F2α in patients with HFE-related hemochromatosis: A case-control study Fulltext Access 7 Pages 2006
Low-dose intravenous nitrite improves hemodynamics in a canine model of acute pulmonary thromboembolism Fulltext Access 7 Pages 2006