Self-aggregation of synthetic zinc chlorophyll derivative possessing a perfluoroalkyl group in a fluorinated solvent Fulltext Access 7 Pages 2006
Novel fluorescent markers for hypoxic cells of naphthalimides with two heterocyclic side chains for bioreductive binding Fulltext Access 7 Pages 2006
Synthesis of 7-oxo-7H-naphtho[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines Fulltext Access 7 Pages 2006
Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases Fulltext Access 7 Pages 2006
Photodynamic inactivation of Escherichia coli immobilized on agar surfaces by a tricationic porphyrin Fulltext Access 7 Pages 2006
Monometallic complexes of 1,4,7,10-tetraazacyclododecane containing an imidazolium side: Synthesis, characterization, and their interaction with plasmid DNA Fulltext Access 7 Pages 2006
3′-Fluoro-3′-deoxy-5′-noraristeromycin derivatives: Synthesis and antiviral analysis Fulltext Access 7 Pages 2006
Design, synthesis, and biological evaluation of 1,2,3-trisubstituted-1,4-dihydrobenzo[g]quinoxaline-5,10-diones and related compounds as antifungal and antibacterial agents Fulltext Access 7 Pages 2006
Oxazolones: New tyrosinase inhibitors; synthesis and their structure–activity relationships Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of 5-arylamino-1H-benzo[d]imidazole-4,7-diones as inhibitor of endothelial cell proliferation Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of new spin-labeled derivatives of podophyllotoxin Fulltext Access 7 Pages 2006
Novel α-aminophosphonic acids. Design, characterization, and biological activity Fulltext Access 7 Pages 2006
Effective discrimination of antimalarial potency of artemisinin compounds based on quantum chemical calculations of their reaction mechanism Fulltext Access 7 Pages 2006
Structure–activity relationships of substituted N-benzyl piperidines in the GBR series: Synthesis of 4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(2-trifluoromethylbenzyl)piperidine, an allosteric modulator of the serotonin transporter Fulltext Access 7 Pages 2006
Synthesis of 8-geranyloxypsoralen analogues and their evaluation as inhibitors of CYP3A4 Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of (2S)- and (2R)-2-(3′-phosphonobicyclo[1.1.1]pentyl)glycines as novel group III selective metabotropic glutamate receptor ligands Fulltext Access 7 Pages 2006
Synthesis and high-throughput evaluation of triskelion uracil libraries for inhibition of human dUTPase and UNG2 Fulltext Access 7 Pages 2006
Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29 Fulltext Access 7 Pages 2006
A 9-cis-epoxycarotenoid dioxygenase inhibitor for use in the elucidation of abscisic acid action mechanisms Fulltext Access 7 Pages 2006
Structure–activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia–reperfusion injury Fulltext Access 7 Pages 2006
Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium Fulltext Access 7 Pages 2006
DNA sequence recognition in the minor groove by hairpin microgonotropens Fulltext Access 7 Pages 2006
Inhibitors of VEGF receptors-1 and -2 based on the 2-((pyridin-4-yl)ethyl)pyridine template Fulltext Access 7 Pages 2006
New ligand-based approach for the discovery of antitrypanosomal compounds Fulltext Access 7 Pages 2006
3D-QSAR studies of farnesyltransferase inhibitors: A comparative molecular field analysis approach Fulltext Access 7 Pages 2006
Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385 Fulltext Access 7 Pages 2006
Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies of a carboxyterminal truncated α-carbonic anhydrase from Helicobacter pylori Fulltext Access 7 Pages 2006
Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2′-Substituted triclosan derivatives Fulltext Access 7 Pages 2006
Design and synthesis of potent β-secretase (BACE1) inhibitors with P1′ carboxylic acid bioisosteres Fulltext Access 7 Pages 2006
Synthesis and evaluation of succinoyl-caprolactam γ-secretase inhibitors Fulltext Access 7 Pages 2006
Design, synthesis, antibacterial, and QSAR studies of myristic acid derivatives Fulltext Access 7 Pages 2006
In silico modeling of protein tyrosine phosphatase 1B inhibitors with cellular activity Fulltext Access 7 Pages 2006
Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure Fulltext Access 7 Pages 2006
DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine Fulltext Access 7 Pages 2006
Fish venom (Pterios volitans) peptide reduces tumor burden and ameliorates oxidative stress in Ehrlich's ascites carcinoma xenografted mice Fulltext Access 7 Pages 2006
99mTc-labeling of colchicine using [99mTc(CO)3(H2O)3]+ and [99mTcN]2+ core for the preparation of potential tumor-targeting agents Fulltext Access 7 Pages 2006
Metabolic conversion of 24-methyl-Δ25-cholesterol to 24-methylcholesterol in higher plants Fulltext Access 7 Pages 2006
Steroidal saponins from Calamus insignis, and their cell growth and cell cycle inhibitory activities Fulltext Access 7 Pages 2006
Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity Fulltext Access 7 Pages 2006
C-Glycoside analogues of β-galactosylceramide with a simple ceramide substitute: Synthesis and binding to HIV-1 gp120 Fulltext Access 7 Pages 2006
QSAR study on para-substituted aromatic sulfonamides as carbonic anhydrase II inhibitors using topological information indices Fulltext Access 7 Pages 2006
Synthesis and in vitro anti-hepatitis B virus activities of some ethyl 6-bromo-5-hydroxy-1H-indole-3-carboxylates Fulltext Access 7 Pages 2006
2,4-Dimethoxyphenylsemicarbazones with anticonvulsant activity against three animal models of seizures: Synthesis and pharmacological evaluation Fulltext Access 7 Pages 2006
Synthesis of 8-aminoadenosine 5′-(aminoalkyl phosphates), analogues of aminoacyl adenylates Fulltext Access 7 Pages 2006
Synthesis and antibacterial activity of some new 1-heteroaryl-5-amino-3H/methyl-4-phenylpyrazoles Fulltext Access 7 Pages 2006
Ribonucleic guanidine demonstrates an unexpected marked preference for complementary DNA rather than RNA Fulltext Access 7 Pages 2006
Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum Fulltext Access 7 Pages 2006
Activity of lupane triterpenoids from Maytenus species as inhibitors of nitric oxide and prostaglandin E2 Fulltext Access 7 Pages 2006
Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II) Fulltext Access 7 Pages 2006
Design, synthesis, and evaluation of novel galloyl pyrrolidine derivatives as potential anti-tumor agents Fulltext Access 7 Pages 2006
Spacer length and attaching position-dependent binding of synthesized protoberberine dimers to double-stranded DNA Fulltext Access 7 Pages 2006
Synthesis, anti-inflammatory and analgesic activity evaluation of some amidine and hydrazone derivatives Fulltext Access 7 Pages 2006
Modulation of paclitaxel transport by flavonoid derivatives in human breast cancer cells. Is there a correlation between binding affinity to NBD of P-gp and modulation of transport? Fulltext Access 7 Pages 2006
Synthesis and antiproliferative activity of N-substituted 2-amino-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazoles Fulltext Access 7 Pages 2006
Structural characteristics of novel symmetrical diaryl derivatives with nitrogenated functions. Requirements for cytotoxic activity Fulltext Access 7 Pages 2006
Synthesis and binding affinities of methylvesamicol analogs for the acetylcholine transporter and sigma receptor Fulltext Access 7 Pages 2006
Synthesis, antiproliferative and antifungal activities of some 2-(2,4-dihydroxyphenyl)-4H-3,1-benzothiazines Fulltext Access 7 Pages 2006
Furocoumarins from grapefruit juice and their effect on human CYP 3A4 and CYP 1B1 isoenzymes Fulltext Access 7 Pages 2006
Synthesis and in vitro anti-hepatitis B virus activities of some ethyl 5-hydroxy-1H-indole-3-carboxylates Fulltext Access 7 Pages 2006
Synthesis, stereochemical assignments, and biological activities of homoisoflavonoids Fulltext Access 7 Pages 2006
A novel naturally occurring tripyrrole with potential nuclease and anti-tumour properties Fulltext Access 7 Pages 2006
Towards NR2B receptor selective imaging agents for PET—synthesis and evaluation of N-[11C]-(2-methoxy)benzyl (E)-styrene-, 2-naphthyl- and 4-trifluoromethoxyphenylamidine Fulltext Access 7 Pages 2006
A novel free C-12 higher carbon sugar: asymmetric synthesis and reactivity with nucleophiles Fulltext Access 7 Pages 2006
Immobilisation of alcohol dehydrogenase from Lactobacillus brevis and its application in a plug-flow reactor Fulltext Access 7 Pages 2006
Synthesis, resolution, and absolute configuration of two novel and selective cyclooxygenase-2 inhibitors based on the 1,5-diarylpyrrole structure Fulltext Access 7 Pages 2006
Improved conditions for the asymmetric synthesis of α-amino acids using Cinchona-derived anthracenylmethyl ammonium salts as chiral phase-transfer organocatalysts Fulltext Access 7 Pages 2006
Structure–activity relationship for inhibition of 5α-reductase by triterpenoids isolated from Ganoderma lucidum Fulltext Access 7 Pages 2006
Enhancing effect of indirubin derivatives on 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced differentiation of HL-60 leukemia cells Fulltext Access 7 Pages 2006
Synthesis and DNA cleavage activities of mononuclear macrocyclic polyamine zinc(II), copper(II), cobalt(II) complexes which linked with uracil Fulltext Access 7 Pages 2006
New progesterone receptor antagonists: Phosphorus-containing 11β-aryl-substituted steroids Fulltext Access 7 Pages 2006
2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic α2 receptor ligands Fulltext Access 7 Pages 2006
Synthesis and in vitro antimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis(4-fluorophenyl)-methyl]piperazine Fulltext Access 7 Pages 2006
Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent Fulltext Access 7 Pages 2006
Comparative uptake, metabolism, and utilization of menaquinone-4 and phylloquinone in human cultured cell lines Fulltext Access 7 Pages 2006
The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase Fulltext Access 7 Pages 2006
Structures of new amphidinols with truncated polyhydroxyl chain and their membrane-permeabilizing activities Fulltext Access 7 Pages 2006
Synthesis and antiproliferative evaluation of certain pyrido[3,2-g]quinoline derivatives Fulltext Access 7 Pages 2006
Direct asymmetric aldol reaction catalyzed by simple prolinamide phenols Fulltext Access 7 Pages 2006
Synthesis of novel vasodilatory active nicotinate esters with amino acid function Fulltext Access 7 Pages 2006
Synthesis and evaluation of peptidic irreversible inhibitors of tissue transglutaminase Fulltext Access 7 Pages 2006
Structure of C-terminal fragment of merozoite surface protein-1 from Plasmodium vivax determined by homology modeling and molecular dynamics refinement Fulltext Access 7 Pages 2006
Synthesis and biological evaluation of a cyclic ether fluorinated noscapine analog Fulltext Access 7 Pages 2006
Antioxidant properties of violacein: Possible relation on its biological function Fulltext Access 7 Pages 2006
Effect of melanin on netilmicin-induced inhibition of collagen biosynthesis in human skin fibroblasts Fulltext Access 7 Pages 2006
The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides Fulltext Access 7 Pages 2006
Reduction of nonspecific binding proteins to self-assembled monolayer on gold surface Fulltext Access 7 Pages 2006
Search for dual function inhibitors for Alzheimer’s disease: Synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Aβ fibril formation inhibition capacity Fulltext Access 7 Pages 2006
Synthesis and in vitro antitumoral activity of new hydrazinopyrimidine-5-carbonitrile derivatives Fulltext Access 7 Pages 2006
QSAR studies of N1-(5-chloro-2-pyridyl)-2-{[4-(alkyl methyl)benzoyl]amino}-5-chlorobenzamide analogs Fulltext Access 7 Pages 2006