Structure–activity relationships of novel piperazines as antagonists for the melanocortin-4 receptor Fulltext Access 17 Pages 2005
Intramolecular charge-transfer-induced chemiluminescent decomposition of 1,2-dioxetanes bearing a phenylmethanide anion Fulltext Access 17 Pages 2005
Synthesis and evaluation of cis-hexahydropyrrolo[3,2-b]pyrrol-3-one peptidomimetic inhibitors of CAC1 cysteinyl proteinases Fulltext Access 17 Pages 2005
Synthesis and neuroprotective activity of analogues of glycyl-l-prolyl-l-glutamic acid (GPE) modified at the α-carboxylic acid Fulltext Access 17 Pages 2005
Mechanism and scope of salen bifunctional catalysts in asymmetric aldehyde and α-ketoester alkylation Fulltext Access 17 Pages 2005
Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid Fulltext Access 17 Pages 2005
Derivatives of 4,6-diamino-1,2-dihydro-2-phenyl-1,2,4-triazolo[4,3-a]quinoxalin-2H-1-one: potential antagonist ligands for imaging the A2A adenosine receptor by positron emission tomography (PET) Fulltext Access 17 Pages 2005
Synthesis of the B-ring of FR182877. Investigation of the reactions of 6-fumaryl 1,3,8-nonatrienes Fulltext Access 17 Pages 2005
Synthesis of novel, simplified, C-7 substituted eleutheside analogues with potent microtubule-stabilizing activity Fulltext Access 17 Pages 2005
Studies on the solvent dependence of the carbamic acid formation from Ï-(1-naphthyl)alkylamines and carbon dioxide Fulltext Access 17 Pages 2005
Plant-based anticancer molecules: A chemical and biological profile of some important leads Fulltext Access 17 Pages 2005
Molecular orbital approaches to the interpretation of organic mass spectra Fulltext Access 17 Pages 2005
Chemo- and stereoselectivity in titanium-mediated regioselective ring-opening reaction of epoxides at the more substituted carbon Fulltext Access 17 Pages 2005
The synthetic versatility of alkoxycarbonyl- and hydroxymethyl-piperazine-2,5-diones Fulltext Access 18 Pages 2005
Candida Rugosa lipase-catalyzed kinetic resolution of β-hydroxy-β-arylpropionates and δ-hydroxy-δ-aryl-β-oxo-pentanoates Fulltext Access 18 Pages 2005
Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles Fulltext Access 18 Pages 2005
Neuroprotectant effects of iso-osmolar d-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers Fulltext Access 18 Pages 2005
Manganese(III)-based oxidation of 2,4-piperidinediones in the presence of alkenes Fulltext Access 18 Pages 2005
Calorimetric Investigation of the Structural Relaxation of Amorphous Materials: Evaluating Validity of the Methodologies Fulltext Access 18 Pages 2005
Synthesis of proline-modified analogues of the neuroprotective agent glycyl-l-prolyl-glutamic acid (GPE) Fulltext Access 18 Pages 2005
Mechanism of protein stabilization by sugars during freeze-drying and storage: Native structure preservation, specific interaction, and/or immobilization in a glassy matrix? Fulltext Access 18 Pages 2005
Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases Fulltext Access 18 Pages 2005
Fast parallel molecular solutions for DNA-based supercomputing: the subset-product problem Fulltext Access 18 Pages 2005
Synthesis and biological evaluation of new tetrahydro-β-carbolines as inhibitors of the mitotic kinesin Eg5 Fulltext Access 18 Pages 2005
The importance of the amide bond nearest the thiol group in enzymatic reactions of coenzyme A Fulltext Access 18 Pages 2005
Gene selection for classification of cancers using probabilistic model building genetic algorithm Fulltext Access 18 Pages 2005
A comparison between two polarizability parameters in chemical–biological interactions Fulltext Access 18 Pages 2005
Synthesis and biological activity of novel 1,2-disubstituted benzene derivatives as factor Xa inhibitors Fulltext Access 19 Pages 2005
Heterogeneous Nucleation-Controlled Particulate Formation of Recombinant Human Platelet-Activating Factor Acetylhydrolase in Pharmaceutical Formulation Fulltext Access 19 Pages 2005
Anthranilic acid based CCK1 receptor antagonists: preliminary investigation on their second “touch point” Fulltext Access 19 Pages 2005
Synthesis, antitumour activity and structure-activity relationships of 5H-benzo[b]carbazoles Fulltext Access 19 Pages 2005
Structural and Analytical Characterization of Three Hydrates and an Anhydrate Form of Risedronate Fulltext Access 19 Pages 2005
A scientific paradigm for consciousness: A theory of premotor relations Fulltext Access 19 Pages 2005
Diastereodivergent synthesis of 2,5-diketopiperazine derivatives of β-carboline and isoquinoline from l-amino acids Fulltext Access 19 Pages 2005
Divergent syntheses of all 16 carbasugar stereoisomers via stereoconversion of carba-β-d-altropyranose derivatives Fulltext Access 19 Pages 2005
Supramolecular design of photocurrent-generating devices using fullerenes aimed at modelling artificial photosynthesis Fulltext Access 19 Pages 2005
A two-step four-component queuing cascade involving a Heck coupling, π-allylpalladium trapping and Diels–Alder reaction Fulltext Access 19 Pages 2005
Atom, atom-type, and total nonstochastic and stochastic quadratic fingerprints: a promising approach for modeling of antibacterial activity Fulltext Access 19 Pages 2005
Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics Fulltext Access 19 Pages 2005
To seek an approach toward the chemical conversion of C19-diterpenoid alkaloids to taxoids Fulltext Access 19 Pages 2005
Solution Behavior of IFN-β-1a: An Empirical Phase Diagram Based Approach Fulltext Access 19 Pages 2005
High speed development work by preparation of an “in-hand” library of NMR-quantified degradation products Fulltext Access 19 Pages 2005
Investigation into the structure–activity relationship of novel concentration dependent, dual action T-type calcium channel agonists/antagonists Fulltext Access 19 Pages 2005
Synthesis of (1R,4E,5S)-4-{[(E)-(azinyl)diazenyl]methylidene}-1,8,8-trimethyl-2-oxabicyclo[3.2.1]octan-3-ones and (1R,4R,5R)-4-([1,2,4]triazolo[4,3-x]azin-3-yl)-1,8,8-trimethyl-2-oxabicyclo[3.2.1]octan-3-ones Fulltext Access 19 Pages 2005
Pharmaceutical Liquid Crystals: The Relevance of Partially Ordered Systems Fulltext Access 20 Pages 2005
Selective Identification and Quantitative Analysis of Methionine Containing Peptides by Charge Derivatization and Tandem Mass Spectrometry Fulltext Access 20 Pages 2005
CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives Fulltext Access 20 Pages 2005
Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II Fulltext Access 20 Pages 2005
N-Methylthio β-lactam antibacterials: Effects of the C3/C4 ring substituents on anti-MRSA activity Fulltext Access 20 Pages 2005
New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design Fulltext Access 20 Pages 2005
Role of nanotechnology in targeted drug delivery and imaging: a concise review Fulltext Access 20 Pages 2005
Self-assembling nanoclusters in living systems: application for integrated photothermal nanodiagnostics and nanotherapy Fulltext Access 20 Pages 2005
Detection of 210Â kDa receptor protein for a leaf-movement factor by using novel photoaffinity probes Fulltext Access 20 Pages 2005
Dynamic modeling of biochemical reactions with application to signal transduction: principles and tools using Mathematica Fulltext Access 20 Pages 2005
Electrophilic amination of enolates with oxaziridines: effects of oxaziridine structure and reaction conditions Fulltext Access 20 Pages 2005
Synthesis and anticancer activity of new pyrrolocarbazoles and pyrrolo-β-carbolines Fulltext Access 21 Pages 2005
An assessment of the technique of simultaneous cooling in conjunction with microwave heating for organic synthesis Fulltext Access 21 Pages 2005
Robustness, evolvability, and optimality of evolutionary neural networks Fulltext Access 21 Pages 2005
Synthesis and photochromic reactivity of macromolecules incorporating four dithienylethene units Fulltext Access 21 Pages 2005
Synthesis and evaluation of two mannosamine-derived lactone-type inhibitors of snail β-mannosidase Fulltext Access 21 Pages 2005
Variations of solvent and substitution pattern in Pb(OAc)4 mediated domino reactions Fulltext Access 21 Pages 2005
Synthetic studies of the cyclic depsipeptides bearing the 3-amino-6-hydroxy-2-piperidone (Ahp) unit. Total synthesis of the proposed structure of micropeptin T-20 Fulltext Access 22 Pages 2005
Synthesis of lipid A analogues containing glucose instead of glucosamine and their LPS-antagonistic activities Fulltext Access 22 Pages 2005
IV-IVC considerations in the development of immediate-release oral dosage form Fulltext Access 22 Pages 2005
Synthetic utility of five-membered heterocycles-chiral functionalization and applications Fulltext Access 22 Pages 2005