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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Effect of piroxicam on lipid membranes: Drug encapsulation and gastric toxicity aspects
Fulltext Access 10 Pages 2017
Novel family of fused tricyclic [1,4]diazepines: Design, synthesis, crystal structures and molecular docking studies
Fulltext Access 10 Pages 2017
Stem cells in cardiovascular diseases: turning bad days into good ones
Fulltext Access 10 Pages 2017
A comprehensive review on polyelectrolyte complexes
Fulltext Access 10 Pages 2017
A simple and efficient approach for the synthesis of 2-aminated quinazoline derivatives via metal free oxidative annulation
Fulltext Access 10 Pages 2017
Network induction for epidemic profiles with a novel representation
Fulltext Access 10 Pages 2017
Energy conservation and maximal entropy production in enzyme reactions
Fulltext Access 10 Pages 2017
Formulation development and evaluation of antimicrobial polyherbal gel
Fulltext Access 10 Pages 2017
Toxicological potential of acyl glucuronides and its assessment
Fulltext Access 10 Pages 2017
The efficacy of probiotics as pharmacological treatment of cutaneous wounds: Meta-analysis of animal studies
Fulltext Access 10 Pages 2017
Archaeal lipids in oral delivery of therapeutic peptides
Fulltext Access 10 Pages 2017
Nanoparticle-macrophage interactions: A balance between clearance and cell-specific targeting
Fulltext Access 10 Pages 2017
Modeling and comparison of release profiles: Effect of the dissolution method
Fulltext Access 10 Pages 2017
The route from problem to solution in multistep continuous flow synthesis of pharmaceutical compounds
Fulltext Access 10 Pages 2017
The kynurenine pathway in schizophrenia and bipolar disorder
Fulltext Access 10 Pages 2017
Synthesis of an advanced intermediate enroute to thiomarinol antibiotics
Fulltext Access 10 Pages 2017
Transgenerational attenuation of opioid self-administration as a consequence of adolescent morphine exposure
Fulltext Access 10 Pages 2017
Towards prostate cancer gene therapy: Development of a chlorotoxin-targeted nanovector for toxic (melittin) gene delivery
Fulltext Access 10 Pages 2017
Clementine juice has the potential for drug interactions - In vitro comparison with grapefruit and mandarin juice
Fulltext Access 10 Pages 2017
Developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganization
Fulltext Access 10 Pages 2017
Formulation and development of Silybin loaded solid lipid nanoparticle enriched gel for irritant contact dermatitis
Fulltext Access 10 Pages 2017
Loperamide inhibits sodium channels to alleviate inflammatory hyperalgesia
Fulltext Access 10 Pages 2017
Alcohol and basal ganglia circuitry: Animal models
Fulltext Access 10 Pages 2017
Role of butter oil in brain targeted delivery of Quetiapine fumarate microemulsion via intranasal route
Fulltext Access 10 Pages 2017
Quality by design based silymarin nanoemulsion for enhancement of oral bioavailability
Fulltext Access 10 Pages 2017
Numerical simulation of Franz diffusion experiment: Application to drug loaded soft contact lenses
Fulltext Access 10 Pages 2017
Self-microemulsifying sustained-release pellet of Ginkgo biloba extract: Preparation, in vitro drug release and pharmacokinetics study in beagle dogs
Fulltext Access 10 Pages 2017
The clinical reasoning of Western herbal practitioners: A qualitative feasibility study
Fulltext Access 10 Pages 2017
Development of orodispersible films with selected Indonesian medicinal plant extracts
Fulltext Access 10 Pages 2017
3D printed liner for treatment of periprosthetic joint infections
Fulltext Access 10 Pages 2017
Original ArticleA drug-delivery strategy for overcoming drug resistance in breast cancer through targeting of oncofetal fibronectin
Fulltext Access 10 Pages 2017
Synthesis and cell imaging applications of fluorescent mono/di/tri-heterocyclyl-2,6-dicyanoanilines
Fulltext Access 10 Pages 2017
Immobilization of bacteriophage in wound-dressing nanostructure
Fulltext Access 10 Pages 2017
Pharmaceutical development of a generic corticoid semisolid formulation
Fulltext Access 10 Pages 2017
Near-infrared light-responsive nanoparticles with thermosensitive yolk-shell structure for multimodal imaging and chemo-photothermal therapy of tumor
Fulltext Access 10 Pages 2017
Synthesis and biological evaluation of novel non-racemic indole-containing allocolchicinoids
Fulltext Access 10 Pages 2017
Synthesis of desmosine-containing cyclic peptide for the possible elucidation of elastin crosslinking structure
Fulltext Access 10 Pages 2017
Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation
Fulltext Access 10 Pages 2017
Imaging the delivery of drug-loaded, iron-stabilized micelles
Fulltext Access 10 Pages 2017
Metallic nanoparticles to eradicate bacterial bone infection
Fulltext Access 10 Pages 2017
Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels
Fulltext Access 10 Pages 2017
Chitosan-based nanocomposites for the repair of bone defects
Fulltext Access 10 Pages 2017
Magnetic mapping of iron in rodent spleen
Fulltext Access 10 Pages 2017
Green synthesis and anticancer potential of chalcone linked-1,2,3-triazoles
Fulltext Access 10 Pages 2017
Fusaric acid and analogues as Gram-negative bacterial quorum sensing inhibitors
Fulltext Access 10 Pages 2017
Foot-and-mouth disease virus-like particles as integrin-based drug delivery system achieve targeting anti-tumor efficacy
Fulltext Access 10 Pages 2017
Imaging the glutamate receptor subtypes-Much achieved, and still much to do
Fulltext Access 10 Pages 2017
Graphical contents list
Fulltext Access 10 Pages 2017
Constrained cell penetrating peptides
Fulltext Access 10 Pages 2017
Size-dependent cellular uptake of exosomes
Fulltext Access 10 Pages 2017
Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery
Fulltext Access 10 Pages 2017
Biomimetic nanofibrous scaffolds for neural tissue engineering and drug development
Fulltext Access 10 Pages 2017
Schwann cells and neurite outgrowth from embryonic dorsal root ganglions are highly mechanosensitive
Fulltext Access 10 Pages 2017
Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation
Fulltext Access 11 Pages 2017
Differences in the coronal proteome acquired by particles depositing in the lungs of asthmatic versus healthy humans
Fulltext Access 11 Pages 2017
The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania
Fulltext Access 11 Pages 2017
Maximizing the Impact of Physiologically Based Oral Absorption Modeling and Simulation
Fulltext Access 11 Pages 2017
Industry Perspective on Contemporary Protein-Binding Methodologies: Considerations for Regulatory Drug-Drug Interaction and Related Guidelines on Highly Bound Drugs
Fulltext Access 11 Pages 2017
Elevated kynurenine pathway metabolism during neurodevelopment: Implications for brain and behavior
Fulltext Access 11 Pages 2017
Synthesis and cytotoxic activities of goniothalamins and derivatives
Fulltext Access 11 Pages 2017
Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins
Fulltext Access 11 Pages 2017
The journey from an allopathic to natural treatment approach: A scoping review of medical tourism and health systems
Fulltext Access 11 Pages 2017
An evaluation of central penetration from a peripherally administered oxytocin receptor selective antagonist in nonhuman primates
Fulltext Access 11 Pages 2017
Fabrication and characterization of film-forming voriconazole transdermal spray for the treatment of fungal infection
Fulltext Access 11 Pages 2017
A statistical study on the development of micro particulate sustained drug delivery system for Losartan potassium by 32 factorial design approach
Fulltext Access 11 Pages 2017
Carbon nanomaterials as versatile platforms for theranostic applications
Fulltext Access 11 Pages 2017
Evaluation of Granulated Lactose as a Carrier for Dry Powder Inhaler Formulations 2: Effect of Drugs and Drug Loading
Fulltext Access 11 Pages 2017
Aggregation-induced emission probes for cancer theranostics
Fulltext Access 11 Pages 2017
Therapeutic nanomaterials for cancer therapy and tissue regeneration
Fulltext Access 11 Pages 2017
Palladium-catalysed α-allylation of chiral sulfinimines derived from symmetric cyclic ketones
Fulltext Access 11 Pages 2017
Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions
Fulltext Access 11 Pages 2017
Lipophilic methylene violet analogues as modulators of mitochondrial function and dysfunction
Fulltext Access 11 Pages 2017
Chitosan cross-linked with poly(ethylene glycol)dialdehyde via reductive amination as effective controlled release carriers for oral protein drug delivery
Fulltext Access 11 Pages 2017
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents
Fulltext Access 11 Pages 2017
Recent updates of carbapenem antibiotics
Fulltext Access 11 Pages 2017
Optimization of substituted imidazobenzodiazepines as novel asthma treatments
Fulltext Access 11 Pages 2017
Discovery of efficient stimulators for adult hippocampal neurogenesis based on scaffolds in dragon's blood
Fulltext Access 11 Pages 2017
Rigid aromatic linking moiety in cationic lipids for enhanced gene transfection efficiency
Fulltext Access 11 Pages 2017
Synthesis and preliminary biological evaluation of new phenolic and catecholic dehydroamino acid derivatives
Fulltext Access 11 Pages 2017
Specific intramolecular aromatic CH insertion of diazosulfonamides
Fulltext Access 11 Pages 2017
Use of ligand-assisted click reactions for the rapid synthesis of novel 1,2,3-triazole pharmacophore-based 1,2,4-triazines and their benzo-fused analogues
Fulltext Access 11 Pages 2017
Aryne formation via the hexadehydro Diels-Alder reaction and their Ritter-type transformations catalyzed by a cationic silver complex
Fulltext Access 11 Pages 2017
Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases
Fulltext Access 11 Pages 2017
Reaction of 3-chloroquinoline-2,4-diones with ethanolamine and rearrangement of the reaction products
Fulltext Access 11 Pages 2017
Symmetrical and unsymmetrical incorporation of active biological monomers on the surface of phosphorus dendrimers
Fulltext Access 11 Pages 2017
Tumors arise from the excessive repair of damaged stem cells
Fulltext Access 11 Pages 2017
Importance of reversed-phase chromatographic parameters in predicting biopharmaceutical and pharmacokinetic descriptors on the group of androgen derivatives
Fulltext Access 11 Pages 2017
Evaluation of anti-diabetic activity of glycyrrhizin-loaded nanoparticles in nicotinamide-streptozotocin-induced diabetic rats
Fulltext Access 11 Pages 2017
Structural evidence of quercetin multi-target bioactivity: A reverse virtual screening strategy
Fulltext Access 11 Pages 2017
Chemometrics approach based on chromatographic behavior, in silico characterization and molecular docking study of steroid analogs with biomedical importance
Fulltext Access 11 Pages 2017
Extensive preclinical evaluation of an infliximab biosimilar candidate
Fulltext Access 11 Pages 2017
Melt extrusion vs. spray drying: The effect of processing methods on crystalline content of naproxen-povidone formulations
Fulltext Access 11 Pages 2017
Mixed poly(vinyl pyrrolidone)-based drug-loaded nanomicelles shows enhanced efficacy against pancreatic cancer cell lines
Fulltext Access 11 Pages 2017
Optimization of magnetic retention in the gastrointestinal tract: Enhanced bioavailability of poorly permeable drug
Fulltext Access 11 Pages 2017
Development and characterization of new functionalized polyurethanes for sustained and site-specific drug release in the gastrointestinal tract
Fulltext Access 11 Pages 2017
The synthesis of tamoxifen-loaded albumin nanoparticles by homogenizers: Optimization and in vitro characterization
Fulltext Access 11 Pages 2017
A novel approach for follicular delivery of minoxidil for treatment of alopecia
Fulltext Access 11 Pages 2017
Preparation, characterization and anti-inflammatory effects of curcumin loaded carboxymethyl cellulose acetate butyrate nanoparticles on adjuvant induced arthritis in rats
Fulltext Access 11 Pages 2017
Experimental studies on shock wave and particle dynamics in a needle-free drug delivery device
Fulltext Access 11 Pages 2017
A novel hybrid solid dispersion film coat as a moisture barrier for pharmaceutical applications
Fulltext Access 11 Pages 2017
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