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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Synthesis and anti-tumor evaluation of panaxadiol halogen-derivatives
Fulltext Access 18 Pages 2017
Viral vectors for therapy of neurologic diseases
Fulltext Access 18 Pages 2017
Synthetic and medicinal perspective of thiazolidinones: A review
Fulltext Access 18 Pages 2017
Prodrug approach: An overview of recent cases
Fulltext Access 18 Pages 2017
An integrated chemical biology approach reveals the mechanism of action of HIV replication inhibitors
Fulltext Access 18 Pages 2017
Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations
Fulltext Access 18 Pages 2017
Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound
Fulltext Access 18 Pages 2017
Isoxazole ring as a useful scaffold in a search for new therapeutic agents
Fulltext Access 18 Pages 2017
The role of neuroimmune signaling in alcoholism
Fulltext Access 18 Pages 2017
Lipid lowering agents of natural origin: An account of some promising chemotypes
Fulltext Access 18 Pages 2017
Biocompatibility of a new biodegradable polymer-hydroxyapatite composite for biomedical applications
Fulltext Access 18 Pages 2017
Different trends of teeth marks according to qi blood yin yang deficiency pattern in patients with chronic fatigue
Fulltext Access 18 Pages 2017
Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins
Fulltext Access 18 Pages 2017
Drug-target interactions that involve the replacement or displacement of magnesium ions
Fulltext Access 18 Pages 2017
Functional data analysis of single-trial auditory evoked potentials recorded in the awake rat
Fulltext Access 18 Pages 2017
Development of combretastatins as potent tubulin polymerization inhibitors
Fulltext Access 18 Pages 2017
Selective fluorescence sensing and quantification of uric acid by naphthyridine-based receptor in biological sample
Fulltext Access 18 Pages 2017
Comprehensive experimental investigation of mechanically induced 1,4-diazines synthesis in solid state
Fulltext Access 18 Pages 2017
Insects: an underrepresented resource for the discovery of biologically active natural products
Fulltext Access 18 Pages 2017
Direct synthesis of 3-halo-3-arylacrylonitriles from the addition of cyanoalkynes with alkaline metal halides
Fulltext Access 18 Pages 2017
Protein-based nanotoxicology assessment strategy
Fulltext Access 18 Pages 2017
High-Dose Metformin May Increase the Concentration of Atorvastatin in the Liver by Inhibition of Multidrug Resistance-Associated Protein 2
Fulltext Access 18 Pages 2017
Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development
Fulltext Access 18 Pages 2017
Unitary circular code motifs in genomes of eukaryotes
Fulltext Access 18 Pages 2017
Investigation of aryl isonitrile compounds with potent, broad-spectrum antifungal activity
Fulltext Access 19 Pages 2017
Identifying risk factors for bone mass transition states for postmenopausal osteoporosis
Fulltext Access 19 Pages 2017
Avoidance of food effect on oral absorption profile of itraconazole by self-micellizing solid dispersion approach
Fulltext Access 19 Pages 2017
Genetic studies of alcohol dependence in the context of the addiction cycle
Fulltext Access 19 Pages 2017
Nuclear data for production and medical application of radionuclides: Present status and future needs
Fulltext Access 19 Pages 2017
Stereochemistry abstracts
Fulltext Access 19 Pages 2017
A novel complexity-to-diversity strategy for the diversity-oriented synthesis of structurally diverse and complex macrocycles from quinine
Fulltext Access 19 Pages 2017
Integration of traditional and 'modern' medicine: Reflections on a visit to DPR Korea
Fulltext Access 19 Pages 2017
Inhibition of Malassezia globosa carbonic anhydrase with phenols
Fulltext Access 19 Pages 2017
Tubulin-binding dibenz[c,e]oxepines: Part 2.1 Structural variation and biological evaluation as tumour vasculature disrupting agents
Fulltext Access 19 Pages 2017
Synthesis of antimicrobial glucosamides as bacterial quorum sensing mechanism inhibitors
Fulltext Access 19 Pages 2017
Carba-d,l-allal- and -d,l-galactal-derived vinyl N-nosyl aziridines as useful tools for the synthesis of 4-deoxy-4-(N-nosylamino)-2,3-unsaturated-5a-carbasugars
Fulltext Access 19 Pages 2017
A single spike deteriorates synaptic conductance estimation
Fulltext Access 19 Pages 2017
Consensus nomenclature rules for radiopharmaceutical chemistry - Setting the record straight
Fulltext Access 19 Pages 2017
An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis
Fulltext Access 19 Pages 2017
Novel Budesonide Particles for Dry Powder Inhalation Prepared Using a Microfluidic Reactor Coupled With Ultrasonic Spray Freeze Drying
Fulltext Access 19 Pages 2017
Measurement and Accurate Interpretation of the Solubility of Pharmaceutical Salts
Fulltext Access 19 Pages 2017
Premature atherosclerosis in premenopausal women: Does cytokine balance play a role?
Fulltext Access 19 Pages 2017
Micro- and nano-carrier systems: The non-invasive and painless local administration strategies for disease therapy in mucosal tissues
Fulltext Access 19 Pages 2017
Synthesis and hybridization properties of oligonucleotide analogues with novel acyclic triazole internucleotide linkages
Fulltext Access 19 Pages 2017
Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic rings
Fulltext Access 19 Pages 2017
Strategies in the designing of prodrugs, taking into account the antiviral and anticancer compounds
Fulltext Access 19 Pages 2017
Covalent inhibitors design and discovery
Fulltext Access 19 Pages 2017
Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum
Fulltext Access 19 Pages 2017
From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease
Fulltext Access 19 Pages 2017
Novel carbazole sulfonamide derivatives of antitumor agent: Synthesis, antiproliferative activity and aqueous solubility
Fulltext Access 19 Pages 2017
Structure-activity relationship study and discovery of indazole 3-carboxamides as calcium-release activated calcium channel blockers
Fulltext Access 19 Pages 2017
Efficient synthesis of novel functionalized pyrazolo-pyranoquinoline and tetrahydrodibenzo-[1,8]naphthyridinone derivatives
Fulltext Access 19 Pages 2017
Structure-based analysis of Bacilli and plasmid dihydrofolate reductase evolution
Fulltext Access 19 Pages 2017
Synthesis of sulfonamides from azoles and sodium sulfinates at ambient temperature
Fulltext Access 19 Pages 2017
Effect of solvent model when probing protein dynamics with molecular dynamics
Fulltext Access 19 Pages 2017
Dynamic landscape models of coevolutionary games
Fulltext Access 19 Pages 2017
Graphical contents list
Fulltext Access 20 Pages 2017
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease
Fulltext Access 20 Pages 2017
Biosystem models, generated from a complex rule/reaction/influence network and from two functionality prototypes
Fulltext Access 20 Pages 2017
Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies
Fulltext Access 20 Pages 2017
Integrating clinical metabolomics-based biomarker discovery and clinical pharmacology to enable precision medicine
Fulltext Access 20 Pages 2017
Molecular nanoparticle-based gene delivery systems
Fulltext Access 20 Pages 2017
New erythrocyte-related delivery systems for biomedical applications
Fulltext Access 20 Pages 2017
Population Pharmacokinetics of Tobramycin Inhalation Solution in Pediatric Patients With Cystic Fibrosis
Fulltext Access 20 Pages 2017
Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics
Fulltext Access 20 Pages 2017
A review on the synthetic approaches of rivaroxaban: An anticoagulant drug
Fulltext Access 20 Pages 2017
Developing a Flexible Pediatric Dosage Form for Antiretroviral Therapy: A Fast-Dissolving Tablet
Fulltext Access 20 Pages 2017
The innovative applications of therapeutic nanostructures in dentistry
Fulltext Access 20 Pages 2017
A Study of Fasoracetam's Solid State Forms: A Potential Anti-Alzheimer Pharmaceutical
Fulltext Access 20 Pages 2017
A computational insight into cyclopropenone activated dehydration reaction of alcohols
Fulltext Access 20 Pages 2017
The effect of additional aeration of liquid on the atomization process for a pneumatic nebulizer
Fulltext Access 20 Pages 2017
A system of recurrent neural networks for modularising, parameterising and dynamic analysis of cell signalling networks
Fulltext Access 20 Pages 2017
Palladium-catalysed aminocarbonylation of diiodopyridines
Fulltext Access 20 Pages 2017
Using neurofeedback to manage long-term symptoms in cancer survivors: Results of a survey of neurofeedback providers
Fulltext Access 20 Pages 2017
Predicted phototoxicities of carbon nano-material by quantum mechanical calculations
Fulltext Access 20 Pages 2017
The relationship between adherence to the Mediterranean diet and body composition in Croatian university students
Fulltext Access 20 Pages 2017
The effects of patient-preferred music on anticipatory anxiety, post-procedural burn pain and relaxation level
Fulltext Access 20 Pages 2017
Cancer nanotheranostics: A review of the role of conjugated ligands for overexpressed receptors
Fulltext Access 20 Pages 2017
Steric buttressing in the Pauson-Khand reactions of benzyl enynes
Fulltext Access 20 Pages 2017
Novel propanamides as fatty acid amide hydrolase inhibitors
Fulltext Access 20 Pages 2017
Synthesis and antifungal activity of novel indole-replaced streptochlorin analogues
Fulltext Access 20 Pages 2017
Recent synthetic and medicinal perspectives of tryptanthrin
Fulltext Access 20 Pages 2017
Structure based drug design of Pim-1 kinase followed by pharmacophore guided synthesis of quinolone-based inhibitors
Fulltext Access 21 Pages 2017
Design, synthesis and biological evaluation of novel coumarin-based benzamides as potent histone deacetylase inhibitors and anticancer agents
Fulltext Access 21 Pages 2017
Study on the cycloaddition reactions of pyrrolotriazepine derivatives with nitrile oxides. Synthesis of new fused tricyclic ring systems
Fulltext Access 21 Pages 2017
Novel cinnamamide-dibenzylamine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease
Fulltext Access 21 Pages 2017
The Role of Physiologically Based Oral Absorption Modelling in Formulation Development Under a Quality by Design Paradigm
Fulltext Access 21 Pages 2017
Mechanisms of action and structure-activity relationships of cytotoxic flavokawain derivatives
Fulltext Access 21 Pages 2017
Three-component, one-pot synthesis of anthranilamide Schiff bases bearing 4-aminoquinoline moiety as Mycobacterium tuberculosis gyrase inhibitors
Fulltext Access 21 Pages 2017
Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis
Fulltext Access 21 Pages 2017
Current approaches to the treatment of Parkinson's Disease
Fulltext Access 21 Pages 2017
Add-on effect of Yu Ping Feng formula for childhood asthma: A meta-analysis of randomized controlled trials
Fulltext Access 21 Pages 2017
Efficiency of rate and latency coding with respect to metabolic cost and time
Fulltext Access 21 Pages 2017
Studies on diagnostic biomarkers and therapeutic mechanism of Alzheimer's disease through metabolomics and hippocampal proteomics
Fulltext Access 21 Pages 2017
Thermo-Optical Protein Characterization for Straightforward Preformulation Development
Fulltext Access 21 Pages 2017
Controlled and Localized Nitric Oxide Precursor Delivery From Chitosan Gels to Staphylococcus aureus Biofilms
Fulltext Access 21 Pages 2017
Synthesis and biological activity of peptide proline-boronic acids as proteasome inhibitors
Fulltext Access 21 Pages 2017
Treatment of rheumatoid arthritis by targeting macrophages through folic acid tailored superoxide dismutase and serratiopeptidase
Fulltext Access 21 Pages 2017
Isoskeletomerism as an intermediate concept for mediating between stereoisomerism and isomerism. A remedy for conceptual defects of organic chemistry
Fulltext Access 21 Pages 2017
Design, synthesis, and antiviral activities of 1,5-benzothiazepine derivatives containing pyridine moiety
Fulltext Access 21 Pages 2017
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