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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Microbial hydroxylation and glycosylation of pentacyclic triterpenes as inhibitors on tissue factor procoagulant activity
Fulltext Access 15 Pages 2017
Graphical abstract contents listing
Fulltext Access 15 Pages 2017
Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors
Fulltext Access 15 Pages 2017
Mechanisms contributing to cognitive deficits in cannabis users
Fulltext Access 15 Pages 2017
Synthesis and biological evaluation of novel chalcone derivatives as a new class of microtubule destabilizing agents
Fulltext Access 15 Pages 2017
Magnesium enhances opioid-induced analgesia - What we have learnt in the past decades?
Fulltext Access 15 Pages 2017
Mechanistic investigation of the negative food effect of modified release zolpidem
Fulltext Access 15 Pages 2017
Anti-tubercular drug discovery: in silico implications and challenges
Fulltext Access 15 Pages 2017
Synthesis and structure activity relationships of carbamimidoylcarbamate derivatives as novel vascular adhesion protein-1 inhibitors
Fulltext Access 15 Pages 2017
Stereo-controlled synthesis of functionalized tetrahydropyridines based on the cyanomethylation of 1,6-dihydropyridines and generation of anti-hepatitis C virus agents
Fulltext Access 15 Pages 2017
Targeting calcium signaling in cancer therapy
Fulltext Access 15 Pages 2017
Synthesis of 4-aminotetrahydropyran scaffolds for drug discovery
Fulltext Access 15 Pages 2017
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity
Fulltext Access 15 Pages 2017
Computational approach for the assessment of inhibitory potency against beta-amyloid aggregation
Fulltext Access 15 Pages 2017
Development of fluorine-18 labeled peptidic PET tracers for imaging active tissue transglutaminase
Fulltext Access 15 Pages 2017
Lewis acid-promoted cascade reaction for the synthesis of Michael acceptors and its application in a dimerization reaction
Fulltext Access 15 Pages 2017
Investigation of novel pharmacological chaperones for Gaucher Disease
Fulltext Access 15 Pages 2017
Review articleReviewing evidence for systematic transcriptional deletions, nucleotide exchanges, and expanded codons, and peptide clusters in human mitochondria
Fulltext Access 15 Pages 2017
Pharmaceutical Film Coating Catalog for Spectral Domain Optical Coherence Tomography
Fulltext Access 15 Pages 2017
Stereochemistry abstracts
Fulltext Access 15 Pages 2017
Bromination of quinoxaline and derivatives: Effective synthesis of some new brominated quinoxalines
Fulltext Access 15 Pages 2017
Graphical contents list
Fulltext Access 15 Pages 2017
Exploration of thioxothiazolidinone-sulfonate conjugates as a new class of aldehyde/aldose reductase inhibitors: A synthetic and computational investigation
Fulltext Access 15 Pages 2017
Effect of diseases on symbiotic systems
Fulltext Access 15 Pages 2017
Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications
Fulltext Access 15 Pages 2017
ReviewFoundationModels for drug absorption from the small intestine: where are we and where are we going?
Fulltext Access 15 Pages 2017
Contents (graphical abstracts and research highlights)
Fulltext Access 15 Pages 2017
Review articleGenetic coding and united-hypercomplex systems in the models of algebraic biology
Fulltext Access 16 Pages 2017
Development and evaluation of a cedrol-loaded nanostructured lipid carrier system for in vitro and in vivo susceptibilities of wild and drug resistant Leishmania donovani amastigotes
Fulltext Access 16 Pages 2017
Critical view on drug dissolution in artificial saliva: A possible use of in-line e-tongue measurements
Fulltext Access 16 Pages 2017
Pharmacological screening technologies for venom peptide discovery
Fulltext Access 16 Pages 2017
Novel simple fluorescent sensor for nickel ions
Fulltext Access 16 Pages 2017
Graphical abstract contents listing
Fulltext Access 16 Pages 2017
Cannabis-associated psychosis: Neural substrate and clinical impact
Fulltext Access 16 Pages 2017
The cannabinoid system and pain
Fulltext Access 16 Pages 2017
Orbitofrontal participation in sign- and goal-tracking conditioned responses: Effects of nicotine
Fulltext Access 16 Pages 2017
Tryptophan availability for kynurenine pathway metabolism across the life span: Control mechanisms and focus on aging, exercise, diet and nutritional supplements
Fulltext Access 16 Pages 2017
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases
Fulltext Access 16 Pages 2017
Design, synthesis and structure-activity relationship studies of novel free fatty acid receptor 1 agonists bearing amide linker
Fulltext Access 16 Pages 2017
Recent discoveries of anticancer flavonoids
Fulltext Access 16 Pages 2017
Information reduction in a reverberatory neuronal network through convergence to complex oscillatory firing patterns
Fulltext Access 16 Pages 2017
Mechanistic applications of click chemistry for pharmaceutical drug discovery and drug delivery
Fulltext Access 16 Pages 2017
Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics?
Fulltext Access 16 Pages 2017
Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering
Fulltext Access 16 Pages 2017
Physiologically Based Pharmacokinetic Modeling of Drug Transporters to Facilitate Individualized Dose Prediction
Fulltext Access 16 Pages 2017
Clinical Drug-Drug Interaction Evaluations to Inform Drug Use and Enable Drug Access
Fulltext Access 16 Pages 2017
Magnetic Resonance Imaging to Visualize Disintegration of Oral Formulations
Fulltext Access 16 Pages 2017
Stereochemistry abstracts
Fulltext Access 16 Pages 2017
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains
Fulltext Access 16 Pages 2017
Tetrazolylmethyl quinolines: Design, docking studies, synthesis, anticancer and antifungal analyses
Fulltext Access 16 Pages 2017
Convenient synthesis of memantine analogues containing a chiral cyclopropane skeleton as a sigma-1 receptor agonist
Fulltext Access 16 Pages 2017
Stereochemistry abstracts
Fulltext Access 16 Pages 2017
Novel celastrol derivatives with improved selectivity and enhanced antitumour activity: Design, synthesis and biological evaluation
Fulltext Access 16 Pages 2017
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
Fulltext Access 16 Pages 2017
Synthesis of 2-morpholinetetraphenylporphyrins and their photodynamic activities
Fulltext Access 16 Pages 2017
Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps
Fulltext Access 16 Pages 2017
Solvent free, catalyst free, microwave or grinding assisted synthesis of bis-cyclic imide derivatives and their evaluation for anticancer activity
Fulltext Access 16 Pages 2017
Synthesis and biological evaluation of novel quinazoline-sulfonamides as anti-cancer agents
Fulltext Access 16 Pages 2017
Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs
Fulltext Access 16 Pages 2017
Design, synthesis and biological evaluation of nitrogen-containing macrocyclic bisbibenzyl derivatives as potent anticancer agents by targeting the lysosome
Fulltext Access 16 Pages 2017
Design, synthesis, anti-inflammatory activity, and molecular docking studies of perimidine derivatives containing triazole
Fulltext Access 16 Pages 2017
Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease
Fulltext Access 16 Pages 2017
Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol
Fulltext Access 16 Pages 2017
Methyl propiolate and 3-butynone: Starting points for synthesis of amphiphilic 1,2,3-triazole peptidomimetics for antimicrobial evaluation
Fulltext Access 16 Pages 2017
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase
Fulltext Access 17 Pages 2017
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes
Fulltext Access 17 Pages 2017
Design, synthesis and fungicidal activity of novel 2-substituted aminocycloalkylsulfonamides
Fulltext Access 17 Pages 2017
Design, synthesis and antifungal activity of novel fenfuram-diarylamine hybrids
Fulltext Access 17 Pages 2017
Molecular modeling, simulation and docking study of ebola virus glycoprotein
Fulltext Access 17 Pages 2017
Linker structure-activity relationships in fluorodeoxyglucose chlorambucil conjugates for tumor-targeted chemotherapy
Fulltext Access 17 Pages 2017
Evidence-based drug treatment for special patient populations through model-based approaches
Fulltext Access 17 Pages 2017
The influence of drug distribution and drug-target binding on target occupancy: The rate-limiting step approximation
Fulltext Access 17 Pages 2017
Review ArticleFullerene nanoparticle in dermatological and cosmetic applications
Fulltext Access 17 Pages 2017
Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells
Fulltext Access 17 Pages 2017
Aerosol Production by Vibrating Membrane Technology: Analysis of the Electrolyte Effect on Generated Droplet Size and Nebulizer Output Rate
Fulltext Access 17 Pages 2017
Nanocarriers in cancer clinical practice: a pharmacokinetic issue
Fulltext Access 17 Pages 2017
One-pot synthesis of tricyclo-1,4-benzoxazines via visible-light photoredox catalysis in continuous flow
Fulltext Access 17 Pages 2017
Selective photocytotoxicity of anthrols on cancer stem-like cells: The effect of quinone methides or reactive oxygen species
Fulltext Access 17 Pages 2017
A global optimization algorithm inspired in the behavior of selfish herds
Fulltext Access 17 Pages 2017
Heck arylation of allyl alcohol catalyzed by Pd(0) nanoparticles
Fulltext Access 17 Pages 2017
Contents (graphical abstracts and research highlights)
Fulltext Access 17 Pages 2017
Amino derivatives of platanic acid act as selective and potent inhibitors of butyrylcholinesterase
Fulltext Access 17 Pages 2017
The reliability and validity of instruments measuring pattern identification in Korean medicine: A systematic review
Fulltext Access 17 Pages 2017
Indigenous knowledge of the use of medicinal plants in the North-West of Morocco and their biological activities
Fulltext Access 17 Pages 2017
Satisfied naturopathic practitioners? Results from a job satisfaction survey in the federal state of Schleswig-Holstein, Germany
Fulltext Access 17 Pages 2017
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents
Fulltext Access 17 Pages 2017
Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitors
Fulltext Access 17 Pages 2017
Recent developments in biological activities of indanones
Fulltext Access 17 Pages 2017
Electromagnetic fields may act via calcineurin inhibition to suppress immunity, thereby increasing risk for opportunistic infection: Conceivable mechanisms of action
Fulltext Access 17 Pages 2017
Review on asymmetric synthetic methodologies for chiral isoquinuclidines; 2008 to date
Fulltext Access 17 Pages 2017
Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer
Fulltext Access 17 Pages 2017
Maternal alcohol binge drinking induces persistent neuroinflammation associated with myelin damage and behavioural dysfunctions in offspring mice
Fulltext Access 17 Pages 2017
Synthesis and biological evaluation of chalcone, dihydrochalcone, and 1,3-diarylpropane analogs as anti-inflammatory agents
Fulltext Access 17 Pages 2017
Synthesis of extended conjugated indolyl chalcones as potent anti-breast cancer, anti-inflammatory and antioxidant agents
Fulltext Access 17 Pages 2017
Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders
Fulltext Access 17 Pages 2017
Density functional theory study of defective silicenes as anode materials for lithium ion batteries
Fulltext Access 17 Pages 2017
Noninvasive nanoparticle strategies for brain tumor targeting
Fulltext Access 17 Pages 2017
Functional data analysis of single-trial auditory evoked potentials recorded in the awake rat
Fulltext Access 18 Pages 2017
Development of combretastatins as potent tubulin polymerization inhibitors
Fulltext Access 18 Pages 2017
Synthesis and anti-tumor evaluation of panaxadiol halogen-derivatives
Fulltext Access 18 Pages 2017
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