The Role of Physiologically Based Oral Absorption Modelling in Formulation Development Under a Quality by Design Paradigm Fulltext Access 21 Pages 2017
Thermo-Optical Protein Characterization for Straightforward Preformulation Development Fulltext Access 21 Pages 2017
Novel cinnamamide-dibenzylamine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease Fulltext Access 21 Pages 2017
Three-component, one-pot synthesis of anthranilamide Schiff bases bearing 4-aminoquinoline moiety as Mycobacterium tuberculosis gyrase inhibitors Fulltext Access 21 Pages 2017
Analysis of network motifs in cellular regulation: Structural similarities, input-output relations and signal integration Fulltext Access 21 Pages 2017
How to train your inhibitor: Design strategies to overcome resistance to Epidermal Growth Factor Receptor inhibitors Fulltext Access 21 Pages 2017
Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis Fulltext Access 21 Pages 2017
Structure based drug design of Pim-1 kinase followed by pharmacophore guided synthesis of quinolone-based inhibitors Fulltext Access 21 Pages 2017
Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles Fulltext Access 21 Pages 2017
Treatment of rheumatoid arthritis by targeting macrophages through folic acid tailored superoxide dismutase and serratiopeptidase Fulltext Access 21 Pages 2017
Studies on diagnostic biomarkers and therapeutic mechanism of Alzheimer's disease through metabolomics and hippocampal proteomics Fulltext Access 21 Pages 2017
An asymmetric synthesis of febrifugine, halofuginone and their hemiketal isomers Fulltext Access 22 Pages 2017
New generation of docking programs: Supercomputer validation of force fields and quantum-chemical methods for docking Fulltext Access 22 Pages 2017
Methyllysine binding domains: Structural insight and small molecule probe development Fulltext Access 22 Pages 2017
Computational study to understand the energy transfer pathways within amicyanin Fulltext Access 22 Pages 2017
Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furans Fulltext Access 22 Pages 2017
Inverse Bayesian inference as a key of consciousness featuring a macroscopic quantum logical structure Fulltext Access 22 Pages 2017
ReviewFoundationTechnological advances and proteomic applications in drug discovery and target deconvolution: identification of the pleiotropic effects of statins Fulltext Access 22 Pages 2017
Higher serum lycopene is associated with reduced prevalence of hypertension in overweight or obese adults Fulltext Access 22 Pages 2017
Design, development and characterization of transdermal patch of methadone Fulltext Access 22 Pages 2017
Corticosteroid treatment exacerbates bone osteopenia in mice with gonadal hormone deficiency-induced osteoporosis Fulltext Access 22 Pages 2017
Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors Fulltext Access 22 Pages 2017
A molecular dynamic study on the dissociation mechanism of SI methane hydrate in inorganic salt aqueous solutions Fulltext Access 22 Pages 2017
Hybrid drug combination: Combination of ferulic acid and metformin as anti-diabetic therapy Fulltext Access 22 Pages 2017
Quantitative microscopy-based measurements of circulating nanoparticle concentration using microliter blood volumes Fulltext Access 22 Pages 2017
Impact of Sterilization Method on Protein Aggregation and Particle Formation in Polymer-Based Syringes Fulltext Access 22 Pages 2017
Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation Fulltext Access 22 Pages 2017
Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents Fulltext Access 22 Pages 2017
Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study Fulltext Access 22 Pages 2017
Prediction of Human Pharmacokinetic Profile After Transdermal Drug Application Using Excised Human Skin Fulltext Access 22 Pages 2017
Synthesis, characterization and biological studies of Schiff bases derived from heterocyclic moiety Fulltext Access 22 Pages 2017
Evaluation of Vaginal Drug Levels and Safety of a Locally Administered Glycerol Monolaurate Cream in Rhesus Macaques Fulltext Access 23 Pages 2017
One-step versus two-step mechanism of Diels-Alder reaction of 1-chloro-1-nitroethene with cyclopentadiene and furan Fulltext Access 23 Pages 2017
Antibacterial potential of Urtica dioica and Lavandula angustifolia extracts against methicillin resistant Staphylococcus aureus isolated from diabetic foot ulcers Fulltext Access 23 Pages 2017
Artesunate-quercetin/luteolin dual drug nanofacilitated synergistic treatment for malaria: A plausible approach to overcome artemisinin combination therapy resistance Fulltext Access 23 Pages 2017
The effect of binder concentration and dry mixing time on granules, tablet characteristics and content uniformity of low dose drug in high shear wet granulation Fulltext Access 23 Pages 2017
The Binary System of Ibuprofen-Nicotinamide Under Nanoscale Confinement: From Cocrystal to Coamorphous State Fulltext Access 23 Pages 2017
Interrelationships Between Structure and the Properties of Amorphous Solids of Pharmaceutical Interest Fulltext Access 23 Pages 2017
Recent Advances in Lipid-Based Vesicles and Particulate Carriers for Topical and Transdermal Application Fulltext Access 23 Pages 2017
Toll-like receptor signalling as a cannabinoid target in Multiple Sclerosis Fulltext Access 23 Pages 2017
Non-maturational covariates for dynamic systems pharmacology models in neonates, infants, and children: Filling the gaps beyond developmental pharmacology Fulltext Access 23 Pages 2017
Novel salicylanilides from 4,5-dihalogenated salicylic acids: Synthesis, antimicrobial activity and cytotoxicity Fulltext Access 23 Pages 2017
A one-pot laccase-catalysed synthesis of coumestan derivatives and their anticancer activity Fulltext Access 23 Pages 2017
Folic acid conjugates with photosensitizers for cancer targeting in photodynamic therapy: Synthesis and photophysical properties Fulltext Access 23 Pages 2017
Theoretical study on the alkylation of o-xylene with styrene in AlCl3-ionic liquid catalytic system Fulltext Access 23 Pages 2017
Thiadiazolodiazepine analogues as a new class of neuromuscular blocking agents: Synthesis, biological evaluation and molecular modeling study Fulltext Access 23 Pages 2017
Synthesis and pre-clinical studies of new amino-acid ester thiazolide prodrugs Fulltext Access 23 Pages 2017
Synthesis and biological evaluation of novel isoxazolines linked via piperazine to 2- benzoisothiazoles as potent apoptotic agents Fulltext Access 23 Pages 2017
Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach Fulltext Access 23 Pages 2017
New bithiazolyl hydrazones: Novel synthesis, characterization and antitubercular evaluation Fulltext Access 23 Pages 2017
Novel 2-arylazoimidazole derivatives as inhibitors of Trypanosoma cruzi proliferation: Synthesis and evaluation of their biological activity Fulltext Access 23 Pages 2017
Atomic scale modeling of electrically doped p-i-n FET from adenine based single wall nanotube Fulltext Access 23 Pages 2017
Protocol for fast screening of multi-target drug candidates: Application to Alzheimer's disease Fulltext Access 23 Pages 2017
Design of virtual reality training program for prevention of falling in the elderly: A pilot study on complex versus balance exercises Fulltext Access 23 Pages 2017
Host-guest interactions between sildenafil and cyclodextrins: Spectrofluorometric study and molecular dynamic modeling Fulltext Access 23 Pages 2017
Recent advances in the enantioselective 1,3-dipolar cycloaddition of azomethine ylides and dipolarophiles Fulltext Access 24 Pages 2017
Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment Fulltext Access 24 Pages 2017
Focused Ultrasound-Triggered Release of Tyrosine Kinase Inhibitor From Thermosensitive Liposomes for Treatment of Renal Cell Carcinoma Fulltext Access 24 Pages 2017
Bio-based polyurethane for tissue engineering applications: How hydroxyapatite nanoparticles influence the structure, thermal and biological behavior of polyurethane composites Fulltext Access 24 Pages 2017
Design, synthesis and biological evaluation of novel nitric oxide-donating protoberberine derivatives as antitumor agents Fulltext Access 24 Pages 2017
Differential scanning calorimetry and thin layer chromatography: Emerging tools for predicting stability of herbal products Fulltext Access 24 Pages 2017
Design, synthesis and bioevaluation of antitubulin agents carrying diaryl-5,5-fused-heterocycle scaffold Fulltext Access 24 Pages 2017
Fast dissolving drug-drug eutectics with improved compressibility and synergistic effects Fulltext Access 24 Pages 2017
Synthesis, surfactant properties and antimicrobial activities of methyl glycopyranoside ethers Fulltext Access 24 Pages 2017
Methotrexate pharmacogenetics in Uruguayan adults with hematological malignant diseases Fulltext Access 24 Pages 2017
The synthesis and evaluation of new butadiene derivatives as tubulin polymerization inhibitors Fulltext Access 24 Pages 2017
Mimicking the contractions of a human stomach and their effect on pharmaceuticals Fulltext Access 24 Pages 2017
Lack of eye discipline during headers in high school girls soccer: A possible mechanism for increased concussion rates Fulltext Access 24 Pages 2017
Synthesis of a novel functionalized tricyclic pyrimidine-fused 1,5-benzodiazepine library Fulltext Access 24 Pages 2017
Nucleophilic substitution at phosphorus: stereochemistry and mechanisms Fulltext Access 24 Pages 2017
Free radicals and polyphenols: The redox chemistry of neurodegenerative diseases Fulltext Access 24 Pages 2017
Aged macular degeneration: current therapeutics for management and promising new drug candidates Fulltext Access 24 Pages 2017
Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet Fulltext Access 25 Pages 2017
Design, synthesis and biological evaluation of bambuterol analogues as novel inhibitors of butyrylcholinesterase Fulltext Access 25 Pages 2017
Impact of pharmacokinetic-pharmacodynamic modelling in early clinical drug development Fulltext Access 25 Pages 2017
Computational study of the 1,3-dipolar cycloaddition between methyl 2-trifluorobutynoate and substituted azides in terms of reactivity indices and activation parameters Fulltext Access 25 Pages 2017
When a model becomes the real thing: A neuro-cognitive account of 'demonic' possession Fulltext Access 25 Pages 2017
Molecular Dynamics of Amorphous Sulfamethazine With Structurally Related Sulfonamide Impurities Evaluated Using Thermal Analysis Fulltext Access 25 Pages 2017
Enantioselective organocatalytic conjugate addition of organoboron nucleophiles Fulltext Access 25 Pages 2017
Angiogenesis and cancer stem cells: New perspectives on therapy of ovarian cancer Fulltext Access 25 Pages 2017
Variable Threshold Method for Determining the Boundaries of Imaged Subvisible Particles Fulltext Access 25 Pages 2017
Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation Fulltext Access 25 Pages 2017
Impact of Magnetic Stirring on Stainless Steel Integrity: Effect on Biopharmaceutical Processing Fulltext Access 25 Pages 2017
Design, synthesis and biological evaluation of novel hydroxamates and 2-aminobenzamides as potent histone deacetylase inhibitors and antitumor agents Fulltext Access 25 Pages 2017
Transporters Involved in Metformin Pharmacokinetics and Treatment Response Fulltext Access 25 Pages 2017
An insight into the biological activities of heterocyclic-fatty acid hybrid molecules Fulltext Access 25 Pages 2017