Microwave assisted synthesis of novel hybrid tacrine-sulfonamide derivatives and investigation of their antioxidant and anticholinesterase activities Fulltext Access 30 Pages 2017
Inhibition of Candida albicans biofilm by pure selenium nanoparticles synthesized by pulsed laser ablation in liquids Fulltext Access 30 Pages 2017
Nanoparticle delivery of chemotherapy combination regimen improves the therapeutic efficacy in mouse models of lung cancer Fulltext Access 30 Pages 2017
Paclitaxel-Loaded Magnetic Nanoparticles: Synthesis, Characterization, and Application in Targeting Fulltext Access 30 Pages 2017
The role of hyaluronan as a drug carrier to enhance the bioavailability of extended release ophthalmic formulations. Hyaluronan-timolol ionic complexes as a model case Fulltext Access 30 Pages 2017
Model Systems for Studying the Role of Canalicular Efflux Transporters in Drug-Induced Cholestatic Liver Disease Fulltext Access 30 Pages 2017
Re-evaluating the presumed superiority of amorphous nanoparticles over amorphous microscale solid dispersion in solubility enhancement of poorly soluble drugs Fulltext Access 30 Pages 2017
Design, synthesis, molecular docking, anti-Proteus mirabilis and urease inhibition of new fluoroquinolone carboxylic acid derivatives Fulltext Access 30 Pages 2017
Diurnal variation in the pharmacokinetics and brain distribution of morphine and its major metabolite Fulltext Access 30 Pages 2017
Influence of chair-based yoga on salivary anti-microbial proteins, functional fitness, perceived stress and well-being in older women: A pilot randomized controlled trial Fulltext Access 30 Pages 2017
Development of Maltodextrin-Based Immediate-Release Tablets Using an Integrated Twin-Screw Hot-Melt Extrusion and Injection-Molding Continuous Manufacturing Process Fulltext Access 30 Pages 2017
Parameters Affecting the Enhanced Permeability and Retention Effect: The Need for Patient Selection Fulltext Access 30 Pages 2017
Jet-vortex spray freeze drying for the production of inhalable lyophilisate powders Fulltext Access 30 Pages 2017
A Mechanism-Based Pharmacokinetic Enzyme Turnover Model for Dichloroacetic Acid Autoinhibition in Rats Fulltext Access 30 Pages 2017
Impact of Formulation Properties and Process Parameters on the Dispensing and Depositioning of Drug Nanosuspensions Using Micro-Valve Technology Fulltext Access 30 Pages 2017
Hot-melt extrusion as a continuous manufacturing process to form ternary cyclodextrin inclusion complexes Fulltext Access 30 Pages 2017
Effect of alkylaminophenols on growth inhibition and apoptosis of bone cancer cells Fulltext Access 31 Pages 2017
Physicochemical stability and compatibility testing of levetiracetam in all-in-one parenteral nutrition admixtures in daily practice Fulltext Access 31 Pages 2017
Overcoming Challenges With Intravenous Administration of an Investigational Protein Therapeutic Fulltext Access 31 Pages 2017
3D printed oral solid dosage forms containing hydrochlorothiazide for controlled drug delivery Fulltext Access 31 Pages 2017
Alchemical determination of drug-receptor binding free energy: Where we stand and where we could move to Fulltext Access 31 Pages 2017
Identification of a potential proton donor to the linking oxygen atom in a three-metal ion assisted catalysis pathway catalyzed by Fructose-1, 6-bisphosphatase Fulltext Access 31 Pages 2017
Assessing the binding of cholinesterase inhibitors by docking and molecular dynamics studies Fulltext Access 31 Pages 2017
Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds Fulltext Access 31 Pages 2017
Impact of Mutations on the Higher Order Structure and Activity of a Recombinant Uricase Fulltext Access 31 Pages 2017
Mechanistic and kinetic study on the reaction of methylperoxy radical with atomic iodine Fulltext Access 31 Pages 2017
Development and characterization of magnetic glass-ceramic: Correlation between phosphate and borate matrices and 5-fluorouracil delivery Fulltext Access 31 Pages 2017
Gold nanoshell-based betulinic acid liposomes for synergistic chemo-photothermal therapy Fulltext Access 31 Pages 2017
A novel adamantane thiadiazole derivative induces mitochondria-mediated apoptosis in lung carcinoma cell line Fulltext Access 31 Pages 2017
Next-generation superparamagnetic iron oxide nanoparticles for cancer theranostics Fulltext Access 31 Pages 2017
Effect of alcohol on skin permeation and metabolism of an ester-type prodrug in Yucatan micropig skin Fulltext Access 32 Pages 2017
Palladium-catalysed cross-coupling as a key step in the synthesis of pyridyl-benzamides, -benzylamines and -sulfonamides Fulltext Access 32 Pages 2017
Boredom begets creativity: A solution to the exploitation-exploration trade-off in predictive coding Fulltext Access 32 Pages 2017
The kynurenine pathway and the brain: Challenges, controversies and promises Fulltext Access 32 Pages 2017
The selective cytotoxicity of new triazene compounds to human melanoma cells Fulltext Access 32 Pages 2017
A novel prediction approach for antimalarial activities of Trimethoprim, Pyrimethamine, and Cycloguanil analogues using extremely randomized trees Fulltext Access 32 Pages 2017
Molecular dynamics study of unfolding of lysozyme in water and its mixtures with dimethyl sulfoxide Fulltext Access 32 Pages 2017
New Polyurethane Nail Lacquers for the Delivery of Terbinafine: Formulation and Antifungal Activity Evaluation Fulltext Access 32 Pages 2017
Nanoparticle passage through porcine jejunal mucus: Microfluidics and rheology Fulltext Access 32 Pages 2017
Phototheranostic nanoplatform based on a single cyanine dye for image-guided combinatorial phototherapy Fulltext Access 32 Pages 2017
Assessment of in vivo systemic toxicity and biodistribution of iron-doped silica nanoshells Fulltext Access 32 Pages 2017
Nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging allows precise image-guided tumor-removal surgery Fulltext Access 32 Pages 2017
Synthesis, molecular modeling studies and anticonvulsant activity of certain (1-(benzyl (aryl) amino) cyclohexyl) methyl esters Fulltext Access 32 Pages 2017
Design, synthesis, docking studies and biological evaluation of novel chalcone derivatives as potential histone deacetylase inhibitors Fulltext Access 32 Pages 2017
Cinnamoylated chloroquine analogues: A new structural class of antimalarial agents Fulltext Access 32 Pages 2017
Selective kappa opioid antagonists for treatment of addiction, are we there yet? Fulltext Access 33 Pages 2017
Optimizing Oral Bioavailability in Drug Discovery: An Overview of Design and Testing Strategies and Formulation Options Fulltext Access 33 Pages 2017
The Degradation Chemistry of Farglitazar and Elucidation of the Oxidative Degradation Mechanisms Fulltext Access 33 Pages 2017
Positively charged phthalocyanine-arginine conjugates as efficient photosensitizer for photodynamic therapy Fulltext Access 33 Pages 2017
Evaluation of New Chemical Entities as Substrates of Liver Transporters in the Pharmaceutical Industry: Response to Regulatory Requirements and Future Steps Fulltext Access 33 Pages 2017
The Influence of Mannitol Hemihydrate on the Secondary Drying Dynamics of a Protein Formulation: A Case Study Fulltext Access 33 Pages 2017
Development of Safe and Potent Oil-in-Water Emulsion of Paclitaxel to Treat Peritoneal Dissemination Fulltext Access 33 Pages 2017
Predict protein structural class by incorporating two different modes of evolutionary information into Chou's general pseudo amino acid composition Fulltext Access 33 Pages 2017
Chitosan whisker grafted with oligo(lactic acid) nanoparticles via a green synthesis pathway: Potential as a transdermal drug delivery system Fulltext Access 33 Pages 2017
Molecular topology: A new strategy for antimicrobial resistance control Fulltext Access 33 Pages 2017
The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines Fulltext Access 33 Pages 2017
Allylic isothiouronium salts: The discovery of a novel class of thiourea analogues with antitumor activity Fulltext Access 33 Pages 2017
Efficient click chemistry towards fatty acids containing 1,2,3-triazole: Design and synthesis as potential antifungal drugs for Candida albicans Fulltext Access 33 Pages 2017
A nanoparticle-based nicotine vaccine and the influence of particle size on its immunogenicity and efficacy Fulltext Access 33 Pages 2017
Transformation of arylcarboxamides into 1,3-dioxo-1,3-dihydroisobenzofuran-4-carboxamides Fulltext Access 33 Pages 2017
Factor analysis in optimization of formulation of high content uniformity tablets containing low dose active substance Fulltext Access 33 Pages 2017
Molecular Dynamics as a tool for in silico screening of skin permeability Fulltext Access 33 Pages 2017
A conjugation of stearic acid to apotransferrin, fattigation-platform, as a core to form self-assembled nanoparticles: Encapsulation of a hydrophobic paclitaxel and receptor-driven cancer targeting Fulltext Access 33 Pages 2017
Influence of nitrogen doping in sumanene framework toward hydrogen storage: A computational study Fulltext Access 33 Pages 2017
Modification of polychlorinated phenols and evaluation of their toxicity, biodegradation and bioconcentration using three-dimensional quantitative structure-activity relationship models Fulltext Access 33 Pages 2017
Designing new surfactant peptides for binding to carbon nanotubes via computational approaches Fulltext Access 33 Pages 2017
Electronic properties and gas adsorption behaviour of pristine, silicon-, and boron-doped (8, 0) single-walled carbon nanotube: A first principles study Fulltext Access 33 Pages 2017
Role of glucocorticoid receptor-mediated mechanisms in cocaine memory enhancement Fulltext Access 33 Pages 2017
Anti-connective tissue growth factor detects and reduces plaque inflammation in early-stage carotid atherosclerotic lesions Fulltext Access 34 Pages 2017
Mitochondrial-targeted photosensitizer-loaded folate-albumin nanoparticle for photodynamic therapy of cancer Fulltext Access 34 Pages 2017
Feasibility of Freeze-Drying Oil-in-Water Emulsion Adjuvants and Subunit Proteins to Enable Single-Vial Vaccine Drug Products Fulltext Access 34 Pages 2017
Functional response of novel bioprotective poloxamer-structured vesicles on inflamed skin Fulltext Access 34 Pages 2017
Synthesis, molecular docking studies of coumarinyl-pyrazolinyl substituted thiazoles as non-competitive inhibitors of mushroom tyrosinase Fulltext Access 34 Pages 2017
Triclosan-caffeic acid hybrids: Synthesis, leishmanicidal, trypanocidal and cytotoxic activities Fulltext Access 34 Pages 2017
Noncovalent interaction assisted fullerene for the transportation of some brain anticancer drugs: A theoretical study Fulltext Access 34 Pages 2017
Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22 Fulltext Access 34 Pages 2017
Application of 1-Dimensional and 2-Dimensional Solid-State Nuclear Magnetic Resonance Spectroscopy to the Characterization of Morphine, Morphine Hydrochloride, and Their Hydrates Fulltext Access 34 Pages 2017
Photoactivation provides a mechanistic explanation for pan-assay interference behaviour of 2-aminopyrroles in lipoxygenase inhibition Fulltext Access 34 Pages 2017
Design, synthesis and biological evaluation of novel non-peptide boronic acid derivatives as proteasome inhibitors Fulltext Access 34 Pages 2017
Nose to Brain Delivery of Rivastigmine by In Situ Gelling Cationic Nanostructured Lipid Carriers: Enhanced Brain Distribution and Pharmacodynamics Fulltext Access 34 Pages 2017
Deoxycholic Acid-Conjugated Polyethylenimine for Delivery of Heme Oxygenase-1 Gene in Rat Ischemic Stroke Model Fulltext Access 34 Pages 2017
Aromatase inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and molecular modeling studies of novel phenothiazine derivatives carrying sulfonamide moiety as hybrid molecules Fulltext Access 34 Pages 2017
Effect of cholecystectomy on bile acids as well as relevant enzymes and transporters in mice: Implication for pharmacokinetic changes of rifampicin Fulltext Access 34 Pages 2017
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells Fulltext Access 34 Pages 2017
Effect of storage on the physical stability of thin polymethacrylate-perphenazine films Fulltext Access 34 Pages 2017
Characterization, pharmacokinetics and tissue distribution of chlorogenic acid-loaded self-microemulsifying drug delivery system Fulltext Access 34 Pages 2017
Formulation development and evaluation of Natamycin niosomal in-situ gel for ophthalmic drug delivery Fulltext Access 34 Pages 2017
Design and synthesis of new coumarin hybrids and insight into their mode of antiproliferative action Fulltext Access 34 Pages 2017
Modulation of serotonin transporter function by kappa-opioid receptor ligands Fulltext Access 34 Pages 2017
Nanostructured lipid carriers as oral delivery systems for poorly soluble drugs Fulltext Access 35 Pages 2017
The Effect of Sparkling Water on Intraluminal Formulation Behavior and Systemic Drug Performance Fulltext Access 35 Pages 2017
Cationic branched polymers for cellular delivery of negatively charged cargo Fulltext Access 35 Pages 2017
Application of the melt granulation technique in development of lipid matrix tablets with immediate release of carbamazepine Fulltext Access 35 Pages 2017