Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies Fulltext Access 39 Pages 2017
Recent progress in theranostic applications of hybrid gold nanoparticles Fulltext Access 39 Pages 2017
Design, synthesis and anticancer activity of new monastrol analogues bearing 1,3,4-oxadiazole moiety Fulltext Access 39 Pages 2017
Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues Fulltext Access 39 Pages 2017
Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands Fulltext Access 40 Pages 2017
Discovery of novel diarylpyrazolylquinoline derivatives as potent anti-dengue virus agents Fulltext Access 40 Pages 2017
Synthesis, stability and mechanistic studies of potent anticryptococcal hexapeptides Fulltext Access 40 Pages 2017
Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression Fulltext Access 40 Pages 2017
Effects of Coating Materials and Processing Conditions on Flow Enhancement of Cohesive Acetaminophen Powders by High-Shear Processing With Pharmaceutical Lubricants Fulltext Access 40 Pages 2017
Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity Fulltext Access 40 Pages 2017
How to identify and eliminate compounds with a risk of high clinical dose during the early phase of lead optimisation in drug discovery Fulltext Access 40 Pages 2017
Designing multi-targeted agents: An emerging anticancer drug discovery paradigm Fulltext Access 40 Pages 2017
Design and synthesis of bis(indolyl)ketohydrazide-hydrazones: Identification of potent and selective novel tubulin inhibitors Fulltext Access 40 Pages 2017
Fused heterocycles possessing novel metal-free organic dyes for dye-sensitized solar cells Fulltext Access 40 Pages 2017
Investigation of itraconazole ternary amorphous solid dispersions based on povidone and Carbopol Fulltext Access 40 Pages 2017
Effect of surfactants and drug load on physico-mechanical and dissolution properties of nanocrystalline tadalafil-loaded oral films Fulltext Access 40 Pages 2017
Proinsulin protects against age-related cognitive loss through anti-inflammatory convergent pathways Fulltext Access 40 Pages 2017
Synthesis and evaluation of naphthyl bearing 1,2,3-triazole analogs as antiplasmodial agents, cytotoxicity and docking studies Fulltext Access 40 Pages 2017
Antimalarial activity of novel 4-aminoquinolines active against drug resistant strains Fulltext Access 40 Pages 2017
Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate Fulltext Access 40 Pages 2017
Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy Fulltext Access 40 Pages 2017
Enhancing targeted antibiotic therapy via pH responsive solid lipid nanoparticles from an acid cleavable lipid Fulltext Access 41 Pages 2017
Cell microencapsulation technology: Current vision of its therapeutic potential through the administration routes Fulltext Access 41 Pages 2017
Development, characterization and in vitro evaluation of biodegradable rhein-loaded microparticles for treatment of osteoarthritis Fulltext Access 41 Pages 2017
Self-assembled cationic amphiphiles as antimicrobial peptides mimics: Role of hydrophobicity, linkage type, and assembly state Fulltext Access 41 Pages 2017
Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans Fulltext Access 41 Pages 2017
Effect of plasticizers on the physico-mechanical properties of pullulan based pharmaceutical oral films Fulltext Access 41 Pages 2017
Design, synthesis and evaluation of novel 2-amino-3-(naphth-2-yl)propanoic acid derivatives as potent inhibitors of platelet aggregation Fulltext Access 41 Pages 2017
The cause of multiple sclerosis is autoimmune attack of adenosyltransferase thereby limiting adenosylcobalamin production Fulltext Access 41 Pages 2017
Preformulation studies of ceftriaxone for pediatric non-parenteral administration as an alternative to existing injectable formulations Fulltext Access 41 Pages 2017
Model-based precision dosing of sirolimus in pediatric patients with vascular anomalies Fulltext Access 41 Pages 2017
Development of a Predictive Model for the Long-Term Stability Assessment of Drug-In-Adhesive Transdermal Films Using Polar Pressure-Sensitive Adhesives as Carrier/Matrix Fulltext Access 41 Pages 2017
Synthesis and bioevaluation of 1-phenyl-pyrazole-4-carboxylic acid derivatives as potent xanthine oxidoreductase inhibitors Fulltext Access 41 Pages 2017
Synthesis of novel morpholine conjugated benzophenone analogues and evaluation of antagonistic role against neoplastic development Fulltext Access 41 Pages 2017
In silico designing of therapeutic protein enriched with branched-chain amino acids for the dietary treatment of chronic liver disease Fulltext Access 42 Pages 2017
Analysis of polymorphic contamination in meloxicam raw materials and its effects on the physicochemical quality of drug product Fulltext Access 42 Pages 2017
Sustained release of intravitreal flurbiprofen from a novel drug-in-liposome-in-hydrogel formulation Fulltext Access 42 Pages 2017
Medicines for Pediatric Patients-Biopharmaceutical, Developmental, and Regulatory Considerations Fulltext Access 42 Pages 2017
An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors Fulltext Access 42 Pages 2017
Diphenylurea derivatives for combating methicillin- and vancomycin-resistant Staphylococcus aureus Fulltext Access 42 Pages 2017
Lethal effects of an insecticidal spider venom peptide involve positive allosteric modulation of insect nicotinic acetylcholine receptors Fulltext Access 42 Pages 2017
Recent developments in small molecule therapies for renal cell carcinoma Fulltext Access 42 Pages 2017
Molecular epigenetic targets for liver diseases: current challenges and future prospects Fulltext Access 42 Pages 2017
Design, synthesis, and biological evaluation of optimized phthalazine derivatives as hedgehog signaling pathway inhibitors Fulltext Access 42 Pages 2017
The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers Fulltext Access 42 Pages 2017
Synthesis and biological evaluation of salinomycin triazole analogues as anticancer agents Fulltext Access 42 Pages 2017
Rat animal models for screening medications to treat alcohol use disorders Fulltext Access 43 Pages 2017
Effects of synergistic and non-synergistic anions on the iron binding site from serum transferrin: A molecular dynamic simulation analysis Fulltext Access 43 Pages 2017
Conformational and energy evaluations of novel peptides binding to dengue virus envelope protein Fulltext Access 43 Pages 2017
Involvement of Proton-Coupled Organic Cation Antiporter in Varenicline Transport at Blood-Brain Barrier of Rats and in Human Brain Capillary Endothelial Cells Fulltext Access 43 Pages 2017
Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms Fulltext Access 43 Pages 2017
The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders Fulltext Access 43 Pages 2017
Low-Molecular-Weight Heparin-Coated and Montelukast-Filled Inhalable Particles: A Dual-Drug Delivery System for Combination Therapy in Asthma Fulltext Access 43 Pages 2017
Electrospun polymeric micro/nanofibrous scaffolds for long-term drug release and their biomedical applications Fulltext Access 43 Pages 2017
Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors Fulltext Access 44 Pages 2017
Monitoring of the energy levels by heteroatom substitution to hexacene and controlling over singlet fission and photo-oxidative resistance Fulltext Access 44 Pages 2017
Topological and quantum molecular descriptors as effective tools for analyzing cytotoxic activity achieved by a series of (diselanediyldibenzene-4,1-diylnide)biscarbamate derivatives Fulltext Access 44 Pages 2017
Improving blend content uniformity via dry particle coating of micronized drug powders Fulltext Access 44 Pages 2017
A Formulation Development Approach to Identify and Select Stable Ultra-High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities Fulltext Access 44 Pages 2017
Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease Fulltext Access 44 Pages 2017
Simvastatin-loaded nanostructured lipid carriers attenuate the atherogenic risk of erythrocytes in hyperlipidemic rats Fulltext Access 44 Pages 2017
Effect of Grinding on the Solid-State Stability and Particle Dissolution of Acyclovir Polymorphs Fulltext Access 44 Pages 2017
Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer Fulltext Access 44 Pages 2017
Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide Fulltext Access 45 Pages 2017
Symmetry in normal modes and its strong dependence on symmetry in structure Fulltext Access 45 Pages 2017
Sampling conformational space of intrinsically disordered proteins in explicit solvent: Comparison between well-tempered ensemble approach and solute tempering method Fulltext Access 45 Pages 2017
Auspicious role of the steroidal heterocyclic derivatives as a platform for anti-cancer drugs Fulltext Access 45 Pages 2017
Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold Fulltext Access 45 Pages 2017
Graphene- gold based nanocomposites applications in cancer diseases; Efficient detection and therapeutic tools Fulltext Access 45 Pages 2017
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease Fulltext Access 45 Pages 2017
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase Fulltext Access 45 Pages 2017
Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis Fulltext Access 45 Pages 2017
Exploration of flexible phenylpropylurea scaffold as novel cardiac myosin activators for the treatment of systolic heart failure Fulltext Access 45 Pages 2017
Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data Fulltext Access 45 Pages 2017
Towards the antioxidant therapy in Osteoarthritis: Contribution of nanotechnology Fulltext Access 46 Pages 2017
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects Fulltext Access 46 Pages 2017
Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy Fulltext Access 46 Pages 2017
Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics Fulltext Access 46 Pages 2017
Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases Fulltext Access 46 Pages 2017
Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators Fulltext Access 46 Pages 2017
The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model Fulltext Access 46 Pages 2017
Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives Fulltext Access 46 Pages 2017
Pulmonary delivery of synergistic combination of fluoroquinolone antibiotic complemented with proteolytic enzyme: A novel antimicrobial and antibiofilm strategy Fulltext Access 46 Pages 2017
Protein secondary structure prediction: A survey of the state of the art Fulltext Access 46 Pages 2017