Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits Fulltext Access 47 Pages 2017
Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures Fulltext Access 47 Pages 2017
Extracellular vesicles in food: Experimental evidence of their secretion in grape fruits Fulltext Access 47 Pages 2017
Pharmaceutical counselling about different types of tablet-splitting methods based on the results of weighing tests and mechanical development of splitting devices Fulltext Access 47 Pages 2017
Design, selective alkylation and X-ray crystal structure determination of dihydro-indolyl-1,2,4-triazole-3-thione and its 3-benzylsulfanyl analogue as potent anticancer agents Fulltext Access 47 Pages 2017
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea Fulltext Access 47 Pages 2017
Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy Fulltext Access 47 Pages 2017
Novel flavonolignan hybrid antioxidants: From enzymatic preparation to molecular rationalization Fulltext Access 47 Pages 2017
Influence of substituent heteroatoms on the cytoprotective properties of pyrimidinol antioxidants Fulltext Access 47 Pages 2017
Separation based adsorption of ethanol-water mixture in azeotropic solution by single-walled carbon, boron-nitride and silicon-carbide nanotubes Fulltext Access 48 Pages 2017
Synthesis and biological evaluation of new substituted thioglycolurils, their analogues and derivatives Fulltext Access 48 Pages 2017
Recent Progress in Hepatocyte Culture Models and Their Application to the Assessment of Drug Metabolism, Transport, and Toxicity in Drug Discovery: The Value of Tissue Engineering for the Successful Development of a Microphysiological System Fulltext Access 48 Pages 2017
Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity Fulltext Access 49 Pages 2017
New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation Fulltext Access 49 Pages 2017
Discovery of novel polycyclic spiro-fused carbocyclicoxindole-based anticancer agents Fulltext Access 49 Pages 2017
Formulation and characterization of mucoadhesive controlled release matrix tablets of captopril Fulltext Access 49 Pages 2017
Macrophage-Mediated Clofazimine Sequestration Is Accompanied by a Shift in Host Energy Metabolism Fulltext Access 49 Pages 2017
Tribenzyltin carboxylates as anticancer drug candidates: Effect on the cytotoxicity, motility and invasiveness of breast cancer cell lines Fulltext Access 50 Pages 2017
Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids Fulltext Access 50 Pages 2017
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease Fulltext Access 50 Pages 2017
Synthesis of novel benzylidene analogues of betulinic acid as potent cytotoxic agents Fulltext Access 50 Pages 2017
Recent progresses in biomedical applications of aptamer-functionalized systems Fulltext Access 50 Pages 2017
Sensitivity Analysis and Uncertainty Quantification in Pulmonary Drug Delivery of Orally Inhaled Pharmaceuticals Fulltext Access 50 Pages 2017
Synthesis and biological evaluation of 4 arylcoumarin analogues as tubulin-targeting antitumor agents Fulltext Access 51 Pages 2017
Very fast dissolving acid carboxymethylcellulose-rifampicin matrix: Development and solid-state characterization Fulltext Access 51 Pages 2017
Structures and biochemical evaluation of silver(I) 5,5-diethylbarbiturate complexes with bis(diphenylphosphino)alkanes as potential antimicrobial and anticancer agents Fulltext Access 51 Pages 2017
Discovery of novel 3-(hydroxyalkoxy)-2-alkylchromen-4-one analogs as interleukin-5 inhibitors Fulltext Access 51 Pages 2017
Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands Fulltext Access 52 Pages 2017
Prediction of Losartan-Active Carboxylic Acid Metabolite Exposure Following Losartan Administration Using Static and Physiologically Based Pharmacokinetic Models Fulltext Access 52 Pages 2017
Design and synthesis of indoline thiohydantoin derivatives based on enzalutamide as antiproliferative agents against prostate cancer Fulltext Access 52 Pages 2017
Control Strategies for Drug Product Continuous Direct Compression-State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materials and Commercial Products Fulltext Access 52 Pages 2017
Design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs Fulltext Access 53 Pages 2017
Application of X-Ray Sensors for In-line and Noninvasive Monitoring of Mass Flow Rate in Continuous Tablet Manufacturing Fulltext Access 53 Pages 2017
Analysis of the Change in the Blood Concentration-Time Profile Caused by Complex Drug-Drug Interactions in the Liver Considering the Enterohepatic Circulation: Examining Whether the Inhibition Constants for Uptake, Metabolism, and Biliary Excretion Can be Fulltext Access 54 Pages 2017
Rational design, synthesis and biological screening of triazine-triazolopyrimidine hybrids as multitarget anti-Alzheimer agents Fulltext Access 54 Pages 2017
Enhanced in vitro cytotoxicity and anti-tumor activity of vorinostat-loaded pluronic micelles with prolonged release and reduced hepatic and renal toxicities Fulltext Access 54 Pages 2017
Estrogen receptor agonists/antagonists in breast cancer therapy: A critical review Fulltext Access 54 Pages 2017
Synthesis of 1,2,3-triazole hydrazide derivatives exhibiting anti-phytopathogenic activity Fulltext Access 54 Pages 2017
Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs Fulltext Access 54 Pages 2017
Comparative anti-psoriatic efficacy studies of clobetasol loaded chitin nanogel and marketed cream Fulltext Access 54 Pages 2017
Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs Fulltext Access 54 Pages 2017
A tumor-targeted activatable phthalocyanine-tetrapeptide-doxorubicin conjugate for synergistic chemo-photodynamic therapy Fulltext Access 55 Pages 2017
Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real? Fulltext Access 55 Pages 2017
Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance Fulltext Access 56 Pages 2017
Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease Fulltext Access 56 Pages 2017
New Approach and Practical Modelling of Bead Milling Process for the Manufacturing of Nanocrystalline Suspensions Fulltext Access 56 Pages 2017
Applications of sharpless asymmetric dihydroxylation in the total synthesis of natural products Fulltext Access 57 Pages 2017
Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective Fulltext Access 57 Pages 2017
Real-Time Visualization of the Precipitation and Phase Behavior of Octaethylporphyrin in Lipid Microparticles Fulltext Access 57 Pages 2017
Studying the influence of formulation and process variables on Vancomycin-loaded polymeric nanoparticles as potential carrier for enhanced ophthalmic delivery Fulltext Access 58 Pages 2017
Design, synthesis, biological evaluation and molecular modeling study of novel macrocyclic bisbibenzyl analogues as antitubulin agents Fulltext Access 58 Pages 2017
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation Fulltext Access 59 Pages 2017
Recent development of synthetic nonviral systems for sustained gene delivery Fulltext Access 59 Pages 2017
Friability Testing as a New Stress-Stability Assay for Biopharmaceuticals Fulltext Access 60 Pages 2017
New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking Fulltext Access 60 Pages 2017
Design, synthesis and antimicrobial evaluation of novel benzimidazole-incorporated sulfonamide analogues Fulltext Access 60 Pages 2017
Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors Fulltext Access 60 Pages 2017
Synthesis and antioxidant evaluation of desmethylxanthohumol analogs and their dimers Fulltext Access 61 Pages 2017
Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents Fulltext Access 61 Pages 2017
Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia Fulltext Access 61 Pages 2017
A Schmidt rearrangement-mediated synthesis of novel tetrahydro-benzo[1,4]diazepin-5-ones as potential anticancer and antiprotozoal agents Fulltext Access 62 Pages 2017
Pyrazole derived ultra-short antimicrobial peptidomimetics with potent anti-biofilm activity Fulltext Access 63 Pages 2017
A molecular docking study of the interactions between human transferrin and seven metallocene dichlorides Fulltext Access 65 Pages 2017
Norepinephrine alkaloids as antiplasmodial agents: Synthesis of syncarpamide and insight into the structure-activity relationships of its analogues as antiplasmodial agents Fulltext Access 66 Pages 2017
Polo-like kinase 2 phosphorylation of amyloid precursor protein regulates activity-dependent amyloidogenic processing Fulltext Access 66 Pages 2017
An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors Fulltext Access 66 Pages 2017
Synthetic approaches to radiochemical probes for imaging of bacterial infections Fulltext Access 68 Pages 2017
Unravelling cortico-hypothalamic pathways regulating unconditioned fear-induced antinociception and defensive behaviours Fulltext Access 68 Pages 2017
The synthesis and evaluation of triazolopyrimidines as anti-tubercular agents Fulltext Access 69 Pages 2017
Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis Fulltext Access 69 Pages 2017
Metabotropic glutamate receptors as therapeutic targets in Parkinson's disease: An update from the last 5 years of research Fulltext Access 70 Pages 2017
Synthesis of novel quinoline-based 4,5-dihydro-1H-pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents Fulltext Access 73 Pages 2017
Fructose-1,6-bisphosphatase inhibitors: A new valid approach for management of type 2 diabetes mellitus Fulltext Access 74 Pages 2017
The dynamic gastric environment and its impact on drug and formulation behaviour Fulltext Access 84 Pages 2017
Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes Fulltext Access 84 Pages 2017
Novel multi-substituted benzyl acridone derivatives as survivin inhibitors for hepatocellular carcinoma treatment Fulltext Access 108 Pages 2017
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds Fulltext Access 119 Pages 2017
Synthesis of natural products containing fully functionalized cyclopentanes Fulltext Access 120 Pages 2017
Current applications of organocatalysts in asymmetric aldol reactions: An update Fulltext Access 121 Pages 2017
Therapeutic evolution of benzimidazole derivatives in the last quinquennial period Fulltext Access 129 Pages 2017