New techniques of on-line biological sample processing and their application in the field of biopharmaceutical analysis Fulltext Access 12 Pages 2016
Design, synthesis and biological evaluation of novel hydroxamic acids bearing artemisinin skeleton Fulltext Access 12 Pages 2016
Differential modulation of the discriminative stimulus effects of methamphetamine and cocaine by alprazolam and oxazepam in male and female rats Fulltext Access 12 Pages 2016
Behavioral, neurochemical and molecular changes after acute deep brain stimulation of the infralimbic prefrontal cortex Fulltext Access 12 Pages 2016
Toward isolating the role of dopamine in the acquisition of incentive salience attribution Fulltext Access 12 Pages 2016
Impact of the digital revolution on the future of pharmaceutical formulation science Fulltext Access 12 Pages 2016
Non-invasive intranasal delivery of quetiapine fumarate loaded microemulsion for brain targeting: Formulation, physicochemical and pharmacokinetic consideration Fulltext Access 12 Pages 2016
Animal assisted intervention: A systematic review of benefits and risks Fulltext Access 12 Pages 2016
Drug discovery strategies to outer membrane targets in Gram-negative pathogens Fulltext Access 12 Pages 2016
Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice Fulltext Access 12 Pages 2016
Microwave-promoted, catalyst-free, multi-component reaction of proline, aldehyde, 1,3-diketone: one pot synthesis of pyrrolizidines and pyrrolizinones Fulltext Access 12 Pages 2016
Synthesis of fluorinated building blocks based on spiro[3.3]heptane scaffold Fulltext Access 12 Pages 2016
Formation and reductive ring opening reactions of indolyl-isoxazolidines: access to novel natural product analogs and precursors Fulltext Access 12 Pages 2016
An expedient strategy for the diversity-oriented synthesis of macrocyclic compounds with natural product-like characteristics Fulltext Access 12 Pages 2016
Synthesis and evaluation of 9-substituted anthracenes with potential in reversible polymer systems Fulltext Access 12 Pages 2016
Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors reverse ketamine-induced schizophrenia-like deficits in rats Fulltext Access 12 Pages 2016
Somatostatin receptor subtype 4 activation is involved in anxiety and depression-like behavior in mouse models Fulltext Access 12 Pages 2016
Silicone Migration From Baked-on Silicone Layers. Particle Characterization in Placebo and Protein Solutions Fulltext Access 12 Pages 2016
Additive effects on the improvement of insecticidal activity: Design, synthesis, and insecticidal activity of novel pymetrozine derivatives Fulltext Access 12 Pages 2016
Design, synthesis, structure-activity relationships, and docking studies of pyrazole-containing derivatives as a novel series of potent glucagon receptor antagonists Fulltext Access 12 Pages 2016
Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents Fulltext Access 12 Pages 2016
Enrichment of immunoregulatory proteins in the biomolecular corona of nanoparticles within human respiratory tract lining fluid Fulltext Access 12 Pages 2016
Comparison of complement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable immune toxicity model Fulltext Access 12 Pages 2016
Protection against respiratory syncytial virus by inactivated influenza virus carrying a fusion protein neutralizing epitope in a chimeric hemagglutinin Fulltext Access 12 Pages 2016
Evaluation of Three Amorphous Drug Delivery Technologies to Improve the Oral Absorption of Flubendazole Fulltext Access 12 Pages 2016
Physiologically Based Absorption Modeling to Impact Biopharmaceutics and Formulation Strategies in Drug Development-Industry Case Studies Fulltext Access 12 Pages 2016
Brain-Targeting Chemical Delivery Systems and Their Cyclodextrin-Based Formulations in Light of the Contributions of Marcus E. Brewster Fulltext Access 12 Pages 2016
The Slow Relaxation Dynamics in the Amorphous Pharmaceutical Drugs Cimetidine, Nizatidine, and Famotidine Fulltext Access 12 Pages 2016
Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography Fulltext Access 12 Pages 2016
Recent advances in the discovery of heparanase inhibitors as anti-cancer agents Fulltext Access 12 Pages 2016
Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity Fulltext Access 12 Pages 2016
Enhancing backbone sampling in Monte Carlo simulations using internal coordinates normal mode analysis Fulltext Access 12 Pages 2016
In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification Fulltext Access 12 Pages 2016
Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the 'reversed' amide scaffold Fulltext Access 12 Pages 2016
The synthesis and biological evaluation of alkyl and benzyl naphthyridinium analogs of eupolauridine as potential antimicrobial and cytotoxic agents Fulltext Access 12 Pages 2016
Multiple Integrated Complementary Healing Approaches: Energetics & Light for bone Fulltext Access 12 Pages 2016
Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi Fulltext Access 12 Pages 2016
Facile preparation of acrylamide grafted locust bean gum-poly(vinyl alcohol) interpenetrating polymer network microspheres for controlled oral drug delivery Fulltext Access 12 Pages 2016
Antitumor activity of transferrin-modified- artemether lipid nanospheres in cancer cell lines Fulltext Access 12 Pages 2016
Investigation of free amino acid, total phenolics, antioxidant activity and purine alkaloids to assess the health properties of non-Camellia tea Fulltext Access 12 Pages 2016
Spectrophotometric determination of the sulfhydryl containing drug mesna Fulltext Access 12 Pages 2016
Tailored-interpenetrating polymer network beads of κ-carrageenan and sodium carboxymethyl cellulose for controlled drug delivery Fulltext Access 12 Pages 2016
Atorvastatin–cyclodextrin systems: Physiochemical and biopharmaceutical evaluation Fulltext Access 12 Pages 2016
A microstructural study of water effects in lipid-based pharmaceutical formulations for liquid filling of capsules Fulltext Access 12 Pages 2016
Toward overcoming cisplatin resistance via sterically hindered platinum(II) complexes Fulltext Access 12 Pages 2016
From macro to nano polysaccharide hydrogels: An opportunity for the delivery of drugs Fulltext Access 12 Pages 2016
Three-dimensional podocyte–endothelial cell co-cultures: Assembly, validation, and application to drug testing and intercellular signaling studies Fulltext Access 12 Pages 2016
Novel chewable colon targeted tablets of bumadizone calcium for treatment of ulcerative colitis: Formulation and optimization Fulltext Access 12 Pages 2016
Development of mucoadhesive and thermosensitive eyedrops to improve the ophthalmic bioavailability of ibuprofen Fulltext Access 12 Pages 2016
Pickering emulsions based on cyclodextrins: A smart solution for antifungal azole derivatives topical delivery Fulltext Access 12 Pages 2016
Screening of new antileukemic agents from essential oils of algae extracts and computational modeling of their interactions with intracellular signaling nodes Fulltext Access 12 Pages 2016
The potential of immobilized artificial membrane chromatography to predict human oral absorption Fulltext Access 12 Pages 2016
Bioavailability enhancement of atovaquone using hot melt extrusion technology Fulltext Access 12 Pages 2016
Evaluation of the Intestinal Colonizing Potential and Immunomodulating Capacity of Lactobacilli Microspheres Fulltext Access 12 Pages 2016
Investigating the role of mucin in the delivery of nanoparticles to cellular models of human cancer disease: an in vitro study Fulltext Access 12 Pages 2016
Dihydropyrimidine based hydrazine dihydrochloride derivatives as potent urease inhibitors Fulltext Access 12 Pages 2016
Emerging targets and new small molecule therapies in Parkinson’s disease treatment Fulltext Access 12 Pages 2016
Tailored Antibiotic Combination Powders for Inhaled Rotational Antibiotic Therapy Fulltext Access 12 Pages 2016
Design, synthesis and biological evaluation of novel donepezil–coumarin hybrids as multi-target agents for the treatment of Alzheimer’s disease Fulltext Access 12 Pages 2016
Design, synthesis of phenstatin/isocombretastatin-oxindole conjugates as antimitotic agents Fulltext Access 12 Pages 2016
Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity Fulltext Access 12 Pages 2016
Synthesis and biological evaluation of a series of non-hemiacetal ester derivatives of artemisinin Fulltext Access 12 Pages 2016
Discovery of novel sesquistilbene indanone analogues as potent anti-inflammatory agents Fulltext Access 12 Pages 2016
Reversible Opening of Intercellular Junctions of Intestinal Epithelial and Brain Endothelial Cells With Tight Junction Modulator Peptides Fulltext Access 12 Pages 2016
Addition of Monovalent Electrolytes to Improve Storage Stability of Freeze-Dried Protein Formulations Fulltext Access 12 Pages 2016
Design, synthesis and Structure–activity relationship studies of new thiazole-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes Fulltext Access 12 Pages 2016
Structure–activity relationship study of anticancer thymidine–quinoxaline conjugates under the low radiance of long wavelength ultraviolet light for photodynamic therapy Fulltext Access 12 Pages 2016
Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation Fulltext Access 13 Pages 2016
Global and Targeted Proteomics of Prostate Cancer Cell Secretome: Combination of 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry and In Silico Selection Selected Reaction Monitoring Analysis Fulltext Access 13 Pages 2016
Determination of the Degradation Chemistry of the Antitumor Agent Pemetrexed Disodium Fulltext Access 13 Pages 2016
High fat diet augments amphetamine sensitization in mice: Role of feeding pattern, obesity, and dopamine terminal changes Fulltext Access 13 Pages 2016
Design of an In Situ Cross-Linked Eutectic Tablet for Enhanced Delivery of Gastro-Sensitive Proteins and Peptides Fulltext Access 13 Pages 2016
Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects Fulltext Access 13 Pages 2016
Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice Fulltext Access 13 Pages 2016
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats Fulltext Access 13 Pages 2016
Induction of apoptosis in human leukemia cells through an intrinsic pathway by cathachunine, a unique alkaloid isolated from Catharanthus roseus Fulltext Access 13 Pages 2016
Enhanced autophagic activity of artocarpin in human hepatocellular carcinoma cells through improving its solubility by a nanoparticle system Fulltext Access 13 Pages 2016
Current Inhalers Deliver Very Small Doses to the Lower Tracheobronchial Airways: Assessment of Healthy and Constricted Lungs Fulltext Access 13 Pages 2016
The Hydrolysis of Diclofenac Esters: Synthetic Prodrug Building Blocks for Biodegradable Drug-Polymer Conjugates Fulltext Access 13 Pages 2016
Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis Fulltext Access 13 Pages 2016
Alpha-linolenic acid given as enteral or parenteral nutritional intervention against sensorimotor and cognitive deficits in a mouse model of ischemic stroke Fulltext Access 13 Pages 2016
Using Texture Analysis Technique to Assess the Freeze-Dried Cakes in Vials Fulltext Access 13 Pages 2016
A novel systems pharmacology platform to dissect action mechanisms of traditional Chinese medicines for bovine viral diarrhea disease Fulltext Access 13 Pages 2016
Towards patient stratification and treatment in the autoimmune disease lupus erythematosus using a systems pharmacology approach Fulltext Access 13 Pages 2016
Novel minimal physiologically-based model for the prediction of passive tubular reabsorption and renal excretion clearance Fulltext Access 13 Pages 2016
Dissolution and coarsening of polydisperse, polymorph drug particles liberated from a disintegrating finished dosage form: Theoretical considerations Fulltext Access 13 Pages 2016
Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions Fulltext Access 13 Pages 2016
Comparison of metoprolol tartrate multiple-unit lipid matrix systems produced by different technologies Fulltext Access 13 Pages 2016
A focus on mucoadhesive polymers and their application in buccal dosage forms Fulltext Access 13 Pages 2016