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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Acupuncture for shoulder pain after stroke: A randomized controlled clinical trial
Fulltext Access 11 Pages 2016
Reversal of social deficits by subchronic oxytocin in two autism mouse models
Fulltext Access 11 Pages 2016
Transdermal film-loaded finasteride microplates to enhance drug skin permeation: Two-step optimization study
Fulltext Access 11 Pages 2016
Co-crystal formation based on structural matching
Fulltext Access 11 Pages 2016
Quantitative structure-retention relationships of flavonoids unraveled by immobilized artificial membrane chromatography
Fulltext Access 11 Pages 2016
Formulation of hydrogel-thickened nonionic microemulsions with enhanced percutaneous delivery of ibuprofen assessed in vivo in rats
Fulltext Access 11 Pages 2016
Enzyme-responsive destabilization of stabilized plasmid-lipid nanoparticles as an efficient gene delivery
Fulltext Access 11 Pages 2016
Doxycycline hyclate-loaded bleached shellac in situ forming microparticle for intraperiodontal pocket local delivery
Fulltext Access 11 Pages 2016
Tailoring the mucoadhesive and sustained release characteristics of mesalamine loaded formulations for local treatment of distal forms of ulcerative colitis
Fulltext Access 11 Pages 2016
Nanostructured lipid carriers as robust systems for topical lidocaine-prilocaine release in dentistry
Fulltext Access 11 Pages 2016
Inhibitory effect of quercetin on colorectal lung metastasis through inducing apoptosis, and suppression of metastatic ability
Fulltext Access 11 Pages 2016
Effects of low molecular weight procyanidin rich extract from french maritime pine bark on cardiovascular disease risk factors in stage-1 hypertensive subjects: Randomized, double-blind, crossover, placebo-controlled intervention trial
Fulltext Access 11 Pages 2016
Invited reviewHistamine and the striatum
Fulltext Access 11 Pages 2016
REVIEWRenal drug transporters and their significance in drug-drug interactions
Fulltext Access 11 Pages 2016
Multi-objective shadow prices point at principles of metabolic regulation
Fulltext Access 11 Pages 2016
Adaptive moment closure for parameter inference of biochemical reaction networks
Fulltext Access 11 Pages 2016
A neural mechanism of dynamic gating of task-relevant information by top-down influence in primary visual cortex
Fulltext Access 11 Pages 2016
Non-standard amino acids and peptides: From self-assembly to nanomaterials
Fulltext Access 11 Pages 2016
Designing a next generation of proton sponges: cyclopropeniminophosphazenes as the strongest pincer ligands
Fulltext Access 11 Pages 2016
Transition metal-free formal [2+2+2] cycloaddition reactions of alkynes
Fulltext Access 11 Pages 2016
Codon bias from minimization of codon–anticodon interaction
Fulltext Access 11 Pages 2016
Efficient synthesis of functionalized chromones via a two-base mediated formal [3+3] cycloaddition
Fulltext Access 11 Pages 2016
Short and efficient synthesis of 1-(2-oxido-1,2,5-oxadiazol-3-yl)alkyl nitrates by unconventional nitrooxylation of 3-alkyl-1,2,5-oxadiazole 2-oxides
Fulltext Access 11 Pages 2016
Host-Guest Complexes of Carboxylated Pillar[n]arenes With Drugs
Fulltext Access 11 Pages 2016
The inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach
Fulltext Access 11 Pages 2016
Why and how have drug discovery strategies in pharma changed? What are the new mindsets?
Fulltext Access 11 Pages 2016
Are epigenetic drugs for diabetes and obesity at our door step?
Fulltext Access 11 Pages 2016
Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity
Fulltext Access 11 Pages 2016
Going with the flow: harnessing the power of the vasculature for targeted therapy in rheumatoid arthritis
Fulltext Access 11 Pages 2016
“Back to the Future”: A New Look at Hydroxypropyl Beta-Cyclodextrins
Fulltext Access 11 Pages 2016
Cholesterol-Targeted Anticancer and Apoptotic Effects of Anionic and Polycationic Amphiphilic Cyclodextrin Nanoparticles
Fulltext Access 11 Pages 2016
Review of Disintegrants and the Disintegration Phenomena
Fulltext Access 11 Pages 2016
Accelerating Vaccine Formulation Development Using Design of Experiment Stability Studies
Fulltext Access 11 Pages 2016
Stability and Ocular Pharmacokinetics of Celecoxib-Loaded Nanoparticles Topical Ophthalmic Formulations
Fulltext Access 11 Pages 2016
A one-pot synthesis of trichloromethylated pyrimidines from trichloroacetimidamides and acetylenic esters
Fulltext Access 11 Pages 2016
Freeze-Drying Process Development and Scale-Up: Scale-Up of Edge Vial Versus Center Vial Heat Transfer Coefficients, Kv
Fulltext Access 11 Pages 2016
On the Design of a Fuzzy Logic-Based Control System for Freeze-Drying Processes
Fulltext Access 11 Pages 2016
Both Reversible Self-Association and Structural Changes Underpin Molecular Viscoelasticity of mAb Solutions
Fulltext Access 11 Pages 2016
Graphical abstract contents listing
Fulltext Access 11 Pages 2016
Synthesis, characterization and antimicrobial evaluation of some novel quinoline derivatives bearing different heterocyclic moieties
Fulltext Access 11 Pages 2016
Profile comparison revealed deviation from structural constraint at the positively selected sites
Fulltext Access 11 Pages 2016
Purinergic mechanisms in neuroinflammation: An update from molecules to behavior
Fulltext Access 11 Pages 2016
Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents
Fulltext Access 11 Pages 2016
Unraveling a new circuitry for sleep regulation in Parkinson's disease
Fulltext Access 11 Pages 2016
Neuronal histamine and cognitive symptoms in Alzheimer's disease
Fulltext Access 11 Pages 2016
Optimization of solid-self nanoemulsifying drug delivery system for solubility and release profile of clonazepam using simplex lattice design
Fulltext Access 11 Pages 2016
Relating Protein-Protein Interactions and Aggregation Rates From Low to High Concentrations
Fulltext Access 11 Pages 2016
Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin
Fulltext Access 11 Pages 2016
Rational Design and Characterization of a Nanosuspension for Intraoral Administration Considering Physiological Conditions
Fulltext Access 11 Pages 2016
Preparation and Characterization of Amylose Inclusion Complexes for Drug Delivery Applications
Fulltext Access 11 Pages 2016
Thermosensitive Hydrogel System With Paclitaxel Liposomes Used in Localized Drug Delivery System for In Situ Treatment of Tumor: Better Antitumor Efficacy and Lower Toxicity
Fulltext Access 11 Pages 2016
Colloidal Instability Fosters Agglomeration of Subvisible Particles Created by Rupture of Gels of a Monoclonal Antibody Formed at Silicone Oil-Water Interfaces
Fulltext Access 11 Pages 2016
Clearance Prediction of HIV Protease Inhibitors in Man: Role of Hepatic Uptake
Fulltext Access 11 Pages 2016
Preclinical Evaluation of an Epidermal Growth Factor Receptor-Targeted Doxorubicin-Peptide Conjugate: Toxicity, Biodistribution, and Efficacy in Mice
Fulltext Access 11 Pages 2016
Toward Carbon Monoxide-Based Therapeutics: Critical Drug Delivery and Developability Issues
Fulltext Access 11 Pages 2016
Factors Governing the Accuracy of Subvisible Particle Counting Methods
Fulltext Access 11 Pages 2016
Preparation and Physical Characterization of a Diclofenac-Ranitidine Co-precipitate for Improving the Dissolution of Diclofenac
Fulltext Access 11 Pages 2016
Folic acid loaded lipid nanocarriers with promoted skin antiaging and antioxidant efficacy
Fulltext Access 11 Pages 2016
Quantification of caffeine and loperamide in printed formulations by infrared spectroscopy
Fulltext Access 11 Pages 2016
Dendrimers and their supramolecular nanostructures for biomedical applications
Fulltext Access 11 Pages 2016
Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review
Fulltext Access 11 Pages 2016
Stability testing of drug eluting stents
Fulltext Access 11 Pages 2016
Characterization and evaluation of a folic acid receptor-targeted cyclodextrin complex as an anticancer drug delivery system
Fulltext Access 11 Pages 2016
Evaluation of photodynamic activity, photostability and in vitro drug release of zinc phthalocyanine-loaded nanocapsules
Fulltext Access 11 Pages 2016
Cell based assays for anti-Plasmodium activity evaluation
Fulltext Access 11 Pages 2016
Estimating the variability in fraction absorbed as a paradigm for informing formulation development in early clinical drug development
Fulltext Access 11 Pages 2016
Systematic Evaluation of Wajima Superposition (Steady-State Concentration to Mean Residence Time) in the Estimation of Human Intravenous Pharmacokinetic Profile
Fulltext Access 11 Pages 2016
Bimetallic chiral nanoparticles as catalysts for asymmetric synthesis
Fulltext Access 11 Pages 2016
A new approach to the automatic identification of organism evolution using neural networks
Fulltext Access 11 Pages 2016
The system-resonance approach in modeling genetic structures
Fulltext Access 11 Pages 2016
Secondary pharmacology: screening and interpretation of off-target activities – focus on translation
Fulltext Access 11 Pages 2016
Non-human tools for the evaluation of bitter taste in the design and development of medicines: a systematic review
Fulltext Access 11 Pages 2016
Protective effects of lupeol against mancozeb-induced genotoxicity in cultured human lymphocytes
Fulltext Access 11 Pages 2016
Comparative evaluation of 4 and 6-carbon spacer conformationally flexible tetrahydroisoquinolinyl benzamide analogues for imaging the sigma-2 receptor status of solid tumors
Fulltext Access 11 Pages 2016
Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials
Fulltext Access 11 Pages 2016
Influence of physical properties of carrier on the performance of dry powder inhalers
Fulltext Access 11 Pages 2016
The effect of ethyl acetate extract from persimmon leaves on Alzheimer's disease and its underlying mechanism
Fulltext Access 11 Pages 2016
Targeted metabolomic profiling of cardioprotective effect of Ginkgo biloba L. extract on myocardial ischemia in rats
Fulltext Access 11 Pages 2016
Analysis of large-scale tablet coating: Modeling, simulation and experiments
Fulltext Access 11 Pages 2016
Protective effects of isolecanoric acid on neurodegenerative in vitro models
Fulltext Access 11 Pages 2016
Cancer chemoresistance; biochemical and molecular aspects: a brief overview
Fulltext Access 11 Pages 2016
Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety
Fulltext Access 11 Pages 2016
Compound high-quality criteria: a new vision to guide the development of drugs, current situation
Fulltext Access 12 Pages 2016
Characterisation and surface-profiling techniques for composite particles produced by dry powder coating in pharmaceutical drug delivery
Fulltext Access 12 Pages 2016
The potential of computed crystal energy landscapes to aid solid-form development
Fulltext Access 12 Pages 2016
Quantum cognition based on an ambiguous representation derived from a rough set approximation
Fulltext Access 12 Pages 2016
Reaction screening in continuous flow reactors
Fulltext Access 12 Pages 2016
Characterization and classification of adherent cells in monolayer culture using automated tracking and evolutionary algorithms
Fulltext Access 12 Pages 2016
Predicting changes of reaction networks with partial kinetic information
Fulltext Access 12 Pages 2016
The role of crossover operator in evolutionary-based approach to the problem of genetic code optimization
Fulltext Access 12 Pages 2016
Synthesis and electron-donating properties of novel norphthalocyanines containing thiacrown ether-linked tetrathiafulvalene moieties
Fulltext Access 12 Pages 2016
Highly efficient synthesis of tetrasubstituted 2,3-dihydropyrans by three-component 'one-pot' reaction
Fulltext Access 12 Pages 2016
Contents (graphical abstracts and research highlights)
Fulltext Access 12 Pages 2016
Silver-catalyzed organic reactions of isocyanides
Fulltext Access 12 Pages 2016
Easily oxidizable triarylamine materials with naphthalene and binaphthalene core: structure-properties relationship
Fulltext Access 12 Pages 2016
Nucleophilic aromatic substitution of heterocycles using a high-temperature and high-pressure flow reactor
Fulltext Access 12 Pages 2016
Synthesis and photophysical studies of fluorenone-armed porphyrin arrays
Fulltext Access 12 Pages 2016
An easy access to fused chromanones via rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins
Fulltext Access 12 Pages 2016
Recent developments in oxidative esterification and amidation of aldehydes
Fulltext Access 12 Pages 2016
Recent developments in Tsuji-Wacker oxidation
Fulltext Access 12 Pages 2016
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