Designing new readily available sugar-based ligands for asymmetric transfer hydrogenation of ketones. In the quest to expand the substrate scope Fulltext Access 10 Pages 2016
Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice Fulltext Access 10 Pages 2016
Invited reviewThe histaminergic system as a target for the prevention of obesity and metabolic syndrome Fulltext Access 10 Pages 2016
Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors Fulltext Access 10 Pages 2016
Effects of iloperidone, combined with desipramine, on alcohol drinking in the Syrian golden hamster Fulltext Access 10 Pages 2016
Glucocorticoids alter neuronal differentiation of human neuroepithelial-like cells by inducing long-lasting changes in the reactive oxygen species balance Fulltext Access 10 Pages 2016
Rapid stress-induced transcriptomic changes in the brain depend on beta-adrenergic signaling Fulltext Access 10 Pages 2016
κ Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice Fulltext Access 10 Pages 2016
Lateral hypothalamus orexinergic system modulates the stress effect on pentylenetetrazol induced seizures through corticotropin releasing hormone receptor type 1 Fulltext Access 10 Pages 2016
The role of regulation in the origin and synthetic modelling of minimal cognition Fulltext Access 10 Pages 2016
A novel stereoselective [8+2] double cycloaddition route to hydronaphthalene ring systems Fulltext Access 10 Pages 2016
Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity Fulltext Access 10 Pages 2016
Synthesis and chemical reactivity of new zinc porphyrin diazoacetates catalyzed by ruthenium and iron porphyrins Fulltext Access 10 Pages 2016
Acid-promoted transformations of aryl substituted diphenylphosphoryl allenes Fulltext Access 10 Pages 2016
Recent developments in chemical degradation of lignin: catalytic oxidation and ionic liquids Fulltext Access 10 Pages 2016
Facile synthesis of densely substituted chroman derivatives through Brønsted acid ionic liquid catalyzed three-component reactions of aromatic aldehydes, 1,1-diarylethylenes and nucleophiles Fulltext Access 10 Pages 2016
Catalytic asymmetric transfer hydrogenation/dynamic kinetic resolution: an efficient synthesis of florfenicol Fulltext Access 10 Pages 2016
Unexpected formation of 5-alkylidene derivatives of hydantoin from the Michael addition of 4-phenylurazole to fumaric esters Fulltext Access 10 Pages 2016
Quantum chemical exploration on the metabolic mechanisms of caffeine by flavin-containing monooxygenase Fulltext Access 10 Pages 2016
Regioselectivity of the ortho- and para-semidine, and diphenyline rearrangements Fulltext Access 10 Pages 2016
Synthesis of stable tetrahedral intermediates (hemiaminals) and kinetics of their conversion to thiazol-2-imines Fulltext Access 10 Pages 2016
Reagent-switch controlled metal-free intermolecular geminal diamination and aminooxygenation of vinylarenes Fulltext Access 10 Pages 2016
Transcriptional dysregulation causes altered modulation of inhibition by haloperidol Fulltext Access 10 Pages 2016
The role of the 14-3-3 protein family in health, disease, and drug development Fulltext Access 10 Pages 2016
Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases Fulltext Access 10 Pages 2016
Stabilization of protein-protein interaction complexes through small molecules Fulltext Access 10 Pages 2016
Synthesis, characterization, theoretical prediction of activities and evaluation of biological activities of some sulfacetamide based hydroxytriazenes Fulltext Access 10 Pages 2016
Efficient synthesis of new 2,3-dihydrooxazole-spirooxindoles hybrids as antimicrobial agents Fulltext Access 10 Pages 2016
Hyaluronan-Lysine Cisplatin Drug Carrier for Treatment of Localized Cancers: Pharmacokinetics, Tolerability, and Efficacy in Rodents and Canines Fulltext Access 10 Pages 2016
Prediction of Protein Aggregation in High Concentration Protein Solutions Utilizing Protein-Protein Interactions Determined by Low Volume Static Light Scattering Fulltext Access 10 Pages 2016
Regioselective mono and multiple alkylation of diols and polyols catalyzed by organotin and its applications on the synthesis of value-added carbohydrate intermediates Fulltext Access 10 Pages 2016
Exploratory Investigation of the Limiting Steps of Oral Absorption of Fluconazole and Ketoconazole in Children Using an In Silico Pediatric Absorption Model Fulltext Access 10 Pages 2016
Virtual Clinical Trial Toward Polytherapy Safety Assessment: Combination of Physiologically Based Pharmacokinetic/Pharmacodynamic-Based Modeling and Simulation Approach With Drug-Drug Interactions Involving Terfenadine as an Example Fulltext Access 10 Pages 2016
Formulation and Characterization of Nanocluster Ceftazidime for the Treatment of Acute Pulmonary Melioidosis Fulltext Access 10 Pages 2016
On the time to reach a critical number of infections in epidemic models with infective and susceptible immigrants Fulltext Access 10 Pages 2016
Advances in the integration of transcriptional regulatory information into genome-scale metabolic models Fulltext Access 10 Pages 2016
Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease Fulltext Access 10 Pages 2016
Computer-aided identification of new histone deacetylase 6 selective inhibitor with anti-sepsis activity Fulltext Access 10 Pages 2016
Design, synthesis, broad-spectrum antiproliferative activity, and kinase inhibitory effect of triarylpyrazole derivatives possessing arylamides or arylureas moieties Fulltext Access 10 Pages 2016
Synthesis and biological properties of polyamine modified flavonoids as hepatocellular carcinoma inhibitors Fulltext Access 10 Pages 2016
Preparation, characterization and photostability assessment of curcumin microencapsulated within methacrylic copolymers Fulltext Access 10 Pages 2016
Fabrication of acetylated dioscorea starch nanoparticles: Optimization of formulation and process variables Fulltext Access 10 Pages 2016
In-vitro evaluation of griseofulvin loaded lipid nanoparticles for topical delivery Fulltext Access 10 Pages 2016
Ocular inserts based on chitosan and brimonidine tartrate: Development, characterization and biocompatibility Fulltext Access 10 Pages 2016
Size-induced segregation during pharmaceutical particle die filling assessed by response surface methodology using discrete element method Fulltext Access 10 Pages 2016
In situ thermosensitive Tamoxifen citrate loaded hydrogels: An effective tool in breast cancer loco-regional therapy Fulltext Access 10 Pages 2016
Formulation and in vitro characterization of a composite biodegradable scaffold as antibiotic delivery system and regenerative device for bone Fulltext Access 10 Pages 2016
Pharmacokinetics, bioavailability, metabolism and excretion of δ-viniferin in rats Fulltext Access 10 Pages 2016
Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges Fulltext Access 10 Pages 2016
Relative stability of network states in Boolean network models of gene regulation in development Fulltext Access 10 Pages 2016
Development and Characterization of Sodium Hyaluronate Microparticle-Based Sustained Release Formulation of Recombinant Human Growth Hormone Prepared by Spray-Drying Fulltext Access 10 Pages 2016
Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity Fulltext Access 10 Pages 2016
Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors Fulltext Access 10 Pages 2016
Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound Fulltext Access 10 Pages 2016
Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents Fulltext Access 10 Pages 2016
The biphosphinic paladacycle complex induces melanoma cell death through lysosomal–mitochondrial axis modulation and impaired autophagy Fulltext Access 10 Pages 2016
Comparative study of structural models of Leishmania donovani and human GDP-mannose pyrophosphorylases Fulltext Access 10 Pages 2016
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis Fulltext Access 10 Pages 2016
Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities Fulltext Access 10 Pages 2016
Substituted quinazolinones as kinase inhibitors endowed with anti-fibrotic properties Fulltext Access 10 Pages 2016
Characterization of Factors Affecting Nanoparticle Tracking Analysis Results With Synthetic and Protein Nanoparticles Fulltext Access 10 Pages 2016
Aromatic changes in isoelectronic derivatives of phenalenyl radicals by central carbon replacement Fulltext Access 10 Pages 2016
Synthesis of polybenzoquinazolines via an intramolecular dehydration of photocyclization Fulltext Access 10 Pages 2016
Dipeptide-derived multifunctional phosphonium salt as a catalyst to synthesize highly functionalized chiral cyclopentanes Fulltext Access 10 Pages 2016
Enhanced liquid crystal properties in symmetric ethers containing the oxazepine core: synthesis and characterization of seven member heterocyclic dimers Fulltext Access 10 Pages 2016
Influence of a remote sulfinyl group on l-proline-catalyzed direct asymmetric aldol addition of acetone Fulltext Access 10 Pages 2016
Aggregation propensity of amyloidogenic and elastomeric dipeptides constituents Fulltext Access 10 Pages 2016
Investigation of highly selective regenerative cellulose microcolumn for selenium detection and efficient recovery Fulltext Access 10 Pages 2016
Identification and optimization of a new series of anti-tubercular quinazolinones Fulltext Access 10 Pages 2016
Extraction Method Plays Critical Role in Antibacterial Activity of Propolis-Loaded Hydrogels Fulltext Access 10 Pages 2016
Formulation of Granules for Site-Specific Delivery of an Antimicrobial Essential Oil to the Animal Intestinal Tract Fulltext Access 10 Pages 2016
Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for “Second Generation” Therapeutic Application Fulltext Access 10 Pages 2016
Design and synthesis of diamide-coupled benzophenones as potential anticancer agents Fulltext Access 10 Pages 2016
Preparation, Characterization, and Antitumor Activities of Miriplatin-Loaded Liposomes Fulltext Access 10 Pages 2016
A Universal Correlation Predicts Permeability Coefficients of Fluid- and Gel-Phase Phospholipid and Phospholipid-Cholesterol Bilayers for Arbitrary Solutes Fulltext Access 10 Pages 2016
Residual Host Cell Protein Promotes Polysorbate 20 Degradation in a Sulfatase Drug Product Leading to Free Fatty Acid Particles Fulltext Access 10 Pages 2016
Reduced Burst Release and Enhanced Oral Bioavailability in Shikimic Acid-Loaded Polylactic Acid Submicron Particles by Coaxial Electrospray Fulltext Access 10 Pages 2016
Effect of Common Excipients on the Oral Drug Absorption of Biopharmaceutics Classification System Class 3 Drugs Cimetidine and Acyclovir Fulltext Access 10 Pages 2016
Investigation Into Efficiency of a Novel Glycol Chitosan-Bestatin Conjugate to Protect Thymopoietin Oligopeptides From Enzymatic Degradation Fulltext Access 10 Pages 2016
Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions Fulltext Access 10 Pages 2016