Polymeric chloroquine as an inhibitor of cancer cell migration and experimental lung metastasis Fulltext Access 10 Pages 2016
Pharmacokinetics and metabolism profiles of protostemonine in rat by liquid chromatography combined with electrospray ionization tandem mass spectrometry Fulltext Access 10 Pages 2016
Monitoring utilizations of amino acids and vitamins in culture media and Chinese hamster ovary cells by liquid chromatography tandem mass spectrometry Fulltext Access 10 Pages 2016
Rapid quantification of a cleavable antibody-conjugated drug by liquid chromatography/tandem mass spectrometry with microwave-assisted enzymatic cleavage Fulltext Access 10 Pages 2016
Metabolic profile of 5-hydroxy-4-methoxycanthin-6-one, a typical canthinone alkaloid, in rats determined by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry together with multiple data processing techniques Fulltext Access 10 Pages 2016
Identification of markers of cancer in urban sewage through the use of a suspect screening approach Fulltext Access 10 Pages 2016
An integrated approach for profiling oxidative metabolites and glutathione adducts using liquid chromatography coupled with ultraviolet detection and triple quadrupole-linear ion trap mass spectrometry Fulltext Access 10 Pages 2016
Roller compaction scale-up using roll width as scale factor and laser-based determined ribbon porosity as critical material attribute Fulltext Access 10 Pages 2016
Research paperSolid lipid nanoparticles as promising tool for intraocular tobramycin delivery: Pharmacokinetic studies on rabbits Fulltext Access 10 Pages 2016
Lipopeptide-based micellar and liposomal carriers: Influence of surface charge and particle size on cellular uptake into blood brain barrier cells Fulltext Access 10 Pages 2016
Correlation between the chemical composition of thermoresponsive nanogels and their interaction with the skin barrier Fulltext Access 10 Pages 2016
Triethylated chromones with substituted naphthalenes as tubulin inhibitors Fulltext Access 10 Pages 2016
Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: A robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy Fulltext Access 10 Pages 2016
Light activated liposomes: Functionality and prospects in ocular drug delivery Fulltext Access 10 Pages 2016
Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents Fulltext Access 10 Pages 2016
Improvement of vascular function by magnetic nanoparticle-assisted circumferential gene transfer into the native endothelium Fulltext Access 10 Pages 2016
Co-release of dicloxacillin and thioridazine from catheter material containing an interpenetrating polymer network for inhibiting device-associated Staphylococcus aureus infection Fulltext Access 10 Pages 2016
Identification and optimization of a new series of anti-tubercular quinazolinones Fulltext Access 10 Pages 2016
Preparation, characterization and photostability assessment of curcumin microencapsulated within methacrylic copolymers Fulltext Access 10 Pages 2016
Fabrication of acetylated dioscorea starch nanoparticles: Optimization of formulation and process variables Fulltext Access 10 Pages 2016
In-vitro evaluation of griseofulvin loaded lipid nanoparticles for topical delivery Fulltext Access 10 Pages 2016
Meta-analysis of clinical and preclinical studies comparing the anticancer efficacy of liposomal versus conventional non-liposomal doxorubicin Fulltext Access 10 Pages 2016
Synthesis, characterization, theoretical prediction of activities and evaluation of biological activities of some sulfacetamide based hydroxytriazenes Fulltext Access 10 Pages 2016
Efficient synthesis of new 2,3-dihydrooxazole-spirooxindoles hybrids as antimicrobial agents Fulltext Access 10 Pages 2016
Synthesis and antiviral, insecticidal, and fungicidal activities of gossypol derivatives containing alkylimine, oxime or hydrazine moiety Fulltext Access 10 Pages 2016
Design and synthesis of peptide conjugates of phosphoramide mustard as prodrugs activated by prostate-specific antigen Fulltext Access 10 Pages 2016
Investigation of salt formation between memantine and pamoic acid: Its exploitation in nanocrystalline form as long acting injection Fulltext Access 10 Pages 2016
Co-milling of telmisartan with poly(vinyl alcohol) - An alkalinizer free green approach to ensure its bioavailability Fulltext Access 10 Pages 2016
Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin Fulltext Access 10 Pages 2016
Melanoma growth effects on molecular clearance from tumors and biodistribution into systemic tissues versus draining lymph nodes Fulltext Access 10 Pages 2016
Rotating magnetic field induced oscillation of magnetic particles for in vivo mechanical destruction of malignant glioma Fulltext Access 10 Pages 2016
Short-range cytokine gradients to mimic paracrine cell interactions in vitro Fulltext Access 10 Pages 2016
Controlling levonorgestrel binding and release in a multi-purpose prevention technology vaginal ring device Fulltext Access 10 Pages 2016
Ocular inserts based on chitosan and brimonidine tartrate: Development, characterization and biocompatibility Fulltext Access 10 Pages 2016
Perivascular sustained release of atorvastatin from a hydrogel-microparticle delivery system decreases intimal hyperplasia Fulltext Access 10 Pages 2016
Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model Fulltext Access 10 Pages 2016
Lung inflammation does not affect the clearance kinetics of lipid nanocapsules following pulmonary administration Fulltext Access 10 Pages 2016
Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy Fulltext Access 10 Pages 2016
Non-specific binding and steric hindrance thresholds for penetration of particulate drug carriers within tumor tissue Fulltext Access 10 Pages 2016
Engineered mesenchymal stem cells as vectors in a suicide gene therapy against preclinical murine models for solid tumors Fulltext Access 10 Pages 2016
5-Aminolevulinic acid coated microneedles for photodynamic therapy of skin tumors Fulltext Access 10 Pages 2016
An efficient protocol for obtaining accurate hydration free energies using quantum chemistry and reweighting from molecular dynamics simulations Fulltext Access 10 Pages 2016
Comparative study of structural models of Leishmania donovani and human GDP-mannose pyrophosphorylases Fulltext Access 10 Pages 2016
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis Fulltext Access 10 Pages 2016
Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities Fulltext Access 10 Pages 2016
Substituted quinazolinones as kinase inhibitors endowed with anti-fibrotic properties Fulltext Access 10 Pages 2016
Design and synthesis of diamide-coupled benzophenones as potential anticancer agents Fulltext Access 10 Pages 2016
Pharmacological protection of mitochondrial function mitigates acute limb ischemia/reperfusion injury Fulltext Access 10 Pages 2016
Design and synthesis of aminothiazole modulators of the gamma-secretase enzyme Fulltext Access 10 Pages 2016
Synthesis, isomerization and biological activity of novel 2-selenohydantoin derivatives Fulltext Access 10 Pages 2016
Synthesis, and anticonvulsant activity of new amides derived from 3-methyl- or 3-ethyl-3-methyl-2,5-dioxo-pyrrolidin-1-yl-acetic acids Fulltext Access 10 Pages 2016
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin Fulltext Access 10 Pages 2016
Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors Fulltext Access 10 Pages 2016
The biphosphinic paladacycle complex induces melanoma cell death through lysosomal–mitochondrial axis modulation and impaired autophagy Fulltext Access 10 Pages 2016
Functionalized imidazolium and benzimidazolium salts as paraoxonase 1 inhibitors: Synthesis, characterization and molecular docking studies Fulltext Access 10 Pages 2016
Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer’s disease Fulltext Access 10 Pages 2016
Extended rhodamine photosensitizers for photodynamic therapy of cancer cells Fulltext Access 10 Pages 2016
Clonidine complexation with hydroxypropyl-beta-cyclodextrin: From physico-chemical characterization to in vivo adjuvant effect in local anesthesia Fulltext Access 10 Pages 2016
Simultaneous determination of ceftaroline, daptomycin, linezolid and rifampicin concentrations in human plasma by on-line solid phase extraction coupled to high-performance liquid chromatography–tandem mass spectrometry Fulltext Access 10 Pages 2016
Analytical approaches to investigate salt disproportionation in tablet matrices by Raman spectroscopy and Raman mapping Fulltext Access 10 Pages 2016
An iterative approach for compound detection in an unknown pharmaceutical drug product: Application on Raman microscopy Fulltext Access 10 Pages 2016
Chiral separation of new designer drugs (Cathinones) on chiral ion-exchange type stationary phases Fulltext Access 10 Pages 2016
Simultaneous quantification of neuroactive dopamine serotonin and kynurenine pathway metabolites in gender-specific youth urine by ultra performance liquid chromatography tandem high resolution mass spectrometry Fulltext Access 10 Pages 2016
Metabonomic study of the fruits of Alpinia oxyphylla as an effective treatment for chronic renal injury in rats Fulltext Access 10 Pages 2016
Determination of benzophenones in lipophilic extract of Brazilian red propolis, nanotechnology-based product and porcine skin and mucosa: Analytical and bioanalytical assays Fulltext Access 10 Pages 2016
Clinical efficacy and safety of eperisone for low back pain: A systematic literature review Fulltext Access 10 Pages 2016
Size-induced segregation during pharmaceutical particle die filling assessed by response surface methodology using discrete element method Fulltext Access 10 Pages 2016
In situ thermosensitive Tamoxifen citrate loaded hydrogels: An effective tool in breast cancer loco-regional therapy Fulltext Access 10 Pages 2016
Formulation and in vitro characterization of a composite biodegradable scaffold as antibiotic delivery system and regenerative device for bone Fulltext Access 10 Pages 2016
A novel formulation for solubility and content uniformity enhancement of poorly water-soluble drugs using highly-porous mannitol Fulltext Access 10 Pages 2016
Development and in vitro evaluation of core–shell type lipid–polymer hybrid nanoparticles for the delivery of erlotinib in non-small cell lung cancer Fulltext Access 10 Pages 2016
In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis Fulltext Access 10 Pages 2016
Development and evaluation of wound healing hydrogels based on a quinolone, hydroxypropyl methylcellulose and biodegradable microfibres Fulltext Access 10 Pages 2016
Pharmacokinetics, bioavailability, metabolism and excretion of δ-viniferin in rats Fulltext Access 10 Pages 2016
Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges Fulltext Access 10 Pages 2016
Treatment strategies for advanced hormone receptor-positive and human epidermal growth factor 2-negative breast cancer: the role of treatment order Fulltext Access 10 Pages 2016
Stability behaviour of antiretroviral drugs and their combinations. 4: Characterization of degradation products of tenofovir alafenamide fumarate and comparison of its degradation and stability behaviour with tenofovir disoproxil fumarate Fulltext Access 10 Pages 2016
Brain ischemia with Alzheimer phenotype dysregulates Alzheimer's disease-related proteins Fulltext Access 10 Pages 2016
Common links between metabolic syndrome and inflammatory bowel disease: Current overview and future perspectives Fulltext Access 10 Pages 2016
Can exercise affect the course of inflammatory bowel disease? Experimental and clinical evidence Fulltext Access 10 Pages 2016
Ethylene glycol ethers induce apoptosis and disturb glucose metabolism in the rat brain Fulltext Access 10 Pages 2016
Drug nanoparticles by emulsion-freeze-drying via the employment of branched block copolymer nanoparticles Fulltext Access 10 Pages 2016
Bioabsorbable bone plates enabled with local, sustained delivery of alendronate for bone regeneration Fulltext Access 10 Pages 2016
Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma Fulltext Access 10 Pages 2016
Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis Fulltext Access 10 Pages 2016
Synthesis and antiproliferative activity of a natural like glycoconjugate polycyclic compound Fulltext Access 10 Pages 2016
Design, synthesis and evaluation of 4-dimethylamine flavonoid derivatives as potential multifunctional anti-Alzheimer agents Fulltext Access 10 Pages 2016