Characterization and physical stability of fast-dissolving microparticles containing nifedipine Fulltext Access 10 Pages 2008
Formation and physical stability of the amorphous phase of ranitidine hydrochloride polymorphs prepared by cryo-milling Fulltext Access 10 Pages 2008
Standardization, evaluation and early-phase method validation of an analytical scheme for batch-consistency N-glycosylation analysis of recombinant produced glycoproteins Fulltext Access 10 Pages 2008
Monitoring galenical process development by near infrared chemical imaging: One case study Fulltext Access 10 Pages 2008
Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery Fulltext Access 10 Pages 2008
Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method Fulltext Access 10 Pages 2008
Dexamethasone-loaded poly(ε-caprolactone) intravitreal implants: A pilot study Fulltext Access 10 Pages 2008
Chitosan microspheres for intrapulmonary administration of moxifloxacin: Interaction with biomembrane models and in vitro permeation studies Fulltext Access 10 Pages 2008
Inulin–iron complexes: A potential treatment of iron deficiency anaemia Fulltext Access 10 Pages 2008
In vitro skin absorption and drug release – A comparison of six commercial prednicarbate preparations for topical use Fulltext Access 10 Pages 2008
Establishment and validation of an ex vivo human cervical tissue model for local delivery studies Fulltext Access 10 Pages 2008
Grafting of abciximab to a microbubble-based ultrasound contrast agent for targeting to platelets expressing GP IIb/IIIa – Characterization and in vitro testing Fulltext Access 10 Pages 2008
Modeling therapy resistance in genetically engineered mouse cancer models Fulltext Access 10 Pages 2008
Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells Fulltext Access 10 Pages 2008
Cyclosporine-loaded solid lipid nanoparticles (SLN®): Drug–lipid physicochemical interactions and characterization of drug incorporation Fulltext Access 10 Pages 2008
Application of the SeDeM Diagram and a new mathematical equation in the design of direct compression tablet formulation Fulltext Access 11 Pages 2008
Polypropylene grafted with smart polymers (PNIPAAm/PAAc) for loading and controlled release of vancomycin Fulltext Access 11 Pages 2008
Role of trehalose in moisture-induced aggregation of bovine serum albumin Fulltext Access 11 Pages 2008
Enhancement of famotidine dissolution rate through liquisolid tablets formulation: In vitro and in vivo evaluation Fulltext Access 11 Pages 2008
Supramolecular organization and release properties of phospholipid-hyaluronan microparticles encapsulating dexamethasone Fulltext Access 11 Pages 2008
Particle design of poorly water-soluble drug substances using supercritical fluid technologies Fulltext Access 11 Pages 2008
Supercritical carbon dioxide processing of active pharmaceutical ingredients for polymorphic control and for complex formation Fulltext Access 11 Pages 2008
Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers Fulltext Access 11 Pages 2008
Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy Fulltext Access 11 Pages 2008
Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants Fulltext Access 11 Pages 2008
Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers Fulltext Access 11 Pages 2008
Multifunctional magnetic nanoparticles for targeted imaging and therapy Fulltext Access 11 Pages 2008
Physicochemical characterization of five glyburide powders: A BCS based approach to predict oral absorption Fulltext Access 11 Pages 2008
Improved formulation of photosensitizer chlorin e6 polyvinylpyrrolidone for fluorescence diagnostic imaging and photodynamic therapy of human cancer Fulltext Access 11 Pages 2008
Application of PGSTE-NMR technique to characterize the porous structure of pharmaceutical tablets Fulltext Access 11 Pages 2008
Development of enteric-coated calcium pectinate microspheres intended for colonic drug delivery Fulltext Access 11 Pages 2008
Triclosan-loaded poloxamine micelles for enhanced topical antibacterial activity against biofilm Fulltext Access 11 Pages 2008
Performance of an in vitro mucoadhesion testing method for vaginal semisolids: Influence of different testing conditions and instrumental parameters Fulltext Access 11 Pages 2008
Incidence of drying on microstructure and drug release profiles from tablets of MCC–lactose–Carbopol® and MCC–dicalcium phosphate–Carbopol® pellets Fulltext Access 11 Pages 2008
Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology Fulltext Access 11 Pages 2008
Polyoxyethylated nonionic surfactants and their applications in topical ocular drug delivery Fulltext Access 11 Pages 2008
Chitosan-based spray-dried respirable powders for sustained delivery of terbutaline sulfate Fulltext Access 11 Pages 2008
A sugar cane native dextran as an innovative functional excipient for the development of pharmaceutical tablets Fulltext Access 11 Pages 2008
Method transfer for fast liquid chromatography in pharmaceutical analysis: Application to short columns packed with small particle. Part II: Gradient experiments Fulltext Access 11 Pages 2008
Progress and challenges in the identification of biomarkers for EGFR and VEGFR targeting anticancer agents Fulltext Access 11 Pages 2008
A new class of analgesic agents toward prostacyclin receptor inhibition: Synthesis, biological studies and QSAR analysis of 1-hydroxyl-2-substituted phenyl-4,4,5,5-tetramethylimidazolines Fulltext Access 11 Pages 2008
1,8-Naphthyridines VI. Synthesis and anti-inflammatory activity of 5-(alkylamino)-N,N-diethyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides with a new substitution pattern on the triazole ring Fulltext Access 11 Pages 2008
Three-dimensional QSAR analyses of 1,3,4-trisubstituted pyrrolidine-based CCR5 receptor inhibitors Fulltext Access 11 Pages 2008
1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: Synthesis and preliminary evaluation of biological properties Fulltext Access 11 Pages 2008
Structure–activity relationships in the acronycine and benzo[b]acronycine series: Role of the pyran ring Fulltext Access 11 Pages 2008
Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases Fulltext Access 11 Pages 2008
Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles Fulltext Access 11 Pages 2008
A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5) Fulltext Access 11 Pages 2008
Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps Fulltext Access 11 Pages 2008
Towards predictive inhibitor design for the EGFR autophosphorylation activity Fulltext Access 11 Pages 2008
Synthesis and in vitro antibacterial activities of novel oxazolidinones Fulltext Access 11 Pages 2008
Structure–activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues Fulltext Access 11 Pages 2008
Aldehyde dehydrogenase inhibitors: α,β-Acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture Fulltext Access 11 Pages 2008
QSAR analysis of 1,3-diaryl-4,5,6,7-tetrahydro-2H-isoindole derivatives as selective COX-2 inhibitors Fulltext Access 11 Pages 2008
Syntheses of 4-(indole-3-yl)quinazolines – A new class of epidermal growth factor receptor tyrosine kinase inhibitors Fulltext Access 11 Pages 2008
In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors Fulltext Access 11 Pages 2008
CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example Fulltext Access 11 Pages 2008
Synthesis of novel aminoquinonoid analogues of diospyrin and evaluation of their inhibitory activity against murine and human cancer cells Fulltext Access 11 Pages 2008
Structure–activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents Fulltext Access 11 Pages 2008
Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: In silico, in vitro and in vivo activity studies Fulltext Access 11 Pages 2008
Synthesis and biological activities of some new fluorinated coumarins and 1-aza coumarins Fulltext Access 11 Pages 2008
Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity Fulltext Access 11 Pages 2008
Condensed bridgehead nitrogen heterocyclic system: Synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid Fulltext Access 11 Pages 2008
Molecular interactions, internal structure and drug release kinetics of rationally developed polymer–lipid hybrid nanoparticles Fulltext Access 11 Pages 2008
Advances in lipid nanodispersions for parenteral drug delivery and targeting Fulltext Access 11 Pages 2008
Drug release from injectable biodegradable polymeric adhesives for bone repair Fulltext Access 11 Pages 2008
Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: In vitro effect of extra drug-free GlyPheLeuGly sequences Fulltext Access 11 Pages 2008
DNA condensation by poly-l-lysine at the single molecule level: Role of DNA concentration and polymer length Fulltext Access 11 Pages 2008
Delivery of siRNA mediated by histidine-containing reducible polycations Fulltext Access 11 Pages 2008
Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel Fulltext Access 11 Pages 2008
Liposomes-mediated delivery of pro-apoptotic therapeutic membrane proteins Fulltext Access 11 Pages 2008
Temoporfin-loaded invasomes: Development, characterization and in vitro skin penetration studies Fulltext Access 11 Pages 2008
The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery Fulltext Access 11 Pages 2008
Chemical imaging of drug eluting coatings: Combining surface analysis and confocal Raman microscopy Fulltext Access 11 Pages 2008
Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy Fulltext Access 11 Pages 2008
Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline Fulltext Access 11 Pages 2008
Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS Fulltext Access 11 Pages 2008
New cerium(III) complexes of coumarins – Synthesis, characterization and cytotoxicity evaluation Fulltext Access 11 Pages 2008
Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: A critical revisitation Fulltext Access 11 Pages 2008
Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids Fulltext Access 11 Pages 2008
N-[2-(5,5-Dimethyl-1,3-dioxane-2-yl)ethyl]amino acids: Their synthesis, anti-inflammatory evaluation and QSAR analysis Fulltext Access 11 Pages 2008
Novel Pd(II) complexes of 1-N-substituted 3-phenyl-2-pyrazoline derivatives and evaluation of antiamoebic activity Fulltext Access 11 Pages 2008
Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone Fulltext Access 11 Pages 2008
Design and microwave-assisted synthesis of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles: Novel agents with analgesic and anti-inflammatory properties Fulltext Access 11 Pages 2008
Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives Fulltext Access 11 Pages 2008
Syntheses of tetrahydroisoquinoline derivatives that inhibit NO production in activated BV-2 microglial cells Fulltext Access 11 Pages 2008