Phosphatidylinositol mannosides: Synthesis and suppression of allergic airway disease Fulltext Access 11 Pages 2006
Hsp70 accumulation and ultrastructural features of lung and liver induced by ethanol treatment with and without l-carnitine protection in rats Fulltext Access 11 Pages 2006
Suitability of 5/6 nephrectomy (5/6NX) for the induction of interstitial renal fibrosis in rats – Influence of sex, strain, and surgical procedure Fulltext Access 11 Pages 2006
Renal dysfunction as a consequence of acute liver damage by bile duct ligation in cirrhotic rats Fulltext Access 11 Pages 2006
Differentiation of spontaneous and induced mammary adenocarcinomas of the rat by gene expression profiling Fulltext Access 11 Pages 2006
Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-d-xylulose 5-phosphate reductoisomerase Fulltext Access 11 Pages 2006
Synthesis and anti-HIV activity of bi-functional betulinic acid derivatives Fulltext Access 11 Pages 2006
Syntheses and evaluation of fluorinated conformationally restricted analogues of GABA as potential inhibitors of GABA aminotransferase Fulltext Access 11 Pages 2006
Binding of oxalyl derivatives of β-d-glucopyranosylamine to muscle glycogen phosphorylase b Fulltext Access 11 Pages 2006
Synthesis and radiosynthesis of [18F]FPhEP, a novel α4β2-selective, epibatidine-based antagonist for PET imaging of nicotinic acetylcholine receptors Fulltext Access 11 Pages 2006
Synthesis and CYP26A1 inhibitory activity of 1-[benzofuran-2-yl-(4-alkyl/aryl-phenyl)-methyl]-1H-triazoles Fulltext Access 11 Pages 2006
Subcutaneous microchip-associated tumours in B6C3F1 mice: A retrospective study to attempt to determine their histogenesis Fulltext Access 11 Pages 2006
Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline γ- and δ-lactams via a ‘catch and release’ protocol Fulltext Access 11 Pages 2006
Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the μ-opioid receptor and I2–imidazoline binding sites Fulltext Access 11 Pages 2006
Synthesis and in vitro antitumor evaluation of some indeno[1,2-c]pyrazol(in)es substituted with sulfonamide, sulfonylurea(-thiourea) pharmacophores, and some derived thiazole ring systems Fulltext Access 11 Pages 2006
Synthesis and conformational analysis of His-Phe-Arg-Trp-NH2 and analogues with antifungal properties Fulltext Access 11 Pages 2006
Amino- and glycoconjugates of pyrido[4,3,2-kl]acridine. Synthesis, antitumor activity, and DNA binding Fulltext Access 11 Pages 2006
Novel potent neuropeptide Y Y5 receptor antagonists: Synthesis and structure–activity relationships of phenylpiperazine derivatives Fulltext Access 11 Pages 2006
Exploring the limits of benzimidazole DNA-binding oligomers for the hypoxia inducible factor (HIF) site Fulltext Access 11 Pages 2006
Modification at the C9 position of the marine natural product isoaaptamine and the impact on HIV-1, mycobacterial, and tumor cell activity Fulltext Access 11 Pages 2006
Novel non-classical C9-methyl-5-substituted-2,4-diaminopyrrolo[2,3-d]pyrimidines as potential inhibitors of dihydrofolate reductase and as anti-opportunistic agents Fulltext Access 11 Pages 2006
Synthesis and antitubercular activity of substituted phenylmethyl- and pyridylmethyl amines Fulltext Access 11 Pages 2006
Evaluation of melt granulation and ultrasonic spray congealing as techniques to enhance the dissolution of praziquantel Fulltext Access 11 Pages 2006
Nanoparticle formulation may affect the stabilization of an antiischemic prodrug Fulltext Access 11 Pages 2006
PEO and MPEG in high drug load extruded and spheronized beads that are devoid of MCC Fulltext Access 11 Pages 2006
Citric acid prolongs the gastro-retention of a floating dosage form and increases bioavailability of riboflavin in the fasted state Fulltext Access 11 Pages 2006
A pilot study of freeze drying of poly(epsilon-caprolactone) nanocapsules stabilized by poly(vinyl alcohol): Formulation and process optimization Fulltext Access 11 Pages 2006
Application of TZERO calibrated modulated temperature differential scanning calorimetry to characterize model protein formulations Fulltext Access 11 Pages 2006
PLGA microcapsules with novel dimpled surfaces for pulmonary delivery of DNA Fulltext Access 11 Pages 2006
Properties of sustained release hot-melt extruded tablets containing chitosan and xanthan gum Fulltext Access 11 Pages 2006
Enhancement of drug affinity for cell membranes by conjugation with lipoamino acids Fulltext Access 11 Pages 2006
Evaluation of ciprofloxacin-loaded Eudragit® RS100 or RL100/PLGA nanoparticles Fulltext Access 11 Pages 2006
Torque rheological parameters to predict pellet quality in extrusion–spheronization Fulltext Access 11 Pages 2006
A thermo- and pH-sensitive hydrogel composed of quaternized chitosan/glycerophosphate Fulltext Access 11 Pages 2006
Lectin anchored stabilized biodegradable nanoparticles for oral immunization: 1. Development and in vitro evaluation Fulltext Access 11 Pages 2006
Aryl nucleoside H-phosphonates. Part 15: Synthesis, properties and, anti-HIV activity of aryl nucleoside 5′-α-hydroxyphosphonates Fulltext Access 11 Pages 2006
Cationic liposomes as potential carriers for ocular administration of peptides with anti-herpetic activity Fulltext Access 11 Pages 2006
Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice Fulltext Access 11 Pages 2006
Nifedipine solid dispersion in microparticles of ammonio methacrylate copolymer and ethylcellulose binary blend for controlled drug delivery: Effect of drug loading on release kinetics Fulltext Access 11 Pages 2006
Recombinant human parathyroid hormone 1–34: Pharmacokinetics, tissue distribution and excretion in rats Fulltext Access 11 Pages 2006
Detection of the breakage of pharmaceutical tablets in pneumatic transport Fulltext Access 11 Pages 2006
A century of dissolution research: From Noyes and Whitney to the Biopharmaceutics Classification System Fulltext Access 11 Pages 2006
The release dynamics of model drugs from the psyllium and N-hydroxymethylacrylamide based hydrogels Fulltext Access 11 Pages 2006
Nanoscopic core-shell drug carriers made of amphiphilic triblock and star-diblock copolymers Fulltext Access 11 Pages 2006
Encapsulation of lipophilic drugs within enteric microparticles by a novel coacervation method Fulltext Access 11 Pages 2006
Solid state characterization of olanzapine polymorphs using vibrational spectroscopy Fulltext Access 11 Pages 2006
Development of a laser diffraction method for the determination of the particle size of aerosolised powder formulations Fulltext Access 11 Pages 2006
Application of coulometric electrode array detection to the analysis of isoflavonoids and lignans Fulltext Access 11 Pages 2006
Synthesis and hydrolytic behavior of two novel tripartate codrugs of naltrexone and 6β-naltrexol with hydroxybupropion as potential alcohol abuse and smoking cessation agents Fulltext Access 11 Pages 2006
Substituent activity relationship studies on new azolo benzoxazepinyl oxazolidinones Fulltext Access 11 Pages 2006
Novel chemo-enzymatic oligomers of cinnamic acids as direct and indirect inhibitors of coagulation proteinases Fulltext Access 11 Pages 2006
Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site Fulltext Access 11 Pages 2006
Investigation of degradation products in a topical gel containing erythromycin and benzoyl peroxide by liquid chromatography–mass spectrometry Fulltext Access 11 Pages 2006
Evaluation of chemometric techniques to select orthogonal chromatographic systems Fulltext Access 11 Pages 2006
Recent advances in pharmaceutical applications of chiral capillary electrophoresis Fulltext Access 11 Pages 2006
Application of LC–ESI–MS–MS for detection of synthetic adulterants in herbal remedies Fulltext Access 11 Pages 2006
Liquid chromatographic-electrospray ionization mass spectrometric quantitative analysis of buprenorphine, norbuprenorphine, nordiazepam and oxazepam in rat plasma Fulltext Access 11 Pages 2006
Identification of impurities in ivermectin bulk material by mass spectrometry and NMR Fulltext Access 11 Pages 2006
Thrombomodulin induction in cultured human endothelial cells by 9-cis-locked retinoic acid analogues Fulltext Access 11 Pages 2006
Determination of albuterol sulfate and its related substances in albuterol sulfate inhalation solution, 0.5% by RP-HPLC Fulltext Access 11 Pages 2006
Screening a library of potential prion therapeutics against cellular prion proteins and insights into their mode of biological activities by surface plasmon resonance Fulltext Access 11 Pages 2006
Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-β-carboline formation Fulltext Access 11 Pages 2006
Bioactive polyacetylenes in food plants of the Apiaceae family: Occurrence, bioactivity and analysis Fulltext Access 11 Pages 2006
Experimental design for in vitro skin penetration study of liposomal superoxide dismutase Fulltext Access 11 Pages 2006
Composition analysis of two batches of polysorbate 60 using MS and NMR techniques Fulltext Access 11 Pages 2006
Application of 2-acetylbutyrolactone to spectrofluorimetry: Fluorescence properties of Schiff bases derived from 2-acetylbutyrolactone and spectrofluorimetric determination of primary amine-containing compounds Fulltext Access 11 Pages 2006
Quantification of recombinant human parathyroid hormone (rhPTH(1-84)) in human plasma by immunoassay: Commercial kit evaluation and validation to support pharmacokinetic studies Fulltext Access 11 Pages 2006
A new validation approach applied to the GC determination of impurities in organic solvents Fulltext Access 11 Pages 2006
Synthesis and biological activity of novel 4,4-difluorobenzazepine derivatives as non-peptide antagonists of the arginine vasopressin V1A receptor Fulltext Access 11 Pages 2006
Biomimetic synthesis, antimicrobial, antileishmanial and antimalarial activities of euglobals and their analogues Fulltext Access 11 Pages 2006
Synthesis and biological evaluation of 9-(5′,5′-difluoro-5′-phosphonopentyl)guanine derivatives for PNP-inhibitors Fulltext Access 11 Pages 2006
Structure–activity relationships of a series of tariquidar analogs as multidrug resistance modulators Fulltext Access 11 Pages 2006
Elucidation of sulfadoxine resistance with structural models of the bifunctional Plasmodium falciparum dihydropterin pyrophosphokinase–dihydropteroate synthase Fulltext Access 11 Pages 2006
Neamine derivatives having a nucleobase with a lysine or an arginine as a linker, their synthesis and evaluation as potential inhibitors for HIV TAR–Tat Fulltext Access 11 Pages 2006
α-Peptide/β-sulfonamidopeptide hybrids: Analogs of the chemotactic agent for-Met-Leu-Phe-OMe Fulltext Access 11 Pages 2006
Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: Nitric oxide-donor naproxen prodrugs Fulltext Access 11 Pages 2006
Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors Fulltext Access 11 Pages 2006
Applications of mass spectrometry in early stages of target based drug discovery Fulltext Access 11 Pages 2006
2,4-Diamino-9H-pyrimido[4,5-b]indol-5-ols: Synthesis, in vitro cytotoxic activity, and QSAR investigations Fulltext Access 11 Pages 2006
Synthesis and biological assays of E-ring analogs of camptothecin and homocamptothecin Fulltext Access 11 Pages 2006
Synthesis of docosahexaenoic acid derivatives designed as novel PPARγ agonists and antidiabetic agents Fulltext Access 11 Pages 2006
2D Autocorrelation modeling of the negative inotropic activity of calcium entry blockers using Bayesian-regularized genetic neural networks Fulltext Access 11 Pages 2006
Synthesis and biological evaluation of acyclic triaryl (Z)-olefins possessing a 3,5-di-tert-butyl-4-hydroxyphenyl pharmacophore: Dual inhibitors of cyclooxygenases and lipoxygenases Fulltext Access 11 Pages 2006
Immobilized methyltrioxo rhenium (MTO)/H2O2 systems for the oxidation of lignin and lignin model compounds Fulltext Access 11 Pages 2006
Synthesis and structure–activity relationship studies of 4,11-diaminonaphtho[2,3-f]indole-5,10-diones Fulltext Access 11 Pages 2006
Anticancer thiopyrano[2,3-d][1,3]thiazol-2-ones with norbornane moiety. Synthesis, cytotoxicity, physico-chemical properties, and computational studies Fulltext Access 11 Pages 2006
3-Aza-6,8-dioxabicyclo[3.2.1]octanes as new enantiopure heteroatom-rich tropane-like ligands of human dopamine transporter Fulltext Access 11 Pages 2006