The effects of albumin-coated microbubbles in DNA delivery mediated by therapeutic ultrasound Fulltext Access 11 Pages 2006
The quest for non-invasive delivery of bioactive macromolecules: A focus on heparins Fulltext Access 11 Pages 2006
Electrochemically controlled release of dexamethasone from conducting polymer polypyrrole coated electrode Fulltext Access 11 Pages 2006
Coadsorption of HIV-1 p24 and gp120 proteins to surfactant-free anionic PLA nanoparticles preserves antigenicity and immunogenicity Fulltext Access 11 Pages 2006
Molecular design of biodegradable polymeric micelles for temperature-responsive drug release Fulltext Access 11 Pages 2006
Properties of HPMA copolymer–doxorubicin conjugates with pH-controlled activation: Effect of polymer chain modification Fulltext Access 11 Pages 2006
Synthesis and characterization of novel poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery Fulltext Access 11 Pages 2006
siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene Fulltext Access 11 Pages 2006
Surfactant-free anionic PLA nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models Fulltext Access 11 Pages 2006
Triggered release of inhaled insulin from the agglomerated vesicles: Pharmacodynamic studies in rats Fulltext Access 11 Pages 2006
Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes Fulltext Access 11 Pages 2006
Characterizing the structure/function parameter space of hydrocarbon-conjugated branched polyethylenimine for DNA delivery in vitro Fulltext Access 11 Pages 2006
Cell delivery in regenerative medicine: The cell sheet engineering approach Fulltext Access 11 Pages 2006
Layer-by-layer coating of degradable microgels for pulsed drug delivery Fulltext Access 11 Pages 2006
Lipophilic prodrugs of Hsp90 inhibitor geldanamycin for nanoencapsulation in poly(ethylene glycol)-b-poly(ε-caprolactone) micelles Fulltext Access 11 Pages 2006
Enhancement of gene transfer activity mediated by mannosylated dendrimer/α-cyclodextrin conjugate (generation 3, G3) Fulltext Access 11 Pages 2006
Conjugates of poly(dl-lactic acid) with ethylenediamino or diethylenetriamino bridged bis(β-cyclodextrin)s and their nanoparticles as protein delivery systems Fulltext Access 11 Pages 2006
Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery Fulltext Access 11 Pages 2006
Copper–topotecan complexation mediates drug accumulation into liposomes Fulltext Access 11 Pages 2006
Les anévrysmes intracrâniens et leur traitement endovasculaire par l'utilisation de coils Fulltext Access 11 Pages 2006
Bacterial resistance: A sensitive issue: Complexity of the challenge and containment strategy in Europe Fulltext Access 11 Pages 2006
The proteasome as a potential target for novel anticancer drugs and chemosensitizers Fulltext Access 11 Pages 2006
In vitro toxicity to breast cancer cells of microsphere-delivered mitomycin C and its combination with doxorubicin Fulltext Access 11 Pages 2006
Preparation and release of salbutamol from chitosan and chitosan co-spray dried compacts and multiparticulates Fulltext Access 11 Pages 2006
Physicochemical characterization and drug release properties of Eudragit® E PO/Eudragit® L 100-55 interpolyelectrolyte complexes Fulltext Access 11 Pages 2006
Ophthalmic delivery systems based on drug–polymer–polymer ionic ternary interaction: In vitro and in vivo characterization Fulltext Access 11 Pages 2006
Xanthan gum to tailor drug release of sustained-release ethylcellulose mini-matrices prepared via hot-melt extrusion: in vitro and in vivo evaluation Fulltext Access 11 Pages 2006
Molecular docking study and development of an empirical binding free energy model for phosphodiesterase 4 inhibitors Fulltext Access 11 Pages 2006
Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology Fulltext Access 11 Pages 2006
Electron spin resonance microscopy applied to the study of controlled drug release Fulltext Access 11 Pages 2006
Modeling the release of proteins from degrading crosslinked dextran microspheres using kinetic Monte Carlo simulations Fulltext Access 11 Pages 2006
Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting Fulltext Access 11 Pages 2006
DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method Fulltext Access 11 Pages 2006
Fabrication and characterization of microfluidic probes for convection enhanced drug delivery Fulltext Access 11 Pages 2006
Studies on the chemistry of thienoanellated O,N- and S,N-containing heterocycles. Part 30: Synthesis and pharmacological properties of thieno[2,3-b][1,4]thiazines with potential vasopressin receptor antagonistic activity Fulltext Access 11 Pages 2006
Identification of chemically diverse Chk1 inhibitors by receptor-based virtual screening Fulltext Access 11 Pages 2006
Synthesis and characterization of selective dopamine D2 receptor antagonists Fulltext Access 11 Pages 2006
Constructing plasma protein binding model based on a combination of cluster analysis and 4D-fingerprint molecular similarity analyses Fulltext Access 11 Pages 2006
Novel 5-(2-hydroxyphenyl)-3-substituted-2,3-dihydro-1,3,4-oxadiazole-2-thione derivatives: Promising anticancer agents Fulltext Access 11 Pages 2006
Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET Fulltext Access 11 Pages 2006
Synthesis and biological evaluation of N-(7-indazolyl)benzenesulfonamide derivatives as potent cell cycle inhibitors Fulltext Access 11 Pages 2006
Building a successful structural motif into sialylmimetics—cyclohexenephosphonate monoesters as pseudo-sialosides with promising inhibitory properties Fulltext Access 11 Pages 2006
Synthesis of C-6 substituted pyrazolo[1,5-a]pyridines with potent activity against herpesviruses Fulltext Access 11 Pages 2006
Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination Fulltext Access 11 Pages 2006
Transformations of bioactive peptides in the presence of sugars—Characterization and stability studies of the adducts generated via the Maillard reaction Fulltext Access 11 Pages 2006
Synthesis and DNA cleavage reaction characteristics of enediyne prodrugs activated via an allylic rearrangement by base or UV irradiation Fulltext Access 11 Pages 2006
Synthesis and antimicrobial activity of new (4,4,4-trihalo-3-oxo-but-1-enyl)-carbamic acid ethyl esters, (4,4,4-trihalo-3-hydroxy-butyl)-carbamic acid ethyl esters, and 2-oxo-6-trihalomethyl-[1,3]oxazinane-3-carboxylic acid ethyl esters Fulltext Access 11 Pages 2006
Synthesis of pyrazole-based hybrid molecules: Search for potent multidrug resistance modulators Fulltext Access 11 Pages 2006
Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide Fulltext Access 11 Pages 2006
Preparation of antibodies against a novel immunosuppressant, FTY720, and development of an enzyme immunoassay for FTY720 Fulltext Access 11 Pages 2006
β-Nitrostyrene derivatives as potential antibacterial agents: A structure–property–activity relationship study Fulltext Access 11 Pages 2006
Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation Fulltext Access 11 Pages 2006
Atom-based 3D-chiral quadratic indices. Part 2: Prediction of the corticosteroid-binding globulinbinding affinity of the 31 benchmark steroids data set Fulltext Access 11 Pages 2006
Nonsteroidal antiinflammatory agents—part 2 antiinflammatory, analgesic and antipyretic activity of some substituted 3-pyrazolin-5-ones and 1,2,4,5,6,7-3H-hexahydroindazol-3-ones Fulltext Access 11 Pages 2006
Heterocyclic system containing bridgehead nitrogen atom: synthesis and pharmacological activities of some substituted 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles Fulltext Access 11 Pages 2006
In silico modelling of the interaction of flavonoids with human P-glycoprotein nucleotide-binding domain Fulltext Access 11 Pages 2006
Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors Fulltext Access 11 Pages 2006
Optimization of a pharmacophore model for 5-HT4 agonists using CoMFA and receptor based alignment Fulltext Access 11 Pages 2006
Acid-cleavable polymeric core–shell particles for delivery of hydrophobic drugs Fulltext Access 11 Pages 2006
Solid-phase synthesis and pharmacological evaluation of a library of peptidomimetics as potential farnesyltransferase inhibitors: an approach to new lead compounds Fulltext Access 11 Pages 2006
A dual-ligand approach for enhancing targeting selectivity of therapeutic nanocarriers Fulltext Access 11 Pages 2006
Novel 5,7-disubstituted 6-amino-5H-pyrrolo[3,2-b]pyrazine-2,3-dicarbonitriles, the promising protein kinase inhibitors with antiproliferative activity Fulltext Access 11 Pages 2006
Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 1: Synthesis and inhibitory activity of 5-(1-methyl-3-trifluoromethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamides Fulltext Access 11 Pages 2006
Synthesis and biological evaluation of homoserine lactone derived ureas as antagonists of bacterial quorum sensing Fulltext Access 11 Pages 2006
Non-stochastic quadratic fingerprints and LDA-based QSAR models in hit and lead generation through virtual screening: theoretical and experimental assessment of a promising method for the discovery of new antimalarial compounds Fulltext Access 11 Pages 2006
Application of PVP/HPMC miscible blends with enhanced mucoadhesive properties for adjusting drug release in predictable pulsatile chronotherapeutics Fulltext Access 12 Pages 2006
Spray-dried microparticles containing polymeric nanocapsules: Formulation aspects, liquid phase interactions and particles characteristics Fulltext Access 12 Pages 2006
Uptake characteristics of NGR-coupled stealth PEI/pDNA nanoparticles loaded with PLGA-PEG-PLGA tri-block copolymer for targeted delivery to human monocyte-derived dendritic cells Fulltext Access 12 Pages 2006
Changes in the amide I FT-IR bands of poly-l-lysine on spray-drying from α-helix, β-sheet or random coil conformations Fulltext Access 12 Pages 2006
Microemulsion and diafiltration approaches: An attempt to maximize the global yield of DNA-loaded nanospheres Fulltext Access 12 Pages 2006
Effect of hydrogen bonding interactions on the release mechanism of felodipine from nanodispersions with polyvinylpyrrolidone Fulltext Access 12 Pages 2006
DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity Fulltext Access 12 Pages 2006
Sterilization of gentamicin containing collagen/PLGA microparticle composites Fulltext Access 12 Pages 2006
Literature Highlights: Recent research in infectious disease drug resistance Fulltext Access 12 Pages 2006
Application and potential limitations of animal models utilized in the development of trastuzumab (Herceptin®): A case study Fulltext Access 12 Pages 2006
Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings Fulltext Access 12 Pages 2006
A peptide competing with VEGF165 binding on neuropilin-1 mediates targeting of a chlorin-type photosensitizer and potentiates its photodynamic activity in human endothelial cells Fulltext Access 12 Pages 2006
Polyethylenimine nanoparticles as efficient transfecting agents for mammalian cells Fulltext Access 12 Pages 2006
A recombinant human enzyme for enhanced interstitial transport of therapeutics Fulltext Access 12 Pages 2006
Polymer micelles with cross-linked ionic cores for delivery of anticancer drugs Fulltext Access 12 Pages 2006
Interaction of novel condensed triazine derivatives with central and peripheral type benzodiazepine receptors: synthesis, in vitro pharmacology and modelling Fulltext Access 12 Pages 2006
Novel derivatives of methyl and ethyl 2-(4-oxo-8-aryl-2H-3,4,6,7-tetrahydroimidazo[2,1-c][1,2,4]triazin-3-yl)acetates from biologically active 1-aryl-2-hydrazinoimidazolines: Synthesis, crystal structure and antiproliferative activity Fulltext Access 12 Pages 2006
Synthesis and cancer antiproliferative activity of new histone deacetylase inhibitors: hydrophilic hydroxamates and 2-aminobenzamide-containing derivatives Fulltext Access 12 Pages 2006
Synthesis and in vitro cytotoxicity of 1,2,3,4-tetrahydroisoquinoline derivatives Fulltext Access 12 Pages 2006
PEI-alginate nanocomposites as efficient in vitro gene transfection agents Fulltext Access 12 Pages 2006
Electronic speckle pattern interferometry: A novel non-invasive tool for studying drug transport rate through free films Fulltext Access 12 Pages 2006