Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles Fulltext Access 10 Pages 2006
Pharmaceutical and immunological evaluation of human papillomavirus viruslike particle as an antigen carrier Fulltext Access 10 Pages 2006
Intelligent thermoresponsive polymeric micelles for targeted drug delivery Fulltext Access 10 Pages 2006
The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells Fulltext Access 10 Pages 2006
Acidity constants in methanol/water mixtures of polycarboxylic acids used in drug salt preparations: Potentiometric determination of aqueous pKa values of quetiapine formulated as hemifumarate Fulltext Access 10 Pages 2006
Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases Fulltext Access 10 Pages 2006
Stabilization of solid dispersions of nimodipine and polyethylene glycol 2000 Fulltext Access 10 Pages 2006
Boosting support vector regression in QSAR studies of bioactivities of chemical compounds Fulltext Access 10 Pages 2006
A comparison of morphology and surface energy characteristics of sulfathiazole polymorphs based upon single particle studies Fulltext Access 10 Pages 2006
Bioavailability of seocalcitol: II: Development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides Fulltext Access 10 Pages 2006
Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particles Fulltext Access 10 Pages 2006
Relative bioavailability estimation of carbamazepine crystal forms using an artificial stomach-duodenum model Fulltext Access 10 Pages 2006
Cyclodextrins in the production of large porous particles: Development of dry powders for the sustained release of insulin to the lungs Fulltext Access 10 Pages 2006
Evaluation of the in vitro activity and in vivo bioavailability of realgar nanoparticles prepared by cryo-grinding Fulltext Access 10 Pages 2006
In situ gelling, bioadhesive nasal inserts for extended drug delivery: In vitro characterization of a new nasal dosage form Fulltext Access 10 Pages 2006
Transformation of vesicular into cubic nanoparticles by autoclaving of aqueous monoolein/poloxamer dispersions Fulltext Access 10 Pages 2006
In vivo tumor targeting of tumor necrosis factor-α-loaded stealth nanoparticles: Effect of MePEG molecular weight and particle size Fulltext Access 10 Pages 2006
Spray freezing into liquid versus spray-freeze drying: Influence of atomization on protein aggregation and biological activity Fulltext Access 10 Pages 2006
Novel transmucosal absorption enhancers obtained by aminoalkylation of chitosan Fulltext Access 10 Pages 2006
Electrostatic characterisation of inhaled powders: Effect of contact surface and relative humidity Fulltext Access 10 Pages 2006
Review of global regulations concerning biowaivers for immediate release solid oral dosage forms Fulltext Access 10 Pages 2006
Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system Fulltext Access 10 Pages 2006
Solubilization and dissolution of tamoxifenâhydroxybutenyl cyclodextrin complexes Fulltext Access 10 Pages 2006
Crystallization of sucrose glass under ambient conditions: Evaluation of crystallization rate and unusual melting behavior of resultant crystals Fulltext Access 10 Pages 2006
Evaluation of a vaporizing device (Volcano®) for the pulmonary administration of tetrahydrocannabinol Fulltext Access 10 Pages 2006
Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution-a validation study Fulltext Access 10 Pages 2006
Predicting the behavior of novel sugar carriers for dry powder inhaler formulations via the use of a cohesive-adhesive force balance approach Fulltext Access 10 Pages 2006
Differentiation and Quantitative Determination of Surface and Hydrate Water in Lyophilized Mannitol Using NIR Spectroscopy Fulltext Access 10 Pages 2006
Lipid and Electroosmosis Enhanced Transdermal Delivery of Insulin by Electroporation Fulltext Access 10 Pages 2006
In vitro percutaneous absorption and in vivo protoporphyrin IX accumulation in skin and tumors after topical 5-aminolevulinic acid application with enhancement using an erbium:YAG laser Fulltext Access 10 Pages 2006
Enhanced permeation of diazepam through artificial membranes from supersaturated solutions Fulltext Access 10 Pages 2006
Effect of cyclodextrins on α-chymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation Fulltext Access 10 Pages 2006
Increase of doxorubicin sensitivity for folate receptor positive cells when given as the prodrug Nâ(phenylacetyl) doxorubicin in combination with folateâconjugated PGA Fulltext Access 10 Pages 2006
Involvement of intracellular Ca2+ dynamics in cytoprotective action by amino acids and cytotoxicity by sodium laurate, an absorption enhancer Fulltext Access 10 Pages 2006
A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data Fulltext Access 10 Pages 2006
Microenvironmental pH Modulation Based Release Enhancement of a Weakly Basic Drug from Hydrophilic Matrices* Fulltext Access 10 Pages 2006
Prediction of Plasma Protein Binding Displacement and its Implications for Quantitative Assessment of Metabolic Drug-Drug Interactions from In Vitro Data Fulltext Access 10 Pages 2006
The use of colloid probe microscopy to predict aerosolization performance in dry powder inhalers: AFM and in vitro correlation Fulltext Access 10 Pages 2006
Understanding processing-induced phase transformations in erythromycin-PEG 6000 solid dispersions Fulltext Access 10 Pages 2006
Dose-Independent Pharmacokinetics of Metformin in Rats: Hepatic and Gastrointestinal First-Pass Effects Fulltext Access 10 Pages 2006
In Vivo Evaluation of a Nasal Insulin Delivery System Based on Thiolated Chitosan Fulltext Access 10 Pages 2006
Microscopic image analysis techniques for the morphological characterization of pharmaceutical particles: Influence of process variables Fulltext Access 10 Pages 2006
Carbopol-mediated paracellular transport enhancement in Calu-3 cell layers Fulltext Access 10 Pages 2006
Synthesis and in vitro antitumor activity of novel series 2-benzylthio-4-chlorobenzenesulfonamide derivatives Fulltext Access 10 Pages 2006
Ferrocene-containing cationic lipids for the delivery of DNA: Oxidation state determines transfection activity Fulltext Access 10 Pages 2006
Prophylactic anti-tumor effects in a B cell lymphoma model with DNA vaccines delivered on polyethylenimine (PEI) functionalized PLGA microparticles Fulltext Access 10 Pages 2006
Delivery of neurotrophin-3 from fibrin enhances neuronal fiber sprouting after spinal cord injury Fulltext Access 10 Pages 2006
A model for the drug release from a polymer matrix tablet—effects of swelling and dissolution Fulltext Access 10 Pages 2006
Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins Fulltext Access 10 Pages 2006
Stable cationic microparticles for enhanced model antigen delivery to dendritic cells Fulltext Access 10 Pages 2006
BCNU-loaded PEG–PLLA ultrafine fibers and their in vitro antitumor activity against Glioma C6 cells Fulltext Access 10 Pages 2006
Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents Fulltext Access 10 Pages 2006
Imaging the renin–angiotensin system: An important target of anti-hypertensive therapy Fulltext Access 10 Pages 2006
Synthesis and receptor binding studies of 3-substituted piperazine derivatives Fulltext Access 10 Pages 2006
Polar, functionalized guanine-O6 derivatives resistant to repair by O6-alkylguanine–DNA alkyltransferase: implications for the design of DNA-modifying drugs Fulltext Access 10 Pages 2006
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents Fulltext Access 10 Pages 2006
Synthesis of new hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives with an arylpiperazine moiety as ligands for 5-HT1A and 5-HT2A receptors. Part 4 Fulltext Access 10 Pages 2006
Synthesis, antibacterial activity and QSAR studies of 1,2-disubstituted-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines Fulltext Access 10 Pages 2006
3D-QSAR CoMFA study on indenopyrazole derivatives as cyclin dependent kinase 4 (CDK4) and cyclin dependent kinase 2 (CDK2) inhibitors Fulltext Access 10 Pages 2006
Synthesis and antitumor activity of cis-dichloroplatinum(II) complexes of 1-(2-aminophenyl)-1,2,3,4-tetrahydroisoquinolines Fulltext Access 10 Pages 2006
Synthesis, characterization and in vitro biological activity studies of Cu–M (M = Cu2+, Co2+, Ni2+, Mn2+, Zn2+) bimetallic complexes Fulltext Access 10 Pages 2006
Structure-based pharmacophore of COX-2 selective inhibitors and identification of original lead compounds from 3D database searching method Fulltext Access 10 Pages 2006
Synthesis and biological activity of some new 5′-O-acyl tiazofurin derivatives Fulltext Access 10 Pages 2006
Effects of N-trimethylchitosan on transcellular and paracellular transcorneal drug transport Fulltext Access 10 Pages 2006
Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase Fulltext Access 10 Pages 2006
Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying Fulltext Access 10 Pages 2006
The effect of solvent polarity on the accumulation of leachables from pharmaceutical product containers Fulltext Access 10 Pages 2006
Prediction of the pharmacokinetics of succinylated human serum albumin in man from in vivo disposition data in animals and in vitro liver slice incubations Fulltext Access 10 Pages 2006
Modification of the tri-phasic drug release pattern of leuprolide acetate-loaded poly(lactide-co-glycolide) microparticles Fulltext Access 10 Pages 2006
Versatility of biodegradable poly(d,l-lactic-co-glycolic acid) microspheres for plasmid DNA delivery Fulltext Access 10 Pages 2006
Fluorescence resonance energy transfer: Evaluation of the intracellular stability of polyplexes Fulltext Access 10 Pages 2006
Liquid crystalline phases of monoolein and water for topical delivery of cyclosporin A: Characterization and study of in vitro and in vivo delivery Fulltext Access 10 Pages 2006
Cefdinir: A comparative study of anhydrous vs. monohydrate form: Microstructure and tabletting behaviour Fulltext Access 10 Pages 2006
Skin permeation of different steroid hormones from polymeric coated liposomal formulations Fulltext Access 10 Pages 2006
Where disease pathogenesis meets protein formulation: Renal deposition of immunoglobulin aggregates Fulltext Access 10 Pages 2006
Enhancing mechanism of Labrasol on intestinal membrane permeability of the hydrophilic drug gentamicin sulfate Fulltext Access 10 Pages 2006
New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3D-QSAR (CoMFA) studies Fulltext Access 10 Pages 2006
On the role of methacrylic acid copolymers in the intracellular delivery of antisense oligonucleotides Fulltext Access 10 Pages 2006
Parameters affecting the drug release from in situ gelling nasal inserts Fulltext Access 10 Pages 2006
Water retention and drainage in different brands of microcrystalline cellulose: Effect of measuring conditions Fulltext Access 10 Pages 2006
Drug adsorption to plastic containers and retention of drugs in cultured cells under in vitro conditions Fulltext Access 10 Pages 2006
Visualizing the conversion of carbamazepine in aqueous suspension with and without the presence of excipients: A single crystal study using SEM and Raman microscopy Fulltext Access 10 Pages 2006
Impact of freezing procedure and annealing on the physico-chemical properties and the formation of mannitol hydrate in mannitol–sucrose–NaCl formulations Fulltext Access 10 Pages 2006
Copolymers of pharmaceutical grade lactic acid and sebacic acid: Drug release behavior and biocompatibility Fulltext Access 10 Pages 2006
The evolution of legislation to regulate pediatric clinical trials: Present and continuing challenges Fulltext Access 10 Pages 2006