Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans Fulltext Access 9 Pages 2005
Spirohydantoin derivatives of thiopyrano[2,3-b]pyridin-4(4H)-one as potent in vitro and in vivo aldose reductase inhibitors Fulltext Access 9 Pages 2005
Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates Fulltext Access 9 Pages 2005
Chalcones as potent tyrosinase inhibitors: the importance of a 2,4-substituted resorcinol moiety Fulltext Access 9 Pages 2005
Synthesis of imidazo[1,5,4-de]quinoxalin-9-ones, benzimidazole analogues of pyrroloiminoquinone marine natural products Fulltext Access 9 Pages 2005
Stereoselective synthesis, structural characterization, and properties of 1,2-O-isopropylidene-3-C-(5-phenyl-1,2,4-oxadiazol-3-yl)-β-d-psicopyranose Fulltext Access 9 Pages 2005
CP-MLR directed QSAR studies on the antimycobacterial activity of functionalized alkenols-topological descriptors in modeling the activity Fulltext Access 9 Pages 2005
Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding Fulltext Access 9 Pages 2005
Predicting stability of Arc repressor mutants with protein stochastic moments Fulltext Access 9 Pages 2005
Design, synthesis and photobiological properties of 3,4-cyclopentenepsoralens Fulltext Access 9 Pages 2005
Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter Fulltext Access 9 Pages 2005
Synthesis and in vivo biodistribution of BPA-Gd-DTPA complex as a potential MRI contrast carrier for neutron capture therapy Fulltext Access 9 Pages 2005
Biotin-phenyldiazomethane conjugates as labeling reagents at phosphate in mono and polynucleotides Fulltext Access 9 Pages 2005
The simultaneous determination of selected flavonol glycosides and aglycones in Ginkgo biloba oral dosage forms by high-performance liquid chromatography-electrospray ionisation-mass spectrometry Fulltext Access 9 Pages 2005
Simultaneous determination of metronidazole and spiramycin I in human plasma, saliva and gingival crevicular fluid by LC-MS/MS Fulltext Access 9 Pages 2005
Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography Fulltext Access 9 Pages 2005
Development and validation of a stability indicating HPLC method for determination of lisinopril, lisinopril degradation product and parabens in the lisinopril extemporaneous formulation Fulltext Access 9 Pages 2005
Development and validation of a high-performance liquid chromatography-mass spectrometry assay for methylxanthines and taurine in dietary supplements Fulltext Access 9 Pages 2005
Potentiometric flow injection analysis of mebeverine hydrochloride in serum and urine Fulltext Access 9 Pages 2005
The rutin/β-cyclodextrin interactions in fully aqueous solution: spectroscopic studies and biological assays Fulltext Access 9 Pages 2005
Application of surface ionization methods for highly sensitive and selective analysis of benzodiazepine derivatives Fulltext Access 9 Pages 2005
Molecular docking and 3D-QSAR studies of Yersinia protein tyrosine phosphatase YopH inhibitors Fulltext Access 9 Pages 2005
Redox-sensitive signaling factors as a novel molecular targets for cancer therapy Fulltext Access 9 Pages 2005
Production of vaccines against leading biowarfare toxins can utilize DNA scientific technology Fulltext Access 9 Pages 2005
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation Fulltext Access 9 Pages 2005
Pore formation in and enlargement of phospholipid liposomes by synthetic models of ceramides and sphingomyelin Fulltext Access 9 Pages 2005
QSAR studies on some thiophene analogs as anti-inflammatory agents: enhancement of activity by electronic parameters and its utilization for chemical lead optimization Fulltext Access 9 Pages 2005
Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers Fulltext Access 9 Pages 2005
Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues Fulltext Access 9 Pages 2005
Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin Fulltext Access 9 Pages 2005
Design and development of a fluorescent probe for monitoring hydrogen peroxide using photoinduced electron transfer Fulltext Access 9 Pages 2005
Use of chiral liquid chromatography for the evaluation of stereospecificity in the carbonyl reduction of potential benzo[c]fluorene antineoplastics benfluron and dimefluron in various species Fulltext Access 9 Pages 2005
Mechanistic study of proton transfer and hysteresis in catalytic antibody 16E7 by site-directed mutagenesis and homology modeling Fulltext Access 9 Pages 2005
Efficient fluorescent sensors of oligopeptides by dithiobis(2-benzoylamide)-bridged bis(β-cyclodextrin)s: structure in solution, binding behavior, and thermodynamic origin Fulltext Access 9 Pages 2005
Effect of Chinese medicine alpinetin on the structure of human serum albumin Fulltext Access 9 Pages 2005
Substituted propanolamines and alkylamines derived from fluoxetine as potent appetite suppressants Fulltext Access 9 Pages 2005
Design, synthesis, and biological evaluation of (E)- and (Z)-styryl-2-acetoxyphenyl sulfides and sulfones as cyclooxygenase-2 inhibitors Fulltext Access 9 Pages 2005
Comparative molecular field analysis and comparative molecular similarity indices analysis of human thymidine kinase 1 substrates Fulltext Access 9 Pages 2005
Novel thiocoumarins as inhibitors of TNF-α induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation Fulltext Access 9 Pages 2005
α-Glucopyranoimidazolines as intermediate analogue inhibitors of family 20 β-N-acetylglucosaminidases Fulltext Access 9 Pages 2005
Annelated pyrrolo-pyrimidines from amino-cyanopyrroles and BMMAs as leads for new DNA-interactive ring systems Fulltext Access 9 Pages 2005
Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents Fulltext Access 9 Pages 2005
Synthesis and evaluation of the antitrypanosomal and antiplasmodial activities of new 4-aminobicyclo[2.2.2]octane derivatives Fulltext Access 9 Pages 2005
The effect of powder blend and tablet structure on drug release mechanisms of hydrophobic starch acetate matrix tablets Fulltext Access 9 Pages 2005
Non-thiol farnesyltransferase inhibitors: N-(4-aminoacylamino-3-benzoylphenyl)-3-[5-(4-nitrophenyl)-2 furyl]acrylic acid amides and their antimalarial activity Fulltext Access 9 Pages 2005
Homology models of the cannabinoid CB1 and CB2 receptors. A docking analysis study Fulltext Access 9 Pages 2005
Non-imidazole histamine H3 ligands. Part III. New 4-n-propylpiperazines as non-imidazole histamine H3-antagonists Fulltext Access 9 Pages 2005
Estimation of the effect of the acidosis and alkalosis on the anesthetic potency of local anesthetics by biopartitioning micellar chromatography and micellar electrokinetic chromatography Fulltext Access 9 Pages 2005
Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine Fulltext Access 9 Pages 2005
Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2 Fulltext Access 9 Pages 2005
Synthesis and in vitro cytotoxic evaluation of 1,3-bisubstituted and 1,3,9-trisubstituted β-carboline derivatives Fulltext Access 9 Pages 2005
Benzenesulfonamide analogs of fluoroquinolones. Antibacterial activity and QSAR studies Fulltext Access 9 Pages 2005
Construction of a virtual combinatorial library using SMILES strings to discover potential structure-diverse PPAR modulators Fulltext Access 9 Pages 2005
Synthesis of 2-substituted β-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon Fulltext Access 9 Pages 2005
Silk fibroin as a novel coating material for controlled release of theophylline Fulltext Access 9 Pages 2005
Design, synthesis and bioactivities of TAR RNA targeting β-carboline derivatives based on Tat-TAR interaction Fulltext Access 9 Pages 2005
Structure-activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor Fulltext Access 9 Pages 2005
Design, synthesis and biological activity of acyl substituted 3-amino-5-methyl-1,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones as potential hypnotic drugs Fulltext Access 9 Pages 2005
AMBER force field implementation of the boronate function to simulate the inhibition of β-lactamases by alkyl and aryl boronic acids Fulltext Access 9 Pages 2005
Synthesis of 2,5- and 3,5-diphenylpyridine derivatives for DNA recognition and cytotoxicity Fulltext Access 9 Pages 2005
Novel milrinone analogs of pyridine-3-carbonitrile derivatives as promising cardiotonic agents Fulltext Access 9 Pages 2005
A new potential cyclooxygenase-2 inhibitor, pyridinic analogue of nimesulide Fulltext Access 9 Pages 2005
Synthesis and biological evaluation of functionalized coumarins as acetylcholinesterase inhibitors Fulltext Access 9 Pages 2005
Structural changes of benzylether derivatives of vesamicol and their influence on the binding selectivity to the vesicular acetylcholine transporter Fulltext Access 9 Pages 2005
Docking studies on monoamine oxidase-B inhibitors: Estimation of inhibition constants (Ki) of a series of experimentally tested compounds Fulltext Access 9 Pages 2005
Studies of drug binding to plasma proteins using a variant of equilibrium dialysis Fulltext Access 9 Pages 2005
Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatography Fulltext Access 9 Pages 2005
Evaluation of basic algorithms for transferring quantitative multivariate calibrations between scanning grating and FT NIR spectrometers Fulltext Access 9 Pages 2005
A comparison of methods for alignment of NMR peaks in the context of cluster analysis Fulltext Access 9 Pages 2005
Minimization of ion suppression in LC-MS/MS analysis through the application of strong cation exchange solid-phase extraction (SCX-SPE) Fulltext Access 9 Pages 2005
Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts Fulltext Access 9 Pages 2005
Simultaneously measuring concentrations of a model drug and a model excipient in solution using ultrasonic spectrometry Fulltext Access 9 Pages 2005
Determination of the molecular complexation constant between alprostadil and alpha-cyclodextrin by conductometry Fulltext Access 9 Pages 2005
Platelet-derived growth factor receptor (PDGFR): A target for anticancer therapeutics Fulltext Access 9 Pages 2005
The interaction between carrier rugosity and carrier payload, and its effect on drug particle redispersion from adhesive mixtures during inhalation Fulltext Access 9 Pages 2005
Applying pattern recognition methods and structure property correlations to determine drug carrier potential of nicotinic acid and analogize to dihydropyridine Fulltext Access 9 Pages 2005
Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors Fulltext Access 9 Pages 2005
Formulation development of inhalation powders for FK888 using the E-haler® to improve the inhalation performance at a high dose, and its absorption in healthy volunteers Fulltext Access 9 Pages 2005
Understanding agglomeration of indomethacin during the dissolution of micronised indomethacin mixtures through dissolution and de-agglomeration modeling approaches Fulltext Access 9 Pages 2005
Application of an electronic nose system for evaluation of unpleasant odor in coated tablets Fulltext Access 9 Pages 2005
Development of an enteric-coated pellet formulation of F4 fimbriae for oral vaccination of suckling piglets against enterotoxigenic Escherichia coli infections Fulltext Access 9 Pages 2005
Effects of process variables on the powder yield of spray-dried trehalose on a laboratory spray-dryer Fulltext Access 9 Pages 2005
A comparison between povidone-ethylcellulose and povidone-eudragit transdermal dexamethasone matrix patches based on in vitro skin permeation Fulltext Access 9 Pages 2005
Manufacturing, regulatory and commercial challenges of biopharmaceuticals production: a Finnish perspective Fulltext Access 9 Pages 2005
Synthesis and characterisation of novel nanospheres made from amphiphilic perfluoroalkylthio-β-cyclodextrins Fulltext Access 9 Pages 2005
Comparison of powder produced by evaporative precipitation into aqueous solution (EPAS) and spray freezing into liquid (SFL) technologies using novel Z-contrast STEM and complimentary techniques Fulltext Access 9 Pages 2005
Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy Fulltext Access 9 Pages 2005
Molecular weights of poly(butyl cyanoacrylate) nanoparticles determined by mass spectrometry and size exclusion chromatography Fulltext Access 9 Pages 2005