Development, validation, and implementation of a multiplex immunoassay for the simultaneous determination of five cytokines in human serum Fulltext Access 8 Pages 2005
Binding of β-d-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies Fulltext Access 8 Pages 2005
Synthesis and structure-activity relationships of 6-{4-[(3-fluorobenzyl)oxy]phenoxy}nicotinamide derivatives as a novel class of NCX inhibitors: a QSAR study Fulltext Access 8 Pages 2005
A radial distribution function approach to predict A2B agonist effect of adenosine analogues Fulltext Access 8 Pages 2005
Analysis of essential elements in Pragya-peya-a herbal drink and its constituents by neutron activation Fulltext Access 8 Pages 2005
Assay validation for three antidepressants in pharmaceutical formulations: Practical approach using capillary gas chromatography Fulltext Access 8 Pages 2005
The influence of Calendulae officinalis flos extracts on cell cultures, and the chromatographic analysis of extracts Fulltext Access 8 Pages 2005
A validated HPLC method for determining residues of a dual active ingredient anti-malarial drug on manufacturing equipment surfaces Fulltext Access 8 Pages 2005
A validated chiral LC method for the determination of Zolmitriptan and its potential impurities Fulltext Access 8 Pages 2005
Fast analysis of glycosaminoglycans by microchip electrophoresis with in situ fluorescent detection using ethidium bromide Fulltext Access 8 Pages 2005
Simultaneous determination of niacin, niacinamide and nicotinuric acid in human plasma Fulltext Access 8 Pages 2005
Development and validation of HPLC methods for the enantioselective analysis of bambuterol and albuterol Fulltext Access 8 Pages 2005
Development and validation of a fully automated LC method for the determination of cloxacillin in human plasma using anion exchange restricted access material for sample clean-up Fulltext Access 8 Pages 2005
Integrated on-line sample clean-up using cation exchange restricted access sorbent for the LC determination of atropine in human plasma coupled to UV detection Fulltext Access 8 Pages 2005
A rapid and simple procedure for the determination of cannabinoids in hemp food products by gas chromatography-mass spectrometry Fulltext Access 8 Pages 2005
Development and validation of a bioanalytical method using automated solid-phase extraction and LC-UV for the simultaneous determination of lumefantrine and its desbutyl metabolite in plasma Fulltext Access 8 Pages 2005
A selective and rapid method for the quantification of captopril in human plasma using liquid chromatography/selected reaction monitoring mass spectrometry Fulltext Access 8 Pages 2005
Screening of anabolic steroids in horse urine by liquid chromatography-tandem mass spectrometry Fulltext Access 8 Pages 2005
Determination of stability constant values of flurbiprofen-cyclodextrin complexes using different techniques Fulltext Access 8 Pages 2005
Interaction of naproxen with ionic cyclodextrins in aqueous solution and in the solid state Fulltext Access 8 Pages 2005
Analytical method for appreciation of garlic therapeutic potential and for validation of a new formulation Fulltext Access 8 Pages 2005
Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles Fulltext Access 8 Pages 2005
Identification and characterization of nonsubstrate based inhibitors of the essential dengue and West Nile virus proteases Fulltext Access 8 Pages 2005
New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides Fulltext Access 8 Pages 2005
Synthesis and photodynamic activity of zinc(II) phthalocyanine derivatives bearing methoxy and trifluoromethylbenzyloxy substituents in homogeneous and biological media Fulltext Access 8 Pages 2005
Classical and three-dimensional QSAR for the inhibition of [3H]ponasterone A binding by diacylhydrazine-type ecdysone agonists to insect Sf-9 cells Fulltext Access 8 Pages 2005
Formylchromone derivatives as irreversible and selective inhibitors of human protein tyrosine phosphatase 1B. Kinetic and modeling studies Fulltext Access 8 Pages 2005
NMR conformational analysis of p-tolyl furanopyrimidine 2â²-deoxyribonucleoside and crystal structure of its 3â²,5â²-di-O-acetyl derivative Fulltext Access 8 Pages 2005
Nγ-Aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site Fulltext Access 8 Pages 2005
Inhibition of classical pathway of complement activation with negative charged derivatives of bisphenol A and bisphenol disulphates Fulltext Access 8 Pages 2005
Effects of 8-methyl-2â²-deoxyadenosine incorporation into quadruplex forming oligodeoxyribonucleotides Fulltext Access 8 Pages 2005
Spectrometric studies of cytotoxic protoberberine alkaloids binding to double-stranded DNA Fulltext Access 8 Pages 2005
Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis Fulltext Access 8 Pages 2005
Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoromethoxy-d2-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor Fulltext Access 8 Pages 2005
Synthesis and cellular studies of an octa-anionic 5,10,15,20-tetra[3,5-(nido-carboranylmethyl)phenyl]porphyrin (H2OCP) for application in BNCT Fulltext Access 8 Pages 2005
Thio-heterocylic naphthalimides with aminoalkyl side chains: novel alternative tools for photodegradation of genomic DNA without impairment on bioactivities of proteins Fulltext Access 8 Pages 2005
Synthesis and biodistribution of [11C]R116301, a promising PET ligand for central NK1 receptors Fulltext Access 8 Pages 2005
Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cells Fulltext Access 8 Pages 2005
3D QSAR Markov model for drug-induced eosinophilia-theoretical prediction and preliminary experimental assay of the antimicrobial drug G1 Fulltext Access 8 Pages 2005
Synthesis and hybridization properties of the conjugates of oligonucleotides and stabilization agents. Part 3 Fulltext Access 8 Pages 2005
Quantitative structure and aldose reductase inhibitory activity relationship of 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3â²-pyrrolidine-1,2â²,3,5â²-tetrone derivatives Fulltext Access 8 Pages 2005
Synthesis of 2-amino-6-(4-[11C]methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) ester as a novel potential PET gene reporter probe for HBV and HSV-tk in cancers Fulltext Access 8 Pages 2005
Structure-activity relationship study on 13-deoxytedanolide, a highly antitumor macrolide from the marine sponge Mycale adhaerens Fulltext Access 8 Pages 2005
Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate Fulltext Access 8 Pages 2005
Design and synthesis of (Z)-1,2-diphenyl-1-(4-methanesulfonamidophenyl)alk-1-enes and (Z)-1-(4-azidophenyl)-1,2-diphenylalk-1-enes: novel inhibitors of cyclooxygenase-2 (COX-2) with anti-inflammatory and analgesic activity Fulltext Access 8 Pages 2005
Functional studies on a ketoreductase gene from Streptomyces sp. AM-7161 to control the stereochemistry in medermycin biosynthesis Fulltext Access 8 Pages 2005
Identification and characterization of small molecule modulators of KChIP/Kv4 function Fulltext Access 8 Pages 2005
Organic synthesis in pursuit of immunology: Large-scale synthesis of peracetylated GM2 glycosylamino acid for preparation of a multiantigenic prostate cancer vaccine Fulltext Access 8 Pages 2005
The solution structure of a lasalocid A metal complex in lipophilic solvents Fulltext Access 8 Pages 2005
Theoretical simulation of the electronic circular dichroism spectrum of calicheamicin Fulltext Access 8 Pages 2005
New reagents for phosphatidylserine recognition and detection of apoptosis Fulltext Access 8 Pages 2005
Synthesis of chromenochalcones and evaluation of their in vitro antileishmanial activity Fulltext Access 8 Pages 2005
Synthesis of some monocyclic analogues of mycophenolic acid via the Johnson ortho ester Claisen rearrangement Fulltext Access 8 Pages 2005
Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives Fulltext Access 8 Pages 2005
Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile Fulltext Access 8 Pages 2005
Oxidation of liposomal membrane suppressed by flavonoids: Quantitative structure-activity relationship Fulltext Access 8 Pages 2005
‘O-Acyl isopeptide method’ for the efficient preparation of amyloid β peptide 1–42 mutants Fulltext Access 8 Pages 2005
Design and synthesis of N-benzylpiperidine–purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase Fulltext Access 8 Pages 2005
Tetra substituted thiophenes as anti-inflammatory agents: Exploitation of analogue-based drug design Fulltext Access 8 Pages 2005
Synthesis and characterization of azole isoflavone inhibitors of aromatase Fulltext Access 8 Pages 2005
Napthalimidobenzamide DB-51630: a novel DNA binding agent inducing p300 gene expression and exerting a potent anti-cancer activity Fulltext Access 8 Pages 2005
Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA Fulltext Access 8 Pages 2005
Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation Fulltext Access 8 Pages 2005
New ether diglycosides from Matayba guianensis with antiplasmodial activity Fulltext Access 8 Pages 2005
Chemical regulation of abscisic acid catabolism in plants by cytochrome P450 inhibitors Fulltext Access 8 Pages 2005
Inhibitory effects of flavonol glycosides from Cinnamomum osmophloeum on inflammatory mediators in LPS/IFN-γ-activated murine macrophages Fulltext Access 8 Pages 2005
High-performance liquid chromatographic determination of ciprofloxacin in plasma samples Fulltext Access 8 Pages 2005
Fluorescence spectroscopic study of serum albumin-bromadiolone interaction: fluorimetric determination of bromadiolone Fulltext Access 8 Pages 2005
Assay of the anti-psychotic drug haloperidol in bulk form, pharmaceutical formulation and biological fluids using square-wave adsorptive stripping voltammetry at a mercury electrode Fulltext Access 8 Pages 2005
4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity Fulltext Access 8 Pages 2005
QSAR study on thiazole and thiadiazole analogues as antagonists for the adenosine A1 and A3 receptors Fulltext Access 8 Pages 2005
Synthesis and evaluation of the permeability transition inhibitory characteristics of paramagnetic and diamagnetic amiodarone derivatives Fulltext Access 8 Pages 2005
Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachiadenus longiflorus Griseb. (Gentianaceae) Fulltext Access 8 Pages 2005
Syntheses of quinolone hydrochloride enantiomers from synthons (R)- and (S)-2-methylpiperazine Fulltext Access 8 Pages 2005
Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic Fulltext Access 8 Pages 2005
Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms Fulltext Access 8 Pages 2005
A new polyamine derivative, a structural analog of spermine, with in vivo activity as an inhibitor of ethanol appetite Fulltext Access 8 Pages 2005
Copper-metalated peptide palindrome derived from prion octarepeat: synthesis, aggregation, and oxidative transformations Fulltext Access 8 Pages 2005
Synthesis and evaluation of bifunctional chelating agents derived from bis(2-aminophenylthio)alkane for radioimaging with 99mTc Fulltext Access 8 Pages 2005
Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 4: 3-Alkyl-4-halo-6-nitroquipazines Fulltext Access 8 Pages 2005
Efficient synthesis of fluorothiosparfosic acid analogues with potential antitumoral activity Fulltext Access 8 Pages 2005
Comparison of positively charged DNG with DNA duplexes: a computational approach Fulltext Access 8 Pages 2005
Synthesis and preliminary biological evaluation of O6-[4-(2-[18F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in cancer chemotherapy Fulltext Access 8 Pages 2005
Synthesis and pharmacological activities of some mononuclear Ru(II) complexes Fulltext Access 8 Pages 2005
Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: Further evidence for the existence of an abnormal pathway for heme biosynthesis Fulltext Access 8 Pages 2005
Synthesis and biological evaluation of new 4β-anilino- and 4β-imido-substituted podophyllotoxin congeners Fulltext Access 8 Pages 2005