Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy Fulltext Access 8 Pages 2015
Buccal mucosal delivery of a potent peptide leads to therapeutically-relevant plasma concentrations for the treatment of autoimmune diseases Fulltext Access 8 Pages 2015
Applicability and safety of dual-frequency ultrasonic treatment for the transdermal delivery of drugs Fulltext Access 8 Pages 2015
Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity Fulltext Access 8 Pages 2015
Impact insertion of transfer-molded microneedle for localized and minimally invasive ocular drug delivery Fulltext Access 8 Pages 2015
Pulmonary administration of phosphoinositide 3-kinase inhibitor is a curative treatment for chronic obstructive pulmonary disease by alveolar regeneration Fulltext Access 8 Pages 2015
Remote spatiotemporally controlled and biologically selective permeabilization of blood-brain barrier Fulltext Access 8 Pages 2015
Development and validation of liquid chromatography tandem mass spectrometry method for simultaneous quantification of first line tuberculosis drugs and metabolites in human plasma and its application in clinical study Fulltext Access 8 Pages 2015
A method to quantitate the neutralizing capacity of anti-therapeutic protein antibodies in serum and their correlation to clinical impact Fulltext Access 8 Pages 2015
Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry Fulltext Access 8 Pages 2015
High-performance liquid chromatography method for the determination of hydrogen peroxide present or released in teeth bleaching kits and hair cosmetic products Fulltext Access 8 Pages 2015
Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation Fulltext Access 8 Pages 2015
Analytical approach for the determination of steroid profile of humans by gas chromatography isotope ratio mass spectrometry aimed at distinguishing between endogenous and exogenous steroids Fulltext Access 8 Pages 2015
Application of vibrational spectroscopy, thermal analyses and X-ray diffraction in the rapid evaluation of the stability in solid-state of ranitidine, famotidine and cimetidine Fulltext Access 8 Pages 2015
A novel, simple and inexpensive procedure for the simultaneous determination of iopamidol and p-aminohippuric acid for renal function assessment from plasma samples in awake rats Fulltext Access 8 Pages 2015
Prioritization and analysis of pharmaceuticals for human use contaminating the aquatic ecosystem in Italy Fulltext Access 8 Pages 2015
Simultaneous quantitative determination of celecoxib and its two metabolites using liquid chromatography-tandem mass spectrometry in alternating polarity switching mode Fulltext Access 8 Pages 2015
Development of a nucleotide sugar purification method using a mixed mode column & mass spectrometry detection Fulltext Access 8 Pages 2015
Dose-dependent targeted knockout methodology combined with deep structure elucidation strategies for Chinese licorice chemical profiling Fulltext Access 8 Pages 2015
Liquid crystalline phase as a probe for crystal engineering of lactose: Carrier for pulmonary drug delivery Fulltext Access 8 Pages 2015
Application of physiologically based pharmacokinetic modeling in the prediction of pharmacokinetics of bicyclol controlled-release formulation in human Fulltext Access 8 Pages 2015
Comparative effect of gold nanorods and nanocages for prostate tumor hyperthermia Fulltext Access 8 Pages 2015
Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural administration of liposomal pemetrexed Fulltext Access 8 Pages 2015
Synthesis of potent urease inhibitors based on disulfide scaffold and their molecular docking studies Fulltext Access 8 Pages 2015
Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries Fulltext Access 8 Pages 2015
Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity Fulltext Access 8 Pages 2015
Norbornane-based nucleoside and nucleotide analogues locked in North conformation Fulltext Access 8 Pages 2015
Discovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents Fulltext Access 8 Pages 2015
Synthesis of novel 10-hydroxycamptothecin derivatives utilizing topotecan hydrochloride as ortho-quinonemethide precursor Fulltext Access 8 Pages 2015
Chemoenzymatic synthesis and cytotoxicity of oenanthotoxin and analogues Fulltext Access 8 Pages 2015
Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity Fulltext Access 8 Pages 2015
Controlled release of acidic drugs in compendial and physiological hydrogen carbonate buffer from polymer blend-coated oral solid dosage forms Fulltext Access 8 Pages 2015
Rational design, synthesis and structure-activity relationships of 4-alkoxy- and 4-acyloxy-phenylethylenethiosemicarbazone analogues as novel tyrosinase inhibitors Fulltext Access 8 Pages 2015
Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation Fulltext Access 8 Pages 2015
Selective induction of oxidative stress in cancer cells via synergistic combinations of agents targeting redox homeostasis Fulltext Access 8 Pages 2015
The influence of residual water on the solid-state properties of freeze-dried fibrinogen Fulltext Access 8 Pages 2015
Targeted therapy of colorectal neoplasia with rapamycin in peptide-labeled pegylated octadecyl lithocholate micelles Fulltext Access 8 Pages 2015
A polymeric conjugate foreignizing tumor cells for targeted immunotherapy in vivo Fulltext Access 8 Pages 2015
Endothelium and cancer metastasis: Perspectives for antimetastatic therapy Fulltext Access 8 Pages 2015
Pinocembrin attenuates hippocampal inflammation, oxidative perturbations and apoptosis in a rat model of global cerebral ischemia reperfusion Fulltext Access 8 Pages 2015
Multifactorial effects of vildagliptin added to ongoing metformin therapy in patients with type 2 diabetes mellitus Fulltext Access 8 Pages 2015
Methylphenidate increases glucose uptake in the brain of young and adult rats Fulltext Access 8 Pages 2015
Anti-hypernociceptive and anti-oxidative effects of locally treated dobutamine in diabetic rats Fulltext Access 8 Pages 2015
Immunohistochemical, apoptotic and biochemical changes by dipeptidyl peptidase-4 inhibitor-sitagliptin in type-2 diabetic rats Fulltext Access 8 Pages 2015
Synthesis and broad-spectrum antiproliferative activity of diarylamides and diarylureas possessing 1,3,4-oxadiazole derivatives Fulltext Access 8 Pages 2015
Design, synthesis and evaluation of benzotriazole derivatives as novel antifungal agents Fulltext Access 8 Pages 2015
Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space Fulltext Access 8 Pages 2015
Antiproliferative activity of synthetic fatty acid amides from renewable resources Fulltext Access 8 Pages 2015
Synthesis of dansyl-labeled probe of thiophene analogue of annonaceous acetogenins for visualization of cell distribution and growth inhibitory activity toward human cancer cell lines Fulltext Access 8 Pages 2015
Skin microvascular endothelial function as a biomarker in cardiovascular diseases? Fulltext Access 8 Pages 2015
Development of a time-resolved fluorescence probe for evaluation of competitive binding to the cholecystokinin 2 receptor Fulltext Access 8 Pages 2015
Synthesis and antiviral activity of maleopimaric and quinopimaric acids’ derivatives Fulltext Access 8 Pages 2015
Design, synthesis and biological evaluation of a highly-potent and cancer cell selective folate–taxoid conjugate Fulltext Access 8 Pages 2015
Discovery of novel pyrazolopyrimidinone analogs as potent inhibitors of phosphodiesterase type-5 Fulltext Access 8 Pages 2015
Design, synthesis and antibacterial study of new potent and selective coumarin–chalcone derivatives for the treatment of tenacibaculosis Fulltext Access 8 Pages 2015
Ring substitution influences oxidative cyclisation and reactive metabolite formation of nordihydroguaiaretic acid analogues Fulltext Access 8 Pages 2015
Stereospecific inhibition of nitric oxide production in macrophage cells by flavanonols: Synthesis and the structure–activity relationship Fulltext Access 8 Pages 2015
Synthesis of fucosylated lacto-N-tetraose using whole-cell biotransformation Fulltext Access 8 Pages 2015
High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry Fulltext Access 8 Pages 2015
Helical peptide–polyamine and –polyether conjugates as synthetic ionophores Fulltext Access 8 Pages 2015
A comparative study between conventional pan coater and quasi-continuous small batch coater on the stability of tablets containing acetylsalicylic acid Fulltext Access 8 Pages 2015
Novel nanosized formulations of two diclofenac acid polymorphs to improve topical bioavailability Fulltext Access 8 Pages 2015
Monitoring of mycophenolate mofetil metabolites in children with nephrotic syndrome and the proposed novel target values of pharmacokinetic parameters Fulltext Access 8 Pages 2015
Quality improvement of melt extruded laminar systems using mixture design Fulltext Access 8 Pages 2015
Development of omega-3 phospholipid-based solid dispersion of fenofibrate for the enhancement of oral bioavailability Fulltext Access 8 Pages 2015
Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide Fulltext Access 8 Pages 2015
Naturally occurring didemnaketals: Structural elucidation, features, and pharmacological activities Fulltext Access 8 Pages 2015
Synthesis and anti-mycobacterial evaluation of some new isonicotinylhydrazide analogues Fulltext Access 8 Pages 2015
Effects of antibiotic antitumor drugs on nucleotide levels in cultured tumor cells: an exploratory method to distinguish the mechanisms of antitumor drug action based on targeted metabolomics Fulltext Access 8 Pages 2015
Defining the frontiers between antifungal resistance, tolerance and the concept of persistence Fulltext Access 8 Pages 2015
Development of sustained and dual drug release co-extrusion formulations for individual dosing Fulltext Access 8 Pages 2015
Arginine-tagging of polymeric nanoparticles via histidine to improve cellular uptake Fulltext Access 8 Pages 2015
Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation Fulltext Access 8 Pages 2015
Mucoadhesive cellulosic derivative sponges as drug delivery system for vaginal application Fulltext Access 8 Pages 2015
Chitosan based micro- and nanoparticles for colon-targeted delivery of vancomycin prepared by alternative processing methods Fulltext Access 8 Pages 2015
From silk spinning in insects and spiders to advanced silk fibroin drug delivery systems Fulltext Access 8 Pages 2015
External physical and biochemical stimulation to enhance skeletal muscle bioengineering Fulltext Access 8 Pages 2015
Regenerative medicine for the treatment of reproductive system disorders: Current and potential options Fulltext Access 8 Pages 2015
Tissue engineered buccal mucosa for urethroplasty: Progress and future directions Fulltext Access 8 Pages 2015
Neuroprotective effect of noscapine on cerebral oxygen–glucose deprivation injury Fulltext Access 8 Pages 2015
Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy Fulltext Access 8 Pages 2015