Improving Monoclonal Antibody Selection and Engineering using Measurements of Colloidal Protein Interactions Fulltext Access 8 Pages 2014
Probing Location of Anti-TB Drugs Loaded in Brij 96 Microemulsions Using Thermoanalytical and Photophysical Approach Fulltext Access 8 Pages 2014
Control of Protein Particle Formation During Ultrafiltration/Diafiltration Through Interfacial Protection Fulltext Access 8 Pages 2014
Effect of Added Alkalizer and Surfactant on Dissolution and Absorption of the Potassium Salt of a Weakly Basic Poorly Water-Soluble Drug Fulltext Access 8 Pages 2014
What Is the Mechanism Behind Increased Permeation Rate of a Poorly Soluble Drug from Aqueous Dispersions of an Amorphous Solid Dispersion? Fulltext Access 8 Pages 2014
Significance of Metabolites in Bioequivalence: Losartan Potassium as a Case Study Fulltext Access 8 Pages 2014
Lysozyme-Triggered Epidermal Growth Factor Release from Bacterial Cellulose Membranes Controlled by Smart Nanostructured Films Fulltext Access 8 Pages 2014
Effect of Heating Rate and Kinetic Model Selection on Activation Energy of Nonisothermal Crystallization of Amorphous Felodipine Fulltext Access 8 Pages 2014
Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin Fulltext Access 8 Pages 2014
Kinetics and Mechanism of the Base-Catalyzed Rearrangement and Hydrolysis of Ezetimibe Fulltext Access 8 Pages 2014
The Use of Supersaturation for the Vaginal Application of Microbicides: A Case Study with Dapivirine Fulltext Access 8 Pages 2014
Substituent Effect on the Thermodynamic Solubility of Structural Analogs: Relative Contribution of Crystal Packing and Hydration Fulltext Access 8 Pages 2014
Hexyl Glucoside and Hexyl Maltoside Inhibit Light-Induced Oxidation of Tryptophan Fulltext Access 8 Pages 2014
Transporter assays and assay ontologies: useful tools for drug discovery Fulltext Access 8 Pages 2014
Endocannabinoid signaling in hypothalamic-pituitary-adrenocortical axis recovery following stress: Effects of indirect agonists and comparison of male and female mice Fulltext Access 8 Pages 2014
Excitatory/inhibitory equilibrium of the central amygdala nucleus gates anti-depressive and anxiolytic states in the hamster Fulltext Access 8 Pages 2014
Effects of combining tactile with visual and spatial cues in conditioned place preference Fulltext Access 8 Pages 2014
Evaluation of the association between blood homocysteine concentration and the degree of behavioral symptoms in the 6-hydroxydopamine-induced Parkinsonism in rat Fulltext Access 8 Pages 2014
High-dose corticosterone after fear conditioning selectively suppresses fear renewal by reducing anxiety-like response Fulltext Access 8 Pages 2014
Guanosine prevents behavioral alterations in the forced swimming test and hippocampal oxidative damage induced by acute restraint stress Fulltext Access 8 Pages 2014
Behavior of knock-in mice with a cocaine-insensitive dopamine transporter after virogenetic restoration of cocaine sensitivity in the striatum Fulltext Access 8 Pages 2014
Is bisphosphonate therapy compromised by the emergence of adverse bone disorders? Fulltext Access 8 Pages 2014
Deciphering molecular determinants of chemotherapy in gastrointestinal malignancy using systems biology approaches Fulltext Access 8 Pages 2014
Improvement of preclinical animal models for autoimmune-mediated disorders via reverse translation of failed therapies Fulltext Access 8 Pages 2014
Physicochemical modifications of histones and their impact on epigenomics Fulltext Access 8 Pages 2014
Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: a psoriasis case study Fulltext Access 8 Pages 2014
Selective targets for arousal-modifying drugs: implications for the treatment of sleep disorders Fulltext Access 8 Pages 2014
Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines Fulltext Access 8 Pages 2014
Drug name recognition in biomedical texts: a machine-learning-based method Fulltext Access 8 Pages 2014
Binucleation of cardiomyocytes: the transition from a proliferative to a terminally differentiated state Fulltext Access 8 Pages 2014
Pharmacological treatment of chronic obstructive pulmonary disease: from evidence-based medicine to phenotyping Fulltext Access 8 Pages 2014
Virtual pharmaceutical companies: collaborating flexibly in pharmaceutical development Fulltext Access 8 Pages 2014
Influence of ghrelin on the central serotonergic signaling system in mice Fulltext Access 8 Pages 2014
Modelling three-dimensional protein structures for applications in drug design Fulltext Access 8 Pages 2014
A case study: semantic integration of gene-disease associations for type 2 diabetes mellitus from literature and biomedical data resources Fulltext Access 8 Pages 2014
Cellular and molecular mechanisms of bone damage and repair in inflammatory arthritis Fulltext Access 8 Pages 2014
Exploratory toxicology as an integrated part of drug discovery. Part II: Screening strategies Fulltext Access 8 Pages 2014
Pharmacokinetics in Rats of a Long-Acting Human Parathyroid Hormone-Collagen Binding Domain Peptide Construct Fulltext Access 8 Pages 2014
Glucosamine Dose/Concentration-Effect Correlation in the Rat with Adjuvant Arthritis Fulltext Access 8 Pages 2014
Equilibrium Gel Filtration to Measure Plasma Protein Binding of Very Highly Bound Drugs Fulltext Access 8 Pages 2014
Improved Permeability of Acyclovir: Optimization of Mucoadhesive Liposomes Using the Phospholipid Vesicle-Based Permeation Assay Fulltext Access 8 Pages 2014
Nose-to-Brain Delivery: Evaluation of Polymeric Nanoparticles on Olfactory Ensheathing Cells Uptake Fulltext Access 8 Pages 2014
Adolescent traumatic stress experience results in less robust conditioned fear and post-extinction fear cue responses in adult rats Fulltext Access 8 Pages 2014
Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications Fulltext Access 8 Pages 2014
In vitro models of the metastatic cascade: from local invasion to extravasation Fulltext Access 8 Pages 2014
A mouse model mimicking human first night effect for the evaluation of hypnotics Fulltext Access 8 Pages 2014
Dietary-induced binge eating increases prefrontal cortex neural activation to restraint stress and increases binge food consumption following chronic guanfacine Fulltext Access 8 Pages 2014
Genetic influences on response to alcohol and response to pharmacotherapies for alcoholism Fulltext Access 8 Pages 2014
Evaluation of the potential of antipsychotic agents to induce catalepsy in rats: Assessment of a new, commercially available, semi-automated instrument Fulltext Access 8 Pages 2014
Understanding the anti-kindling role and its mechanism of Resveratrol in Pentylenetetrazole induced-kindling in a rat model Fulltext Access 8 Pages 2014
The reinforcing and subjective effects of intravenous and intranasal buprenorphine in heroin users Fulltext Access 8 Pages 2014
Activities of 2-phthalimidethanol and 2-phthalimidethyl nitrate, phthalimide analogs devoid of the glutarimide moiety, in experimental models of inflammatory pain and edema Fulltext Access 8 Pages 2014
Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice Fulltext Access 8 Pages 2014
Acute intraperitoneal injection of caffeine improves endurance exercise performance in association with increasing brain dopamine release during exercise Fulltext Access 8 Pages 2014
Antidepressant-related sexual dysfunction — Perspectives from neuroimaging Fulltext Access 8 Pages 2014
Opioid modulation of prolactin secretion induced by stress during late pregnancy. Role of ovarian steroids Fulltext Access 8 Pages 2014
Modulation of adenosinergic system and its application for the treatment of epilepsy Fulltext Access 8 Pages 2014
The endocannabinoid anandamide regulates the peristaltic reflex by reducing neuro-neuronal and neuro-muscular neurotransmission in ascending myenteric reflex pathways in rats Fulltext Access 8 Pages 2014
Exogenous hydrogen sulfide causes different hemodynamic effects in normotensive and hypertensive rats via neurogenic mechanisms Fulltext Access 8 Pages 2014
The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke Fulltext Access 8 Pages 2014
Immunosuppression does not affect human bone marrow mesenchymal stromal cell efficacy after transplantation in traumatized mice brain Fulltext Access 8 Pages 2014
High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response Fulltext Access 8 Pages 2014
Imaging opioid analgesia in the human brain and its potential relevance for understanding opioid use in chronic pain Fulltext Access 8 Pages 2014
Opioid receptors in the prelimbic cortex modulate restraint stress-induced cardiovascular responses in the rat Fulltext Access 8 Pages 2014
Ciproxifan improves working memory through increased prefrontal cortex neural activity in sleep-restricted mice Fulltext Access 8 Pages 2014
Glutamatergic mechanisms associated with stress-induced amygdala excitability and anxiety-related behavior Fulltext Access 8 Pages 2014
Invited reviewAlcohol: A stimulant activating brain stress responsive systems with persistent neuroadaptation Fulltext Access 8 Pages 2014
Lycopene attenuates insulin signaling deficits, oxidative stress, neuroinflammation, and cognitive impairment in fructose-drinking insulin resistant rats Fulltext Access 8 Pages 2014
Integrated workflow for quantitative phosphoproteomic analysis of the selected brain structures in development of morphine dependence Fulltext Access 8 Pages 2014
Targeting histone-modifications in Alzheimer's disease. What is the evidence that this is a promising therapeutic avenue? Fulltext Access 8 Pages 2014
Decoding transcriptional repressor complexes in the adult central nervous system Fulltext Access 8 Pages 2014
Phenytoin attenuates the hyper-exciting neurotransmission in cultured embryonic cortical neurons Fulltext Access 8 Pages 2014
Bradykinin postconditioning ameliorates focal cerebral ischemia in the rat Fulltext Access 8 Pages 2014
Expression of transcribed ultraconserved regions of genome in rat cerebral cortex Fulltext Access 8 Pages 2014
Histone deacetylase mediates the decrease in drebrin cluster density induced by amyloid beta oligomers Fulltext Access 8 Pages 2014
Inhibition of chemokine-like factor 1 protects against focal cerebral ischemia through the promotion of energy metabolism and anti-apoptotic effect Fulltext Access 8 Pages 2014
Apomorphine attenuates ethanol-induced neurodegeneration in the adult rat cortex Fulltext Access 8 Pages 2014
New insights into disorders of basement membranes and integrins of the kidney Fulltext Access 8 Pages 2014