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Pharmacology Research Articles

Red ginseng extracts attenuate skin inflammation in atopic dermatitis through p70 ribosomal protein S6 kinase activation
Fulltext Access 7 Pages 2018
M3 receptor is involved in the effect of penehyclidine hydrochloride reduced endothelial injury in LPS-stimulated human pulmonary microvascular endothelial cell
Fulltext Access 7 Pages 2018
Activating prostaglandin E2 receptor subtype EP4 increases secreted mucin from airway goblet cells
Fulltext Access 7 Pages 2018
Overreliance link between asthmatic subjects and short-acting β2 agonists
Fulltext Access 7 Pages 2018
Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation
Fulltext Access 7 Pages 2018
Effects of vortioxetine on biomarkers associated with glutamatergic activity in an SSRI insensitive model of depression in female rats
Fulltext Access 7 Pages 2018
The interaction of NOS1AP, DISC1, DAOA, and GSK3B confers susceptibility of early-onset schizophrenia in Chinese Han population
Fulltext Access 7 Pages 2018
Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients
Fulltext Access 7 Pages 2018
Cocaine use may induce telomere shortening in individuals with HIV infection
Fulltext Access 7 Pages 2018
Downregulation in Helios transcription factor signaling is associated with immune dysfunction in blood leukocytes of autistic children
Fulltext Access 7 Pages 2018
Analytical performance of a commercial multiplex Luminex-based cytokine panel in the rat
Fulltext Access 7 Pages 2018
Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report
Fulltext Access 7 Pages 2018
Evaluation of warming devices for lateral tail vein blood collection in mice (Mus musculus)
Fulltext Access 7 Pages 2018
Tiotropium inhibits mucin production stimulated by neutrophil elastase but not by IL-13
Fulltext Access 7 Pages 2018
Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs
Fulltext Access 7 Pages 2018
AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3
Fulltext Access 7 Pages 2018
Morin inhibits proliferation and self-renewal of CD133+ melanoma cells by upregulating miR-216a
Fulltext Access 7 Pages 2018
Genome-wide association study identifies polymorphisms associated with the analgesic effect of fentanyl in the preoperative cold pressor-induced pain test
Fulltext Access 7 Pages 2018
Mechanisms underlying the relaxation by A484954, a eukaryotic elongation factor 2 kinase inhibitor, in rat isolated mesenteric artery
Fulltext Access 7 Pages 2018
Neurotropin inhibits neuroinflammation via suppressing NF-κB and MAPKs signaling pathways in lipopolysaccharide-stimulated BV2 cells
Fulltext Access 7 Pages 2018
The uricosuric effects of dihydropyridine calcium channel blockers in vivo using urate under-excretion animal models
Fulltext Access 7 Pages 2018
Akebia saponin D alleviates hepatic steatosis through BNip3 induced mitophagy
Fulltext Access 7 Pages 2018
Piperlongumine inhibits neuroinflammation via regulating NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells
Fulltext Access 7 Pages 2018
Berberine inhibits growth and inflammatory invasive phenotypes of ectopic stromal cells: Imply the possible treatment of adenomyosis
Fulltext Access 7 Pages 2018
In vitro and in vivo anti-malignant melanoma activity of Alocasia cucullata via modulation of the phosphatase and tensin homolog/phosphoinositide 3-kinase/AKT pathway
Fulltext Access 7 Pages 2018
Endothelium-derived contraction in a model of rheumatoid arthritis is mediated via angiotensin II type 1 receptors
Fulltext Access 7 Pages 2018
New developments in the treatment of gastroparesis and functional dyspepsia
Fulltext Access 7 Pages 2018
MYD88 L265P mutation promoted malignant B cell resistance against T cell-mediated cytotoxicity via upregulating the IL-10/STAT3 cascade
Fulltext Access 7 Pages 2018
A new ligand of CD105 screened out by phage display technology provides a reliable identification of recurrent or metastasizing pleomorphic adenoma from pleomorphic adenoma
Fulltext Access 7 Pages 2018
Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells
Fulltext Access 7 Pages 2018
Punicalagin suppresses methicillin resistance of Staphylococcus aureus to oxacillin
Fulltext Access 7 Pages 2018
Dysfunction of natural killer cells mediated by PD-1 and Tim-3 pathway in anaplastic thyroid cancer
Fulltext Access 7 Pages 2018
A novel recombinant RANKL vaccine prepared by incorporation of an unnatural amino acid into RANKL and its preventive effect in a murine model of collagen-induced arthritis
Fulltext Access 7 Pages 2018
Aromatic-turmerone ameliorates imiquimod-induced psoriasis-like inflammation of BALB/c mice
Fulltext Access 7 Pages 2018
Replacement of mycophenolate mofetil with a JAK inhibitor, AS2553627, in combination with low-dose tacrolimus, for renal allograft rejection in non-human primates
Fulltext Access 7 Pages 2018
Melatonin mediated Foxp3-downregulation decreases cytokines production via the TLR2 and TLR4 pathways in H. pylori infected mice
Fulltext Access 7 Pages 2018
A simple UHPLC-PDA method with a fast dilute-and-shot sample preparation for the quantification of canrenone and its prodrug spironolactone in human urine samples
Fulltext Access 7 Pages 2018
Evaluation of the efficacy of nicotine in treatment of allergic asthma in BALB/c mice
Fulltext Access 7 Pages 2018
The inhibitory effect of Aconiti Sinomontani Radix extracts on the proliferation and migration of human synovial fibroblast cell line SW982
Fulltext Access 7 Pages 2018
Complex toxicity as disruption of adipocyte or osteoblast differentiation in human mesenchymal stem cells under the mixed condition of TBBPA and TCDD
Fulltext Access 7 Pages 2018
Kobophenol A Isolated from Roots of Caragana sinica (Buc'hoz) Rehder Exhibits Anti-inflammatory Activity by Regulating NF-κB Nuclear Translocation in J774A.1 Cells
Fulltext Access 7 Pages 2018
Evaluation of genotoxicity of Euphorbia triaculeata Forssk. extract on mice bone marrow cells in vivo
Fulltext Access 7 Pages 2018
Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells
Fulltext Access 7 Pages 2018
Influence of smoking and smoking cessation on levels of urinary 11-dehydro thromboxane B2
Fulltext Access 7 Pages 2018
Protective effects of Asparagus officinalis extract against Bisphenol A- induced toxicity in Wistar rats
Fulltext Access 7 Pages 2018
28-day inhalation toxicity of 3-methoxybutyl chloroformate in rats
Fulltext Access 7 Pages 2018
Hyperosmolal vaginal lubricants markedly reduce epithelial barrier properties in a three-dimensional vaginal epithelium model
Fulltext Access 7 Pages 2018
Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death
Fulltext Access 7 Pages 2018
Prompt treatment with uridine triacetate improves survival and reduces toxicity due to fluorouracil and capecitabine overdose or dihydropyrimidine dehydrogenase deficiency
Fulltext Access 7 Pages 2018
Polyphyllin I modulates MALAT1/STAT3 signaling to induce apoptosis in gefitinib-resistant non-small cell lung cancer
Fulltext Access 7 Pages 2018
Rescue of iCIKs transfer from PD-1/PD-L1 immune inhibition in patients with resectable tongue squamous cell carcinoma (TSCC)
Fulltext Access 7 Pages 2018
Long-term administration of pDC-Stimulative Lactococcus lactis strain decelerates senescence and prolongs the lifespan of mice
Fulltext Access 7 Pages 2018
Donor and recipient P450 gene polymorphisms influence individual pharmacological effects of tacrolimus in Chinese liver transplantation patients
Fulltext Access 7 Pages 2018
Dipeptidyl peptidase-4 inhibitors (DPP-4i) combined with vitamin D3: An exploration to treat new-onset type 1 diabetes mellitus and latent autoimmune diabetes in adults in the future
Fulltext Access 7 Pages 2018
Azithromycin ameliorates OVA-induced airway remodeling in Balb/c mice via suppression of epithelial-to-mesenchymal transition
Fulltext Access 7 Pages 2018
Moracin M inhibits lipopolysaccharide-induced inflammatory responses in nucleus pulposus cells via regulating PI3K/Akt/mTOR phosphorylation
Fulltext Access 7 Pages 2018
Cirsitakaoside isolated from Premna szemaoensis reduces LPS-induced inflammatory responses in vitro and in vivo
Fulltext Access 7 Pages 2018
Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients
Fulltext Access 7 Pages 2018
Monocyte activation and inflammation can exacerbate Treg/Th17 imbalance in infants with neonatal necrotizing enterocolitis
Fulltext Access 7 Pages 2018
Clonorchis sinensis cyclophilin A immunization protected mice from CLP-induced sepsis
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Emodin ameliorates ulcerative colitis by the flagellin-TLR5 dependent pathway in mice
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Dihydromyricetin relieves rheumatoid arthritis symptoms and suppresses expression of pro-inflammatory cytokines via the activation of Nrf2 pathway in rheumatoid arthritis model
Fulltext Access 7 Pages 2018
Geniposide improves hepatic inflammation in diabetic db/db mice
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Phenotypic and functional profile of Th17 and Treg cells in allergic fungal sinusitis
Fulltext Access 7 Pages 2018
Relationship between blood parameters and Clonorchis sinensis infection: A retrospective single center study
Fulltext Access 7 Pages 2018
A new flavonoid from Stellera chamaejasme L., stechamone, alleviated 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in a murine model
Fulltext Access 7 Pages 2018
AGE-RAGE axis blockade in diabetic nephropathy: Current status and future directions
Fulltext Access 7 Pages 2018
Characterization and molecular basis for the block of Kv1.3 channels induced by carvedilol in HEK293 cells
Fulltext Access 7 Pages 2018
The effect of zinc supplementation on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials
Fulltext Access 7 Pages 2018
Osteoactivin inhibits dexamethasone-induced osteoporosis through up-regulating integrin β1 and activate ERK pathway
Fulltext Access 7 Pages 2018
CPT1A regulates breast cancer-associated lymphangiogenesis via VEGF signaling
Fulltext Access 7 Pages 2018
Modulation of autophagy as new approach in mesenchymal stem cell-based therapy
Fulltext Access 7 Pages 2018
Functional relevance of SATB1 in immune regulation and tumorigenesis
Fulltext Access 7 Pages 2018
Novel approaches in the treatment of diabetic cardiomyopathy
Fulltext Access 7 Pages 2018
Rho kinase, a potential target in the treatment of metabolic syndrome
Fulltext Access 7 Pages 2018
Phorbol ester (PMA)-treated U937 cells cultured on type I collagen-coated dish express a lower production of pro-inflammatory cytokines through lowered ROS levels in parallel with cell aggregate formation
Fulltext Access 7 Pages 2018
Altered TNF-α response by Aconibal® and methotrexate in a lipopolysaccharide-induced setting of inflammatory conditions: Potential on a synergistic combination
Fulltext Access 7 Pages 2018
Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination
Fulltext Access 7 Pages 2018
Osteon Myospalacem Baileyi attenuates osteoclast differentiation through RANKL induced NFAT pathways
Fulltext Access 7 Pages 2018
Anti-tumour necrosis factor-α antibodies and B cell homeostasis in human inflammatory bowel diseases
Fulltext Access 7 Pages 2018
TNFα induces tolerant production of CXC chemokines in colorectal cancer HCT116 cells via A20 inhibition of ERK signaling
Fulltext Access 7 Pages 2018
Esculentoside A specifically binds to ribosomal protein S3a and impairs LPS-induced signaling in macrophages
Fulltext Access 7 Pages 2018
Molecular mechanisms of anti-inflammatory effect of chrysophanol, an active component of AST2017-01 on atopic dermatitis in vitro models
Fulltext Access 7 Pages 2018
Selective inhibition of IDO1, D-1-methyl-tryptophan (D-1MT), effectively increased EpCAM/CD3-bispecific BiTE antibody MT110 efficacy against IDO1hibreast cancer via enhancing immune cells activity
Fulltext Access 7 Pages 2018
Effects of guluronic acid (G2013) on SHIP1, SOCS1 induction and related molecules in TLR4 signaling pathway
Fulltext Access 7 Pages 2018
Plumbagin suppresses the human large cell lung cancer cell lines by inhibiting IL-6/STAT3 signaling in vitro
Fulltext Access 7 Pages 2018
Isorhamnetin, the active constituent of a Chinese herb Hippophae rhamnoides L, is a potent suppressor of dendritic-cell maturation and trafficking
Fulltext Access 7 Pages 2018
Interleukin-37 alleviates airway inflammation and remodeling in asthma via inhibiting the activation of NF-κB and STAT3 signalings
Fulltext Access 7 Pages 2018
The unique DEK oncoprotein in women's health: A potential novel biomarker
Fulltext Access 7 Pages 2018
Iodine excess did not affect the global DNA methylation status and DNA methyltransferase expression in T and B lymphocytes from NOD.H-2h4 and Kunming mice
Fulltext Access 7 Pages 2018
Oxymatrine prevents synovial inflammation and migration via blocking NF-κB activation in rheumatoid fibroblast-like synoviocytes
Fulltext Access 7 Pages 2018
Sodium butyrate alleviates LPS-induced acute lung injury in mice via inhibiting HMGB1 release
Fulltext Access 7 Pages 2018
Passive immunization against methicillin resistant Staphylococcus aureus recombinant PBP2a in sepsis model of mice: Comparable results with antibiotic therapy
Fulltext Access 7 Pages 2018
Oleamide suppresses inflammatory responses in LPS-induced RAW264.7 murine macrophages and alleviates paw edema in a carrageenan-induced inflammatory rat model
Fulltext Access 7 Pages 2018
Expression of B7-H2 on CD8+ T cells in colorectal cancer microenvironment and its clinical significance
Fulltext Access 7 Pages 2018
Cortisol inhibits NF-κB and MAPK pathways in LPS activated bovine endometrial epithelial cells
Fulltext Access 7 Pages 2018
Th17 immune responses in Brazilian dyslipidemic patients with atherosclerosis
Fulltext Access 7 Pages 2018
Roflumilast, type 4 phosphodiesterase inhibitor, attenuates inflammation in rats with ulcerative colitis via down-regulation of iNOS and elevation of cAMP
Fulltext Access 7 Pages 2018
Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway
Fulltext Access 7 Pages 2018
IL-17A promotes the formation of deep vein thrombosis in a mouse model
Fulltext Access 7 Pages 2018
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