Involvement of the midbrain tectum in the unconditioned fear promoted by morphine withdrawal Fulltext Access 7 Pages 2008
Electrophysiology-based analysis of human histamine H4 receptor pharmacology using GIRK channel coupling in Xenopus oocytes Fulltext Access 7 Pages 2008
Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells Fulltext Access 7 Pages 2008
Protective effects of protopine on hydrogen peroxide-induced oxidative injury of PC12 cells via Ca2+ antagonism and antioxidant mechanisms Fulltext Access 7 Pages 2008
Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits Fulltext Access 7 Pages 2008
Effects of lactone derivatives on aromatase (CYP19) activity in H295R human adrenocortical and (anti)androgenicity in transfected LNCaP human prostate cancer cells Fulltext Access 7 Pages 2008
A novel compound from Casearia esculenta (Roxb.) root and its effect on carbohydrate metabolism in streptozotocin-diabetic rats Fulltext Access 7 Pages 2008
8-Prenylkaempferol suppresses inducible nitric oxide synthase expression through interfering with JNK-mediated AP-1 pathway in murine macrophages Fulltext Access 7 Pages 2008
Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist Fulltext Access 7 Pages 2008
Cardiovascular responses to intravenous administration of human hemokinin-1 and its truncated form hemokinin-1(4-11) in anesthetized rats Fulltext Access 7 Pages 2008
Comparison of the binding affinity of CGP-12177A at recombinant rat α1D-adrenoceptors expressed in BHK-21 cell membranes and α1-adrenoceptors present in rat cerebral cortex membranes Fulltext Access 7 Pages 2008
Vitamin D2 supplementation induces the development of aortic stenosis in rabbits: Interactions with endothelial function and thioredoxin-interacting protein Fulltext Access 7 Pages 2008
Carteolol, a non-conventional partial agonist of β1-adrenoceptors, relaxes phenylephrine-constricted rat aorta through antagonism at α1-adrenoceptors Fulltext Access 7 Pages 2008
Nitric oxide enhances Oct-4 expression in bone marrow stem cells and promotes endothelial differentiation Fulltext Access 7 Pages 2008
Peripheral nerve injury alters spinal nicotinic acetylcholine receptor pharmacology Fulltext Access 7 Pages 2008
Mechanisms of α7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment Fulltext Access 7 Pages 2008
Menthol shares general anesthetic activity and sites of action on the GABAA receptor with the intravenous agent, propofol Fulltext Access 7 Pages 2008
Involvements of PHI-nitric oxide and PACAP-BK channel in the sustained relaxation of mouse gastric fundus Fulltext Access 7 Pages 2008
Adenosine A2A receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC Fulltext Access 7 Pages 2008
Increased phosphodiesterase 3A/4B expression after angioplasty and the effect on VASP phosphorylation Fulltext Access 7 Pages 2008
Effect of propofol on calcium homeostasis in hypoxia-reoxygenated neonatal rat cardiomyocytes Fulltext Access 7 Pages 2008
Evidence for a role of endogenous neurotensin in the development of sensitization to the locomotor stimulant effect of morphine Fulltext Access 7 Pages 2008
Melatonin reverses the expression of morphine-induced conditioned place preference through its receptors within central nervous system in mice Fulltext Access 7 Pages 2008
The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats Fulltext Access 7 Pages 2008
Prenatal exposure to endotoxin in rats attenuates the allergic airways eosinophil infiltration in the adult offspring: Role of inducible nitric oxide synthase activation Fulltext Access 7 Pages 2008
Regulation of peroxisome proliferator-activated receptor-α expression during lung inflammation Fulltext Access 7 Pages 2008
Montelukast inhibits inflammatory responses in small airways of the Guinea-pig Fulltext Access 7 Pages 2008
Manipulations of core temperatures in ischemia-reperfusion lung injury in rabbits Fulltext Access 7 Pages 2008
Lung function and symptom improvement with fluticasone propionate/salmeterol and ipratropium bromide/albuterol in COPD: Response by beta-agonist reversibility Fulltext Access 7 Pages 2008
Interleukin-1β up-regulates tumor necrosis factor receptors in the mouse airways Fulltext Access 7 Pages 2008
A comparative study of grape seed extract and vitamin E effects on silica-induced pulmonary fibrosis in rats Fulltext Access 7 Pages 2008
Bronchodilator efficacy of the fixed combination of ipratropium and albuterol compared to albuterol alone in moderate-to-severe persistent asthma Fulltext Access 7 Pages 2008
Stem cells and cell therapies for cystic fibrosis and other lung diseases Fulltext Access 7 Pages 2008
Efficiency of lornoxicam in lung and trachea injury caused by peroxynitrite Fulltext Access 7 Pages 2008
Chronic inhalation of nebulized levalbuterol does not increase mucociliary clearance in healthy subjects Fulltext Access 7 Pages 2008
Dose-dependent inhibition of allergic inflammation and bronchial hyperresponsiveness by budesonide in ovalbumin-sensitised Brown-Norway rats Fulltext Access 7 Pages 2008
Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction Fulltext Access 7 Pages 2008
Efficacy and safety of formoterol delivered through the Novolizer®, a novel dry powder inhaler (DPI) compared with a standard DPI in patients with moderate to severe asthma Fulltext Access 7 Pages 2008
Effect of theophylline on endogenous hydrogen sulfide production in patients with COPD Fulltext Access 7 Pages 2008
Fluticasone or montelukast for preschool children with asthma-like symptoms: Randomized controlled trial Fulltext Access 7 Pages 2008
The forgotten message from gold: FVC is a primary clinical outcome measure of bronchodilator reversibility in COPD Fulltext Access 7 Pages 2008
Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats Fulltext Access 7 Pages 2008
CGP12177-induced haemodynamic and vascular effects in normotensive and hypertensive rats Fulltext Access 7 Pages 2008
Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum Fulltext Access 7 Pages 2008
Role of endogenous endothelin-1 in post-ischemic cardiac dysfunction and norepinephrine overflow in rat hearts Fulltext Access 7 Pages 2008
Effect of forced chronic oral nicotine exposure on intravenous self-administration and rewarding properties of acute nicotine Fulltext Access 7 Pages 2008
Pinocembrin prevents glutamate-induced apoptosis in SH-SY5Y neuronal cells via decrease of bax/bcl-2 ratio Fulltext Access 7 Pages 2008
Resveratrol protects primary rat hepatocytes against oxidative stress damage:: Activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes Fulltext Access 7 Pages 2008
Involvement of hyperglycemia in deposition of aggregated protein in glomeruli of diabetic mice Fulltext Access 7 Pages 2008
Novel effects of macrostemonoside A, a compound from Allium macrostemon Bung, on hyperglycemia, hyperlipidemia, and visceral obesity in high-fat diet-fed C57BL/6 mice Fulltext Access 7 Pages 2008
Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice Fulltext Access 7 Pages 2008
Lercanidipine decreases vascular matrix metalloproteinase-2 activity and protects against vascular dysfunction in diabetic rats Fulltext Access 7 Pages 2008
In vitro and in vivo profiling of fadolmidine, a novel potent α2-adrenoceptor agonist with local mode of action Fulltext Access 7 Pages 2008
Neuroadaptive changes in the rat brain GABAB receptors after withdrawal from cocaine self-administration Fulltext Access 7 Pages 2008
Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-κB in RAW 264.7 cells Fulltext Access 7 Pages 2008
The relaxant effect of okadaic acid on canine basilar artery involves activation of PKCα and phosphorylation of the myosin light chain at Thr-9 Fulltext Access 7 Pages 2008
Putrescine modulation of acute activation of the β-adrenergic system in the left atrium of rat Fulltext Access 7 Pages 2008
The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats Fulltext Access 7 Pages 2008
Activation of high conductance Ca2+-activated K+ channels by sodium tanshinoneII-A sulfonate (DS-201) in porcine coronary artery smooth muscle cells Fulltext Access 7 Pages 2008
ent-pimara-8(14), 15-dien-19-oic acid isolated from the roots of Aralia cordata inhibits induction of inflammatory mediators by blocking NF-κB activation and mitogen-activated protein kinase pathways Fulltext Access 7 Pages 2008
Resveratrol ameliorates hepatic injury via the mitochondrial pathway in rats with severe acute pancreatitis Fulltext Access 7 Pages 2008
Characterization of aripiprazole partial agonist activity at human dopamine D3 receptors Fulltext Access 7 Pages 2008
Effects of a Western diet versus high glucose on endothelium-dependent relaxation in murine micro- and macro-vasculature Fulltext Access 7 Pages 2008
PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate Fulltext Access 7 Pages 2008
Paclitaxel–octreotide conjugates in tumor growth inhibition of A549 human non-small cell lung cancer xenografted into nude mice Fulltext Access 7 Pages 2008
Source of the elevation Ca2+ evoked by 15-HETE in pulmonary arterial myocytes Fulltext Access 7 Pages 2008
Identification and characterization of pseudoirreversible nonpeptide antagonists of the neuropeptide Y Y5 receptor and development of a novel Y5-selective radioligand Fulltext Access 7 Pages 2008
TP receptor-mediated release of eosinophil chemotactic activity from human bronchial smooth muscle cells Fulltext Access 7 Pages 2008
Excitatory and inhibitory 5-hydroxytryptamine (5-HT) receptors expressed in the isolated porcine uterine muscles Fulltext Access 7 Pages 2008
Ouabain treatment changes the role of endothelial factors in rat resistance arteries Fulltext Access 7 Pages 2008
Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion Fulltext Access 7 Pages 2008
Antinociceptive and anti-allodynic effects of oral PL37, a complete inhibitor of enkephalin-catabolizing enzymes, in a rat model of peripheral neuropathic pain induced by vincristine Fulltext Access 7 Pages 2008
PAR-5359, a well-balanced PPARα/γ dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo Fulltext Access 7 Pages 2008
The novel inhibitor of the heterotrimeric G-protein complex, BIM-46187, elicits anti-hyperalgesic properties and synergizes with morphine Fulltext Access 7 Pages 2008
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells Fulltext Access 7 Pages 2008
The antipsychotics clozapine and olanzapine increase plasma glucose and corticosterone levels in rats: Comparison with aripiprazole, ziprasidone, bifeprunox and F15063 Fulltext Access 7 Pages 2008
Targeted disruption of the A2A adenosine receptor reduces in-vitro prostate contractility in mature mice Fulltext Access 7 Pages 2008
Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: Analysis of serotonin and noradrenaline transporter binding Fulltext Access 7 Pages 2008
Feeding conditions differentially affect the neurochemical and behavioral effects of dopaminergic drugs in male rats Fulltext Access 7 Pages 2008
Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression Fulltext Access 7 Pages 2008
Anti-inflammatory treatment with the p38 mitogen-activated protein kinase inhibitor SB239063 is neuroprotective, decreases the number of activated microglia and facilitates neurogenesis in oxygen–glucose-deprived hippocampal slice cultures Fulltext Access 7 Pages 2008
Blockade of anaesthetic-induced preconditioning in the hyperglycaemic myocardium: The regulation of different mitogen-activated protein kinases Fulltext Access 7 Pages 2008
A quassinoid 6α-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation Fulltext Access 7 Pages 2008
Cloning and pharmacological characterization of the dog histamine H4 receptor Fulltext Access 7 Pages 2008
Clomipramine block of the hERG K+ channel: Accessibility to F656 and Y652 Fulltext Access 7 Pages 2008
Neurokinin-1 receptor antagonists modulate brain noradrenaline and serotonin interactions Fulltext Access 7 Pages 2008
Physiological levels of glutamine prevent morphine-induced preconditioning in the isolated rat heart Fulltext Access 7 Pages 2008
Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-γ) agonist balaglitazone Fulltext Access 7 Pages 2008
Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells Fulltext Access 7 Pages 2008
Novel triple neurokinin receptor antagonist CS-003 inhibits respiratory disease models in guinea pigs Fulltext Access 7 Pages 2008
Resveratrol modulates pyrogallol-induced changes in hepatic toxicity markers, xenobiotic metabolizing enzymes and oxidative stress Fulltext Access 7 Pages 2008
Role of nitric oxide and carbon monoxide in Nω-Nitro-l-arginine methyl ester-resistant acetylcholine-induced relaxation in chicken carotid artery Fulltext Access 7 Pages 2008
Amelioration of neurological and biochemical deficits by peroxynitrite decomposition catalysts in experimental diabetic neuropathy Fulltext Access 7 Pages 2008
Possible participation of the nitric oxide-cyclic GMP-protein kinase G-K+ channels pathway in the peripheral antinociception of melatonin Fulltext Access 7 Pages 2008
Litebamine, a phenanthrene alkaloid from the wood of Litsea cubeba, inhibits rat smooth muscle cell adhesion and migration on collagen Fulltext Access 7 Pages 2008
Preconditioning with acute and chronic lithium administration reduces ischemia/reperfusion injury mediated by cyclooxygenase not nitric oxide synthase pathway in isolated rat heart Fulltext Access 7 Pages 2008
Hydromorphone efficacy and treatment protocol impact on tolerance and μ-opioid receptor regulation Fulltext Access 7 Pages 2008