Orexin/hypocretin modulation of the basal forebrain cholinergic system: Insights from in vivo microdialysis studies Fulltext Access 7 Pages 2008
Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms Fulltext Access 7 Pages 2008
Computational models for prediction of interactions with ABC-transporters Fulltext Access 7 Pages 2008
The value of proteasome inhibition in cancer: Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor? Fulltext Access 7 Pages 2008
The heterozygous Sod2+/− mouse: modeling the mitochondrial role in drug toxicity Fulltext Access 7 Pages 2008
The differential effects of acetaminophen on lipopolysaccharide induced hyperalgesia in various mouse pain models Fulltext Access 7 Pages 2008
Desipramine blocks alcohol-induced anxiety- and depressive-like behaviors in two rat strains Fulltext Access 7 Pages 2008
Intrinsic effects of AM4113, a putative neutral CB1 receptor selective antagonist, on open-field behaviors in rats Fulltext Access 7 Pages 2008
Central actions of arginine vasopressin and a V1a receptor antagonist on maternal aggression, maternal behavior, and grooming in lactating rats Fulltext Access 7 Pages 2008
Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082 Fulltext Access 7 Pages 2008
Nicotine place preference in a biased conditioned place preference design Fulltext Access 7 Pages 2008
Ejaculatory response induced by a 5-HT2 receptor agonist m-CPP in rats: Differential roles of 5-HT2 receptor subtypes Fulltext Access 7 Pages 2008
Regulation of cognition and symptoms of psychosis: Focus on GABAA receptors and glycine transporter 1` Fulltext Access 7 Pages 2008
GABA-A receptors and the response to CO2 inhalation — A translational trans-species model of anxiety? Fulltext Access 7 Pages 2008
Product-related research: how research can contribute to successful life-cycle management Fulltext Access 7 Pages 2008
Cardiac Pharmacokinetics and Inotropic Response of Verapamil in Rats With Endotoxemia Fulltext Access 7 Pages 2008
Facile and Sensitive Determination of Selenium (IV) in Pharmaceutical Formulations by Flow Injection Spectrophotometry Fulltext Access 7 Pages 2008
Feeding specific glutamate surge in the rat lateral hypothalamus revealed by low-flow push–pull perfusion Fulltext Access 7 Pages 2008
Application of LC/MS and related techniques to high-throughput drug discovery Fulltext Access 7 Pages 2008
Human metabolic network reconstruction and its impact on drug discovery and development Fulltext Access 7 Pages 2008
Cardiotoxicity of the new cancer therapeutics – mechanisms of, and approaches to, the problem Fulltext Access 7 Pages 2008
Addressing informatics challenges in Translational Research with workflow technology Fulltext Access 7 Pages 2008
Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: Insulin and melanocortins Fulltext Access 7 Pages 2008
Cocaine effects on behavioral responding to a novel object placed in a familiar environment Fulltext Access 7 Pages 2008
Antagonism of phencyclidine-induced stimulus control in the rat by other psychoactive drugs Fulltext Access 7 Pages 2008
A comparison of the effects of different operant training experiences and dietary restriction on the reinstatement of cocaine-seeking in rats Fulltext Access 7 Pages 2008
The rewarding efficacy of brain stimulation and its modulation by dopaminergic drugs in young adult and old BN F344F1 rats Fulltext Access 7 Pages 2008
Inhibition of the development of morphine tolerance by a potent dual μ-/δ-opioid antagonist, H-Dmt-Tic-Lys-NH-CH2-Ph Fulltext Access 7 Pages 2008
Cocaine conditioned behavior: A cocaine memory trace or an anti-habituation effect Fulltext Access 7 Pages 2008
CB1 receptor-dependent and -independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212-2 Fulltext Access 7 Pages 2008
Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures Fulltext Access 7 Pages 2008
Pretreatment with subeffective doses of Rimonabant attenuates orexigenic actions of orexin A-hypocretin 1 Fulltext Access 7 Pages 2008
Intracellular Ca2+ dynamics of hippocampal interneurons following nicotinic acetylcholine receptor activation Fulltext Access 7 Pages 2008
Trans-synaptic regulation of calmodulin gene expression after experimentally induced orofacial inflammation and subsequent corticosteroid treatment in the principal sensory and motor trigeminal nuclei of the rat Fulltext Access 7 Pages 2008
Ethanol and acetaldehyde alter NTPDase and 5â²-nucleotidase from zebrafish brain membranes Fulltext Access 7 Pages 2008
Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease Fulltext Access 7 Pages 2008
Isoform specificity of P2X2 purinergic receptor C-terminus binding to tubulin Fulltext Access 7 Pages 2008
Physiological and psychological symptoms and predictors in early nicotine withdrawal Fulltext Access 7 Pages 2008
Developmental lead exposure attenuates methamphetamine dose-effect self-administration performance and progressive ratio responding in the male rat Fulltext Access 7 Pages 2008
Behavioral effects of saredutant, a tachykinin NK2 receptor antagonist, in experimental models of mood disorders under basal and stress-related conditions Fulltext Access 7 Pages 2008
Effect of drug-paired exteroceptive stimulus presentations on methamphetamine reinstatement in rats Fulltext Access 7 Pages 2008
Decreased brain reward function during nicotine withdrawal in C57BL6 mice: Evidence from intracranial self-stimulation (ICSS) studies Fulltext Access 7 Pages 2008
D4 receptor deficiency in mice has limited effects on impulsivity and novelty seeking Fulltext Access 7 Pages 2008
Role of systemic endocannabinoid CB-1 receptor antagonism in the acquisition and expression of fructose-conditioned flavor–flavor preferences in rats Fulltext Access 7 Pages 2008
Overlapping, but not identical, discriminative stimulus effects of the neuroactive steroid pregnanolone and ethanol Fulltext Access 7 Pages 2008
Changes in brain oxidative metabolism induced by inhibitory avoidance learning and acute administration of amitriptyline Fulltext Access 7 Pages 2008
Development of conditioned place preference induced by intra-accumbens infusion of amphetamine is attenuated by co-infusion of dopamine D1 and D2 receptor antagonists Fulltext Access 7 Pages 2008
5-HT1A receptors of the lateral septum regulate inhibitory avoidance but not escape behavior in rats Fulltext Access 7 Pages 2008
Systemic administration of the adenosine A2A agonist CGS 21680 induces sedation at doses that suppress lever pressing and food intake Fulltext Access 7 Pages 2008
Chronic intermittent nicotine treatment dose-dependently alters serotonergic neurons response to citalopram in the rat Fulltext Access 7 Pages 2008
Behavioral perseveration and impairment of long-term memory in rats after intrahippocampal injection of kainic acid in subconvulsive dose Fulltext Access 7 Pages 2008
Different cellular sources and different roles of adenosine: A1 receptor-mediated inhibition through astrocytic-driven volume transmission and synapse-restricted A2A receptor-mediated facilitation of plasticity Fulltext Access 8 Pages 2008
CB1-cannabinoid receptors are involved in the modulation of non-synaptic [3H]serotonin release from the rat hippocampus Fulltext Access 8 Pages 2008
Oxidative stress on the astrocytes in culture derived from a senescence accelerated mouse strain Fulltext Access 8 Pages 2008
Noladin ether, a putative endocannabinoid, inhibits μ-opioid receptor activation via CB2 cannabinoid receptors Fulltext Access 8 Pages 2008
Exposure to movement in chronic back pain: Evidence of successful generalization across a reaching task Fulltext Access 8 Pages 2008
Effects of penicillin on procaine-elicited bursts of potential in central neuron of snail, Achatina fulica Fulltext Access 8 Pages 2008
p53 gene expression is modulated by endocrine disrupting chemicals in the hermaphroditic fish, Kryptolebias marmoratus Fulltext Access 8 Pages 2008
The neurotoxic effects of manganese on the dopaminergic innervation of the gill of the bivalve mollusc, Crassostrea virginica Fulltext Access 8 Pages 2008
Copper deficient rats and mice both develop anemia but only rats have lower plasma and brain iron levels Fulltext Access 8 Pages 2008
Mercury toxicity in livers of northern pike (Esox lucius) from Isle Royale, USA Fulltext Access 8 Pages 2008
Influence of field and experimental exposure of mussels (Mytilus sp.) to nickel and vanadium on metallothionein concentration Fulltext Access 8 Pages 2008
Have wing morphology or flight kinematics evolved for extreme high altitude migration in the bar-headed goose? Fulltext Access 8 Pages 2008
Evidence of anoxia-induced channel arrest in the brain of the goldfish (Carassius auratus) Fulltext Access 8 Pages 2008
Theoretical considerations underlying Na+ uptake mechanisms in freshwater fishes Fulltext Access 8 Pages 2008
Heat shock protein (Hsp70) induced by a mild heat shock slightly moderates plasma osmolarity increases upon salinity transfer in rainbow trout (Oncorhynchus mykiss) Fulltext Access 8 Pages 2008
Impairment of the stress response in matrinxã juveniles (Brycon amazonicus) exposed to low concentrations of phenol Fulltext Access 8 Pages 2008
Hepatic cytochrome P450 enzymes belonging to the CYP2C subfamily from an Australian marsupial, the koala (Phascolarctos cinereus) Fulltext Access 8 Pages 2008
Isolation and characterization of a hyaluronidase from the venom of Chinese red scorpion Buthus martensi Fulltext Access 8 Pages 2008
Acute effects of diflubenzuron on the freshwater fish Prochilodus lineatus Fulltext Access 8 Pages 2008
Disruption of circulation by ethanol promotes fetal alcohol spectrum disorder (FASD) in medaka (Oryzias latipes) embryogenesis Fulltext Access 8 Pages 2008
Metallothionein genes from hydrothermal crabs (Bythograeidae, Decapoda): Characterization, sequence analysis, gene expression and comparison with coastal crabs Fulltext Access 8 Pages 2008
ACL-I, a lectin from the marine sponge Axinella corrugata: Isolation, characterization and chemotactic activity Fulltext Access 8 Pages 2008
Prise en charge des surdosages en antivitamine K, des situations à risques hémorragiques et des accidents hémorragiques chez les patients traités par antivitamine K en ville et en milieu hospitalier Fulltext Access 8 Pages 2008