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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

Developmental changes in the response of murine cerebellar granule cells to nitric oxide
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Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury
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Over-expressed human divalent metal transporter 1 is involved in iron accumulation in MES23.5 cells
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Dose-dependent and sequence-sensitive effects of amyloid-β peptide on neurosteroidogenesis in human neuroblastoma cells
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Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons
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Expression of functional dopaminergic phenotype in purified cultured Müller cells from vertebrate retina
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Down-regulation of norepinephrine transporter expression on membrane surface induced by chronic administration of desipramine and the antagonism by co-administration of local anesthetics in mice
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An index of 5-HT synthesis changes during early antidepressant treatment: α-[11C]methyl-l-tryptophan PET study
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Effect of ocular hypertension on retinal GABAergic activity
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Neurosteroid modulation of GABAA receptors: Molecular determinants and significance in health and disease
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Electrophysiological properties and gap junction coupling of striatal astrocytes
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Increases in cholinergic neurotransmission measured by using choline-sensitive microelectrodes: Enhanced detection by hydrolysis of acetylcholine on recording sites?
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Reciprocal inhibition of G-protein signaling is induced by CB1 cannabinoid and GABAB receptor interactions in rat hippocampal membranes
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Mitochondrial oxygen consumption inhibition importance for TMT-dependent cell death in undifferentiated PC12 cells
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Chromatin structure and expression of synapsin I and synaptophysin in retinal precursor cells
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Lateralization of hippocampal nitric oxide mediator system in people with Alzheimer disease, multi-infarct dementia and schizophrenia
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Osthole and imperatorin, the active constituents of Cnidium monnieri (L.) Cusson, facilitate glutamate release from rat hippocampal nerve terminals
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Manganese activates the mitochondrial apoptotic pathway in rat astrocytes by modulating the expression of proteins of the Bcl-2 family
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Lysophosphatidylcholine induces delayed myelination in the juvenile ventral hippocampus and behavioral alterations in adulthood
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l-NAME prevents GM1 ganglioside-induced vasodilation in the rat brain
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Reverse Na+/Ca2+-exchange mediated Ca2+-entry and noradrenaline release in Na+-loaded peripheral sympathetic nerves
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From a glucocentric to a lipocentric approach towards metabolic syndrome
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Protein interaction predictions from diverse sources
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Zebrafish: a predictive model for assessing drug-induced toxicity
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Drug name recognition and classification in biomedical texts: A case study outlining approaches underpinning automated systems
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Sumatriptan Succinate Transdermal Delivery Systems for The Treatment of Migraine
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Auditory gating in rat hippocampus and medial prefrontal cortex: Effect of the cannabinoid agonist WIN55,212-2
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HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo
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Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells
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Striatal 5-HT1A receptor stimulation reduces D1 receptor-induced dyskinesia and improves movement in the hemiparkinsonian rat
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Neonatal administration of N-omega-nitro-l-arginine induces permanent decrease in NO levels and hyperresponsiveness to locomotor activity by d-amphetamine in postpubertal rats
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Professor William I. Higuchi: Teacher and Scientist
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Delayed Release Tablet Dissolution Related to Coating Thickness by Terahertz Pulsed Image Mapping
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On the role of granule yield strength for the compactibility of granular solids
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Tricalcium Phosphate Delayed Release Formulation for Oral Delivery of Insulin: A Proof-of-Concept Study
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The effect of punch tilting in evaluating powder densification in a rotary tablet machine
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Multivariate Calibration of Covalent Aggregate Fraction to the Raman Spectrum of Regular Human Insulin
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Echogenic Liposome Compositions for Increased Retention of Ultrasound Reflectivity at Physiologic Temperature
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Natural products in drug discovery
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Nitration of soluble proteins in organotypic culture models of Parkinson's disease
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Angiopoietin-like protein 1 decreases blood brain barrier damage and edema following focal cerebral ischemia in mice
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Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen–glucose deprivation
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Isoflurane anesthesia inhibits clozapine- and risperidone-induced dopamine release and anesthesia-induced changes in dopamine metabolism was modified by fluoxetine in the rat striatum: An in vivo microdialysis study
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Effect of novel arecoline thiazolidinones as muscarinic receptor 1 agonist in Alzheimer's dementia models
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Neuroprotective effect of cobalt chloride on hypobaric hypoxia-induced oxidative stress
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Biochemical effects of pretreatment with vitamins E and C in rats submitted to intrastriatal hypoxanthine administration
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Overactivation of calcineurin induced by amyloid-beta and prion proteins
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Sex-differences and stress: Effects on regional high and low affinity [3H]GABA binding
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Subregion-specific vulnerability to endoplasmic reticulum stress-induced neurotoxicity in rat hippocampal neurons
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RNAi-mediated silencing of ABCD3 gene expression in rat C6 glial cells: A model system to study PMP70 function
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Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): Possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents
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GABAA receptor subtypes underlying general anesthesia
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GABA in the female brain — Oestrous cycle-related changes in GABAergic function in the periaqueductal grey matter
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Targeted deletion of the GABRA2 gene encoding α2-subunits of GABAA receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates
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Overriding the blockade of antinociceptive actions of opioids in rats treated with extended-release naltrexone
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Unreinforced responding during limited access to heroin self-administration
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Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior
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The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively bred High-Responder and Low-Responder rats
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Changes in amygdala neural activity that occur with the extinction of context-dependent conditioned fear stress
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The effects of acute and repeated nicotine doses on spontaneous activity in male and female Sprague Dawley rats: Analysis of brain area epibatidine binding and cotinine levels
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Dexibuprofen (S(+)-isomer ibuprofen) reduces microglial activation and impairments of spatial working memory induced by chronic lipopolysaccharide infusion
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The CB1 cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus
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Nitric oxide synthase inhibition attenuates phencyclidine-induced disruption of cognitive flexibility
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Repeated administration of nicotine attenuates the development of morphine tolerance and dependence in mice
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Duration of ultrasonic vocalizations in the isolated rat pup as a behavioral measure: Sensitivity to anxiolytic and antidepressant drugs
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5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine
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Behavioral processes mediating phencyclidine-induced decreases in voluntary sucrose consumption
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Long-term cognitive deficits induced by a single, extremely low dose of tetrahydrocannabinol (THC): Behavioral, pharmacological and biochemical studies in mice
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Increased task difficulty results in greater impact of noradrenergic modulation of cognitive flexibility
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Gamma-hydroxybutyrate (GHB) reduces operant behavior without impairing working memory in rats responding under fixed-consecutive-number schedules
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Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice
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Severity of alcohol withdrawal symptoms depends on developmental stage of Long–Evans rats
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The rate of intravenous cocaine or amphetamine delivery does not influence drug-taking and drug-seeking behavior in rats
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Effects of selective serotonin2 ligands on behaviors evoked by stress in the rat
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Enhancing effect of HT008-1 on cognitive function and quality of life in cognitively declined healthy adults: A randomized, double-blind, placebo-controlled, trial
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Kinases as drug targets in the treatment of bipolar disorder
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Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug
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MEMS technology for nanobio research
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Principles for 3D/4D QSAR classification of drugs
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The design, structures and therapeutic potential of protein epitope mimetics
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The application of FAST-NMR for the identification of novel drug discovery targets
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Nanotechnology in ocular drug delivery
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Rational drug design in parasitology: trans-sialidase as a case study for Chagas disease
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Dimerization of chemokine receptors in living cells: key to receptor function and novel targets for therapy
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Snapshot PK: a rapid rodent in vivo preclinical screening approach
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Pharmacological treatments of fibromyalgia: Do complex conditions need complex therapies?
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Serotoninergic mechanisms in the treatment of obsessive–compulsive disorder
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Computational toxicology in drug development
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Demand for cocaine and food over time
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Needed: system dynamics for the drug discovery process
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Chemistry strategies in early drug discovery: an overview of recent trends
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Effect of chronic lithium treatment on D2/3 autoreceptor regulation of dopaminergic function in the rat
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Application of long-term microdialysis in circadian rhythm research
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Inhibition of cyclin-dependent kinase 5 by roscovitine impairs memory consolidation and reconsolidation in the day-old chick
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A cross-fostering study in a genetic animal model of depression: Maternal behavior and depression-like symptoms
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Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores
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Serotonergic neurotransmission mediates hypothermia induced by the N-phenylpiperazine antipsychotic prototypes LASSBio-579 and LASSBio-581
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Effects of nitric oxide synthase inhibitors in attenuating nicotine withdrawal in rats
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Influence of chronic exercise on reserpine-induced oxidative stress in rats: Behavioral and antioxidant evaluations
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Discrimination and avoidance learning in adult mice following developmental exposure to diisopropylfluorophosphate
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